Page last updated: 2024-10-25

dequalinium and Melanoma

dequalinium has been researched along with Melanoma in 1 studies

Dequalinium: A topical bacteriostat that is available as various salts. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration.
dequalinium : A quinolinium ion comprising decane in which one methyl hydrogen at each end of the molecule has been replaced by a 4-amino-2-methylquinolin-1-yl group.

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
" We have investigated whether the cationic lipophilic compound dequalinium affects not only proliferation but also motility and invasion of the highly metastatic and highly invasive melanoma cell line K1735-M2."7.68Effect of dequalinium on K1735-M2 melanoma cell growth, directional migration and invasion in vitro. ( Fink-Puches, R; Helige, C; Kerl, H; Smolle, J; Tritthart, HA; Zellnig, G, 1992)
" We have investigated whether the cationic lipophilic compound dequalinium affects not only proliferation but also motility and invasion of the highly metastatic and highly invasive melanoma cell line K1735-M2."3.68Effect of dequalinium on K1735-M2 melanoma cell growth, directional migration and invasion in vitro. ( Fink-Puches, R; Helige, C; Kerl, H; Smolle, J; Tritthart, HA; Zellnig, G, 1992)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Helige, C1
Smolle, J1
Zellnig, G1
Fink-Puches, R1
Kerl, H1
Tritthart, HA1

Other Studies

1 other study available for dequalinium and Melanoma

ArticleYear
Effect of dequalinium on K1735-M2 melanoma cell growth, directional migration and invasion in vitro.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 29A, Issue:1

    Topics: Animals; Dequalinium; Melanoma; Mice; Microscopy, Electron; Mitochondria; Mitosis; Neoplasm Invasive

1992