Page last updated: 2024-08-21

deoxyuridine and Lung Neoplasms

deoxyuridine has been researched along with Lung Neoplasms in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199012 (60.00)18.7374
1990's2 (10.00)18.2507
2000's2 (10.00)29.6817
2010's3 (15.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Knaus, EE; Mercer, JR; Wiebe, LI; Xu, LH1
Knaus, EE; Mercer, JR; Wiebe, LI1
Gong, Y; Sun, C; Zhang, Z; Zheng, Y1
Boellaard, R; Frings, V; Giovannetti, E; Herder, GJ; Hoekstra, OS; Honeywell, R; Peters, GJ; Smit, EF; Thunnissen, E; van der Veldt, AA1
Darzynkiewicz, Z; Dobrucki, JW; Kimmel, M; Li, B; Rybak, P; Zhao, H1
Dantzig, AH; Donoho, GP; Durland-Busbice, S; Perkins, EJ; Pratt, SE; Shepard, RL; Starling, JJ; Wickremsinhe, ER1
Clarke, SJ; Li, KM; Rivory, LP1
Chacón, RD; Filmus, J; Mordoh, J1
Ahmad, I; Allen, TM; Longenecker, M; Samuel, J1
Fukuoka, M; Kudoh, S; Masuda, N; Matsui, K; Myobudani, H; Nakagawa, K; Negoro, S; Nemoto, S; Nihira, S; Nogami, T; Ogawa, K; Okuda, T; Takeda, K; Takifuji, N; Yamada, M; Yamamoto, N1
Poirier, LA; Shimkin, MB; Stoner, GD1
Hägerström, T; Humla, S; Nordenskjöld, B; Skoog, L1
Jeney, A; Lapis, K; Major, J; Pogány, G; Timár, J1
Bungo, M; Fujita, J; Hashimoto, Y; Irino, S; Shiotani, T; Yamauchi, N1
Abrams, DN; Knaus, EE; Lee, YW; Mercer, JR; Wiebe, LI1
Cassidy, C; Chou, TC; Fanucchi, MP; Fleisher, M; Lokos, G; Niedzwiecki, D; Vidal, P; Walsh, TD; Williams, L; Young, CW1
Clarkson, BD; Duschinsky, R; Keller, O; Krakoff, IH; La Sala, E; Van Dyk, JJ1
Parks, RC1
Dedrick, RL; Drake, JC; Lutz, RJ; Peale, AL; Zaharko, DS1

Reviews

1 review(s) available for deoxyuridine and Lung Neoplasms

ArticleYear
Radiation sensitizers.
    Cancer, 1976, Volume: 37, Issue:4 Suppl

    Topics: Animals; Antineoplastic Agents; Bromodeoxycytidine; Bromodeoxyuridine; Carcinoma; Deoxyuridine; Dogs; Dose-Response Relationship, Radiation; Floxuridine; Humans; Hypoxia; Idoxuridine; Lung Neoplasms; Methotrexate; Metronidazole; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Research; Sarcoma, Experimental; Skin

1976

Trials

2 trial(s) available for deoxyuridine and Lung Neoplasms

ArticleYear
Pemetrexed pharmacokinetics and pharmacodynamics in a phase I/II study of doublet chemotherapy with vinorelbine: implications for further optimisation of pemetrexed schedules.
    British journal of cancer, 2007, Oct-22, Volume: 97, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carcinoma, Non-Small-Cell Lung; Deoxyuridine; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Glutamates; Guanine; Homocysteine; Humans; Lung Neoplasms; Male; Methylmalonic Acid; Middle Aged; Pemetrexed; Thymidine; Thymidylate Synthase; Vinblastine; Vinorelbine; Vitamin B 12

2007
Phase I trial of oral 2'-deoxy-2'-methylidenecytidine: on a daily x 14-day schedule.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:6

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Deoxycytidine; Deoxyuridine; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Time Factors

2000

Other Studies

17 other study(ies) available for deoxyuridine and Lung Neoplasms

ArticleYear
Synthesis and tumor uptake of 5-82Br- and 5-131I-labeled 5-halo-1-(2-fluoro-2-deoxy-beta-D-ribofuranosyl)uracils.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

    Topics: Animals; Biological Transport; Bromine Radioisotopes; Chemical Phenomena; Chemistry; DNA; Female; Floxuridine; Iodine Radioisotopes; Isotope Labeling; Lung Neoplasms; Mice; Molecular Structure; Structure-Activity Relationship; Tissue Distribution

1989
Synthesis and tumor uptake of 5-halo-1-(2'-fluoro-2'-deoxy-beta-D-ribofuranosyl)[2-14C]uracils.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Carcinoma; Carrier Proteins; Erythrocytes; Female; Floxuridine; Liver; Lung Neoplasms; Membrane Proteins; Metabolic Clearance Rate; Mice; Mice, Inbred Strains; Nucleoside Transport Proteins; Structure-Activity Relationship; Tissue Distribution

1987
circFCHO2 promotes gastric cancer progression by activating the JAK1/STAT3 pathway via sponging miR-194-5p.
    Cell cycle (Georgetown, Tex.), 2022, Volume: 21, Issue:20

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Deoxyuridine; Eosine Yellowish-(YS); Gene Expression Regulation, Neoplastic; Hematoxylin; Humans; In Situ Hybridization, Fluorescence; Janus Kinase 1; Lung Neoplasms; Membrane Proteins; Mice; Mice, Nude; MicroRNAs; RNA, Circular; STAT3 Transcription Factor; Stomach Neoplasms

2022
Pemetrexed induced thymidylate synthase inhibition in non-small cell lung cancer patients: a pilot study with 3'-deoxy-3'-[¹⁸F]fluorothymidine positron emission tomography.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Deoxyuridine; Dideoxynucleosides; Female; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Metastasis; Outcome Assessment, Health Care; Pemetrexed; Polymorphism, Genetic; Positron-Emission Tomography; Prognosis; Thymidylate Synthase; Time Factors; Tissue Distribution

2013
Different rates of DNA replication at early versus late S-phase sections: multiscale modeling of stochastic events related to DNA content/EdU (5-ethynyl-2'deoxyuridine) incorporation distributions.
    Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2014, Volume: 85, Issue:9

    Topics: Algorithms; Cell Division; Cell Line, Tumor; Computer Simulation; Deoxyuridine; DNA; DNA Replication; Flow Cytometry; G2 Phase; Humans; Laser Scanning Cytometry; Lung Neoplasms; Microscopy, Confocal; Models, Theoretical; S Phase

2014
Efficacy of low-dose oral metronomic dosing of the prodrug of gemcitabine, LY2334737, in human tumor xenografts.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:4

    Topics: Administration, Metronomic; Administration, Oral; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Deoxyuridine; Disease Models, Animal; Dose-Response Relationship, Drug; Gemcitabine; Gene Expression; HCT116 Cells; Humans; Lung Neoplasms; Mice; Prodrugs; Valproic Acid; Xenograft Model Antitumor Assays

2013
Isolation of tumor cells from patients with osteosarcoma and analysis of their sensitivity to methotrexate.
    Cancer research, 1981, Volume: 41, Issue:9 Pt 1

    Topics: Cell Separation; Cells, Cultured; Deoxyuridine; DNA; Drug Resistance; Humans; Hypoxanthines; Lung Neoplasms; Methotrexate; Osteosarcoma; Stimulation, Chemical; Thymidine

1981
Antibody-targeted delivery of doxorubicin entrapped in sterically stabilized liposomes can eradicate lung cancer in mice.
    Cancer research, 1993, Apr-01, Volume: 53, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Carcinoma, Squamous Cell; Deoxyuridine; Doxorubicin; Drug Carriers; Half-Life; Immunoglobulin G; Liposomes; Lung Neoplasms; Mice; Mice, Inbred DBA; Tumor Cells, Cultured

1993
Bioassay of alkyl halides and nucleotide base analogs by pulmonary tumor response in strain A mice.
    Cancer research, 1975, Volume: 35, Issue:6

    Topics: Adenoma; Alkanes; Animals; Biological Assay; Bromodeoxyuridine; Carcinogens; Deoxyuridine; Female; Floxuridine; Halogens; Idoxuridine; Lung Neoplasms; Male; Mice; Mice, Inbred A; Neoplasms, Experimental

1975
Effects of methotrexate on deoxyribonucleotide pools and nucleic acid synthesis in human osteosarcoma cells.
    European journal of cancer, 1976, Volume: 12, Issue:10

    Topics: Adolescent; Adult; Aged; Bone Marrow; Bone Marrow Cells; Breast Neoplasms; Cells, Cultured; Deoxyribonucleotides; Deoxyuridine; DNA; Female; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; RNA; Time Factors

1976
Modulation of glycoconjugate biosynthesis by 5-hexyl-2'-deoxyuridine in highly metastatic Lewis lung carcinoma cells.
    Neoplasma, 1990, Volume: 37, Issue:5

    Topics: Antimetabolites, Antineoplastic; Cell Line; Cell Nucleus; Chromatography, High Pressure Liquid; Cytoplasm; Deoxyuridine; Dose-Response Relationship, Drug; Glycoconjugates; Glycolipids; Glycoproteins; Glycosaminoglycans; Humans; In Vitro Techniques; Lung Neoplasms

1990
Improved assay method of dTMP synthase in rat liver and its application to human lung cancer cells.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Animals; Deoxyuridine; Humans; Kinetics; Liver; Liver Neoplasms, Experimental; Lung Neoplasms; Rats; Thymidylate Synthase; Tumor Cells, Cultured

1989
Tumour uptake of radiolabelled pyrimidine bases and pyrimidine nucleosides in animal models. IX. Radiolabelled 1-(2'-fluoro-2'-deoxy-beta-D-ribofuranosyl)uracil and 1-(2'-chloro-2'-deoxy-beta-D-ribofuranosyl)uracil.
    The British journal of radiology, 1986, Volume: 59, Issue:699

    Topics: Animals; Carbon Radioisotopes; Carcinoma 256, Walker; Chlorine; Deoxyuridine; Floxuridine; Lung Neoplasms; Mice; Radioisotopes; Rats; Rats, Inbred Strains; Tissue Distribution; Uracil; Uridine

1986
Phase I and clinical pharmacology study of trimetrexate administered weekly for three weeks.
    Cancer research, 1987, Jun-15, Volume: 47, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Bone Marrow; Chromatography, High Pressure Liquid; Deoxyuridine; Drug Evaluation; Female; Hematopoietic Stem Cells; Humans; Kinetics; Lung Neoplasms; Mathematics; Middle Aged; Quinazolines; Thrombocytopenia; Trimetrexate

1987
Clinical evaluation of 5-bromo-5-fluoro-6-methoxy-dihydro-2'-deoxyuridine.
    Cancer research, 1967, Volume: 27, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Animals; Bromodeoxyuridine; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Colonic Neoplasms; Deoxyuridine; Dogs; Female; Floxuridine; Gallbladder Neoplasms; Gastrointestinal Neoplasms; Humans; Ileocecal Valve; Intestinal Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Rectal Neoplasms; Sarcoma; Stomach Neoplasms

1967
Organ-specific metastasis of a transplantable reticulum cell sarcoma.
    Journal of the National Cancer Institute, 1974, Volume: 52, Issue:3

    Topics: Animals; Deoxyuridine; Female; Injections, Intravenous; Iodine Radioisotopes; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Lymphoma, Non-Hodgkin; Male; Mice; Mice, Inbred C3H; Neoplasm Metastasis; Sarcoma, Experimental; Splenic Neoplasms

1974
Relative toxicity of methotrexate in several tissues of mice bearing Lewis lung carcinoma.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:3

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Membrane; Cell Membrane Permeability; Deoxyuridine; DNA, Neoplasm; Femur; Intestine, Small; L-Lactate Dehydrogenase; Lung Neoplasms; Male; Methotrexate; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Tetrahydrofolate Dehydrogenase; Time Factors; Transplantation, Homologous; Tritium

1974