dequalinium has been researched along with Leukemia, Promyelocytic, Acute in 2 studies
Dequalinium: A topical bacteriostat that is available as various salts. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration.
dequalinium : A quinolinium ion comprising decane in which one methyl hydrogen at each end of the molecule has been replaced by a 4-amino-2-methylquinolin-1-yl group.
Leukemia, Promyelocytic, Acute: An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dequalinium (DQA) is a delocalized lipophylic cation that selectively targets the mitochondria of carcinoma cells." | 1.33 | Effects of the antitumoural dequalinium on NB4 and K562 human leukemia cell lines. Mitochondrial implication in cell death. ( Delgado, MD; Galeano, E; García-Pérez, AI; Nieto, E; Pinilla, M; Sancho, P, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gañán-Gómez, I | 1 |
| Estañ-Omaña, MC | 1 |
| Sancho, P | 2 |
| Aller, P | 1 |
| Boyano-Adánez, MC | 1 |
| Galeano, E | 1 |
| Nieto, E | 1 |
| García-Pérez, AI | 1 |
| Delgado, MD | 1 |
| Pinilla, M | 1 |
2 other studies available for dequalinium and Leukemia, Promyelocytic, Acute
| Article | Year |
|---|---|
Mechanisms of resistance to apoptosis in the human acute promyelocytic leukemia cell line NB4.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Nucl | 2015 |
Effects of the antitumoural dequalinium on NB4 and K562 human leukemia cell lines. Mitochondrial implication in cell death.
Topics: Adenosine Triphosphate; Anti-Infective Agents, Local; Apoptosis; Cell Proliferation; Dequalinium; Hu | 2005 |