dequalinium has been researched along with Vaginosis, Bacterial in 9 studies
Dequalinium: A topical bacteriostat that is available as various salts. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration.
dequalinium : A quinolinium ion comprising decane in which one methyl hydrogen at each end of the molecule has been replaced by a 4-amino-2-methylquinolin-1-yl group.
Vaginosis, Bacterial: Polymicrobial, nonspecific vaginitis associated with positive cultures of Gardnerella vaginalis and other anaerobic organisms and a decrease in lactobacilli. It remains unclear whether the initial pathogenic event is caused by the growth of anaerobes or a primary decrease in lactobacilli.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Both treatments were well tolerated with no serious adverse events occurring." | 2.77 | A comparison of dequalinium chloride vaginal tablets (Fluomizin®) and clindamycin vaginal cream in the treatment of bacterial vaginosis: a single-blind, randomized clinical trial of efficacy and safety. ( Donders, G; Gerber, S; Halaška, M; Martinez de Tejada, B; Špaček, J; Unzeitig, V; Weissenbacher, ER, 2012) |
| "Those are bacterial vaginosis (BV), vulvovaginal candidosis (VVC), aerobic vaginitis (AV) associated with aerobic bacteria, and mixed infections." | 2.53 | Use of locally delivered dequalinium chloride in the treatment of vaginal infections: a review. ( Gerber, S; Grob, P; Mendling, W; Prasauskas, V; Weissenbacher, ER, 2016) |
| "When women with comorbid bacterial vaginosis visit periodontologist, it is essential to understand the presence of cross-infection processes between the oral cavity and vagina in this particular category of subjects." | 1.91 | COMPARISON OF THE IMPACT OF ANTISEPTIC AGENTS ON GARDNERELLA VAGINALIS AND ATOPOBIUM VAGINAE DETECTED IN THE ORAL CAVITY OF WOMEN WITH BACTERIAL VAGINOSIS. ( Boichenko, O; Ivanytskyi, I; Krutikova, A; Krutikova, E; Moshel, T; Petrushanko, T, 2023) |
| "Bacterial vaginosis is an infection characterised by overgrowth of anaerobic bacteria in the vagina with an accompanying loss of lactobacilli, and is thought to be the most common cause of abnormal vaginal discharge in women of child-bearing age." | 1.46 | Dequalinium for bacterial vaginosis. ( , 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Haydock, R | 1 |
| Hepburn, T | 1 |
| Ross, J | 1 |
| Daniels, J | 1 |
| Brittain, C | 1 |
| Jackson, L | 1 |
| Ozolins, M | 1 |
| Wilson, J | 1 |
| Krutikova, A | 1 |
| Krutikova, E | 1 |
| Petrushanko, T | 1 |
| Boichenko, O | 1 |
| Moshel, T | 1 |
| Ivanytskyi, I | 1 |
| Antoni Vives, J | 1 |
| Cancelo, MJ | 1 |
| Losada, MÁ | 1 |
| Doménech, A | 1 |
| Mendling, W | 1 |
| Weissenbacher, ER | 2 |
| Gerber, S | 2 |
| Prasauskas, V | 1 |
| Grob, P | 2 |
| Donders, G | 2 |
| Bellen, G | 1 |
| Donders, F | 1 |
| Pinget, J | 1 |
| Vandevelde, I | 1 |
| Michiels, T | 1 |
| Byamughisa, J | 1 |
| Unzeitig, V | 1 |
| Martinez de Tejada, B | 1 |
| Halaška, M | 1 |
| Špaček, J | 1 |
| Lopes dos Santos Santiago, G | 1 |
| Verstraelen, H | 1 |
| Waser, F | 1 |
| Vaneechoutte, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase III Comparative Study of Efficacy of 10 mg Dequalinium Chloride (Fluomizin) in the Local Treatment of Bacterial Vaginosis[NCT01125410] | Phase 3 | 321 participants (Actual) | Interventional | 2007-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for dequalinium and Vaginosis, Bacterial
| Article | Year |
|---|---|
Use of locally delivered dequalinium chloride in the treatment of vaginal infections: a review.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Antifungal Agents; Bacteria; Bacteria, Aerobic; | 2016 |
3 trials available for dequalinium and Vaginosis, Bacterial
| Article | Year |
|---|---|
The DEVA trial: protocol for a randomised controlled trial of dequalinium chloride versus usual care antibiotics for the treatment of bacterial vaginosis.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Dequalinium; Female; Humans; Metronidazole; Multicente | 2022 |
Improvement of abnormal vaginal flora in Ugandan women by self-testing and short use of intravaginal antimicrobials.
Topics: Adolescent; Adult; Anti-Infective Agents; Dequalinium; Diagnostic Tests, Routine; Double-Blind Metho | 2017 |
A comparison of dequalinium chloride vaginal tablets (Fluomizin®) and clindamycin vaginal cream in the treatment of bacterial vaginosis: a single-blind, randomized clinical trial of efficacy and safety.
Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Clindamycin; Dequalinium; Female; Follow-Up Studies; H | 2012 |
5 other studies available for dequalinium and Vaginosis, Bacterial
| Article | Year |
|---|---|
COMPARISON OF THE IMPACT OF ANTISEPTIC AGENTS ON GARDNERELLA VAGINALIS AND ATOPOBIUM VAGINAE DETECTED IN THE ORAL CAVITY OF WOMEN WITH BACTERIAL VAGINOSIS.
Topics: Anti-Infective Agents, Local; Dequalinium; Female; Gardnerella vaginalis; Humans; Mouth; Vagina; Vag | 2023 |
Dequalinium chloride use in adult Spanish women with bacterial vaginosis: an observational study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Dequalinium; Female; Human | 2022 |
Dequalinium for bacterial vaginosis.
Topics: Administration, Intravaginal; Anti-Bacterial Agents; Dequalinium; Female; Humans; Tablets; Vaginosis | 2017 |
[Statement of the Polish Gynecological Society expert panel concerning application of Fluomizin].
Topics: Anti-Infective Agents, Local; Dequalinium; Female; Gynecology; Humans; Inservice Training; National | 2013 |
Susceptibility testing of Atopobium vaginae for dequalinium chloride.
Topics: Actinobacteria; Anti-Bacterial Agents; Bacteroides fragilis; Clindamycin; Culture Media; Dequalinium | 2012 |