dequalinium has been researched along with Leucocythaemia in 4 studies
Dequalinium: A topical bacteriostat that is available as various salts. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration.
dequalinium : A quinolinium ion comprising decane in which one methyl hydrogen at each end of the molecule has been replaced by a 4-amino-2-methylquinolin-1-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dequalinium (DQA) has been proposed as a selective antitumoral agent due to its preferential accumulation in mitochondria of cancer cells." | 5.34 | Dequalinium induces cell death in human leukemia cells by early mitochondrial alterations which enhance ROS production. ( Delgado, MD; Galeano, E; García-Pérez, AI; Nieto, E; Sancho, P, 2007) |
| "Dequalinium (DQA) has been proposed as a selective antitumoral agent due to its preferential accumulation in mitochondria of cancer cells." | 1.34 | Dequalinium induces cell death in human leukemia cells by early mitochondrial alterations which enhance ROS production. ( Delgado, MD; Galeano, E; García-Pérez, AI; Nieto, E; Sancho, P, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| García-Pérez, AI | 3 |
| Galeano, E | 3 |
| Nieto, E | 3 |
| Estañ, MC | 1 |
| Sancho, P | 3 |
| Gurovic, MS | 1 |
| Lanza, AM | 1 |
| Adánez, Mdel C | 1 |
| Omaña, MC | 1 |
| Gómez, IG | 1 |
| Murray, AP | 1 |
| López, PS | 1 |
| Delgado, MD | 1 |
4 other studies available for dequalinium and Leucocythaemia
| Article | Year |
|---|---|
Dequalinium induces cytotoxicity in human leukemia NB4 cells by downregulation of Raf/MEK/ERK and PI3K/Akt signaling pathways and potentiation of specific inhibitors of these pathways.
Topics: Apoptosis; Dequalinium; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Glutathione; Hu | 2014 |
Cytotoxic effects induced by combination of heliantriol B2 and dequalinium against human leukemic cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Dequalinium; Drug Therapy, Combinati | 2011 |
Dequalinium induces human leukemia cell death by affecting the redox balance.
Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Dequalinium; Drug Synergism; Glutathione; Humans; JN | 2011 |
Dequalinium induces cell death in human leukemia cells by early mitochondrial alterations which enhance ROS production.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 9; Cell Proliferation; | 2007 |