dequalinium has been researched along with Glioma in 4 studies
Dequalinium: A topical bacteriostat that is available as various salts. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration.
dequalinium : A quinolinium ion comprising decane in which one methyl hydrogen at each end of the molecule has been replaced by a 4-amino-2-methylquinolin-1-yl group.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our current understanding of the role of dequalinium chloride (DECA) in the progression of glioma remains very limited." | 7.96 | Dequalinium chloride inhibits the growth of human glioma cells in vitro and vivo: a study on molecular mechanism and potential targeted agents. ( Chen, F; Yang, B; Yu, J; Yu, Y; Zhao, G, 2020) |
| "Dequalinium chloride is an inhibitor of XIAP and can also act as a mitochondrial targeting agent, which gives it an interesting perspective regarding recent advances in the treatment of malignant glioma." | 6.72 | The potential value of dequalinium chloride in the treatment of cancer: Focus on malignant glioma. ( Chen, F; Pan, Y; Zhao, S, 2021) |
| "Invasive brain glioma is the most lethal type of cancer and is highly infiltrating." | 5.40 | Multifunctional liposomes loaded with paclitaxel and artemether for treatment of invasive brain glioma. ( Ju, RJ; Li, XT; Li, XY; Lou, JN; Lu, WL; Mu, LM; Shi, JF; Sun, MG; Zeng, F; Zhang, CX; Zhao, WY; Zhao, Y, 2014) |
| "Our current understanding of the role of dequalinium chloride (DECA) in the progression of glioma remains very limited." | 3.96 | Dequalinium chloride inhibits the growth of human glioma cells in vitro and vivo: a study on molecular mechanism and potential targeted agents. ( Chen, F; Yang, B; Yu, J; Yu, Y; Zhao, G, 2020) |
| "Dequalinium chloride is an inhibitor of XIAP and can also act as a mitochondrial targeting agent, which gives it an interesting perspective regarding recent advances in the treatment of malignant glioma." | 2.72 | The potential value of dequalinium chloride in the treatment of cancer: Focus on malignant glioma. ( Chen, F; Pan, Y; Zhao, S, 2021) |
| "Invasive brain glioma is the most lethal type of cancer and is highly infiltrating." | 1.40 | Multifunctional liposomes loaded with paclitaxel and artemether for treatment of invasive brain glioma. ( Ju, RJ; Li, XT; Li, XY; Lou, JN; Lu, WL; Mu, LM; Shi, JF; Sun, MG; Zeng, F; Zhang, CX; Zhao, WY; Zhao, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, Y | 1 |
| Yang, B | 1 |
| Yu, J | 1 |
| Zhao, G | 1 |
| Chen, F | 2 |
| Pan, Y | 1 |
| Zhao, S | 1 |
| Li, XY | 1 |
| Zhao, Y | 1 |
| Sun, MG | 1 |
| Shi, JF | 1 |
| Ju, RJ | 1 |
| Zhang, CX | 1 |
| Li, XT | 1 |
| Zhao, WY | 1 |
| Mu, LM | 1 |
| Zeng, F | 1 |
| Lou, JN | 1 |
| Lu, WL | 1 |
| Bodden, WL | 1 |
| Palayoor, ST | 1 |
| Hait, WN | 1 |
1 review available for dequalinium and Glioma
| Article | Year |
|---|---|
The potential value of dequalinium chloride in the treatment of cancer: Focus on malignant glioma.
Topics: Apoptosis; Dequalinium; Glioma; Humans; Mitochondria | 2021 |
3 other studies available for dequalinium and Glioma
| Article | Year |
|---|---|
Dequalinium chloride inhibits the growth of human glioma cells in vitro and vivo: a study on molecular mechanism and potential targeted agents.
Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dequalinium; Glioma; Humans | 2020 |
Multifunctional liposomes loaded with paclitaxel and artemether for treatment of invasive brain glioma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Artemether; Artemisinins; Blood-Brain Barrier; Brain; Bra | 2014 |
Selective antimitochondrial agents inhibit calmodulin.
Topics: Animals; Calmodulin; Cell Division; Cell Line; Dequalinium; Glioma; Kinetics; Mitochondria; Phosphor | 1986 |