Page last updated: 2024-10-25

desipramine and Affective Psychosis, Bipolar

desipramine has been researched along with Affective Psychosis, Bipolar in 85 studies

Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.

Research Excerpts

ExcerptRelevanceReference
"The authors report on a female patient with bipolar affective disorder who presented with marked eosinophilia in conjunction with pneumonia five days after a medication change from amitriptyline to desipramine (for intolerable dry mouth)."7.67Massive eosinophilic reaction to desipramine in conjunction with pneumonia. ( Clarke, RJ; Kraus, RP; Remick, RA, 1984)
"Mild myoclonus is reasonably common with various cyclic antidepressants."5.29Severe imipramine-induced myoclonus in a patient with psychotic bipolar depression, catatonia, and schizencephaly. ( Black, KJ; Kilzieh, N, 1994)
"Nefazodone is a new antidepressant exhibiting properties of selective serotonin reuptake inhibition and serotonin-2 receptor antagonism."5.29Probable nefazodone-induced mania in a patient with unreported bipolar disorder. ( Blaisdell, GD; Jermain, DM; Zaphiris, HA, 1996)
"Forty-two outpatients with major depressive disorder entered a double-blind, randomized trial of either desipramine or amitriptyline for a minimum of 6 weeks."5.06Reduced REM latency predicts response to tricyclic medication in depressed outpatients. ( Debus, JR; Feldman-Koffler, F; Giles, DE; Jarrett, RB; Orsulak, PJ; Roffwarg, HP; Rush, AJ; Weissenburger, J, 1989)
" Among the more important recent discoveries are the efficacy of the tricyclic antidepressants for panic disorder and agoraphobia with panic attacks; the use of the monoamine oxidase inhibitors for the above disorders and for atypical depression and hysteroid dysphoria; the use of propranolol for anxiety disorders and for uncontrollable violent outbursts; the antianxiety and antipanic effects of clonidine; and the usefulness of lithium in treating schizophrenia and schizoaffective disorder and for emotionally unstable character disorders."4.76Newer uses for older psychotropic medications. ( Liebowitz, MR, 1982)
"The authors report on a female patient with bipolar affective disorder who presented with marked eosinophilia in conjunction with pneumonia five days after a medication change from amitriptyline to desipramine (for intolerable dry mouth)."3.67Massive eosinophilic reaction to desipramine in conjunction with pneumonia. ( Clarke, RJ; Kraus, RP; Remick, RA, 1984)
" In the present study, thyroid functions (TFTs) and thyrotropin-releasing hormone (TRH) stimulation of thyroid-stimulating hormone (TSH) were measured before and after treatment with desipramine (DMI) in 13 men with a diagnosis of major depressive disorder."3.67The thyroid axis and desipramine treatment in depression. ( Anton, RF; Brady, KT, 1989)
"Two patients are described who developed testicular swelling and pain during treatment with desipramine."3.67Desipramine and testicular swelling in two patients. ( Thienhaus, OJ; Vogel, N, 1988)
" administration of 75 mg of desipramine on growth hormone (GH) secretion was investigated in a sample of 87 patients with major depressive disorders and in 31 normal controls."3.67Growth hormone release after desipramine in depressive illness. ( Charles, G; Decoster, C; Kerkhofs, M; Meesters, P; Mendlewicz, J; Vanderelst, M, 1985)
"The PKC activity of the major depressive disorder subjects and healthy volunteers was inhibited by desipramine, whereas that of the bipolar disorder subjects showed both inhibition and activation."2.69Different effect of desipramine on protein kinase C in platelets between bipolar and major depressive disorders. ( Aoki, S; Morishita, S; Watanabe, S, 1999)
"Although treatment of bipolar depression is a frequent clinical problem, double-blind studies of the treatment of bipolar depression are scarce."2.67A double-blind trial of bupropion versus desipramine for bipolar depression. ( Banov, M; Lafer, B; Rosenbaum, JF; Sachs, GS; Stoll, AL; Thibault, AB; Tohen, M, 1994)
"Fenfluramine 40-120 mg/day was then added to the ongoing desipramine in a placebo substitution design."2.67Fenfluramine augmentation in tricyclic-refractory depression. ( Charney, DS; Delgado, PL; Heninger, GR; Price, LH, 1990)
"It was observed that two patients with bipolar depression developed mania during crossover treatment with desipramine, while two patients with bipolar depression who were treated with zimelidine during the second treatment period did not show any symptoms of mania."2.65Comparison between zimelidine and desipramine in endogenous depression. A cross-over study. ( Aberg-Wistedt, A, 1982)
"Mild myoclonus is reasonably common with various cyclic antidepressants."1.29Severe imipramine-induced myoclonus in a patient with psychotic bipolar depression, catatonia, and schizencephaly. ( Black, KJ; Kilzieh, N, 1994)
"Treatment with desipramine (n = 26) did not alter significantly any of the model parameters and had no effect on circadian variability in any patient group."1.29Disruption of circadian MHPG rhythmicity in major depression. ( DeMet, E; Gwirtsman, HE; Halaris, A; Piletz, JE, 1994)
"Nefazodone is a new antidepressant exhibiting properties of selective serotonin reuptake inhibition and serotonin-2 receptor antagonism."1.29Probable nefazodone-induced mania in a patient with unreported bipolar disorder. ( Blaisdell, GD; Jermain, DM; Zaphiris, HA, 1996)
"Treatment with carbamazepine reduced CSF somatostatin (p less than ."1.27CSF somatostatin in affective illness and normal volunteers. ( Ballenger, JC; Gold, PW; Post, RM; Rubinow, DR, 1985)
"A 24-year-old woman with a unipolar depression had an augmented thyroid-stimulating hormone response to thyrotropin-releasing hormone (TRH), suggesting subclinical hypothyroidism."1.26Does subclinical hypothyroidism predispose to tricyclic-induced rapid mood cycles? ( Extein, I; Gold, MS; Pottash, AL, 1982)
"Desipramine was given at a dose of 50-100 mg/day for 3-5 weeks."1.26Abnormal anterior pituitary responsiveness to hypothalamic hormones in primary affective disorders. Effect of desipramine therapy. ( Brambilla, F; Massironi, R; Nobile, P; Pugnetti, L; Scarone, S, 1982)

Research

Studies (85)

TimeframeStudies, this research(%)All Research%
pre-199070 (82.35)18.7374
1990's15 (17.65)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
OLESEN, KM1
HAASE, HJ1
KOESTER, H1
KOENIG, M1
BLEKER, A1
CMYRAL, K1
HOFMANN, G1
ALNAES, R2
KRISTIANSEN, J2
SEGERS, J1
NUYTS, JA1
LAPOLLA, A1
Genazzani, AR1
Petraglia, F1
Facchinetti, F1
Monittola, C1
Scarone, S3
Brambilla, F3
Maas, JW2
Huang, Y1
Liebowitz, MR2
Extein, I5
Gold, MS3
Pottash, AL3
Aberg-Wistedt, A2
Linnoila, M4
Karoum, F2
Potter, WZ7
Anton, RF2
Sexauer, JD1
Randall, CL1
Sternbach, HA1
Price, LH2
Charney, DS2
Heninger, GR2
Garvey, MJ1
Johnson, RA1
Valentine, RH1
Schuster, V1
Greden, JF1
Price, HL1
Genero, N1
Feinberg, M1
Levine, S1
Muscettola, G3
Pickar, D1
Goodwin, FK6
Kraus, RP1
Clarke, RJ1
Remick, RA1
Lesser, I1
Waters, BG1
Lapierre, YD1
Massironi, R1
Nobile, P2
Pugnetti, L2
Nelson, JC1
Schottenfeld, RS1
Conrad, CD1
Prange, AJ1
Post, RM2
Lipton, MA1
Baloh, RW1
Dietz, J1
Spooner, JW1
Alexopoulos, GS1
Shamoian, CA1
Razavi, D1
Mendlewicz, J2
Nasrallah, HA1
Lyskowksi, J1
Schroeder, D1
Schaffer, CB1
Mulder, RT1
Joyce, PR1
Dilsaver, SC2
Swann, AC1
Sachs, GS1
Lafer, B1
Stoll, AL1
Banov, M1
Thibault, AB1
Tohen, M1
Rosenbaum, JF1
Black, KJ1
Kilzieh, N1
Piletz, JE1
DeMet, E1
Gwirtsman, HE1
Halaris, A1
Zaphiris, HA1
Blaisdell, GD1
Jermain, DM1
Bloch, M1
Schwartzman, Y1
Bonne, O1
Lerer, B1
Landry, P1
Roy, L1
Morishita, S1
Aoki, S1
Watanabe, S1
Tallman, J1
Smith, CC1
Claeys, MM1
Markey, SP1
Wehr, TA2
Glassman, AH1
Perel, JM1
Shostak, M1
Kantor, SJ1
Fleiss, JL1
Coupland, N1
Glue, P1
Santos, AB1
Ballenger, JC2
Dinan, TG2
Yatham, LN1
O'Keane, V1
Barry, S2
Rudorfer, MV2
Sherer, MA1
Lane, EA2
Golden, RN2
Delgado, PL1
Scheinin, M1
Cowdry, RW1
Calil, HM1
Ross, RJ1
Campbell, SS1
Gillin, JC1
Kripke, DF1
Janowsky, DS1
Risch, SC1
Brady, KT1
Pandey, GN1
Janicak, PG1
Javaid, JI1
Davis, JM1
Rush, AJ1
Giles, DE1
Jarrett, RB1
Feldman-Koffler, F1
Debus, JR1
Weissenburger, J1
Orsulak, PJ1
Roffwarg, HP1
Rubinow, DR1
Gold, PW1
Guthrie, S1
Rudorfer, M1
Bovier, P1
Widmer, J1
Gaillard, JM1
Tissot, R1
Hanin, I1
Koslow, SH1
Kocsis, JH1
Bowden, CL1
Brunswick, D1
Frazer, A1
Carl, J1
Robins, E1
Schweizer, E1
Dever, A1
Clary, C1
Esche, I1
Joffe, RT1
Blank, DW1
Thienhaus, OJ1
Vogel, N1
Corral, M1
Sivertz, K1
Jones, BD1
Stewart, JW1
McGrath, PJ1
Harrison, W1
Quitkin, F1
Rabkin, JG1
Gambini, O1
Maggioni, M1
Baer, L1
Minichiello, WE1
Jenike, MA1
Arana, GW1
Kaplan, GB1
Meesters, P1
Kerkhofs, M1
Charles, G1
Decoster, C1
Vanderelst, M1
Opitz, K1
Chu, H1
Schildkraut, JJ1
Schanberg, SM1
Breese, GR1
Kopin, IJ1
Ogura, C1
Okuma, T1
Uchida, Y1
Imai, S1
Yogi, H1
Mendels, J1
Secunda, SK1
Dyson, WL1
Dekirmenjian, H1
Fawcett, JA1
Furlong, FW2
Luby, ED2
Vestre, ND1
Janecek, J1
Zimmermann, R1
Kammerer, M1
Wartel, R1
Gurfein, L1
Weil, J1
Wysoki, V1
Gelb, F1
Rodová, A1
Svestka, J1
Náhunek, K1
dos Reis, MA1
Wolpowitz, B1
Roux, JT1
McLaughlin, BE1
Margat, P1
Broussot, T1
Pouly, JP1
Hendrie, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Acute Efficacy of Bupropion, Sertraline, and Venlafaxine as Adjuvant Treatment to Mood Stabilizers in Bipolar Depression: A Randomized, Double-Blind, Comparative Study[NCT00001483]Phase 275 participants Interventional1995-06-30Completed
Cerebral Neuroinflammation During Major Depressive Episode: Multicentric Comparative Study.[NCT03314155]60 participants (Anticipated)Interventional2018-12-07Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for desipramine and Affective Psychosis, Bipolar

ArticleYear
Noradrenergic function and depression, too much or too little?
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1980, Volume: 7, Issue:3

    Topics: Amphetamine; Bipolar Disorder; Brain; Brain Chemistry; Desipramine; Electroconvulsive Therapy; Human

1980
Newer uses for older psychotropic medications.
    Hospital & community psychiatry, 1982, Volume: 33, Issue:4

    Topics: Adrenergic beta-Antagonists; Agoraphobia; Anxiety Disorders; Bipolar Disorder; Clonidine; Depressive

1982
Psychopharmacologic treatment of depression.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:3

    Topics: Affective Disorders, Psychotic; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychot

1984
Pharmacologic induction of cholinergic system up-regulation and supersensitivity in affective disorders research.
    Journal of clinical psychopharmacology, 1986, Volume: 6, Issue:2

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain; Depressio

1986
MHPG excretion by patients with affective disorders.
    International pharmacopsychiatry, 1974, Volume: 9, Issue:1

    Topics: Affective Symptoms; Bipolar Disorder; Brain; Catecholamines; Creatinine; Depression; Desipramine; De

1974

Trials

20 trials available for desipramine and Affective Psychosis, Bipolar

ArticleYear
A double-blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression. I. Clinical findings.
    Acta psychiatrica Scandinavica, 1982, Volume: 66, Issue:1

    Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Brompheniramine; Depressive Disorder; Desipram

1982
Comparison between zimelidine and desipramine in endogenous depression. A cross-over study.
    Acta psychiatrica Scandinavica, 1982, Volume: 66, Issue:2

    Topics: Antidepressive Agents; Bipolar Disorder; Brompheniramine; Depressive Disorder; Desipramine; Double-B

1982
Effects of antidepressant treatments on dopamine turnover in depressed patients.
    Archives of general psychiatry, 1983, Volume: 40, Issue:9

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Antidepressive Agents; Bipolar Disorder; Brompheniramine; Clo

1983
Relationships of the Tridimensional Personality Questionnaire to mood and personality measures for depressed patients.
    Psychological reports, 1994, Volume: 75, Issue:3 Pt 1

    Topics: Adolescent; Adult; Affect; Bipolar Disorder; Clomipramine; Depressive Disorder; Desipramine; Female;

1994
A double-blind trial of bupropion versus desipramine for bipolar depression.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:9

    Topics: Adult; Anticonvulsants; Bipolar Disorder; Bupropion; Desipramine; Double-Blind Method; Drug Therapy,

1994
Concurrent treatment of nonresistant major depression with desipramine and lithium: a double-blind, placebo-controlled study.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:1

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Desipramine; D

1997
Different effect of desipramine on protein kinase C in platelets between bipolar and major depressive disorders.
    Psychiatry and clinical neurosciences, 1999, Volume: 53, Issue:1

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Blood Platelets; Depressive Disorde

1999
Changes in lymphocyte beta-adrenergic receptors in depression and mania.
    Psychiatry research, 1979, Volume: 1, Issue:2

    Topics: Adult; Bipolar Disorder; Clinical Trials as Topic; Cyclic AMP; Depressive Disorder; Desipramine; Dih

1979
Imipramine and desipramine in plasma and spinal fluid: relationship to clinical response and serotonin metabolism.
    Archives of general psychiatry, 1978, Volume: 35, Issue:5

    Topics: Adult; Bipolar Disorder; Brain; Clinical Trials as Topic; Depression; Desipramine; Double-Blind Meth

1978
Rapid cycling in manic-depressives induced by tricyclic antidepressants.
    Archives of general psychiatry, 1979, Volume: 36, Issue:5

    Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Bipolar Disorder; Circadian Rhythm; Desipramine

1979
Acute noradrenergic effects of desipramine in depression.
    Journal of clinical psychopharmacology, 1991, Volume: 11, Issue:1

    Topics: Administration, Oral; Adult; Aged; Bipolar Disorder; Blood Pressure; Depressive Disorder; Desipramin

1991
Fenfluramine augmentation in tricyclic-refractory depression.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:5

    Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female;

1990
Selective antidepressants and cerebrospinal fluid. Lack of specificity on norepinephrine and serotonin metabolites.
    Archives of general psychiatry, 1985, Volume: 42, Issue:12

    Topics: Adolescent; Adult; Aged; Bipolar Disorder; Clorgyline; Depressive Disorder; Desipramine; Female; Gly

1985
Reduced REM latency predicts response to tricyclic medication in depressed outpatients.
    Biological psychiatry, 1989, Volume: 26, Issue:1

    Topics: Adolescent; Adult; Aged; Amitriptyline; Bipolar Disorder; Clinical Trials as Topic; Depressive Disor

1989
Treatment outcome validation of DSM-III depressive subtypes. Clinical usefulness in outpatients with mild to moderate depression.
    Archives of general psychiatry, 1985, Volume: 42, Issue:12

    Topics: Anxiety Disorders; Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; Desipramine; Dou

1985
A controlled study of the antidepressant effects of lithium carbonate.
    Archives of general psychiatry, 1972, Volume: 26, Issue:2

    Topics: Adult; Age Factors; Analysis of Variance; Bipolar Disorder; Carbonates; Clinical Trials as Topic; De

1972
Lithium in the control of mania.
    International journal of neuropsychiatry, 1967, Volume: 3, Issue:4

    Topics: Adult; Amitriptyline; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Desipramine; Femal

1967
A controlled study of desipramine in the treatment of hospitalized depressive disorders.
    International journal of neuropsychiatry, 1967, Volume: 3, Issue:4

    Topics: Adolescent; Adult; Aged; Bipolar Disorder; Clinical Trials as Topic; Depression; Desipramine; Female

1967
[Clinical experimentation with desipramine with statistical control].
    Annales medico-psychologiques, 1968, Volume: 1, Issue:1

    Topics: Adult; Aged; Anorexia Nervosa; Barbiturates; Bipolar Disorder; Chlordiazepoxide; Chlorpromazine; Cli

1968
[Clinical experience with desipramine in endogenous and involutional depressions].
    Activitas nervosa superior, 1970, Jan-12, Volume: 12, Issue:1

    Topics: Adult; Aged; Bipolar Disorder; Clinical Trials as Topic; Depression; Depressive Disorder, Major; Des

1970

Other Studies

60 other studies available for desipramine and Affective Psychosis, Bipolar

ArticleYear
[ENDOGENOUS DEPRESSIONS TREATED WITH PERTOFRANE].
    Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry, 1963, Volume: 17

    Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Psychotic Disorde

1963
[ON THE METHODOLOGY OF RESEARCH ON ANTIDEPRESSIVE DRUGS WITH SPECIAL REFERENCE TO IMIPRAMINE (TOFRANIL) AND DESMETHYLIMIPRAMINE (PERTOFRAN)].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1963, Sep-18, Volume: 204

    Topics: Aging; Antidepressive Agents; Bipolar Disorder; Body Constitution; Desipramine; Humans; Imipramine;

1963
[RESULTS OF THE USE OF DESMETHYL-IMIPRAMINE (G-35020, PERTOFRAN) IN THE DEPRESSIVE SYNDROME].
    Wiener medizinische Wochenschrift (1946), 1963, Dec-07, Volume: 113

    Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Imipramine; Menta

1963
[DESMETHYLIMIPRAMINE (PERTOFRAN) IN THE TREATMENT OF DEPRESSIONS. A CLINICAL AND PSYCHODYNAMIC APPRAISAL].
    Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry, 1963, Volume: 17

    Topics: Antidepressive Agents; Biomedical Research; Bipolar Disorder; Chlorpromazine; Depression; Depressive

1963
[DESIPRAMINE (PERTOFRAN) IN THE TREATMENT OF DEPRESSIONS WITH A PSYCHODYNAMIC ANALYSIS OF ITS THERAPEUTIC EFFECTS].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1964, Mar-16, Volume: 205

    Topics: Antidepressive Agents; Biomedical Research; Bipolar Disorder; Depression; Depressive Disorder; Desip

1964
[ACTION OF DESMETHYL-IMIPRAMINE (PERTOFRAN) IN DEPRESSIVE SYNDROMES].
    Acta neurologica et psychiatrica Belgica, 1964, Volume: 64

    Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Imipramine; Neuro

1964
CLINICAL TRIAL OF A NEW ANTIDEPRESSANT (DESIPRAMINE HYDROCHLORIDE) IN A HOSPITAL SETTING.
    The American journal of psychiatry, 1965, Volume: 121

    Topics: Antidepressive Agents; Biomedical Research; Bipolar Disorder; Depression; Depressive Disorder; Desip

1965
Opioid plasma levels in primary affective disorders. Effect of desimipramine therapy.
    Neuropsychobiology, 1984, Volume: 12, Issue:2-3

    Topics: Adrenocorticotropic Hormone; Adult; Affective Disorders, Psychotic; Aged; beta-Endorphin; beta-Lipot

1984
Amoxapine elevates serum prolactin in depressed men.
    Journal of affective disorders, 1983, Volume: 5, Issue:4

    Topics: Amoxapine; Bipolar Disorder; Depressive Disorder; Desipramine; Dibenzoxazepines; Humans; Male; Middl

1983
Identifying depression secondary to lithium-induced hypothyroidism.
    Psychosomatics, 1984, Volume: 25, Issue:11

    Topics: Bipolar Disorder; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Therapy,

1984
Manic symptoms following addition of lithium to antidepressant treatment.
    Journal of clinical psychopharmacology, 1984, Volume: 4, Issue:6

    Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Drug Thera

1984
Use of an MMPI scale to predict antidepressant response to lithium.
    Psychiatry research, 1983, Volume: 10, Issue:1

    Topics: Adult; Amitriptyline; Bipolar Disorder; Depressive Disorder; Desipramine; Female; Humans; Lithium; M

1983
Facial EMG activity levels predict treatment outcome in depression.
    Psychiatry research, 1984, Volume: 13, Issue:4

    Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Electromyo

1984
Urinary 3-methoxy-4-hydroxyphenylglycol and major affective disorders. A replication and new findings.
    Archives of general psychiatry, 1984, Volume: 41, Issue:4

    Topics: Adult; Bipolar Disorder; Circadian Rhythm; Depressive Disorder; Desipramine; Female; Glycols; Humans

1984
Massive eosinophilic reaction to desipramine in conjunction with pneumonia.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1984, Volume: 29, Issue:2

    Topics: Aged; Amitriptyline; Bipolar Disorder; Desipramine; Dexamethasone; Eosinophilia; Female; Humans; Hyd

1984
Carbamazepine and desipramine: a toxic reaction.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:8

    Topics: Adult; Bipolar Disorder; Carbamazepine; Desipramine; Drug Interactions; Female; Humans

1984
Therapeutic use of the tricyclic-induced switch in bipolar manic-depression.
    The American journal of psychiatry, 1982, Volume: 139, Issue:2

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Desipramine; Drug Therapy,

1982
Does subclinical hypothyroidism predispose to tricyclic-induced rapid mood cycles?
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:7

    Topics: Adult; Bipolar Disorder; Depressive Disorder; Desipramine; Female; Humans; Hypothyroidism; Lithium;

1982
Abnormal anterior pituitary responsiveness to hypothalamic hormones in primary affective disorders. Effect of desipramine therapy.
    Neuropsychobiology, 1982, Volume: 8, Issue:5

    Topics: Adult; Affective Disorders, Psychotic; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Fem

1982
Hypomania after desipramine withdrawal.
    The American journal of psychiatry, 1983, Volume: 140, Issue:5

    Topics: Adolescent; Affective Disorders, Psychotic; Bipolar Disorder; Depressive Disorder; Desipramine; Huma

1983
Potentiation of antidepressant effects by L-triiodothyronine in tricyclic nonresponders.
    The American journal of psychiatry, 1982, Volume: 139, Issue:1

    Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Dis

1982
Myoclonus and ocular oscillations induced by L-tryptophan.
    Annals of neurology, 1982, Volume: 11, Issue:1

    Topics: Adult; Bipolar Disorder; Desipramine; Drug Therapy, Combination; Eye Movements; Female; Humans; Myoc

1982
Tricyclic antidepressants and cardiac patients with pacemakers.
    The American journal of psychiatry, 1982, Volume: 139, Issue:4

    Topics: Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Desipramine; Female;

1982
Tricyclic antidepressant plasma levels: the state of the art and clinical prospects.
    Neuropsychobiology, 1982, Volume: 8, Issue:2

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biotransformation; Bipolar Disorder; Depressive Dis

1982
TCA-induced mania: differences between switchers and nonswitchers.
    Biological psychiatry, 1982, Volume: 17, Issue:2

    Topics: Adult; Affective Disorders, Psychotic; Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic;

1982
DST during drug-induced switch from depression to mania.
    The American journal of psychiatry, 1982, Volume: 139, Issue:8

    Topics: Bipolar Disorder; Depressive Disorder; Desipramine; Dexamethasone; Female; Humans; Hydrocortisone; L

1982
Mixed mania: apparent induction by a tricyclic antidepressant in five consecutively treated patients with bipolar depression.
    Biological psychiatry, 1995, Jan-01, Volume: 37, Issue:1

    Topics: Adult; Bipolar Disorder; Desipramine; Female; Humans; Male; Middle Aged; Nortriptyline

1995
Severe imipramine-induced myoclonus in a patient with psychotic bipolar depression, catatonia, and schizencephaly.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1994, Volume: 6, Issue:1

    Topics: Adult; Bipolar Disorder; Catatonia; Desipramine; Dose-Response Relationship, Drug; Drug Therapy, Com

1994
Disruption of circadian MHPG rhythmicity in major depression.
    Biological psychiatry, 1994, Jun-01, Volume: 35, Issue:11

    Topics: Adult; Bipolar Disorder; Circadian Rhythm; Depressive Disorder; Desipramine; Female; Humans; Male; M

1994
Probable nefazodone-induced mania in a patient with unreported bipolar disorder.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1996, Volume: 8, Issue:4

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depres

1996
Withdrawal hypomania associated with paroxetine.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bipolar Disorder;

1997
Rapid mood cycles after a noradrenergic but not a serotonergic antidepressant.
    The American journal of psychiatry, 1979, Volume: 136, Issue:12

    Topics: Allylamine; Antidepressive Agents; Bipolar Disorder; Brain; Desipramine; Female; Humans; Middle Aged

1979
Clinical implications of imipramine plasma levels for depressive illness.
    Archives of general psychiatry, 1977, Volume: 34, Issue:2

    Topics: Bipolar Disorder; Delusions; Depression; Desipramine; Dose-Response Relationship, Drug; Female; Huma

1977
Blunting growth hormone release in mania.
    The American journal of psychiatry, 1992, Volume: 149, Issue:9

    Topics: Bipolar Disorder; Clonidine; Desipramine; Growth Hormone; Humans; Receptors, Adrenergic, alpha

1992
Tricyclic antidepressant triggers mania in patient with organic affective disorder.
    The Journal of clinical psychiatry, 1992, Volume: 53, Issue:10

    Topics: Adult; Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain Injuries; Depressive Disorder; Desi

1992
Blunting of noradrenergic-stimulated growth hormone release in mania.
    The American journal of psychiatry, 1991, Volume: 148, Issue:7

    Topics: Adolescent; Adult; Aged; Bipolar Disorder; Desipramine; Down-Regulation; Female; Growth Hormone; Hum

1991
Responses of growth hormone to desipramine in endogenous and non-endogenous depression.
    The British journal of psychiatry : the journal of mental science, 1990, Volume: 156

    Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Dexamethasone; Diagnosis, Different

1990
Lithium delays circadian phase of temperature and REM sleep in a bipolar depressive: a case report.
    Psychiatry research, 1989, Volume: 27, Issue:1

    Topics: Bipolar Disorder; Body Temperature Regulation; Circadian Rhythm; Desipramine; Drug Therapy, Combinat

1989
The thyroid axis and desipramine treatment in depression.
    Biological psychiatry, 1989, Mar-15, Volume: 25, Issue:6

    Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Male; Middle Aged; Psycholo

1989
Increased 3H-clonidine binding in the platelets of patients with depressive and schizophrenic disorders.
    Psychiatry research, 1989, Volume: 28, Issue:1

    Topics: Bipolar Disorder; Blood Platelets; Clonidine; Depressive Disorder; Desipramine; Humans; Imidazoline

1989
CSF somatostatin in affective illness and normal volunteers.
    Progress in neuro-psychopharmacology & biological psychiatry, 1985, Volume: 9, Issue:4

    Topics: Bipolar Disorder; Carbamazepine; Depressive Disorder; Desipramine; Humans; Imipramine; Lithium; Lith

1985
Clinical studies on norepinephrine metabolism: how to interpret the numbers.
    Psychiatry research, 1986, Volume: 17, Issue:3

    Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Female; Glycols; Humans; Kinetics;

1986
Evolution of red blood cell membrane transport and plasma level of L-tyrosine and L-tryptophan in depressed treated patients according to clinical improvement.
    Neuropsychobiology, 1988, Volume: 19, Issue:3

    Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Erythrocyte

1988
Cerebrospinal fluid levels of amitriptyline, nortriptyline, imipramine and desmethylimipramine. Relationship to plasma levels and treatment outcome.
    Journal of affective disorders, 1985, Volume: 9, Issue:1

    Topics: Amitriptyline; Bipolar Disorder; Depressive Disorder; Desipramine; Double-Blind Method; Female; Gas

1985
Suicide upon recovery from depression. A clinical note.
    The Journal of nervous and mental disease, 1988, Volume: 176, Issue:10

    Topics: Adult; Bipolar Disorder; Depressive Disorder; Desipramine; Electroconvulsive Therapy; Female; Humans

1988
Erythrocyte electrolytes in psychiatric illness.
    Acta psychiatrica Scandinavica, 1988, Volume: 78, Issue:6

    Topics: Adult; Bipolar Disorder; Depressive Disorder; Desipramine; Erythrocytes; Female; Humans; Male; Menta

1988
Desipramine and testicular swelling in two patients.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:1

    Topics: Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Male; Middle Aged; Pain; Testicular Dise

1988
Transient mood elevation associated with antidepressant drug decrease.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1987, Volume: 32, Issue:9

    Topics: Bipolar Disorder; Depressive Disorder; Desipramine; Emotions; Female; Humans; Middle Aged; Substance

1987
Abnormal anterior pituitary responsiveness to hypothalamic hormones in depression: neurophysiological correlates and psychopharmacological effects.
    Advances in biochemical psychopharmacology, 1985, Volume: 40

    Topics: Adult; Aged; Bipolar Disorder; Clomipramine; Depressive Disorder; Desipramine; Female; Gonadotropin-

1985
Behavioral treatment in two cases of obsessive-compulsive disorder with concomitant bipolar affective disorder.
    The American journal of psychiatry, 1985, Volume: 142, Issue:3

    Topics: Adult; Behavior Therapy; Bipolar Disorder; Desipramine; Female; Haloperidol; Humans; Lithium; Male;

1985
Trazodone-induced mania following desipramine-induced mania in major depressive disorders.
    The American journal of psychiatry, 1985, Volume: 142, Issue:3

    Topics: Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged; Piperaz

1985
Growth hormone release after desipramine in depressive illness.
    European archives of psychiatry and neurological sciences, 1985, Volume: 235, Issue:3

    Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Female; Growth Hormone; Humans; Mal

1985
[Effect of lithium on the respiratory metabolism of rats and calorigenic effects of sympathomimetic amines].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 266, Issue:4

    Topics: Animals; Bipolar Disorder; Depression, Chemical; Desipramine; Drug Synergism; Humans; Lithium; Norep

1970
Norepinephrine metabolism and drugs used in the affective disorders: a possible mechanism of action.
    The American journal of psychiatry, 1967, Volume: 124, Issue:5

    Topics: Animals; Antidepressive Agents; Bipolar Disorder; Brain; Central Nervous System Stimulants; Chlorpro

1967
Combined thyroid (triiodothyronine)-tricyclic antidepressant treatment in depressive states.
    Folia psychiatrica et neurologica japonica, 1974, Volume: 28, Issue:3

    Topics: Adjustment Disorders; Adult; Amitriptyline; Antidepressive Agents; Anxiety; Bipolar Disorder; Blood

1974
[Desipramine in the treatment of depressions in ambulatory care and hospital care].
    Hospital (Rio de Janeiro, Brazil), 1966, Volume: 69, Issue:5

    Topics: Bipolar Disorder; Depression; Desipramine; Humans

1966
[Parenteral treatment of depressive diseases].
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1970, Oct-10, Volume: 44, Issue:40

    Topics: Antidepressive Agents; Bipolar Disorder; Dementia; Depression; Depressive Disorder, Major; Desiprami

1970
Unexpected failure of a satisfactory anti-depressive drug routine to control hostile expression in psychiatric out-patients.
    Diseases of the nervous system, 1970, Volume: 31

    Topics: Adjustment Disorders; Ambulatory Care; Antidepressive Agents; Anxiety; Bipolar Disorder; Chlordiazep

1970
[Trial of G. 35020 in 52 cases of depression].
    Annales medico-psychologiques, 1968, Volume: 1, Issue:1

    Topics: Adult; Aged; Bipolar Disorder; Depression; Depressive Disorder, Major; Desipramine; Female; Humans;

1968
A two-year clinical experience with lithium.
    Canadian Psychiatric Association journal, 1968, Volume: 13, Issue:6

    Topics: Adult; Bipolar Disorder; Desipramine; Female; Follow-Up Studies; Haloperidol; Humans; Lithium; Male;

1968