Page last updated: 2024-10-25

dequalinium and Candidiasis, Genital

dequalinium has been researched along with Candidiasis, Genital in 4 studies

Dequalinium: A topical bacteriostat that is available as various salts. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration.
dequalinium : A quinolinium ion comprising decane in which one methyl hydrogen at each end of the molecule has been replaced by a 4-amino-2-methylquinolin-1-yl group.

Research Excerpts

ExcerptRelevanceReference
" Both treatments were well tolerated with no serious adverse events occurring."2.77A comparison of dequalinium chloride vaginal tablets (Fluomizin®) and clindamycin vaginal cream in the treatment of bacterial vaginosis: a single-blind, randomized clinical trial of efficacy and safety. ( Donders, G; Gerber, S; Halaška, M; Martinez de Tejada, B; Špaček, J; Unzeitig, V; Weissenbacher, ER, 2012)
"Those are bacterial vaginosis (BV), vulvovaginal candidosis (VVC), aerobic vaginitis (AV) associated with aerobic bacteria, and mixed infections."2.53Use of locally delivered dequalinium chloride in the treatment of vaginal infections: a review. ( Gerber, S; Grob, P; Mendling, W; Prasauskas, V; Weissenbacher, ER, 2016)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Thamkhantho, M1
Chayachinda, C1
Mendling, W1
Weissenbacher, ER3
Gerber, S2
Prasauskas, V1
Grob, P1
Donders, G1
Unzeitig, V1
Martinez de Tejada, B1
Halaška, M1
Špaček, J1
Petersen, EE1
Hengst, P1
Spitzbart, H1
Weise, W1
Wolff, F1
Dreher, E1
Ernst, U1
Della Casa, V1
Pohlig, G1
Graf, F1
Kaiser, RR1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparative Study of the Efficacy of 10.0 mg Dequalinium Chloride (Fluomizin®) and 100 mg Clotrimazole (Canesten®) for the Treatment of Vulvovaginal Candidiasis[NCT02242695]Phase 4150 participants (Actual)Interventional2014-11-30Completed
Phase III Comparative Study of Efficacy of 10 mg Dequalinium Chloride (Fluomizin) in the Local Treatment of Bacterial Vaginosis[NCT01125410]Phase 3321 participants (Actual)Interventional2007-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for dequalinium and Candidiasis, Genital

ArticleYear
Use of locally delivered dequalinium chloride in the treatment of vaginal infections: a review.
    Archives of gynecology and obstetrics, 2016, Volume: 293, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Antifungal Agents; Bacteria; Bacteria, Aerobic;

2016

Trials

3 trials available for dequalinium and Candidiasis, Genital

ArticleYear
Vaginal tablets of dequalinium chloride 10 mg versus clotrimazole 100 mg for vaginal candidiasis: a double-blind, randomized study.
    Archives of gynecology and obstetrics, 2021, Volume: 303, Issue:1

    Topics: Adult; Anti-Infective Agents, Local; Antifungal Agents; Candidiasis, Vulvovaginal; Clotrimazole; Deq

2021
A comparison of dequalinium chloride vaginal tablets (Fluomizin®) and clindamycin vaginal cream in the treatment of bacterial vaginosis: a single-blind, randomized clinical trial of efficacy and safety.
    Gynecologic and obstetric investigation, 2012, Volume: 73, Issue:1

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Clindamycin; Dequalinium; Female; Follow-Up Studies; H

2012
Local treatment of vaginal infections of varying etiology with dequalinium chloride or povidone iodine. A randomised, double-blind, active-controlled, multicentric clinical study.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Candidiasis, Vulvovaginal;

2002