desipramine has been researched along with Acute Disease in 10 studies
Desipramine: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
desipramine : A dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The degree of anorexia and plasma corticosterone elevation in response to the stress was measured." | 3.67 | The effect of acute and chronic administration of desmethylimipramine on responses to stress in rats. ( Platt, JE; Stone, EA; Trullas, R, 1984) |
| " We present a case of significant behavioral side effects in a young woman secondary to elevated plasma levels of imipramine and desipramine, masquerading as an agitated psychotic depression." | 3.67 | Profound behavioral toxicity due to tricyclic antidepressants. ( Grunhaus, L; Meador-Woodruff, JH, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Levkovitz, Y | 1 |
| Caftori, R | 1 |
| Avital, A | 1 |
| Richter-Levin, G | 1 |
| Thangathurai, D | 1 |
| Roffey, P | 1 |
| Mogos, M | 1 |
| Riad, M | 1 |
| Mikhail, M | 1 |
| Basile, AS | 1 |
| Janowsky, A | 1 |
| Golembiowska, K | 1 |
| Kowalska, M | 1 |
| Tam, E | 1 |
| Benveniste, M | 1 |
| Popik, P | 1 |
| Nikiforuk, A | 1 |
| Krawczyk, M | 1 |
| Nowak, G | 1 |
| Krieter, PA | 1 |
| Lippa, AS | 1 |
| Skolnick, P | 1 |
| Koustova, E | 1 |
| Stone, EA | 1 |
| Trullas, R | 1 |
| Platt, JE | 1 |
| Sawyer, WT | 1 |
| Caudill, JL | 1 |
| Ellison, MJ | 1 |
| Detke, MJ | 1 |
| Johnson, J | 1 |
| Lucki, I | 1 |
| Cao, L | 1 |
| Filipov, NM | 1 |
| Lawrence, DA | 1 |
| Peselow, ED | 1 |
| Fieve, RR | 1 |
| DiFiglia, C | 1 |
| Tribble, J | 1 |
| Weinhouse, E | 1 |
| Garland, J | 1 |
| Wendelberger, K | 1 |
| Meador-Woodruff, JH | 1 |
| Grunhaus, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy Of Switching From SSRI to Desvenlafaxine on Cognitive Function In Patients With an Acute Episode of Major Depression[NCT03432221] | 36 participants (Anticipated) | Observational | 2018-04-03 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for desipramine and Acute Disease
| Article | Year |
|---|---|
The SSRIs drug Fluoxetine, but not the noradrenergic tricyclic drug Desipramine, improves memory performance during acute major depression.
Topics: Acute Disease; Adult; Analysis of Variance; Antidepressive Agents, Tricyclic; Depressive Disorder, M | 2002 |
Personality traits and response to desipramine.
Topics: Acute Disease; Adolescent; Adult; Aged; Depressive Disorder; Desipramine; Double-Blind Method; Femal | 1992 |
8 other studies available for desipramine and Acute Disease
| Article | Year |
|---|---|
Usefulness of desipramine in ICU cancer patients for acute depression.
Topics: Acute Disease; Antidepressive Agents, Tricyclic; Critical Care; Depressive Disorder; Desipramine; Hu | 2004 |
Characterization of the antinociceptive actions of bicifadine in models of acute, persistent, and chronic pain.
Topics: Acute Disease; Analgesics; Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Chronic Disease; | 2007 |
The effect of acute and chronic administration of desmethylimipramine on responses to stress in rats.
Topics: Acute Disease; Animals; Anorexia; Chronic Disease; Corticosterone; Depression; Desipramine; Electros | 1984 |
A case of severe acute desipramine overdose.
Topics: Acute Disease; Adult; Bradycardia; Desipramine; Humans; Male; Respiratory Insufficiency; Seizures; S | 1984 |
Acute and chronic antidepressant drug treatment in the rat forced swimming test model of depression.
Topics: Acute Disease; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepress | 1997 |
Sympathetic nervous system plays a major role in acute cold/restraint stress inhibition of host resistance to Listeria monocytogenes.
Topics: Acute Disease; Animals; Cold Temperature; Corticosterone; Desipramine; Enzyme Inhibitors; Immunity, | 2002 |
Treatment of severe imipramine poisoning complicated by a negative history of drug ingestion.
Topics: Acute Disease; Desipramine; Electrocardiography; Emergencies; Female; Gastric Lavage; Humans; Imipra | 1989 |
Profound behavioral toxicity due to tricyclic antidepressants.
Topics: Acute Disease; Adult; Age Factors; Depression; Desipramine; Female; Hospitalization; Humans; Imipram | 1986 |