dequalinium has been researched along with Neoplasms in 5 studies
Dequalinium: A topical bacteriostat that is available as various salts. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration.
dequalinium : A quinolinium ion comprising decane in which one methyl hydrogen at each end of the molecule has been replaced by a 4-amino-2-methylquinolin-1-yl group.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Generally, cancer cells with mitochondrial genetic abnormalities (copy number change and mutations) have escalated ROS levels compared to normal cells." | 1.51 | ROS as a novel indicator to predict anticancer drug efficacy. ( An, Q; Ball, KE; Smith, JR; Zaidieh, T, 2019) |
| "We also found evidence of anticancer potential that mitochondrial-targeted DQA80s induced apoptosis by production of reactive oxygen species (ROS) via MAPK signaling pathways, loss of mitochondrial membrane potential, and the caspase-3 activation." | 1.48 | Dequalinium-based functional nanosomes show increased mitochondria targeting and anticancer effect. ( Bae, Y; Choi, JS; Green, ES; Han, J; Jung, MK; Ko, KS; Lee, S; Mun, JY; Song, SJ, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zaidieh, T | 1 |
| Smith, JR | 2 |
| Ball, KE | 1 |
| An, Q | 1 |
| Bailly, C | 1 |
| Bae, Y | 1 |
| Jung, MK | 1 |
| Lee, S | 1 |
| Song, SJ | 1 |
| Mun, JY | 1 |
| Green, ES | 1 |
| Han, J | 1 |
| Ko, KS | 1 |
| Choi, JS | 1 |
| Theodoropoulos, D | 1 |
| Rova, A | 1 |
| Barbu, E | 1 |
| Calabrese, G | 1 |
| Vizirianakis, IS | 1 |
| Tsibouklis, J | 1 |
| Fatouros, DG | 1 |
| Vaidya, B | 1 |
| Vyas, SP | 1 |
1 review available for dequalinium and Neoplasms
| Article | Year |
|---|---|
Medicinal applications and molecular targets of dequalinium chloride.
Topics: Animals; Anti-Infective Agents, Local; Cell Cycle Proteins; Dequalinium; Drug Delivery Systems; Huma | 2021 |
4 other studies available for dequalinium and Neoplasms
| Article | Year |
|---|---|
ROS as a novel indicator to predict anticancer drug efficacy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Cisplatin; Dequalin | 2019 |
Dequalinium-based functional nanosomes show increased mitochondria targeting and anticancer effect.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Dequalinium; Dose-Response Relationship, Dr | 2018 |
Towards boron neutron capture therapy: the formulation and preliminary in vitro evaluation of liposomal vehicles for the therapeutic delivery of the dequalinium salt of bis-nido-carborane.
Topics: Boron Neutron Capture Therapy; Dequalinium; Dimyristoylphosphatidylcholine; Humans; Liposomes; Neopl | 2013 |
Transferrin coupled vesicular system for intracellular drug delivery for the treatment of cancer: development and characterization.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Survival; Dequalinium; Drug Carriers; Dr | 2012 |