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deoxyuridine and Leukemia L 1210

deoxyuridine has been researched along with Leukemia L 1210 in 83 studies

Research

Studies (83)

Timeframe	Studies, this research(%)	All Research%
pre-1990	73 (87.95)	18.7374
1990's	10 (12.05)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Allen, TM; Knaus, EE; Kumar, R; Tovell, DR; Tyrrell, DL; Wiebe, LI; Xu, LH	1
Gao, YS; Lin, TS; Mancini, WR	1
Benz, C; Cadman, E; Heimer, R	1
Santi, DV; Washtien, WL	1
Cadman, E; Grant, S	1
Besserer, JA; Boritzki, TJ; Elslager, EF; Fry, DW; Jackson, RC; Leopold, WR; Sloan, BJ	1
Balzarini, J; Bigge, CF; Chang, CT; De Clercq, E; Descamps, J; Kalaritis, P; Mertes, MP	1
Balzarini, J; De Clercq, E; Duggan, MJ; Dyer, RL; Jones, AS; Rahim, SG; Walker, RT	1
Chou, TC; Talalay, P	1
Balzarini, J; Buchele, A; De Clercq, E; Keppeler, K; Kiefer, G	1
Calvert, AH; Harrap, KR; Jackman, AL; Taylor, GA	1
Block, JB; Chlebowski, RT; Dietrich, MF; Isacoff, WH	1
Beutler, E; Carson, DA; Wasson, DB	1
Perez, DJ; Tattersall, MH	1
Balzarini, J; De Clercq, E	1
Balzarini, J; De Clercq, E; Hunston, RN; Jones, AS; McGuigan, C; Walker, RT	1
Ayusawa, D; Balzarini, J; de Clercq, E; Seno, T	1
De Clercq, E	1
Cerna, I; Klubes, P	1
Cadman, E; Goldberg, D; Heimer, R	1
Momparler, LF; Momparler, RL; Rivard, GE	1
Browman, GP; Calvert, AH; Harrap, KR; Hart, LI; Taylor, GA	1
Balzarini, J; Barr, PJ; De Clercq, E; Jones, AS; Mertes, MP; Park, JS; Schmidt, CL; Shugar, D; Torrence, PF; Verhelst, G; Walker, RT	1
Katz, DJ; Townsend, LB; Wise, DS	1
Balzarini, J; De Clercq, E; Mertes, MP; Shugar, D; Torrence, PF	1
Balzarini, J; Barr, PJ; De Clercq, E; Jones, AS; Mertes, MP; Schmidt, CL; Shugar, D; Torrence, PF; Verhelst, G; Walker, RT	1
Higashigawa, M; Ido, M; Inagaki, S; Kagawa, Y; Kakito, H; Kojima, M; Ohkubo, T; Ooi, K; Sakurai, M	1
Allen, TM; Knaus, EE; Kumar, R; Wiebe, LF	1
Cory, AH; Cory, JG; Robins, MJ; Samano, V	1
Gowans, B; Hunting, DJ; Tremblay, S; Wagner, JR	1
Schreiber, C; Waxman, S	1
Bardos, TJ; Choi, S; Kalman, TI	1
Finch, LL; Johnson, JE; Moulton, GC	1
Fernandes, DJ; Klubes, P; Mandel, HG	1
Hart, LI; Jackson, RC; Niethammer, D	1
Cerna, I; Connelly, K; Klubes, P; Mandel, HG	1
Hofer, KG; Hofer, MG; Ieracitano, J; McLaughlin, WH	1
Hummel, H; Mattern, J; Volm, M	1
Horwitz, JP; Kessel, D; Maher, VM; McCormick, JJ; Otto, JR; Philips, KD; Zemlicka, J	1
Allen, TM; Knaus, EE; Kumar, R; Tempest, ML; Wiebe, LI	1
Goldman, ID; Rape, TJ; Seither, RL	2
Belt, JA; Cory, JG; Downes, DL; Ng, CY	1
Montgomery, JA; Riordan, JM; Secrist, JA; Tiwari, KN	1
Cory, JG; Halley, MC; Jeney, A; Lapis, K	1
Goldman, ID; Mikulecky, DC; Rape, TJ; Seither, RL; Trent, DF	1
Allen, TM; Fathi-Afshar, R; Hall, TW; Knaus, EE; Kumar, R; Tovell, DR; Tyrrell, DL; Wiebe, LI	1
Alison, DL; Calvert, AH; Harrap, KR; Jackman, AL	1
Brubaker, WF; Lin, TS; Park, S; Prusoff, WH; Wang, ZH	1
FitzGerald, GB; Ratliff, J; Wick, MM	1
Kalman, TI; Yalowich, JC	1
Karasawa, M; Maekawa, T; Omine, M; Yatabe, H	1
Brockman, RW; Elliott, RD; Montgomery, JA; Pruett, PS	1
Lin, TS; Prusoff, WH	1
Cory, JG; Ohmstede, CA	1
Balzarini, J	1
Hashimoto, K; Kinsky, SC; Knight, MS; Loader, JE	1
Miyake, H; Nakano, K; Okada, J	1
Jato, J; Windheuser, JJ	1
Durham, JP; Ives, DH	1
Bloch, A; McPartland, RP; Wang, MC; Weinfeld, H	1
Bhuyan, BK; Fraser, TJ; Li, LH; Olin, EJ	1
Kitz, R; Prensky, W; Schmidt, V; Wodinsky, I; Wonders, T; Zapol, W	1
Donsbach, RC; Sirotnak, FM	1
Chabner, BA; Young, RC	1
Bertino, JR; Cashmore, AR; Sawicki, WL; Skeel, RT	1
Hillcoat, BL; Kawai, M	1
Crawford, EJ; Friedkin, M; Livingston, D	1
Bertino, JR; Chabner, B; Levitt, M; McCullough, JL	1
Hartman, AC; Kensler, CJ; Okstein, C; Palm, PE; Rogers, WI	1
Hofer, KG	3
Mead, JA; Mishra, LC	1
Bertino, JR; Chabner, BA; Chello, PL	1
Bertino, JR; Capizzi, RL; Cashmore, AR; Johns, DG; Nahas, A	1
Bertino, JR; Hryniuk, WM	1
Abboud, G; Bertino, JR; Fölsch, E; Gralla, E	1
Himmelfarb, P; Roberts, D; Thayer, PS	1
Her, KG; Hughes, WL	1
Bertino, JR; Fölsch, E	1
Roberts, D; Wodinsky, I	1
Himmelfarb, P; Martin, HE; Thayer, PS	1

Reviews

2 review(s) available for deoxyuridine and Leukemia L 1210

Article	Year
Antiviral and antitumor activities of 5-substituted 2'-deoxyuridines. Methods and findings in experimental and clinical pharmacology, 1980, Volume: 2, Issue:5 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Deoxyuridine; DNA; Herpesviridae; Leukemia L1210; Thymidylate Synthase	1980
New approaches to chemotherapy with folate antagonists: use of leucovorin "rescue" and enzymic folate depletion. Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186 Topics: Adult; Animals; Carboxypeptidases; Carcinoma 256, Walker; Carcinoma, Squamous Cell; Deoxyuridine; Diet; Drug Combinations; Drug Synergism; Folic Acid Antagonists; Humans; Leucovorin; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Mice; Rats; Tritium	1971

Article

Year

Antiviral and antitumor activities of 5-substituted 2'-deoxyuridines.

Methods and findings in experimental and clinical pharmacology, 1980, Volume: 2, Issue:5

Topics: Animals; Antineoplastic Agents; Antiviral Agents; Deoxyuridine; DNA; Herpesviridae; Leukemia L1210; Thymidylate Synthase

1980

New approaches to chemotherapy with folate antagonists: use of leucovorin "rescue" and enzymic folate depletion.

Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186

Topics: Adult; Animals; Carboxypeptidases; Carcinoma 256, Walker; Carcinoma, Squamous Cell; Deoxyuridine; Diet; Drug Combinations; Drug Synergism; Folic Acid Antagonists; Humans; Leucovorin; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Mice; Rats; Tritium

1971

Other Studies

81 other study(ies) available for deoxyuridine and Leukemia L 1210

Article	Year
Synthesis and antiviral and cytotoxic activity of iodohydrin and iodomethoxy derivatives of 5-vinyl-2'-deoxyuridines, 2'-fluoro-2'-deoxyuridine, and uridine. Journal of medicinal chemistry, 1990, Volume: 33, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Biological Transport; Cell Survival; Chemical Phenomena; Chemistry; Deoxyuridine; In Vitro Techniques; Leukemia L1210; Leukemia P388; Mice; Tumor Cells, Cultured; Uridine; Vinyl Compounds	1990
Synthesis and biological activity of various 3'-azido and 3'-amino analogues of 5-substituted pyrimidine deoxyribonucleosides. Journal of medicinal chemistry, 1983, Volume: 26, Issue:12 Topics: Animals; Antineoplastic Agents; Deoxycytidine; Deoxycytidine Kinase; Deoxyuridine; Leukemia L1210; Mice; Sarcoma 180; Thymidine Kinase	1983
The influence of methotrexate pretreatment on 5-fluorouracil metabolism in L1210 cells. The Journal of biological chemistry, 1981, Feb-25, Volume: 256, Issue:4 Topics: Animals; Biological Transport; Deoxyuridine; Fluorouracil; Kinetics; Leucovorin; Leukemia L1210; Methotrexate; Mice; Phosphoribosyl Pyrophosphate; Purines; RNA, Neoplasm	1981
Mechanism of action of 5-nitro-2'-deoxyuridine. Journal of medicinal chemistry, 1982, Volume: 25, Issue:10 Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Cells, Cultured; Deoxyuridine; DNA; Female; Leukemia L1210; Mice; RNA; Time Factors	1982
Modulation of 1-beta-D-arabinofuranosylcytosine metabolism and cytotoxicity in L1210 cells by fluoropyrimidine pretreatment. Cancer research, 1982, Volume: 42, Issue:9 Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cell Line; Cell Survival; Clone Cells; Cytarabine; Deoxyribonucleotides; Deoxyuridine; Drug Interactions; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Leukemia L1210; Mice; Uridine	1982
Biochemical pharmacology of the lipophilic antifolate, trimetrexate. Advances in enzyme regulation, 1984, Volume: 22 Topics: Animals; Cell Line; Culture Techniques; Deoxyuridine; Drug Resistance; Folic Acid; Folic Acid Antagonists; Humans; Kinetics; Leucovorin; Leukemia L1210; Lymphocytes; Methotrexate; Mice; Mice, Inbred Strains; Quinazolines; Ribonucleotides; Thymidine; Trimetrexate	1984
Antiviral, antitumor, and thymidylate synthetase inhibition studies of 5-substituted styryl derivatives of 2'-deoxyuridine and their 5'-phosphates. Biochemical pharmacology, 1981, Mar-01, Volume: 30, Issue:5 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Deoxyuracil Nucleotides; Deoxyuridine; Kidney; Leukemia L1210; Methyltransferases; Mice; Photochemistry; Rabbits; Simplexvirus; Structure-Activity Relationship; Thymidylate Synthase; Vaccinia virus; Virus Replication	1981
Synthesis and biological properties of 2'-deoxy-5-vinyluridine and 2'deoxy-5-vinylcytidine. Nucleic acids research, 1982, Sep-11, Volume: 10, Issue:17 Topics: Animals; Antiviral Agents; Deoxycytidine; Deoxyuridine; Drug Evaluation, Preclinical; Herpesviridae Infections; Leukemia L1210; Mice; Structure-Activity Relationship	1982
Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Advances in enzyme regulation, 1984, Volume: 22 Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Antimetabolites; Deoxyuridine; DNA; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Kinetics; Leukemia L1210; Mice; Models, Chemical; Phenanthrolines; Pyrethrins; Rotenone	1984
Antitumor cell and antimetabolic effects of 5-ethyl-2'-deoxyuridine and 5'-substituted 5-ethyl-2'-deoxyuridine derivatives. Investigational new drugs, 1984, Volume: 2, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Cell Division; Cell Survival; Cells, Cultured; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Leukemia L1210; Mice; Thymidine Kinase	1984
Modulation of anti-metabolite effects. Effects of thymidine on the efficacy of the quinazoline-based thymidylate synthetase inhibitor, CB3717. Biochemical pharmacology, 1984, Oct-15, Volume: 33, Issue:20 Topics: Animals; Antimetabolites, Antineoplastic; Cells, Cultured; Deoxyuridine; Folic Acid; Leukemia L1210; Male; Methyltransferases; Mice; Mice, Inbred DBA; Quinazolines; Thymidine; Thymidylate Synthase	1984
Abnormal deoxyuridine suppression as a rapid predictor for antimetabolite chemosensitivity: correlation with in vitro tests of growth inhibition. Cancer treatment reports, 1984, Volume: 68, Issue:4 Topics: Animals; Antimetabolites, Antineoplastic; Cell Division; Cell Line; Colony-Forming Units Assay; Deoxyuridine; DNA; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Leukemia L1210; Methotrexate; Mice; Ovarian Neoplasms; Tumor Stem Cell Assay	1984
Antileukemic and immunosuppressive activity of 2-chloro-2'-deoxyadenosine. Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:7 Topics: Animals; Bone Marrow; Deoxyuridine; Drug Evaluation; Drug Evaluation, Preclinical; Immunosuppressive Agents; Isomerism; Leukemia; Leukemia L1210; Lymphoma; Mice; Radioimmunoassay	1984
Assessment of antimetabolite cytotoxicity: a comparison of clonogenic assays and tritiated deoxyuridine incorporation. European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:3 Topics: Animals; Cell Cycle; Cell Line; Cell Survival; Clone Cells; Cytarabine; Deoxyuridine; Dose-Response Relationship, Drug; Fluorouracil; Humans; Leukemia L1210; Melanoma; Methotrexate; Mice; Tritium	1983
Strategies for the measurement of the inhibitory effects of thymidine analogs on the activity of thymidylate synthase in intact murine leukemia L1210 cells. Biochimica et biophysica acta, 1984, Feb-28, Volume: 785, Issue:1-2 Topics: Animals; Deoxycytidine; Deoxyuridine; DNA; Leukemia L1210; Methyltransferases; Mice; Thymidine; Thymidylate Synthase	1984
Synthesis and biological properties of some cyclic phosphotriesters derived from 2'-deoxy-5-fluorouridine. Journal of medicinal chemistry, 1984, Volume: 27, Issue:4 Topics: Animals; Antimetabolites, Antineoplastic; Bromodeoxyuridine; Deoxycytidine; Deoxyuridine; Drug Resistance; Indicators and Reagents; Leukemia L1210; Mice; Organophosphorus Compounds; Structure-Activity Relationship; Thymidine; Thymidine Monophosphate	1984
Thymidylate synthetase-positive and -negative murine mammary FM3A carcinoma cells as a useful system for detecting thymidylate synthetase inhibitors. FEBS letters, 1984, Jul-23, Volume: 173, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Cells, Cultured; Deoxyuridine; Leukemia L1210; Mammary Neoplasms, Experimental; Methyltransferases; Mice; Thymidylate Synthase	1984
Use of uridine rescue to enhance the antitumor selectivity of 5-fluorouracil. Cancer research, 1983, Volume: 43, Issue:7 Topics: Animals; Bone Marrow; Deoxyuridine; Drug Therapy, Combination; Fluorouracil; Infusions, Parenteral; Injections, Intraperitoneal; Leukemia L1210; Male; Melanoma; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Uridine	1983
Modulation of fluoropyrimidine metabolism in L1210 cells by L-alanosine. Biochemical pharmacology, 1983, Jan-15, Volume: 32, Issue:2 Topics: Adenine; Alanine; Animals; Aspartic Acid; Cells, Cultured; Clone Cells; Deoxyuridine; Leukemia L1210; Mice; Nucleotides; Pyrimidines; Time Factors	1983
Effects of trimethoprim on leukaemic cells in vitro. British journal of haematology, 1981, Volume: 47, Issue:2 Topics: Animals; Cell Survival; Cells, Cultured; Child; Deoxyuridine; Dose-Response Relationship, Drug; Humans; Leucovorin; Leukemia L1210; Leukemia, Lymphoid; Mice; Sulfamethoxazole; Trimethoprim	1981
The intracellular mechanism of action of metoprine (DDMP). European journal of cancer, 1980, Volume: 16, Issue:12 Topics: Animals; Cell Survival; Cells, Cultured; Deoxyuridine; Dose-Response Relationship, Drug; Drug Resistance; Folic Acid Antagonists; Leucovorin; Leukemia L1210; Methotrexate; Mice; Purines; Pyrimethamine; Pyrimidines; Thymidine	1980
Role of thymidine kinase in the inhibitory activity of 5-substituted-2'-deoxyuridines on the growth of human and murine tumor cell lines. Biochemical pharmacology, 1982, Mar-15, Volume: 31, Issue:6 Topics: Animals; Antineoplastic Agents; Cell Line; Deoxyuridine; Humans; Leukemia L1210; Mice; Mutation; Neoplasms, Experimental; Phosphorylation; Thymidine Kinase	1982
Synthesis of pyridazine analogues of the naturally occurring nucleosides cytidine, uridine, deoxycytidine, and deoxyuridine. Journal of medicinal chemistry, 1982, Volume: 25, Issue:7 Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Cytidine; Deoxycytidine; Deoxyuridine; Hydrolysis; In Vitro Techniques; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Pyridazines; Pyrimidine Nucleosides; Uridine	1982
5-Substituted 2'-deoxyuridines: correlation between inhibition of tumor cell growth and inhibition of thymidine kinase and thymidylate synthetase. Biochemical pharmacology, 1982, Nov-15, Volume: 31, Issue:22 Topics: Animals; Antineoplastic Agents; Cells, Cultured; Deoxyuridine; Kinetics; Leukemia L1210; Methyltransferases; Mice; Thymidine Kinase; Thymidylate Synthase	1982
Thymidylate synthetase as target enzyme for the inhibitory activity of 5-substituted 2'-deoxyuridines on mouse leukemia L1210 cell growth. Molecular pharmacology, 1981, Volume: 19, Issue:2 Topics: Animals; Antineoplastic Agents; Cell-Free System; Cells, Cultured; Deoxyuridine; Kinetics; Leukemia L1210; Methyltransferases; Mice; Thymidylate Synthase	1981
Effects of UFT (mixed compound of tegafur and uracil) on cell kinetics and inhibition of thymidylate synthase in L1210 ascites tumor. Cancer investigation, 1995, Volume: 13, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Cycle; Deoxyuridine; Drug Combinations; Leukemia L1210; Male; Mice; Tegafur; Thymidylate Synthase; Uracil	1995
Synthesis of 5-[1-hydroxy (or methoxy)-2,2-dihaloethyl]-2'- deoxyuridines with antiviral and cytotoxic activity. Antiviral research, 1994, Volume: 24, Issue:4 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Deoxyuridine; Hydrocarbons, Halogenated; Leukemia L1210; Mice; Structure-Activity Relationship	1994
2'-Deoxy-2'-methylene derivatives of adenosine, guanosine, tubercidin, cytidine and uridine as inhibitors of L1210 cell growth in culture. Biochemical pharmacology, 1994, Jan-20, Volume: 47, Issue:2 Topics: Animals; Cell Cycle; Cell Division; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyuridine; Leukemia L1210; Ribonucleotide Reductases; Tubercidin; Tumor Cells, Cultured	1994
Incorporation of two deoxycytidine oxidation products into cellular DNA. Biochemistry and cell biology = Biochimie et biologie cellulaire, 1997, Volume: 75, Issue:4 Topics: Animals; Deoxycytidine; Deoxyuridine; DNA; DNA Damage; DNA Repair; HeLa Cells; Humans; Jurkat Cells; Leukemia L1210; Mice; Oxidation-Reduction	1997
Varying effects of deoxynucleosides on the incorporation of thymidine into the DNA of monolayer and suspension cultures. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1977, Volume: 154, Issue:4 Topics: Animals; Ascites; Bone Marrow; Bone Marrow Cells; Cell Survival; Cells, Cultured; Deoxycytidine; Deoxyuridine; DNA; HeLa Cells; Hydrogen-Ion Concentration; Leukemia L1210; Lymphocytes; Neoplasms, Experimental; Thymidine	1977
Synthesis of 5-selenium-substituted uracil derivatives. Inhibition of thymidylate synthetase by 5-hydroseleno-2'-deoxyuridylate. Journal of medicinal chemistry, 1979, Volume: 22, Issue:6 Topics: Animals; Deoxyuracil Nucleotides; Deoxyuridine; In Vitro Techniques; Lacticaseibacillus casei; Leukemia L1210; Methods; Methyltransferases; Mice; Selenium; Thymidylate Synthase; Uracil	1979
ESR of 125IUdR-labeled cells and X-irradiated cells at 4.2 K and above. Radiation research, 1979, Volume: 80, Issue:1 Topics: Animals; Cells, Cultured; Deoxyuridine; DNA; Electron Spin Resonance Spectroscopy; Free Radicals; Iodine Radioisotopes; Leukemia L1210; Mice; Radiation Dosage; Sarcoma; X-Rays	1979
Studies of the antitumor action of 5-fluorouracil (FU). Bulletin du cancer, 1979, Volume: 66, Issue:1 Topics: Animals; Antineoplastic Agents; Bone Marrow; Carcinoma 256, Walker; Colonic Neoplasms; Deoxyuridine; DNA; Drug Resistance; Fluorodeoxyuridylate; Fluorouracil; Humans; Intestine, Small; Leukemia L1210; Mice; Rats; Ribosomes	1979
Reactivation of dihydrofolate reductase inhibted by methotrexate or aminopterin. Archives of biochemistry and biophysics, 1977, Volume: 182, Issue:2 Topics: Aminopterin; Animals; Cell Line; Computers; Deoxyuridine; Dialysis; Enzyme Activation; Folic Acid Antagonists; Kinetics; Leukemia L1210; Mathematics; Methotrexate; Protein Binding; Tetrahydrofolate Dehydrogenase	1977
Effects of 5-fluorouracil on 5-fluorodeoxyuridine 5'-monophosphate and 2-deoxyuridine 5'-monophosphate pools, and DNA synthesis in solid mouse L1210 and rat Walker 256 tumors. Cancer research, 1978, Volume: 38, Issue:8 Topics: Animals; Bone Marrow; Carcinoma 256, Walker; Deoxyuracil Nucleotides; Deoxyuridine; DNA, Neoplasm; Drug Resistance; Fluorodeoxyuridylate; Fluorouracil; Intestine, Small; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Rats	1978
Radiosensitization of hypoxic tumor cells by simultaneous administration of hyperthermia and nitroimidazoles. Radiation research, 1977, Volume: 70, Issue:2 Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Survival; Deoxyuridine; Female; Hyperthermia, Induced; Hypoxia; Leukemia L1210; Metronidazole; Mice; Mice, Inbred Strains; Neoplasms; Neoplasms, Experimental; Nitroimidazoles; Radiation Tolerance; Radiation-Sensitizing Agents; Sarcoma	1977
[Correlation between the effects of cytostatic agents on leukemia L 1210 in vivo and in the short term test in vitro (author's transl)]. Blut, 1977, Jul-20, Volume: 35, Issue:1 Topics: Animals; Cell Count; Culture Techniques; Deoxyuridine; Doxorubicin; Female; Leucine; Leukemia L1210; Methotrexate; Mice; Thymidine; Time Factors; Uridine; Vinblastine	1977
In vitro biological evaluation of the R and S isomers of 1-(Tetrahydrofuran-2-yl)-5-fluorouracil. Cancer research, 1975, Volume: 35, Issue:5 Topics: Animals; Cell Division; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Fibroblasts; Fluorouracil; Furans; Isomerism; Leukemia L1210; Time Factors	1975
Synthesis, antiviral and cytotoxic activity of 2'-deoxyuridines, 2'-fluoro-2'-deoxyuridines and 2'-arabinouridines containing 5-(1-hydroxy-2-halo-2-ethoxycarbonylethyl)-, 5-(1-hydroxy-2-iodo-2- carboxyethyl)- and 5-[1-hydroxy (or methoxy)-2-iodoethyl] sub Drug design and discovery, 1992, Volume: 8, Issue:3 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Arabinofuranosyluracil; Deoxyuridine; Floxuridine; Humans; KB Cells; Leukemia L1210; Leukemia P388; Mice; Simplexvirus; Structure-Activity Relationship; Tumor Cells, Cultured	1992
Interconversion of tetrahydrofolate cofactors to dihydrofolate induced by trimetrexate after suppression of thymidylate synthase by fluorodeoxyuridine in L1210 leukemia cells. Biochemical pharmacology, 1992, Jun-23, Volume: 43, Issue:12 Topics: Animals; Computer Simulation; Deoxyuridine; DNA; Enzyme Reactivators; Floxuridine; Folic Acid; Folic Acid Antagonists; Leucovorin; Leukemia L1210; Mice; Purines; Tetrahydrofolates; Thermodynamics; Thymidylate Synthase; Time Factors; Trimetrexate; Tumor Cells, Cultured	1992
5-hexyl-2'-deoxyuridine inhibition of nucleoside transport in L1210 cells. Oncology research, 1992, Volume: 4, Issue:4-5 Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Carrier Proteins; Deoxyuridine; Formycins; Kinetics; Leukemia L1210; Membrane Proteins; Nucleoside Transport Proteins; Tumor Cells, Cultured; Uridine	1992
Synthesis and biological activity of 2'-deoxy-4'-thio pyrimidine nucleosides. Journal of medicinal chemistry, 1991, Volume: 34, Issue:8 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Cytomegalovirus; Deoxycytidine; Deoxyuridine; Humans; Leukemia L1210; Leukemia, T-Cell; Mice; Simplexvirus; Thionucleosides; Thiouridine; Thymidine; Tumor Cells, Cultured	1991
5-Hexyl-2'-deoxyuridine blocks the cytotoxic effects of 5-fluorodeoxyuridine or deoxyadenosine in leukemia L1210 cells in culture. Cancer research, 1990, Aug-01, Volume: 50, Issue:15 Topics: Animals; Antimetabolites, Antineoplastic; Cell Division; Cell Survival; Deoxyadenosines; Deoxyuridine; Dose-Response Relationship, Drug; Floxuridine; Kinetics; Leukemia L1210; Mice; Tumor Cells, Cultured	1990
Further studies on the pharmacologic effects of the 7-hydroxy catabolite of methotrexate in the L1210 murine leukemia cell. Biochemical pharmacology, 1989, Mar-01, Volume: 38, Issue:5 Topics: Animals; Deoxyuridine; Folic Acid; Folic Acid Antagonists; Formates; Leucovorin; Leukemia L1210; Methotrexate; Mice; Polyglutamic Acid; Tumor Cells, Cultured	1989
Folate-pool interconversions and inhibition of biosynthetic processes after exposure of L1210 leukemia cells to antifolates. Experimental and network thermodynamic analyses of the role of dihydrofolate polyglutamylates in antifolate action in cells. The Journal of biological chemistry, 1989, Oct-15, Volume: 264, Issue:29 Topics: Animals; Computer Simulation; Deoxyuridine; Floxuridine; Folic Acid; Folic Acid Antagonists; Formates; Leukemia L1210; Methotrexate; Mice; Purines; Pyrimidines; Quinazolines; Tetrahydrofolates; Thermodynamics; Thymidylate Synthase; Trimetrexate	1989
Synthesis of 5-[1-hydroxy(or methoxy)-2-bromo(or chloro)ethyl]-2'-deoxyuridines and related halohydrin analogues with antiviral and cytotoxic activity. Journal of medicinal chemistry, 1989, Volume: 32, Issue:5 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Deoxyuridine; Leukemia L1210; Mice; Structure-Activity Relationship; Tumor Cells, Cultured	1989
Increased thymidylate synthase in L1210 cells possessing acquired resistance to N10-propargyl-5,8-dideazafolic acid (CB3717): development, characterization, and cross-resistance studies. Cancer research, 1986, Volume: 46, Issue:6 Topics: Animals; Antineoplastic Agents; Cells, Cultured; Deoxyuridine; Drug Resistance; Floxuridine; Fluorouracil; Folic Acid; Folic Acid Antagonists; Hypoxanthine; Hypoxanthines; Kinetics; Leukemia L1210; Mice; Quinazolines; Thymidylate Synthase; Tritium	1986
Antineoplastic activity of 3'-(chloroethyl)nitrosourea analogues of 2'-deoxyuridine and 2'-deoxy-5-fluorouridine. Journal of medicinal chemistry, 1986, Volume: 29, Issue:5 Topics: Alkylation; Animals; Antineoplastic Agents; Deoxyuridine; Dideoxynucleosides; Female; Floxuridine; Leukemia L1210; Mice; Nitrosourea Compounds; Structure-Activity Relationship	1986
Inhibition of thymidylate synthase in intact L1210 cells by ara-C, daunomycin, hydroxyurea and 3,4-dihydroxybenzylamine. Anti-cancer drug design, 1987, Volume: 1, Issue:4 Topics: Animals; Cytarabine; Daunorubicin; Deoxyuridine; DNA; Dopamine; Floxuridine; Hydroxyurea; Kinetics; Leukemia L1210; Methotrexate; Thymidylate Synthase	1987
Rapid determination of thymidylate synthase activity and its inhibition in intact L1210 leukemia cells in vitro. Biochemical pharmacology, 1985, Jul-01, Volume: 34, Issue:13 Topics: Animals; Cells, Cultured; Deoxycytidine; Deoxyuridine; Dose-Response Relationship, Drug; Floxuridine; Leukemia L1210; Methotrexate; Methyltransferases; Mice; Thymidylate Synthase; Tritium	1985
Growth and DNA synthesis of folate- and methionine-depleted L1210 mouse leukemia cells in culture. Journal of nutritional science and vitaminology, 1987, Volume: 33, Issue:1 Topics: Animals; Cell Division; Cells, Cultured; Deoxyuridine; DNA; Folic Acid; Leucovorin; Leukemia L1210; Methionine; Mice	1987
Reactive 5'-substituted 2',5'-dideoxyuridine derivatives as potential inhibitors of nucleotide biosynthesis. Journal of medicinal chemistry, 1987, Volume: 30, Issue:5 Topics: Animals; Chemical Phenomena; Chemistry; Deoxyuridine; DNA; Leukemia L1210; Leukemia P388; Mice; Nucleotides; Structure-Activity Relationship; Thymidylate Synthase	1987
Enhancement of the anticancer activity of bis(2-chloroethyl)nitrosourea in mice by coadministration of 2'-deoxyuridine, 2'-deoxycytidine, or thymidine. Cancer research, 1987, Jan-15, Volume: 47, Issue:2 Topics: Animals; Carmustine; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Drug Synergism; Leukemia L1210; Melanoma, Experimental; Mice; Ribonucleosides; Thymidine	1987
Effect of the dialdehyde derivative of 5'-deoxyinosine on pyrimidine deoxyribonucleoside metabolism in L1210 cells. Biochemical pharmacology, 1985, May-15, Volume: 34, Issue:10 Topics: Animals; Cells, Cultured; DCMP Deaminase; Deoxycytidine; Deoxyuridine; Inosine; Leukemia L1210; Mice; Thymidylate Synthase	1985
Role of thymidylate synthetase in the cytostatic activity of pyrimidine nucleoside analogues. Bulletin et memoires de l'Academie royale de medecine de Belgique, 1985, Volume: 140, Issue:11 Topics: Animals; Antineoplastic Agents; Arabinofuranosyluracil; Cytarabine; Deoxycytidine; Deoxyuridine; Leukemia L1210; Mice; Pyrimidine Nucleosides; Thymidylate Synthase	1985
Inhibition of cell proliferation and dihydrofolate reductase by liposomes containing methotrexate-dimyristoylphosphatidylethanolamine derivatives and by the glycerophosphorylethanolamine analogs. Biochimica et biophysica acta, 1985, Jun-11, Volume: 816, Issue:1 Topics: Ammonium Chloride; Animals; Biological Transport; Cell Division; Chemical Phenomena; Chemistry; Deoxyuridine; DNA; Folic Acid Antagonists; In Vitro Techniques; Leukemia L1210; Liposomes; Methotrexate; Mice; Phosphatidylethanolamines; Thiamine Pyrophosphate	1985
Uracil derivatives. V. Syntheses and growth-inhibitory activity against L-1210 cells of 5-substituted 2'-deoxyuridines and orotidine derivatives. Chemical & pharmaceutical bulletin, 1985, Volume: 33, Issue:2 Topics: Animals; Antineoplastic Agents; Cell Division; Cells, Cultured; Deoxyuridine; Leukemia L1210; Mice; Uridine	1985
5-Fluorouracil and derivatives in cancer chemotherapy. 3. In vivo enhancement of antitumor activity of 5-fluorouracil (FU) and 5-fluoro-2'-deoxyuridine (FUDR). Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:12 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Chromatography, Thin Layer; Deoxycytidine; Deoxyuridine; Dialysis; Drug Synergism; Drug Therapy, Combination; Floxuridine; Fluorouracil; Leukemia L1210; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Homologous	1973
Deoxycytidine kinase. I. Distribution in normal and neoplastic tissues and interrelationships of deoxycytidine and 1-beta-D-arabinofuranosylcytosine phosphorylation. Molecular pharmacology, 1969, Volume: 5, Issue:4 Topics: Adenocarcinoma; Animals; Carcinoma, Hepatocellular; Cattle; Chick Embryo; Chromatography, Ion Exchange; Cytarabine; Cytosine Nucleotides; Deoxyuridine; Escherichia coli; Fibrosarcoma; Kinetics; Leukemia L1210; Leukemia, Experimental; Liver Neoplasms; Lymphoid Tissue; Mice; Mitosis; Neoplasms, Experimental; Nucleosides; Nucleotides; Phosphotransferases; Rats; Thymidine; Thymus Gland	1969
Cytidine 5'-triphosphate synthetase as a target for inhibition by the antitumor agent 3-deazauridine. Cancer research, 1974, Volume: 34, Issue:11 Topics: Animals; Cells, Cultured; Cytidine; Cytosine Nucleotides; Deoxycytidine; Deoxyuridine; Enzyme Inhibitors; Leukemia L1210; Ligases; Liver; Mice; Thymidine; Uracil Nucleotides; Uridine	1974
Action of camptothecin on mammalian cells in culture. Cancer research, 1972, Volume: 32, Issue:12 Topics: Animals; Camptothecin; Cell Line; Cell Survival; Cricetinae; Deoxyuridine; DNA Nucleotidyltransferases; DNA Replication; DNA, Neoplasm; Leukemia L1210; Lung; Mitosis; Neoplasms, Experimental; Phosphotransferases; RNA, Neoplasm; Thymidine Kinase; Time Factors; Tritium	1972
Continuous cancer chemotherapy: nitrosourea diffusion through implanted silicone rubber capsules. Transactions - American Society for Artificial Internal Organs, 1972, Volume: 18, Issue:0 Topics: Administration, Topical; Animals; Capsules; Carmustine; Cell Survival; Deoxyuridine; Dialysis; Diffusion; Dose-Response Relationship, Drug; In Vitro Techniques; Iodine Radioisotopes; Leukemia L1210; Life Expectancy; Male; Mice; Mice, Inbred Strains; Prognosis; Silicone Elastomers; Spectrophotometry	1972
Differential cell permeability and the basis for selective activity of methotrexate during therapy of the L1210 leukemia. Cancer research, 1973, Volume: 33, Issue:6 Topics: Animals; Cell Membrane Permeability; Deoxyuridine; DNA, Neoplasm; Injections, Intraperitoneal; Injections, Subcutaneous; Intestine, Small; Leukemia L1210; Male; Methotrexate; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Peritoneum; Tetrahydrofolate Dehydrogenase; Transplantation, Homologous; Tritium	1973
Threshold methotrexate concentration for in vivo inhibition of DNA synthesis in normal and tumorous target tissues. The Journal of clinical investigation, 1973, Volume: 52, Issue:8 Topics: Animals; Ascites; Ascitic Fluid; Bone Marrow; Deoxyuridine; Depression, Chemical; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Duodenum; Intestinal Mucosa; Leukemia L1210; Methotrexate; Mice; Thymidine; Thymine Nucleotides; Tritium	1973
The basis for the disparate sensitivity of L1210 leukemia and Walker 256 carcinoma to a new triazine folate antagonist. Cancer research, 1973, Volume: 33, Issue:11 Topics: Animals; Antineoplastic Agents; Biological Transport; Carcinoma 256, Walker; Deoxyuridine; DNA, Neoplasm; Folic Acid Antagonists; In Vitro Techniques; Leukemia L1210; Methotrexate; Mice; Rats; Tetrahydrofolate Dehydrogenase; Triazines; Tritium	1973
Interaction of thymidylate synthetase and dihydrofolate reductase enzymes in vitro and in vivo. Cancer research, 1974, Volume: 34, Issue:7 Topics: Animals; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Drug Interactions; Folic Acid; Leukemia L1210; Methotrexate; Methyltransferases; Mice; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Tritium	1974
Studies with tetrahydrohomofolate and thymidylate synthetase from amethopterin-resistant mouse leukemia cells. Biochemistry, 1968, Volume: 7, Issue:8 Topics: Animals; Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Deoxyuridine; Drug Stability; Escherichia coli; Folic Acid; Leukemia L1210; Ligases; Methotrexate; Mice; Nucleotides; Spleen; Splenic Neoplasms; Tetrahydrofolate Dehydrogenase	1968
The fate of 5-trifluoromethyl-2'-deoxyuridine in monkeys, dogs, mice, and tumor-bearing mice. Cancer research, 1969, Volume: 29, Issue:4 Topics: Adipose Tissue; Animals; Carbon Isotopes; Deoxyuridine; Dogs; Haplorhini; Injections, Intravenous; Leukemia L1210; Mice; Radiometry	1969
In vivo effects of methotrexate. Inhibition of DNA synthesis and cell death in sensitive and resistant L1210 ascites populations. Chemotherapy, 1972, Volume: 17, Issue:1 Topics: Animals; Cell Count; Cell Survival; Cells, Cultured; Deoxyuridine; Depression, Chemical; DNA Replication; DNA, Neoplasm; Drug Resistance; Female; Injections, Intraperitoneal; Iodine Isotopes; Leukemia L1210; Methotrexate; Mice; Mice, Inbred Strains; Time Factors	1972
On the biochemical mechanism of action of tetrahydrohomofolic acid. Biochemical pharmacology, 1972, Feb-15, Volume: 21, Issue:4 Topics: Animals; Carbon Isotopes; Cell Line; Deoxyuridine; Depression, Chemical; DNA; Drug Resistance; Folic Acid; Formates; Leukemia L1210; Male; Mice; Orotic Acid; Spleen; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymine; Tritium	1972
Antitumor activity of a folate-cleaving enzyme, carboxypeptidase G 1 . Cancer research, 1972, Volume: 32, Issue:10 Topics: Animals; Antineoplastic Agents; Carboxypeptidases; Carcinoma 256, Walker; Cell Division; Cell Line; Cells, Cultured; Clone Cells; Deoxyuridine; Depression, Chemical; DNA, Neoplasm; Female; Folic Acid; Folic Acid Deficiency; Humans; Injections, Intraperitoneal; Leukemia L1210; Liver; Lymphoma; Male; Mice; Mice, Inbred AKR; Mice, Inbred DBA; Mice, Inbred Strains; Neoplasms, Experimental; Rats; Sarcoma 180; Thymidine; Time Factors; Tritium	1972
Quinazoline antifolates as inhibitors of dihydrofolate reductase from human leukemia cells. Biochemical pharmacology, 1970, Volume: 19, Issue:4 Topics: Adult; Aged; Animals; Biological Transport; Cell Line; Chemical Precipitation; Chromatography; Chromatography, Gel; Deoxyuridine; DNA, Neoplasm; Female; Folic Acid Antagonists; Humans; Hydroxyapatites; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Mice; Quaternary Ammonium Compounds; Quinazolines; Spectrophotometry; Sulfates; Tetrahydrofolate Dehydrogenase; Tritium; Ultraviolet Rays	1970
Growth rate and cell kill. Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186 Topics: Animals; Cell Division; Cell Survival; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Drug Interactions; Humans; Leukemia L1210; Leukemia, Experimental; Methotrexate; Mice; Thymidine; Time Factors; Tritium; Uridine	1971
Studies with a 2,4-diamino-5-chloro-quinazoline antifolate: in vitro and invivo correlates in normal and lymphosarcoma dogs. Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186 Topics: Animals; Bone Marrow; Bone Marrow Cells; Deoxyuridine; DNA; DNA, Neoplasm; Dogs; Folic Acid Antagonists; Hydrogen-Ion Concentration; Injections, Intravenous; Leukemia L1210; Lymphoma, Non-Hodgkin; Methotrexate; Quinazolines; Thymine Nucleotides; Time Factors; Tritium	1971
Tumor cell death in vivo after administration of chemotherapeutic agents. Cancer chemotherapy reports, 1969, Volume: 53, Issue:5 Topics: Animals; Antineoplastic Agents; Deoxyuridine; Iodine Isotopes; Leukemia L1210; Methotrexate; Mice	1969
Effects of perfusion with amethopterin on L1210 leukemia cells in spin filter culture. Cancer research, 1970, Volume: 30, Issue:6 Topics: Agar; Animals; Binding Sites; Cell Count; Cell Division; Centrifugation; Clone Cells; Culture Techniques; Deoxyuridine; DNA, Neoplasm; Leukemia L1210; Methods; Methotrexate; Methylation; Mice; Perfusion; Tetrahydrofolate Dehydrogenase; Time Factors; Transferases; Tritium; Uracil Nucleotides	1970
Incorporation of iododeoxyuridine-125-I into the DNA of L1210 leukemia cells during tumor development. Cancer research, 1970, Volume: 30, Issue:1 Topics: Animals; Ascitic Fluid; Deoxyuridine; DNA, Neoplasm; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Intestinal Mucosa; Iodine; Iodine Isotopes; Leukemia L1210; Liver; Mice; Spleen	1970
Radiation effects on death and migration of tumor cells in mice. Radiation research, 1970, Volume: 43, Issue:3 Topics: Animals; Deoxyuridine; DNA, Neoplasm; Female; Iodine Isotopes; Leukemia L1210; Mice; Neoplasm Metastasis; Radiation Effects; Time Factors	1970
Inactivation by mouse serum of a tightly bound inhibitor of dihydrofolate reductase. Molecular pharmacology, 1970, Volume: 6, Issue:1 Topics: Animals; Cattle; Cells; Deoxyuridine; DNA, Neoplasm; Dogs; Female; Fetus; Folic Acid Antagonists; Horses; Humans; Immune Sera; Leukemia; Leukemia L1210; Mice; Pregnancy; Rats; Species Specificity; Temperature; Time Factors; Triazines; Tritium	1970
On the poor correlation between the inhibition by methotrexate of dihydrofolate reductase and of deoxynucleoside incorporation into DNA. Cancer research, 1968, Volume: 28, Issue:10 Topics: Animals; Deoxyuridine; DNA, Neoplasm; Folic Acid Antagonists; In Vitro Techniques; Leukemia L1210; Leukemia, Experimental; Methotrexate; Mice; Neoplasm Transplantation; Nucleosides; Nucleotides; Thymidine	1968
Spin filter culture: the propagation of mammalian cells in suspension. Science (New York, N.Y.), 1969, May-02, Volume: 164, Issue:3879 Topics: Animals; Cell Line; Culture Techniques; Deoxyuridine; Filtration; Kinetics; Leukemia L1210; Ligases; Methods; Mice; Models, Biological; Tetrahydrofolate Dehydrogenase; Thymidine	1969