desipramine has been researched along with Affective Disorders, Psychotic in 16 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Affective Disorders, Psychotic: Disorders in which the essential feature is a severe disturbance in mood (depression, anxiety, elation, and excitement) accompanied by psychotic symptoms such as delusions, hallucinations, gross impairment in reality testing, etc.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Imipramine doses were adjusted to attain a predefined fixed plasma level." | 1.35 | Efficacy of imipramine in psychotic versus nonpsychotic depression. ( Birkenhager, TK; Bruijn, JA; Moleman, P; Mulder, PG; van den Broek, WW, 2008) |
| "Desipramine was given at a dose of 50-100 mg/day for 3-5 weeks." | 1.26 | Abnormal anterior pituitary responsiveness to hypothalamic hormones in primary affective disorders. Effect of desipramine therapy. ( Brambilla, F; Massironi, R; Nobile, P; Pugnetti, L; Scarone, S, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (87.50) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Birkenhager, TK | 1 |
| van den Broek, WW | 1 |
| Mulder, PG | 1 |
| Moleman, P | 1 |
| Bruijn, JA | 1 |
| Genazzani, AR | 1 |
| Petraglia, F | 1 |
| Facchinetti, F | 1 |
| Monittola, C | 1 |
| Scarone, S | 2 |
| Brambilla, F | 3 |
| Nelson, JC | 2 |
| Jatlow, PI | 1 |
| Extein, I | 3 |
| Gold, MS | 1 |
| Pottash, AL | 1 |
| Potter, WZ | 4 |
| Karoum, F | 1 |
| Linnoila, M | 2 |
| Calil, HM | 2 |
| Gold, PW | 1 |
| Wehr, TA | 2 |
| Goodwin, FK | 2 |
| Massironi, R | 1 |
| Nobile, P | 1 |
| Pugnetti, L | 1 |
| Schottenfeld, RS | 1 |
| Conrad, CD | 2 |
| Brown, RP | 1 |
| Sweeney, J | 1 |
| Frances, A | 1 |
| Kocsis, JH | 1 |
| Loutsch, E | 1 |
| Gold, P | 1 |
| Nasrallah, HA | 1 |
| Lyskowksi, J | 1 |
| Schroeder, D | 1 |
| Low, G | 1 |
| Zavadil, AP | 1 |
| Davidson, JR | 1 |
| McLeod, MN | 1 |
| Kurland, AA | 1 |
| White, HL | 1 |
| Kudler, HS | 1 |
| Cavagnini, F | 1 |
| Invitti, C | 1 |
| Poterzio, F | 1 |
| Lampertico, M | 1 |
| Sali, L | 1 |
| Maggioni, M | 1 |
| Candolfi, C | 1 |
| Panerai, AE | 1 |
| Müller, EE | 1 |
1 review available for desipramine and Affective Disorders, Psychotic
| Article | Year |
|---|---|
Psychopharmacologic treatment of depression.
Topics: Affective Disorders, Psychotic; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychot | 1984 |
2 trials available for desipramine and Affective Disorders, Psychotic
| Article | Year |
|---|---|
Comparative pharmacokinetics of zimelidine and desipramine in man following acute and chronic administration.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Antidepressive Agents; Brompheniramine; Des | 1979 |
Antidepressant drug therapy in psychotic depression.
Topics: Adult; Affective Disorders, Psychotic; Clinical Trials as Topic; Delusions; Desipramine; Double-Blin | 1977 |
13 other studies available for desipramine and Affective Disorders, Psychotic
| Article | Year |
|---|---|
Efficacy of imipramine in psychotic versus nonpsychotic depression.
Topics: Adult; Affective Disorders, Psychotic; Aged; Antidepressive Agents; Data Interpretation, Statistical | 2008 |
Opioid plasma levels in primary affective disorders. Effect of desimipramine therapy.
Topics: Adrenocorticotropic Hormone; Adult; Affective Disorders, Psychotic; Aged; beta-Endorphin; beta-Lipot | 1984 |
Neuroloeptic effect on desipramine steady-state plasma concentratins.
Topics: Adult; Affective Disorders, Psychotic; Antipsychotic Agents; Desipramine; Drug Therapy, Combination; | 1980 |
Common mechanism of action of biochemically "specific" antidepressants.
Topics: Adult; Affective Disorders, Psychotic; Antidepressive Agents; Clorgyline; Desipramine; Female; Human | 1984 |
Specific norepinephrine and serotonin uptake inhibitors in man: a crossover study with pharmacokinetic, biochemical, neuroendocrine and behavioral parameters.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Behavior; Brompheniramine; Desipramine; Dou | 1981 |
Abnormal anterior pituitary responsiveness to hypothalamic hormones in primary affective disorders. Effect of desipramine therapy.
Topics: Adult; Affective Disorders, Psychotic; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Fem | 1982 |
Hypomania after desipramine withdrawal.
Topics: Adolescent; Affective Disorders, Psychotic; Bipolar Disorder; Depressive Disorder; Desipramine; Huma | 1983 |
Age as a predictor of treatment response in endogenous depression.
Topics: Adult; Affective Disorders, Psychotic; Age Factors; Aged; Amitriptyline; Antidepressive Agents, Tric | 1983 |
Tricyclic antidepressants do not alter thyroid hormone levels in patients suffering from a major affective disorder.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Amitriptyline; Antidepressive Agents, Tricy | 1981 |
TCA-induced mania: differences between switchers and nonswitchers.
Topics: Adult; Affective Disorders, Psychotic; Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic; | 1982 |
New classes of antidepressants that may be lethal in combination.
Topics: Adult; Affective Disorders, Psychotic; Depressive Disorder; Desipramine; Dose-Response Relationship, | 1995 |
Symptom exacerbation in psychotically depressed adolescents due to high desipramine plasma concentrations.
Topics: Adolescent; Affective Disorders, Psychotic; Antipsychotic Agents; Desipramine; Drug Interactions; Dr | 1986 |
Neuroendocrine and psychopathological measures in anorexia nervosa: resemblances to primary affective disorders.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Anorexia Nervosa; beta-Endorphin; beta-Lipotropin | 1985 |