dequalinium has been researched along with Necrosis in 4 studies
Dequalinium: A topical bacteriostat that is available as various salts. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration.
dequalinium : A quinolinium ion comprising decane in which one methyl hydrogen at each end of the molecule has been replaced by a 4-amino-2-methylquinolin-1-yl group.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dequalinium (DQA) is an antitumoral agent that selectively accumulates in the mitochondria and has been shown to display anticancer activity in cells from different malignancies." | 1.37 | Dequalinium induces apoptosis in peripheral blood mononuclear cells isolated from human chronic lymphocytic leukemia. ( Boyano-Adánez, Mdel C; Calviño, E; Diez, JC; Gil, J; Pajuelo, L; Sancho, P, 2011) |
| "Dequalinium (DQA) is a delocalized lipophylic cation that selectively targets the mitochondria of carcinoma cells." | 1.33 | Effects of the antitumoural dequalinium on NB4 and K562 human leukemia cell lines. Mitochondrial implication in cell death. ( Delgado, MD; Galeano, E; García-Pérez, AI; Nieto, E; Pinilla, M; Sancho, P, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pajuelo, L | 1 |
| Calviño, E | 1 |
| Diez, JC | 1 |
| Boyano-Adánez, Mdel C | 1 |
| Gil, J | 1 |
| Sancho, P | 2 |
| Gurovic, MS | 1 |
| Lanza, AM | 1 |
| Adánez, Mdel C | 1 |
| Omaña, MC | 1 |
| Gómez, IG | 1 |
| Murray, AP | 1 |
| López, PS | 1 |
| Galeano, E | 1 |
| Nieto, E | 1 |
| García-Pérez, AI | 1 |
| Delgado, MD | 1 |
| Pinilla, M | 1 |
| Chan, CF | 1 |
| Lin-Shiau, SY | 1 |
4 other studies available for dequalinium and Necrosis
| Article | Year |
|---|---|
Dequalinium induces apoptosis in peripheral blood mononuclear cells isolated from human chronic lymphocytic leukemia.
Topics: Antineoplastic Agents; Apoptosis; Cell Survival; Dequalinium; Humans; In Vitro Techniques; Leukemia, | 2011 |
Cytotoxic effects induced by combination of heliantriol B2 and dequalinium against human leukemic cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Dequalinium; Drug Therapy, Combinati | 2011 |
Effects of the antitumoural dequalinium on NB4 and K562 human leukemia cell lines. Mitochondrial implication in cell death.
Topics: Adenosine Triphosphate; Anti-Infective Agents, Local; Apoptosis; Cell Proliferation; Dequalinium; Hu | 2005 |
Site of action of suramin and reactive blue 2 in preventing neuronal death induced by dequalinium.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Cells, Cultured; C | 2000 |