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desethylamiodarone and Arrhythmia

desethylamiodarone has been researched along with Arrhythmia in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199025 (64.10)18.7374
1990's10 (25.64)18.2507
2000's3 (7.69)29.6817
2010's1 (2.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miyakawa, M; Scanlan, TS; Snead, AN; Tan, ES1
Baczkó, I; Falkay, G; Leprán, I; Morvay, N; Papp, JG; Sztojkov-Ivanov, A; Varró, A1
Fukumoto, K; Kamakura, S; Kato, R; Kitakaze, M; Kobayashi, T; Komamura, K; Tachibana, K; Tanaka, K; Ueno, K1
Lüderitz, B; Nitsch, J1
Belhassen, B; Greenspan, AM; Greenspon, AJ; Horowitz, LN; Rotmensch, HH; Shoshani, D; Spielman, SR; Swanson, BN; Vlasses, PH1
Aquili, C; Ferrari, M; Fornaro, G; Fortina, A; Padrini, R; Piovan, D; Rossi, P; Tomassini, G1
Harris, L; Hind, CR; Holt, DW; Krikler, SJ; McKenna, WJ; Savage, C; Storey, GC1
Caplin, JL; Nicholson, AA; Steventon, DM1
Berti, S; Biagini, A; Cazzuola, F; Clerico, A; Iervasi, G; Manfredi, C; Sabatino, L; Turchi, S1
Bory, M; Deharo, JC; Djiane, P; Durand, A; Le Tallec, L; Macaluso, G; Malaterre, H; Panagides, D1
Hagiwara, N; Kasanuki, H; Matsuda, N; Sato, K; Shiga, T; Shoda, M; Wakaumi, M1
de Vijlder, JJ; Plomp, TA; Vulsma, T1
Abdollah, H; Brennan, FJ; Brien, JF2
Abdollah, H; Brennan, FJ; Brien, JF; Jimmo, S1
Funck-Brentano, C; Jacqz-Aigrain, E; Jaillon, P; Leenhardt, A; Poirier, JM; Roux, A1
Bastien, O; Chassard, D; Estanove, S; George, M; Guiraud, M; Hercule, C; Lehot, JJ; Villard, J1
Bandyopadhyay, S; Gross, SA; Klaunig, JE; Somani, P1
Mostow, ND; Noon, D; Rakita, L; Vrobel, TR2
Davies, M; Nattel, S; Quantz, M1
Hearse, DJ; Riva, E1
Bódi, I; Rabloczky, G; Varró, A1
Hutchings, A; Morris, JM; Routledge, PA; Ward, MJ1
Connolly, SJ; Gupta, RN; Hoffert, D; Roberts, RS1
DiMarco, JP; Greenberg, ML; Kaiser, DL; Lerman, BB; Shipe, JR1
Falik, R; Flores, BT; Gibson, GA; Josephson, ME; Marchlinski, FE; Shaw, L1
Batsford, WP; Bookbinder, MJ; Kennedy, EE; McPherson, CA; Perlmutter, RA; Rosenfeld, LF1
Barbieri, E; Conti, F; d'Aranno, V; Latini, R; Trevi, GP; Zampieri, P; Zardini, P1
Bucknall, CA; Curry, PV; Holt, DW; Keeton, BR; Sutherland, GR; Tynan, MJ1
McManus, K; Simon, VA; Somani, P1
Coumel, P; Escoubet, B; Jaillon, P; Leclercq, JF; Maison-Blanche, P; Poirier, JM; Slama, R1
Adams, PC; Callaghan, J; Campbell, RW; Holt, DW; Morley, AR; Storey, GC1
Berger, Y; Commin, P; Echter, E; Escoubet, B; Jaillon, P; Menasché, P; Piwnica, A1
Annesley, T; Baerman, JM; Crevey, BJ; DiCarlo, LA; Foley, MK; Morady, F; Nicklas, JM1
Cheymol, G; Coumel, P; Escoubet, B; Jaillon, P; Lagier, G; Leclercq, JF; Maison-Blanche, P; Menasche, P; Piwnica, A; Poirier, JM1
Holt, DW; Jeeva Raj, MV; Robson, DJ; Storey, GC1
Balmer, P; Bircher, J; Kohler, B; Schmid, B; Stäubli, M; Studer, H; Troendle, A1

Trials

5 trial(s) available for desethylamiodarone and Arrhythmia

ArticleYear
Effect of amiodarone on the serum concentration/dose ratio of metoprolol in patients with cardiac arrhythmia.
    Drug metabolism and pharmacokinetics, 2006, Volume: 21, Issue:6

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Metoprolol; Middle Aged

2006
Multicenter controlled observation of a low-dose regimen of amiodarone for treatment of severe ventricular arrhythmias. Collaborative Group for Amiodarone Evaluation.
    The American journal of cardiology, 1984, Jun-01, Volume: 53, Issue:11

    Topics: Adolescent; Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Child; Clinical Trials as Topic; Electrocardiography; Female; Heart Ventricles; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Prospective Studies; Systole

1984
Clinical electrophysiologic effects of a single high oral dose of amiodarone.
    Fundamental & clinical pharmacology, 1997, Volume: 11, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrioventricular Node; Bundle of His; Electrocardiography; Electrophysiology; Female; Heart Atria; Humans; Male; Middle Aged; Purkinje Fibers; Sinoatrial Node; Ventricular Function, Right

1997
Relationship between preoperative amiodarone treatment and complications observed during anaesthesia for valvular cardiac surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:2

    Topics: Adult; Aged; Amiodarone; Anesthesia, General; Aortic Valve; Arrhythmias, Cardiac; Depression, Chemical; Female; Heart Valve Prosthesis; Hemodynamics; Humans; Male; Middle Aged; Mitral Valve; Myocardial Contraction; Random Allocation

1990
Amiodarone and N-desethylamiodarone concentrations in plasma, red blood cells, and myocardium after a single oral dose: relation to hemodynamic effects in surgical patients.
    American heart journal, 1986, Volume: 111, Issue:2

    Topics: Administration, Oral; Adult; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Blood Pressure; Erythrocytes; Female; Heart Rate; Heart Valves; Hemodynamics; Humans; Male; Middle Aged; Myocardium; Postoperative Complications; Stroke Volume; Vascular Resistance

1986

Other Studies

34 other study(ies) available for desethylamiodarone and Arrhythmia

ArticleYear
Trace amine-associated receptor 1 (TAAR1) is activated by amiodarone metabolites.
    Bioorganic & medicinal chemistry letters, 2008, Nov-15, Volume: 18, Issue:22

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Combinatorial Chemistry Techniques; Humans; Mice; Molecular Structure; Rats; Receptors, G-Protein-Coupled

2008
Long-term pretreatment with desethylamiodarone (DEA) or amiodarone (AMIO) protects against coronary artery occlusion induced ventricular arrhythmias in conscious rats.
    Canadian journal of physiology and pharmacology, 2015, Volume: 93, Issue:9

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiotonic Agents; Consciousness; Coronary Occlusion; Male; Myocardium; Rats

2015
[Control of anti-arrhythmia therapy with amiodarone. Value of the determination of blood levels].
    Deutsche medizinische Wochenschrift (1946), 1984, Mar-30, Volume: 109, Issue:13

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Erythrocytes; Humans; Long-Term Care; Middle Aged; Pulmonary Fibrosis

1984
Steady-state serum amiodarone concentrations: relationships with antiarrhythmic efficacy and toxicity.
    Annals of internal medicine, 1984, Volume: 101, Issue:4

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Middle Aged; Recurrence; Tachycardia; Ventricular Fibrillation

1984
[Pharmacological and clinical research on the interaction of digitalis and amiodarone in heart disease patients with varying degrees of cardiac insufficiency].
    Giornale italiano di cardiologia, 1984, Volume: 14, Issue:12

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Digitalis Glycosides; Digoxin; Drug Interactions; Female; Heart Diseases; Humans; Male; Medigoxin; Middle Aged

1984
Renal elimination of amiodarone and its desethyl metabolite.
    Postgraduate medical journal, 1983, Volume: 59, Issue:693

    Topics: Amiodarone; Arrhythmias, Cardiac; Benzofurans; Female; Humans; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis; Renal Dialysis

1983
Measurement of tissue-bound amiodarone and its metabolites by computed tomography.
    Clinical radiology, 1994, Volume: 49, Issue:1

    Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Female; Humans; Iodine; Liver; Male; Middle Aged; Models, Structural; Tomography, X-Ray Computed

1994
Measurement of serum amiodarone and desethylamiodarone by HPLC: its usefulness in the follow-up of arrhythmic patients treated with amiodarone.
    International journal of clinical pharmacology research, 1995, Volume: 15, Issue:2

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chromatography, High Pressure Liquid; Female; Follow-Up Studies; Humans; Male; Middle Aged

1995
Amiodarone-Induced thyroid dysfunction and ventricular tachyarrhythmias during long-term therapy in Japan.
    Japanese circulation journal, 2001, Volume: 65, Issue:11

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Drug Evaluation; Female; Follow-Up Studies; Humans; Hyperthyroidism; Hypothyroidism; Japan; Male; Middle Aged; Recurrence; Tachycardia, Ventricular; Thyroid Diseases; Ventricular Premature Complexes

2001
Use of amiodarone during pregnancy.
    European journal of obstetrics, gynecology, and reproductive biology, 1992, Feb-28, Volume: 43, Issue:3

    Topics: Amiodarone; Arrhythmias, Cardiac; Female; Fetal Blood; Humans; Hypothyroidism; Infant, Newborn; Lactation; Male; Maternal-Fetal Exchange; Milk, Human; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Thyroid Hormones

1992
Antiarrhythmic effect of chronic oral amiodarone treatment in dogs with myocardial infarction and reproducibly inducible sustained ventricular arrhythmias.
    Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:5

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Electric Stimulation; Electrocardiography; Male; Myocardial Infarction; Refractory Period, Electrophysiological

1990
Relationship between myocardial amiodarone concentration and antiarrhythmic effect in dogs with myocardial infarction and electrically induced ventricular arrhythmias.
    Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:6

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Electric Stimulation; Heart Ventricles; Myocardial Infarction; Myocardium; Ventricular Fibrillation

1991
Influence of amiodarone on genetically determined drug metabolism in humans.
    Clinical pharmacology and therapeutics, 1991, Volume: 50, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Arrhythmias, Cardiac; Arylamine N-Acetyltransferase; Cytochrome P-450 Enzyme System; Dextromethorphan; Female; Humans; Isoniazid; Liver; Male; Mephenytoin; Middle Aged; Phenotype

1991
Amiodarone- and desethylamiodarone-induced myelinoid inclusion bodies and toxicity in cultured rat hepatocytes.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:1

    Topics: Amiodarone; Animals; Arrhythmias, Cardiac; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Inclusion Bodies; L-Lactate Dehydrogenase; Lethal Dose 50; Liver; Male; Microscopy, Electron; Rats; Rats, Inbred Strains

1990
Rapid control of refractory atrial tachyarrhythmias with high-dose oral amiodarone.
    American heart journal, 1990, Volume: 120, Issue:6 Pt 1

    Topics: Administration, Oral; Amiodarone; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Drug Evaluation; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Heart Atria; Humans; Male; Tablets; Tachycardia; Time Factors

1990
The antiarrhythmic efficacy of amiodarone and desethylamiodarone, alone and in combination, in dogs with acute myocardial infarction.
    Circulation, 1988, Volume: 77, Issue:1

    Topics: Amiodarone; Animals; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Dogs; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Male; Myocardial Infarction; Tachycardia; Time Factors

1988
Antiarrhythmic effects of desethylamiodarone in dogs with subacute myocardial infarction and inducible ventricular arrhythmias.
    Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:1

    Topics: Amiodarone; Animals; Arrhythmias, Cardiac; Dogs; Electric Stimulation; Infusions, Intravenous; Male; Myocardial Infarction; Refractory Period, Electrophysiological

1989
Anti-arrhythmic effects of amiodarone and desethylamiodarone on malignant ventricular arrhythmias arising as a consequence of ischaemia and reperfusion in the anaesthetised rat.
    Cardiovascular research, 1989, Volume: 23, Issue:4

    Topics: Amiodarone; Anesthesia, Intravenous; Animals; Arrhythmias, Cardiac; Coronary Disease; Heart Ventricles; Hemodynamics; Male; Myocardial Reperfusion Injury; Rats; Rats, Inbred Strains

1989
Antiarrhythmic effect of desethylamiodarone in conscious rats.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:6

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Injections, Intraperitoneal; Male; Myocardium; Rats

1987
Association of seminal desethylamiodarone concentration and epididymitis with amiodarone treatment.
    British medical journal (Clinical research ed.), 1988, Jan-02, Volume: 296, Issue:6614

    Topics: Adult; Amiodarone; Arrhythmias, Cardiac; Epididymitis; Humans; Male; Semen

1988
Concentration response relationships of amiodarone and desethylamiodarone.
    American heart journal, 1988, Volume: 115, Issue:6

    Topics: Amiodarone; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Electrocardiography; Humans; Time Factors

1988
Relation between amiodarone and desethylamiodarone plasma concentrations and electrophysiologic effects, efficacy and toxicity.
    Journal of the American College of Cardiology, 1987, Volume: 9, Issue:5

    Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Coronary Disease; Dose-Response Relationship, Drug; Electrocardiography; Electrophoresis; Female; Humans; Male; Middle Aged; Osmolar Concentration; Recurrence

1987
Relationship of steady-state serum concentrations of amiodarone and desethylamiodarone to therapeutic efficacy and adverse effects.
    The American journal of medicine, 1987, Volume: 82, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Arrhythmias, Cardiac; Female; Humans; Male; Middle Aged; Risk; Time Factors

1987
Dissociation of electrophysiologic and pharmacologic stability during an abbreviated oral loading regimen of amiodarone.
    American heart journal, 1987, Volume: 114, Issue:6

    Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Evaluation; Electrophysiology; Female; Heart Ventricles; Humans; Male; Middle Aged; Ventricular Fibrillation

1987
Rapid suppression of complex ventricular arrhythmias with high-dose oral amiodarone.
    Circulation, 1986, Volume: 73, Issue:6

    Topics: Administration, Oral; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Drug Administration Schedule; Electrocardiography; Follow-Up Studies; Heart Rate; Heart Ventricles; Hemodynamics; Humans; Kinetics

1986
Amiodarone and desethylamiodarone distribution in the atrium and adipose tissue of patients undergoing short- and long-term treatment with amiodarone.
    Journal of the American College of Cardiology, 1986, Volume: 8, Issue:1

    Topics: Adipose Tissue; Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Cardiac Surgical Procedures; Heart Atria; Humans; Kinetics; Middle Aged; Myocardium; Time Factors

1986
Intravenous and oral amiodarone for arrhythmias in children.
    British heart journal, 1986, Volume: 56, Issue:3

    Topics: Administration, Oral; Adolescent; Amiodarone; Arrhythmias, Cardiac; Atrial Flutter; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Injections, Intravenous; Male; Tachycardia

1986
Pharmacokinetics, antiarrhythmic effects, and tissue concentrations of amiodarone and desethylamiodarone in dogs with acute coronary artery occlusion.
    The Canadian journal of cardiology, 1985, Volume: 1, Issue:1

    Topics: Amiodarone; Animals; Arrhythmias, Cardiac; Benzofurans; Biotransformation; Chromatography, High Pressure Liquid; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Conduction System; Hemodynamics; Male; Myocardial Infarction; Myocardium

1985
[Anti-arrhythmic effect of amiodarone in the 24 hours following a single oral loading dose. Clinical and pharmacological study].
    Archives des maladies du coeur et des vaisseaux, 1985, Volume: 78, Issue:7

    Topics: Administration, Oral; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Male

1985
Amiodarone and its desethyl metabolite: tissue distribution and morphologic changes during long-term therapy.
    Circulation, 1985, Volume: 72, Issue:5

    Topics: Adolescent; Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Coronary Disease; Female; Humans; Liver; Long-Term Care; Lung; Male; Middle Aged; Skin

1985
Interrelationships between serum levels of amiodarone, desethylamiodarone, reverse T3 and the QT interval during long-term amiodarone treatment.
    American heart journal, 1986, Volume: 111, Issue:4

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Time Factors; Triiodothyronine, Reverse

1986
Suppression of arrhythmias within hours after a single oral dose of amiodarone and relation to plasma and myocardial concentrations.
    The American journal of cardiology, 1985, Mar-01, Volume: 55, Issue:6

    Topics: Administration, Oral; Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Atrial Fibrillation; Atrioventricular Node; Benzofurans; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Atria; Humans; Male; Middle Aged; Myocardium; Tachycardia; Time Factors

1985
Use of amiodarone during pregnancy.
    Postgraduate medical journal, 1985, Volume: 61, Issue:711

    Topics: Adult; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Female; Humans; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications, Cardiovascular

1985
Pharmacokinetics of amiodarone, desethylamiodarone and other iodine-containing amiodarone metabolites.
    European journal of clinical pharmacology, 1985, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Aged; Amiodarone; Angina Pectoris; Arrhythmias, Cardiac; Benzofurans; Female; Half-Life; Humans; Iodides; Iodine; Kinetics; Male; Middle Aged; Time Factors

1985