Page last updated: 2024-10-25

dequalinium and Neoplasms

dequalinium has been researched along with Neoplasms in 5 studies

Dequalinium: A topical bacteriostat that is available as various salts. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration.
dequalinium : A quinolinium ion comprising decane in which one methyl hydrogen at each end of the molecule has been replaced by a 4-amino-2-methylquinolin-1-yl group.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Generally, cancer cells with mitochondrial genetic abnormalities (copy number change and mutations) have escalated ROS levels compared to normal cells."1.51ROS as a novel indicator to predict anticancer drug efficacy. ( An, Q; Ball, KE; Smith, JR; Zaidieh, T, 2019)
"We also found evidence of anticancer potential that mitochondrial-targeted DQA80s induced apoptosis by production of reactive oxygen species (ROS) via MAPK signaling pathways, loss of mitochondrial membrane potential, and the caspase-3 activation."1.48Dequalinium-based functional nanosomes show increased mitochondria targeting and anticancer effect. ( Bae, Y; Choi, JS; Green, ES; Han, J; Jung, MK; Ko, KS; Lee, S; Mun, JY; Song, SJ, 2018)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Zaidieh, T1
Smith, JR2
Ball, KE1
An, Q1
Bailly, C1
Bae, Y1
Jung, MK1
Lee, S1
Song, SJ1
Mun, JY1
Green, ES1
Han, J1
Ko, KS1
Choi, JS1
Theodoropoulos, D1
Rova, A1
Barbu, E1
Calabrese, G1
Vizirianakis, IS1
Tsibouklis, J1
Fatouros, DG1
Vaidya, B1
Vyas, SP1

Reviews

1 review available for dequalinium and Neoplasms

ArticleYear
Medicinal applications and molecular targets of dequalinium chloride.
    Biochemical pharmacology, 2021, Volume: 186

    Topics: Animals; Anti-Infective Agents, Local; Cell Cycle Proteins; Dequalinium; Drug Delivery Systems; Huma

2021

Other Studies

4 other studies available for dequalinium and Neoplasms

ArticleYear
ROS as a novel indicator to predict anticancer drug efficacy.
    BMC cancer, 2019, Dec-16, Volume: 19, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Cisplatin; Dequalin

2019
Dequalinium-based functional nanosomes show increased mitochondria targeting and anticancer effect.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2018, Volume: 124

    Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Dequalinium; Dose-Response Relationship, Dr

2018
Towards boron neutron capture therapy: the formulation and preliminary in vitro evaluation of liposomal vehicles for the therapeutic delivery of the dequalinium salt of bis-nido-carborane.
    Bioorganic & medicinal chemistry letters, 2013, Nov-15, Volume: 23, Issue:22

    Topics: Boron Neutron Capture Therapy; Dequalinium; Dimyristoylphosphatidylcholine; Humans; Liposomes; Neopl

2013
Transferrin coupled vesicular system for intracellular drug delivery for the treatment of cancer: development and characterization.
    Journal of drug targeting, 2012, Volume: 20, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Survival; Dequalinium; Drug Carriers; Dr

2012