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desethylamiodarone and Arrhythmias, Cardiac

desethylamiodarone has been researched along with Arrhythmias, Cardiac in 39 studies

*Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction. [MeSH]

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199025 (64.10)18.7374
1990's10 (25.64)18.2507
2000's3 (7.69)29.6817
2010's1 (2.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miyakawa, M; Scanlan, TS; Snead, AN; Tan, ES1
Baczkó, I; Falkay, G; Leprán, I; Morvay, N; Papp, JG; Sztojkov-Ivanov, A; Varró, A1
Fukumoto, K; Kamakura, S; Kato, R; Kitakaze, M; Kobayashi, T; Komamura, K; Tachibana, K; Tanaka, K; Ueno, K1
Lüderitz, B; Nitsch, J1
Belhassen, B; Greenspan, AM; Greenspon, AJ; Horowitz, LN; Rotmensch, HH; Shoshani, D; Spielman, SR; Swanson, BN; Vlasses, PH1
Aquili, C; Ferrari, M; Fornaro, G; Fortina, A; Padrini, R; Piovan, D; Rossi, P; Tomassini, G1
Harris, L; Hind, CR; Holt, DW; Krikler, SJ; McKenna, WJ; Savage, C; Storey, GC1
Caplin, JL; Nicholson, AA; Steventon, DM1
Berti, S; Biagini, A; Cazzuola, F; Clerico, A; Iervasi, G; Manfredi, C; Sabatino, L; Turchi, S1
Bory, M; Deharo, JC; Djiane, P; Durand, A; Le Tallec, L; Macaluso, G; Malaterre, H; Panagides, D1
Hagiwara, N; Kasanuki, H; Matsuda, N; Sato, K; Shiga, T; Shoda, M; Wakaumi, M1
de Vijlder, JJ; Plomp, TA; Vulsma, T1
Abdollah, H; Brennan, FJ; Brien, JF2
Abdollah, H; Brennan, FJ; Brien, JF; Jimmo, S1
Funck-Brentano, C; Jacqz-Aigrain, E; Jaillon, P; Leenhardt, A; Poirier, JM; Roux, A1
Bastien, O; Chassard, D; Estanove, S; George, M; Guiraud, M; Hercule, C; Lehot, JJ; Villard, J1
Bandyopadhyay, S; Gross, SA; Klaunig, JE; Somani, P1
Mostow, ND; Noon, D; Rakita, L; Vrobel, TR2
Davies, M; Nattel, S; Quantz, M1
Hearse, DJ; Riva, E1
Bódi, I; Rabloczky, G; Varró, A1
Hutchings, A; Morris, JM; Routledge, PA; Ward, MJ1
Connolly, SJ; Gupta, RN; Hoffert, D; Roberts, RS1
DiMarco, JP; Greenberg, ML; Kaiser, DL; Lerman, BB; Shipe, JR1
Falik, R; Flores, BT; Gibson, GA; Josephson, ME; Marchlinski, FE; Shaw, L1
Batsford, WP; Bookbinder, MJ; Kennedy, EE; McPherson, CA; Perlmutter, RA; Rosenfeld, LF1
Barbieri, E; Conti, F; d'Aranno, V; Latini, R; Trevi, GP; Zampieri, P; Zardini, P1
Bucknall, CA; Curry, PV; Holt, DW; Keeton, BR; Sutherland, GR; Tynan, MJ1
McManus, K; Simon, VA; Somani, P1
Coumel, P; Escoubet, B; Jaillon, P; Leclercq, JF; Maison-Blanche, P; Poirier, JM; Slama, R1
Adams, PC; Callaghan, J; Campbell, RW; Holt, DW; Morley, AR; Storey, GC1
Berger, Y; Commin, P; Echter, E; Escoubet, B; Jaillon, P; Menasché, P; Piwnica, A1
Annesley, T; Baerman, JM; Crevey, BJ; DiCarlo, LA; Foley, MK; Morady, F; Nicklas, JM1
Cheymol, G; Coumel, P; Escoubet, B; Jaillon, P; Lagier, G; Leclercq, JF; Maison-Blanche, P; Menasche, P; Piwnica, A; Poirier, JM1
Holt, DW; Jeeva Raj, MV; Robson, DJ; Storey, GC1
Balmer, P; Bircher, J; Kohler, B; Schmid, B; Stäubli, M; Studer, H; Troendle, A1

Trials

5 trial(s) available for desethylamiodarone and Arrhythmias, Cardiac

ArticleYear
Effect of amiodarone on the serum concentration/dose ratio of metoprolol in patients with cardiac arrhythmia.
    Drug metabolism and pharmacokinetics, 2006, Volume: 21, Issue:6

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Metoprolol; Middle Aged

2006
Multicenter controlled observation of a low-dose regimen of amiodarone for treatment of severe ventricular arrhythmias. Collaborative Group for Amiodarone Evaluation.
    The American journal of cardiology, 1984, Jun-01, Volume: 53, Issue:11

    Topics: Adolescent; Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Child; Clinical Trials as Topic; Electrocardiography; Female; Heart Ventricles; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Prospective Studies; Systole

1984
Clinical electrophysiologic effects of a single high oral dose of amiodarone.
    Fundamental & clinical pharmacology, 1997, Volume: 11, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrioventricular Node; Bundle of His; Electrocardiography; Electrophysiology; Female; Heart Atria; Humans; Male; Middle Aged; Purkinje Fibers; Sinoatrial Node; Ventricular Function, Right

1997
Relationship between preoperative amiodarone treatment and complications observed during anaesthesia for valvular cardiac surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:2

    Topics: Adult; Aged; Amiodarone; Anesthesia, General; Aortic Valve; Arrhythmias, Cardiac; Depression, Chemical; Female; Heart Valve Prosthesis; Hemodynamics; Humans; Male; Middle Aged; Mitral Valve; Myocardial Contraction; Random Allocation

1990
Amiodarone and N-desethylamiodarone concentrations in plasma, red blood cells, and myocardium after a single oral dose: relation to hemodynamic effects in surgical patients.
    American heart journal, 1986, Volume: 111, Issue:2

    Topics: Administration, Oral; Adult; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Blood Pressure; Erythrocytes; Female; Heart Rate; Heart Valves; Hemodynamics; Humans; Male; Middle Aged; Myocardium; Postoperative Complications; Stroke Volume; Vascular Resistance

1986

Other Studies

34 other study(ies) available for desethylamiodarone and Arrhythmias, Cardiac

ArticleYear
Trace amine-associated receptor 1 (TAAR1) is activated by amiodarone metabolites.
    Bioorganic & medicinal chemistry letters, 2008, Nov-15, Volume: 18, Issue:22

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Combinatorial Chemistry Techniques; Humans; Mice; Molecular Structure; Rats; Receptors, G-Protein-Coupled

2008
Long-term pretreatment with desethylamiodarone (DEA) or amiodarone (AMIO) protects against coronary artery occlusion induced ventricular arrhythmias in conscious rats.
    Canadian journal of physiology and pharmacology, 2015, Volume: 93, Issue:9

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiotonic Agents; Consciousness; Coronary Occlusion; Male; Myocardium; Rats

2015
[Control of anti-arrhythmia therapy with amiodarone. Value of the determination of blood levels].
    Deutsche medizinische Wochenschrift (1946), 1984, Mar-30, Volume: 109, Issue:13

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Erythrocytes; Humans; Long-Term Care; Middle Aged; Pulmonary Fibrosis

1984
Steady-state serum amiodarone concentrations: relationships with antiarrhythmic efficacy and toxicity.
    Annals of internal medicine, 1984, Volume: 101, Issue:4

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Middle Aged; Recurrence; Tachycardia; Ventricular Fibrillation

1984
[Pharmacological and clinical research on the interaction of digitalis and amiodarone in heart disease patients with varying degrees of cardiac insufficiency].
    Giornale italiano di cardiologia, 1984, Volume: 14, Issue:12

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Digitalis Glycosides; Digoxin; Drug Interactions; Female; Heart Diseases; Humans; Male; Medigoxin; Middle Aged

1984
Renal elimination of amiodarone and its desethyl metabolite.
    Postgraduate medical journal, 1983, Volume: 59, Issue:693

    Topics: Amiodarone; Arrhythmias, Cardiac; Benzofurans; Female; Humans; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis; Renal Dialysis

1983
Measurement of tissue-bound amiodarone and its metabolites by computed tomography.
    Clinical radiology, 1994, Volume: 49, Issue:1

    Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Female; Humans; Iodine; Liver; Male; Middle Aged; Models, Structural; Tomography, X-Ray Computed

1994
Measurement of serum amiodarone and desethylamiodarone by HPLC: its usefulness in the follow-up of arrhythmic patients treated with amiodarone.
    International journal of clinical pharmacology research, 1995, Volume: 15, Issue:2

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chromatography, High Pressure Liquid; Female; Follow-Up Studies; Humans; Male; Middle Aged

1995
Amiodarone-Induced thyroid dysfunction and ventricular tachyarrhythmias during long-term therapy in Japan.
    Japanese circulation journal, 2001, Volume: 65, Issue:11

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Drug Evaluation; Female; Follow-Up Studies; Humans; Hyperthyroidism; Hypothyroidism; Japan; Male; Middle Aged; Recurrence; Tachycardia, Ventricular; Thyroid Diseases; Ventricular Premature Complexes

2001
Use of amiodarone during pregnancy.
    European journal of obstetrics, gynecology, and reproductive biology, 1992, Feb-28, Volume: 43, Issue:3

    Topics: Amiodarone; Arrhythmias, Cardiac; Female; Fetal Blood; Humans; Hypothyroidism; Infant, Newborn; Lactation; Male; Maternal-Fetal Exchange; Milk, Human; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Thyroid Hormones

1992
Antiarrhythmic effect of chronic oral amiodarone treatment in dogs with myocardial infarction and reproducibly inducible sustained ventricular arrhythmias.
    Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:5

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Electric Stimulation; Electrocardiography; Male; Myocardial Infarction; Refractory Period, Electrophysiological

1990
Relationship between myocardial amiodarone concentration and antiarrhythmic effect in dogs with myocardial infarction and electrically induced ventricular arrhythmias.
    Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:6

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Electric Stimulation; Heart Ventricles; Myocardial Infarction; Myocardium; Ventricular Fibrillation

1991
Influence of amiodarone on genetically determined drug metabolism in humans.
    Clinical pharmacology and therapeutics, 1991, Volume: 50, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Arrhythmias, Cardiac; Arylamine N-Acetyltransferase; Cytochrome P-450 Enzyme System; Dextromethorphan; Female; Humans; Isoniazid; Liver; Male; Mephenytoin; Middle Aged; Phenotype

1991
Amiodarone- and desethylamiodarone-induced myelinoid inclusion bodies and toxicity in cultured rat hepatocytes.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:1

    Topics: Amiodarone; Animals; Arrhythmias, Cardiac; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Inclusion Bodies; L-Lactate Dehydrogenase; Lethal Dose 50; Liver; Male; Microscopy, Electron; Rats; Rats, Inbred Strains

1990
Rapid control of refractory atrial tachyarrhythmias with high-dose oral amiodarone.
    American heart journal, 1990, Volume: 120, Issue:6 Pt 1

    Topics: Administration, Oral; Amiodarone; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Drug Evaluation; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Heart Atria; Humans; Male; Tablets; Tachycardia; Time Factors

1990
The antiarrhythmic efficacy of amiodarone and desethylamiodarone, alone and in combination, in dogs with acute myocardial infarction.
    Circulation, 1988, Volume: 77, Issue:1

    Topics: Amiodarone; Animals; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Dogs; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Male; Myocardial Infarction; Tachycardia; Time Factors

1988
Antiarrhythmic effects of desethylamiodarone in dogs with subacute myocardial infarction and inducible ventricular arrhythmias.
    Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:1

    Topics: Amiodarone; Animals; Arrhythmias, Cardiac; Dogs; Electric Stimulation; Infusions, Intravenous; Male; Myocardial Infarction; Refractory Period, Electrophysiological

1989
Anti-arrhythmic effects of amiodarone and desethylamiodarone on malignant ventricular arrhythmias arising as a consequence of ischaemia and reperfusion in the anaesthetised rat.
    Cardiovascular research, 1989, Volume: 23, Issue:4

    Topics: Amiodarone; Anesthesia, Intravenous; Animals; Arrhythmias, Cardiac; Coronary Disease; Heart Ventricles; Hemodynamics; Male; Myocardial Reperfusion Injury; Rats; Rats, Inbred Strains

1989
Antiarrhythmic effect of desethylamiodarone in conscious rats.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:6

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Injections, Intraperitoneal; Male; Myocardium; Rats

1987
Association of seminal desethylamiodarone concentration and epididymitis with amiodarone treatment.
    British medical journal (Clinical research ed.), 1988, Jan-02, Volume: 296, Issue:6614

    Topics: Adult; Amiodarone; Arrhythmias, Cardiac; Epididymitis; Humans; Male; Semen

1988
Concentration response relationships of amiodarone and desethylamiodarone.
    American heart journal, 1988, Volume: 115, Issue:6

    Topics: Amiodarone; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Electrocardiography; Humans; Time Factors

1988
Relation between amiodarone and desethylamiodarone plasma concentrations and electrophysiologic effects, efficacy and toxicity.
    Journal of the American College of Cardiology, 1987, Volume: 9, Issue:5

    Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Coronary Disease; Dose-Response Relationship, Drug; Electrocardiography; Electrophoresis; Female; Humans; Male; Middle Aged; Osmolar Concentration; Recurrence

1987
Relationship of steady-state serum concentrations of amiodarone and desethylamiodarone to therapeutic efficacy and adverse effects.
    The American journal of medicine, 1987, Volume: 82, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Arrhythmias, Cardiac; Female; Humans; Male; Middle Aged; Risk; Time Factors

1987
Dissociation of electrophysiologic and pharmacologic stability during an abbreviated oral loading regimen of amiodarone.
    American heart journal, 1987, Volume: 114, Issue:6

    Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Evaluation; Electrophysiology; Female; Heart Ventricles; Humans; Male; Middle Aged; Ventricular Fibrillation

1987
Rapid suppression of complex ventricular arrhythmias with high-dose oral amiodarone.
    Circulation, 1986, Volume: 73, Issue:6

    Topics: Administration, Oral; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Drug Administration Schedule; Electrocardiography; Follow-Up Studies; Heart Rate; Heart Ventricles; Hemodynamics; Humans; Kinetics

1986
Amiodarone and desethylamiodarone distribution in the atrium and adipose tissue of patients undergoing short- and long-term treatment with amiodarone.
    Journal of the American College of Cardiology, 1986, Volume: 8, Issue:1

    Topics: Adipose Tissue; Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Cardiac Surgical Procedures; Heart Atria; Humans; Kinetics; Middle Aged; Myocardium; Time Factors

1986
Intravenous and oral amiodarone for arrhythmias in children.
    British heart journal, 1986, Volume: 56, Issue:3

    Topics: Administration, Oral; Adolescent; Amiodarone; Arrhythmias, Cardiac; Atrial Flutter; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Injections, Intravenous; Male; Tachycardia

1986
Pharmacokinetics, antiarrhythmic effects, and tissue concentrations of amiodarone and desethylamiodarone in dogs with acute coronary artery occlusion.
    The Canadian journal of cardiology, 1985, Volume: 1, Issue:1

    Topics: Amiodarone; Animals; Arrhythmias, Cardiac; Benzofurans; Biotransformation; Chromatography, High Pressure Liquid; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Conduction System; Hemodynamics; Male; Myocardial Infarction; Myocardium

1985
[Anti-arrhythmic effect of amiodarone in the 24 hours following a single oral loading dose. Clinical and pharmacological study].
    Archives des maladies du coeur et des vaisseaux, 1985, Volume: 78, Issue:7

    Topics: Administration, Oral; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Male

1985
Amiodarone and its desethyl metabolite: tissue distribution and morphologic changes during long-term therapy.
    Circulation, 1985, Volume: 72, Issue:5

    Topics: Adolescent; Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Coronary Disease; Female; Humans; Liver; Long-Term Care; Lung; Male; Middle Aged; Skin

1985
Interrelationships between serum levels of amiodarone, desethylamiodarone, reverse T3 and the QT interval during long-term amiodarone treatment.
    American heart journal, 1986, Volume: 111, Issue:4

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Time Factors; Triiodothyronine, Reverse

1986
Suppression of arrhythmias within hours after a single oral dose of amiodarone and relation to plasma and myocardial concentrations.
    The American journal of cardiology, 1985, Mar-01, Volume: 55, Issue:6

    Topics: Administration, Oral; Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Atrial Fibrillation; Atrioventricular Node; Benzofurans; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Atria; Humans; Male; Middle Aged; Myocardium; Tachycardia; Time Factors

1985
Use of amiodarone during pregnancy.
    Postgraduate medical journal, 1985, Volume: 61, Issue:711

    Topics: Adult; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Female; Humans; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications, Cardiovascular

1985
Pharmacokinetics of amiodarone, desethylamiodarone and other iodine-containing amiodarone metabolites.
    European journal of clinical pharmacology, 1985, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Aged; Amiodarone; Angina Pectoris; Arrhythmias, Cardiac; Benzofurans; Female; Half-Life; Humans; Iodides; Iodine; Kinetics; Male; Middle Aged; Time Factors

1985