Compounds > desethylamiodarone
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desethylamiodarone and Acute Liver Injury, Drug-Induced

desethylamiodarone has been researched along with Acute Liver Injury, Drug-Induced in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bryant, MS; Guo, L; Ning, B; Ren, Z; Wu, Q; Xuan, J1
Endo, S; Fukami, T; Nakajima, M; Toyoda, Y; Yokoi, T1
Agoston, M; Blázovics, A; Fehér, E; Fehér, J; Hagymási, K; Orosz, Z; Orsi, F; Vereckei, A1
Hanniman, EA; McCarthy, TC; Pollak, PT; Sinal, CJ1
Carruthers, SG; Pollak, PT; Sharma, AD1

Other Studies

5 other study(ies) available for desethylamiodarone and Acute Liver Injury, Drug-Induced

ArticleYear
The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity.
    Toxicology letters, 2016, Jun-24, Volume: 253

    Topics: Activation, Metabolic; Amiodarone; Anti-Arrhythmia Agents; Benzoflavones; Cell Survival; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Hep G2 Cells; Hepatocytes; Humans; Ketoconazole; Time Factors; Transfection

2016
Stimulation of human monocytic THP-1 cells by metabolic activation of hepatotoxic drugs.
    Drug metabolism and pharmacokinetics, 2012, Volume: 27, Issue:6

    Topics: Albendazole; Amiodarone; B7-2 Antigen; Biotransformation; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Humans; Intercellular Adhesion Molecule-1; Interleukin-8; Ketoconazole; Leukemia, Myeloid; Microsomes, Liver; Monocytes; RNA, Messenger; Tumor Necrosis Factor-alpha; Up-Regulation

2012
Silymarin and vitamin E reduce amiodarone-induced lysosomal phospholipidosis in rats.
    Toxicology, 2003, Aug-28, Volume: 190, Issue:3

    Topics: Amiodarone; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Hepatocytes; Liver Diseases; Lysosomes; Male; Microscopy, Electron; Phospholipids; Random Allocation; Rats; Rats, Inbred F344; Silymarin; Thiobarbituric Acid Reactive Substances; Vitamin E

2003
Disruption of hepatic lipid homeostasis in mice after amiodarone treatment is associated with peroxisome proliferator-activated receptor-alpha target gene activation.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:3

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Blood Glucose; Blotting, Northern; Body Weight; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, Reporter; Hepatocytes; Hepatomegaly; Homeostasis; Lipid Metabolism; Liver; Liver Neoplasms; Mice; Mice, Inbred C57BL; Mice, Knockout; PPAR alpha; Transcriptional Activation

2004
Relation of amiodarone hepatic and pulmonary toxicity to serum drug concentrations and superoxide dismutase activity.
    The American journal of cardiology, 1990, May-15, Volume: 65, Issue:18

    Topics: Alanine Transaminase; Amiodarone; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; Female; Humans; Liver Diseases; Lung Diseases; Male; Middle Aged; Pulmonary Diffusing Capacity; Superoxide Dismutase

1990