Page last updated: 2024-08-26

desethylchloroquine and Infections, Plasmodium

desethylchloroquine has been researched along with Infections, Plasmodium in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199014 (73.68)18.7374
1990's3 (15.79)18.2507
2000's0 (0.00)29.6817
2010's1 (5.26)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Baud, FJ; Clemessy, JL; Hoglund, RM; Megarbane, B; Tarning, J; Watson, JA; White, NJ1
Flexner, C; Ippolito, MM; Jacobson, JM; Lederman, MM; Shapiro, TA; Tarning, J; Winterberg, M1
Bergqvist, Y; Domeij-Nyberg, B; Frisk-Holmberg, M; Termond, E1
Adeyokunnu, AA; Alvan, G; Dawodu, AH; Salako, LA; Walker, O1
Blayo, MC; Clavier, F; Deloron, P; Verdier, F1
Churchill, FC; Mount, DL; Schwartz, IK1
Costa, A; Eggelte, TA; Rosário, VE; Seixas, E; Vigário, AM1
Alván, G; Hellgren, U; Jerling, M1
Frisk, M; Gunnert, G1
Ajayi, FO; Kuye, JO; Salako, LA2
Davis, DR; Hutton, DC; Rieckmann, KH1
Björkman, A; Eriksson, O; Hellgren, U; Kihamia, CM; Mahikwano, LF; Rombo, L1
Berry, C; Brown, J; Churchill, FC; Greenwood, BM; Miller, KD; White, NJ; Williams, SB1
Björkman, A; Ericsson, O; Rombo, L; Sego, E1
Bergqvist, Y; Hellgren, U; Rombo, L1
Campbell, CC; Heymann, DL; Khoromana, CO; Wirima, JJ1
Ericsson, O; Kihamia, CM; Mahikwano, LF; Rombo, L; Sjöqvist, F1
Alván, G; Grahnén, A; Gustafsson, LL; Lindström, B1

Trials

1 trial(s) available for desethylchloroquine and Infections, Plasmodium

ArticleYear
Effect of Antiretroviral Therapy on Plasma Concentrations of Chloroquine and Desethyl-chloroquine.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018, 10-30, Volume: 67, Issue:10

    Topics: Adult; Alkynes; Anti-Retroviral Agents; Antimalarials; Antiretroviral Therapy, Highly Active; Benzoxazines; Chloroquine; Cyclopropanes; Drug Interactions; Female; HIV Infections; Humans; Malaria; Male; Middle Aged; Protease Inhibitors

2018

Other Studies

18 other study(ies) available for desethylchloroquine and Infections, Plasmodium

ArticleYear
Concentration-dependent mortality of chloroquine in overdose.
    eLife, 2020, 07-08, Volume: 9

    Topics: Adult; Antimalarials; Biotransformation; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Dose-Response Relationship, Drug; Drug Overdose; Drug Repositioning; Electrocardiography; Female; Heart Diseases; Humans; Hydroxychloroquine; Long QT Syndrome; Malaria; Male; Pandemics; Pneumonia, Viral; Randomized Controlled Trials as Topic; Risk Assessment; Suicide; Suicide, Attempted

2020
The single dose kinetics of chloroquine and its major metabolite desethylchloroquine in healthy subjects.
    European journal of clinical pharmacology, 1984, Volume: 26, Issue:4

    Topics: Administration, Oral; Adult; Chloroquine; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Kinetics; Malaria; Male; Rheumatic Diseases

1984
Plasma chloroquine and desethylchloroquine concentrations in children during and after chloroquine treatment for malaria.
    British journal of clinical pharmacology, 1983, Volume: 16, Issue:6

    Topics: Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Infant; Malaria

1983
[Distribution of chloroquine and desethylchloroquine in blood, plasma and erythrocytes of healthy subjects and malaria patients. Assay using HPLC].
    Pathologie-biologie, 1984, Volume: 32, Issue:5

    Topics: Chloroquine; Chromatography, High Pressure Liquid; Erythrocytes; Female; Humans; Malaria; Male; Plasma

1984
Determination of chloroquine and its major metabolite in blood using perfluoroacylation followed by fused-silica capillary gas chromatography with nitrogen-sensitive detection.
    Journal of chromatography, 1983, May-13, Volume: 274

    Topics: Chloroquine; Chromatography, Gas; Drug Resistance, Microbial; Gas Chromatography-Mass Spectrometry; Humans; Malaria; Methods; Time Factors

1983
Investigation of chloroquine intake in Biombo region, Guinea Bissau.
    Applied parasitology, 1994, Volume: 35, Issue:4

    Topics: Animals; Chloroquine; Chromatography, High Pressure Liquid; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Guinea-Bissau; Humans; Malaria; Plasmodium falciparum

1994
On the question of interindividual variations in chloroquine concentrations.
    European journal of clinical pharmacology, 1993, Volume: 45, Issue:4

    Topics: Adult; Child; Chloroquine; Drug Monitoring; Humans; Malaria; Rheumatic Diseases

1993
Chloroquine in malaria. Isn't it time for revision of prophylaxis schedules?
    European journal of clinical pharmacology, 1993, Volume: 44, Issue:3

    Topics: Chloroquine; Clinical Protocols; Drug Administration Schedule; Female; Humans; Malaria; Male; Sweden

1993
Comparison of the partitioning in vitro of chloroquine and its desethyl metabolites between the erythrocytes and plasma of healthy subjects and those with falciparum malaria.
    African journal of medicine and medical sciences, 1989, Volume: 18, Issue:2

    Topics: Adolescent; Adult; Animals; Child; Chloroquine; Erythrocytes; Female; Humans; Kinetics; Malaria; Male; Plasma; Plasmodium falciparum; Time Factors

1989
Plasmodium vivax resistance to chloroquine?
    Lancet (London, England), 1989, Nov-18, Volume: 2, Issue:8673

    Topics: Acute Disease; Animals; Antimalarials; Blood Specimen Collection; Chloroquine; Dapsone; Drug Administration Schedule; Drug Combinations; Drug Evaluation; Drug Resistance; Humans; Malaria; Male; Papua New Guinea; Plasmodium vivax; Pyrimethamine

1989
Response of Plasmodium falciparum to chloroquine treatment: relation to whole blood concentrations of chloroquine and desethylchloroquine.
    Bulletin of the World Health Organization, 1989, Volume: 67, Issue:2

    Topics: Adolescent; Animals; Child; Chloroquine; Humans; Malaria; Plasmodium falciparum

1989
Chloroquine treatment of severe malaria in children. Pharmacokinetics, toxicity, and new dosage recommendations.
    The New England journal of medicine, 1988, Dec-08, Volume: 319, Issue:23

    Topics: Animals; Child; Child, Preschool; Chloroquine; Drug Administration Schedule; Humans; Hypotension; Infant; Infusions, Intravenous; Injections, Intramuscular; Injections, Subcutaneous; Intubation, Gastrointestinal; Malaria; Plasmodium falciparum; Prospective Studies

1988
Whole blood concentrations of chloroquine and desethylchloroquine during and after treatment of adult patients infected with Plasmodium vivax, P. ovale or P. malariae.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1986, Volume: 80, Issue:5

    Topics: Adult; Chloroquine; Female; Humans; Malaria; Male; Middle Aged; Plasmodium malariae; Plasmodium vivax; Time Factors

1986
Antimalarial activity of bisdesethylchloroquine against P. falciparum and P. berghei berghei.
    Annals of tropical medicine and parasitology, 1987, Volume: 81, Issue:4

    Topics: Animals; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum

1987
Chloroquine and desethylchloroquine concentrations during regular long-term malaria prophylaxis.
    Bulletin of the World Health Organization, 1987, Volume: 65, Issue:6

    Topics: Adult; Chloroquine; Chromatography, High Pressure Liquid; Female; Humans; Malaria; Male

1987
In vivo efficacy of chloroquine treatment for Plasmodium falciparum in Malawian children under five years of age.
    The American journal of tropical medicine and hygiene, 1986, Volume: 35, Issue:3

    Topics: Administration, Oral; Child, Preschool; Chloroquine; Drug Evaluation; Humans; Malaria; Malawi; Plasmodium falciparum

1986
Concentrations of chloroquine and desethylchloroquine in capillary blood dried on filter paper during and after treatment of Tanzanian children infected with Plasmodium falciparum.
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1986, Volume: 37, Issue:3

    Topics: Adolescent; Child; Chloroquine; Chromatography, Liquid; Humans; Kinetics; Malaria; Plasmodium falciparum; Tanzania

1986
Chloroquine excretion following malaria prophylaxis.
    British journal of clinical pharmacology, 1987, Volume: 24, Issue:2

    Topics: Adult; Chloroquine; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Malaria; Male

1987