dequalinium has been researched along with Parkinson Disease in 1 studies
Dequalinium: A topical bacteriostat that is available as various salts. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration.
dequalinium : A quinolinium ion comprising decane in which one methyl hydrogen at each end of the molecule has been replaced by a 4-amino-2-methylquinolin-1-yl group.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "alpha-Synuclein is the major constituent of Lewy bodies, a pathological signature of Parkinson disease, found in the degenerating dopaminergic neurons of the substantia nigra pars compacta." | 3.73 | Dequalinium-induced protofibril formation of alpha-synuclein. ( Cho, HJ; Chung, KC; Jung, S; Kim, HJ; Kim, J; Lee, CH; Lee, JH; Paik, SR, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, CH | 1 |
| Kim, HJ | 1 |
| Lee, JH | 1 |
| Cho, HJ | 1 |
| Kim, J | 1 |
| Chung, KC | 1 |
| Jung, S | 1 |
| Paik, SR | 1 |
1 other study available for dequalinium and Parkinson Disease
| Article | Year |
|---|---|
Dequalinium-induced protofibril formation of alpha-synuclein.
Topics: alpha-Synuclein; Amyloid; Anti-Infective Agents, Local; Binding Sites; Cations; Cell Death; Cell Lin | 2006 |