Page last updated: 2024-10-25

dequalinium and Glioma

dequalinium has been researched along with Glioma in 4 studies

Dequalinium: A topical bacteriostat that is available as various salts. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration.
dequalinium : A quinolinium ion comprising decane in which one methyl hydrogen at each end of the molecule has been replaced by a 4-amino-2-methylquinolin-1-yl group.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"Our current understanding of the role of dequalinium chloride (DECA) in the progression of glioma remains very limited."7.96Dequalinium chloride inhibits the growth of human glioma cells in vitro and vivo: a study on molecular mechanism and potential targeted agents. ( Chen, F; Yang, B; Yu, J; Yu, Y; Zhao, G, 2020)
"Dequalinium chloride is an inhibitor of XIAP and can also act as a mitochondrial targeting agent, which gives it an interesting perspective regarding recent advances in the treatment of malignant glioma."6.72The potential value of dequalinium chloride in the treatment of cancer: Focus on malignant glioma. ( Chen, F; Pan, Y; Zhao, S, 2021)
"Invasive brain glioma is the most lethal type of cancer and is highly infiltrating."5.40Multifunctional liposomes loaded with paclitaxel and artemether for treatment of invasive brain glioma. ( Ju, RJ; Li, XT; Li, XY; Lou, JN; Lu, WL; Mu, LM; Shi, JF; Sun, MG; Zeng, F; Zhang, CX; Zhao, WY; Zhao, Y, 2014)
"Our current understanding of the role of dequalinium chloride (DECA) in the progression of glioma remains very limited."3.96Dequalinium chloride inhibits the growth of human glioma cells in vitro and vivo: a study on molecular mechanism and potential targeted agents. ( Chen, F; Yang, B; Yu, J; Yu, Y; Zhao, G, 2020)
"Dequalinium chloride is an inhibitor of XIAP and can also act as a mitochondrial targeting agent, which gives it an interesting perspective regarding recent advances in the treatment of malignant glioma."2.72The potential value of dequalinium chloride in the treatment of cancer: Focus on malignant glioma. ( Chen, F; Pan, Y; Zhao, S, 2021)
"Invasive brain glioma is the most lethal type of cancer and is highly infiltrating."1.40Multifunctional liposomes loaded with paclitaxel and artemether for treatment of invasive brain glioma. ( Ju, RJ; Li, XT; Li, XY; Lou, JN; Lu, WL; Mu, LM; Shi, JF; Sun, MG; Zeng, F; Zhang, CX; Zhao, WY; Zhao, Y, 2014)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Yu, Y1
Yang, B1
Yu, J1
Zhao, G1
Chen, F2
Pan, Y1
Zhao, S1
Li, XY1
Zhao, Y1
Sun, MG1
Shi, JF1
Ju, RJ1
Zhang, CX1
Li, XT1
Zhao, WY1
Mu, LM1
Zeng, F1
Lou, JN1
Lu, WL1
Bodden, WL1
Palayoor, ST1
Hait, WN1

Reviews

1 review available for dequalinium and Glioma

ArticleYear
The potential value of dequalinium chloride in the treatment of cancer: Focus on malignant glioma.
    Clinical and experimental pharmacology & physiology, 2021, Volume: 48, Issue:4

    Topics: Apoptosis; Dequalinium; Glioma; Humans; Mitochondria

2021

Other Studies

3 other studies available for dequalinium and Glioma

ArticleYear
Dequalinium chloride inhibits the growth of human glioma cells in vitro and vivo: a study on molecular mechanism and potential targeted agents.
    Acta neurochirurgica, 2020, Volume: 162, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dequalinium; Glioma; Humans

2020
Multifunctional liposomes loaded with paclitaxel and artemether for treatment of invasive brain glioma.
    Biomaterials, 2014, Volume: 35, Issue:21

    Topics: Animals; Antineoplastic Agents; Apoptosis; Artemether; Artemisinins; Blood-Brain Barrier; Brain; Bra

2014
Selective antimitochondrial agents inhibit calmodulin.
    Biochemical and biophysical research communications, 1986, Mar-13, Volume: 135, Issue:2

    Topics: Animals; Calmodulin; Cell Division; Cell Line; Dequalinium; Glioma; Kinetics; Mitochondria; Phosphor

1986