Compounds > deoxyglucose
Page last updated: 2024-09-02

deoxyglucose and Insulin Resistance

deoxyglucose has been researched along with Insulin Resistance in 380 studies

Research

Studies (380)

TimeframeStudies, this research(%)All Research%
pre-199063 (16.58)18.7374
1990's86 (22.63)18.2507
2000's147 (38.68)29.6817
2010's75 (19.74)24.3611
2020's9 (2.37)2.80

Authors

AuthorsStudies
Aragonés, J; Archilla-Ortega, A; Blanco-Sinfreu, C; Camps, M; Díaz-Sáez, F; Fernández-Real, JM; Gumà, A; Hernández-Alvarez, MI; Mora, S; Moreno-Navarrete, JM; Ricart, W; Romero, M; Sebastian, D; Testar, X; Zorzano, A1
Alouffi, S; Khan, MWA1
Coward, RJ; Lay, AC1
Bao, Y; He, X; Ma, X; Shen, Y; Su, H; Wang, Y; Ying, L; Zhou, J; Zhu, W1
Ahmad, K; Choi, I; Lee, EJ; Lee, YH; Shaikh, S1
Han, JS; Jang, JH; Park, JE1
Buch, BT; Gudiksen, A; Halling, JF; Kjøbsted, R; Olsen, MA; Pilegaard, H; Ringholm, S; Wojtaszewski, JFP1
Cheng, X; Le, B; Qu, S1
MacPherson, REK; Shamshoum, H; Tsiani, E; Vlavcheski, F1
Bo, P; Fang, P; Shi, M; Wan, D; Yu, M; Zhang, L; Zhang, Z; Zhu, Y1
B Birk, J; Helle, SA; Ingemann-Hansen, T; Jensen, J; Lund, J; Rustan, AC; S Tangen, D; Stadheim, HK; T Kase, E; Thoresen, GH; Wiig, H; Wojtaszewski, JFP1
Chaudhuri, R; Fazakerley, DJ; Fisher-Wellman, KH; Hoehn, KL; James, DE; Krycer, JR; Kuncic, Z; Su, Z; Vafaee, F; Yang, JYH1
Kobayashi, S1
De Silva, N; Martínez, JA; Milagro, FI; Samblas, M1
Kawamoto, E; Kawanaka, K; Masuda, H; Ra, SG; Tamakoshi, K1
Han, X; James, DE; Jensen, TE; Kleinert, M; Parker, BL; Pham, P; Raun, SH; Richter, EA; Sylow, L1
Barrientos, G; Campos, C; Cerda-Kohler, H; Contreras-Ferrat, A; Diaz-Vegas, A; Llanos, P; Quinteros-Waltemath, O; Sánchez-Aguilera, P1
Chen, Y; Gao, K; Li, Z; Ma, L; Su, Y; Xie, Y; Xu, W1
Bertuzzi, A; Debard, C; Durand, C; Mingrone, G; Salinari, S; Vidal, H; Zimmet, P1
Alkema, W; de Vlieg, J; Dokter, WH; Fleuren, WW; Guigas, B; Linssen, MM; Ouwens, DM; Toonen, EJ; van der Zon, GC1
Chen, Y; Deng, J; Niu, P; Shi, D; Zhang, Y1
Bao, Y; Bu, L; Gao, X; Liu, Z; Qu, S; Zou, J1
Fujisaka, S; Ishibashi, H; Ishiki, M; Nishida, Y; Sasaoka, T; Takikawa, A; Tobe, K; Urakaze, M; Usui, I; Wada, T1
Baranowski, M; Blachnio-Zabielska, A; Burgess, K; Gorski, J; Hundal, HS; Lipina, C; Macrae, K; Suhm, T; Weigert, C1
Chang, HW; Hwang, SL; Hye Yang, J; Jeong, YT; Li, X; Lu, Y; Son, JK1
Fealy, CE; Flask, CA; Haus, JM; Huang, H; Kirwan, JP; Malin, SK; McCullough, AJ; Mulya, A; Pagadala, MR; Scelsi, AR1
Baranowski, M; Chabowski, A; Górski, J; Mikłosz, A; Łukaszuk, B1
Gavrilova, O; Ravussin, Y; Reitman, ML; Xiao, C1
Hayata, H; Marunaka, Y; Miyazaki, H; Niisato, N; Yokoyama, N1
Briand, F; Costard, C; Muzotte, E; Prunet-Marcassus, B; Sordello, S; Sulpice, T; Thieblemont, Q1
Chandramouli, V; Ismail-Beigi, F; Muzic, RF; Su, KH1
Cortez, CC; Gettys, TW; Orgeron, M; Stone, KP; Wanders, D1
Bo, P; Fang, P; Guo, L; Shi, M; Yu, M; Zhang, Z1
Arias, EB; Cartee, GD; Castorena, CM; Sharma, N; Wang, H1
Bao, Y; Deng, Z; Hao, Y; Hu, X; Jia, W; Luo, Y; Ma, X; Zhou, J1
Hames, KC; Jensen, MD; Johnson, ML; Lalia, AZ; Lanza, IR; Port, JD1
Chao, H; Grande, R; Harris, TE; Li, C; Li, H; Lira, V; Yan, Z1
Higashiyama, A; Hirata, T; Imano, H; Kadota, A; Kubota, Y; Miyamatsu, N; Miyamoto, Y; Nishida, Y; Nishikawa, T; Nishimura, K; Okamura, T; Sugiyama, D1
Freund, J; Hellwig, A; Hellwig, M; Henle, T; Herder, C; Hoffmann, B; Krämer, U; Luckhaus, C; Peßler, A; Roden, M; Schikowski, T; Schulte, T; Sugiri, D; Teichert, T; Vierkötter, A; Vossoughi, M1
Fukuhara, M; Hata, J; Hirakawa, Y; Hotta, T; Ikeda, F; Kang, D; Kitazono, T; Kiyohara, Y; Koga, M; Mukai, N; Nakamura, U; Ninomiya, T1
Avalos-Soriano, A; De la Cruz-Cordero, R; Duarte-Vázquez, MÁ; Garcia-Gasca, T; López-Martínez, FJ; Rosado, JL1
Cai, Q; Du, W; Gao, F; Jian, L; Lu, F; Shafqat, RA; Zafar, MI1
Booth, FW; Britton, SL; Kanaley, JA; Koch, LG; Meers, GM; Morris, ME; Padilla, J; Park, YM; Rector, RS; Thyfault, JP; Vieira-Potter, VJ; Welly, RJ; Zidon, TM1
Arias, EB; Cartee, GD; Wang, H1
Jiang, G; Liang, G; Song, X; Wang, F; Xu, H; Zhang, L; Zhou, L1
Gautam, S; Ishrat, N; Narender, T; Singh, R; Srivastava, AK; Yadav, P1
Jiang, G; Liang, G; Qian, Z; Song, X; Wang, F; Zhang, L1
Jeong, JH; Lee, H; Li, H; Noh, M; Ryu, JH1
Bu, L; Chang, X; Cheng, X; Qu, S; Sheng, C; Su, B; Yao, Q1
Andreozzi, F; Beguinot, F; Davalli, AM; Folli, F; Mannino, GC; Miele, C; Nigro, C; Procopio, T; Raciti, GA; Sesti, G1
Fisher-Wellman, KH; Gilliam, LA; Lin, CT; Neufer, PD; Reese, LR; Ryan, TE; Smith, CD; Torres, MJ1
Bhonde, RR; Shree, N1
Cheng, J; Hisatome, I; Hong, L; Hu, Y; Li, Z; Luo, C; Wen, T; Yamamoto, T; Yuan, H; Zhang, X; Zhang, Y; Zhu, Y; Zhuang, W; Zou, J1
Antoons, G; Chanda, D; Coumans, WA; Geomini, A; Glatz, JFC; Kapsokalyvas, D; Liu, Y; Luiken, JJFP; Nabben, M; Neumann, D; Schönleitner, P; Simons, PJ; Steinbusch, LKM; van Zandvoort, M1
Du, H; Friedman, TC; Liu, L; Liu, Y; Lutfy, K; Nakagawa, Y; Ren, X; Wang, W; Wang, Y1
Guo, ZJ; Hou, FF; Liang, M; Wang, GB; Zhang, X; Zhou, QG1
Chi, MM; Louden, E; Moley, KH1
Bachelard, H; Badeau, M; Bourgoin, F; Larivière, R; Mélançon, S; Nadeau, A; Pitre, M2
Bomhoff, GL; Geiger, PC; Gupte, AA1
Dong, F; Kandadi, MR; Ren, J; Sreejayan, N1
Alonso-Castro, AJ; González-Chávez, MM; Miranda-Torres, AC; Salazar-Olivo, LA1
Hommelberg, PP; Langen, RC; Mensink, RP; Plat, J; Schols, AM1
Jiao, HC; Lin, H; Song, ZG; Zhao, JP1
Asano, T; Fukui, K; Ikubo, M; Ishihara, H; Ishiki, M; Sasaoka, T; Tsuneki, H; Wada, T1
Adochio, R; Draznin, B; Kim, T; Wayne Leitner, J1
Bomhoff, GL; Geiger, PC; Gupte, AA; Swerdlow, RH1
Hokari, F; Kawanaka, K; Kawasaki, E; Koshinaka, K1
Han, DH; Hancock, C; Holloszy, JO; Jung, SR1
Li, CZ; Sha, JP; Xue, YM; Ye, XY1
Dey, CS; Gupta, A2
Kublaoui, BM; Oden, JD; Shah, S; White, PC1
Bailey, CJ; Gao, D; Griffiths, HR1
Barrett, EJ; Chong, DG; Inyard, AC; Klibanov, AL1
Bujalska, IJ; Convey, G; Gathercole, LL; Hegyi, K; Laber, D; Lavery, GG; Lenaghan, C; Mayers, R; Morgan, SA; Sethi, JK; Sherlock, M; Smith, DM; Stewart, PM; Tomlinson, JW; Yu, A1
Beck Jørgensen, S; Hewitt, K; Kemp, BE; O'Neill, HM; Steinberg, GR1
Bloch, J; Dessen, P; Duplain, H; Mathieu, C; Monney, A; Nicod, P; Sartori, C; Scherrer, U1
Bhattacharya, S; Biswas, A; Dasgupta, S; Kundu, R; Pal, BC; Roy, SS1
Aillaud, M; Asagami, T; Azuma, J; Deng, AC; Jin, H; Kundu, RK; Quertermous, T; Reaven, GM; Tsao, PS; Yue, P1
Berleze, KJ; de Assis, AM; de Souza, DO; Longoni, A; Müller, AP; Perry, ML; Rotta, LN; Schweigert, ID; Sordi, F1
Anand, S; Balakrishnan, A; Lakshmi, BS; Muthusamy, VS; Nithya, N; Sangeetha, KN; Sujatha, S; Velmurugan, D1
Blangero, J; Bozaoglu, K; Cameron-Smith, D; Carless, MA; Collier, GR; Curran, JE; Dyer, TD; Foletta, VC; Jowett, JB; Konstantopoulos, N; McAinch, AJ; Moses, EK; Prior, MJ; Segal, DH; Walder, KR1
Fujisawa, E; Hori, S; Nagira, K; Nakano, T; Saito, S; Sasaoka, T; Sugiyama, M; Tsuneki, H; Wada, T1
Iizuka, Y; Sakurai, E; Ueda, Y; Yagi, Y1
Kong, T; Li, R; Li, Y; Liu, LY; Na, LX; Sun, CH; Zhang, YL1
Berdichevsky, A; Bose, A; Guarente, L1
Díez, J; Fernández-Veledo, S; Garcia-Guerra, L; Jurado-Pueyo, M; Lorenzo, M; Mayor, F; Murga, C; Nieto-Vazquez, I; Vila-Bedmar, R; Zalba, G1
Chen, LL; Hu, X; Kong, W; Yang, WH; Yue, L; Zeng, TS; Zhang, HH; Zhang, JY; Zheng, J1
Davies, GJ; Gloster, TM; He, Y; Macauley, MS; Stubbs, KA; Vocadlo, DJ1
Ding, H; Guo, Y; Li, D; Wu, W; Zhang, J1
Cao, C; Chen, Y; Liu, G; Liu, Y; Wang, W1
Hoshino, M; Kimura, Y; Koya, D; Nakano, T; Ojima, M; Sasaoka, T; Tsuneki, H; Wada, T1
Hsu, WH; Lee, BH; Pan, TM1
Hirai, H; Kudoh, A; Satoh, H; Watanabe, T1
Hsu, WH; Lee, BH; Liao, TH; Pan, TM1
Albuquerque, RC; Campa, A; de Oliveira, EM; Filippin-Monteiro, FB; Knebel, FH; Sandri, S1
Cartee, GD; Mackrell, JG1
An, SY; Choi, SE; Ha, ES; Han, SJ; Kang, Y; Kim, DJ; Kim, HJ; Kim, TH; Lee, KW; Lee, MS1
Ashida, H; Kawabata, K; Kawasaki, K; Sawada, K; Yamamoto, N; Yamashita, T1
Chen, K; Gengler, J; Lin, L; Pang, W; Sun, Y; Tong, Q; Wang, F1
Abdulkader, F; Alves-Wagner, AB; Campello, RS; Machado, UF; Mori, RC1
Chang, WC; Shen, SC1
Bo, P; Guo, L; Li, G; Sheng, S; Shi, M; Zhang, L; Zhang, Z; Zhu, Y1
Bakhtiyari, S; Golestani, A; Gorgani-Firuzjaee, S; Meshkani, R1
Alonso-Castro, AJ; Gómez-Espinoza, G; Salazar-Olivo, LA; Zapata-Bustos, R1
Feng, SD; Hu, B; Hu, XB; Liao, DF; Ling, HY; Liu, G; Qin, L; Wen, GB; Zhong, J1
Dealtry, G; Koekemoer, T; Roux, S; van de Venter, M; Williams, S1
Bagby, GJ; Borst, SE1
Cui, TX; Horiuchi, M; Iwai, M; Nakagami, H; Shiuchi, T; Takeda-Matsubara, Y; Wu, L1
Dey, CS; Kumar, N3
Becker, C; Bonen, A; Fischer, Y; Glatz, JF; Koonen, DP; Luiken, JJ; Tandon, NN; Van Der Vusse, GJ; Willems, J; Zorzano, A1
Choi, SB; Park, S2
Itani, SI; Lodish, HF; Murrey, HE; Ruderman, NB; Saha, AK; Tomas, E; Tsao, TS; Zhang Cc, Cc1
Bashan, N; Ben-Romano, R; Klip, A; Riesenberg, K; Rudich, A; Schlaeffer, F; Török, D; Vanounou, S1
Cleasby, ME; Kelly, PA; Seckl, JR; Walker, BR1
Andrikopoulos, S; Carey, AL; Febbraio, MA; Koukoulas, I; Lamont, B; Proietto, J1
Brozinick, JT; Dohm, GL; Roberts, BR1
Ando, K; Asano, T; Fujita, T; Matsui, H; Ogihara, T; Shimosawa, T1
Anai, M; Asano, T; Fujishiro, M; Fukushima, Y; Honda, M; Inukai, K; Katagiri, H; Kikuchi, M; Ogihara, T; Oka, Y; Onishi, Y; Ono, H; Sakoda, H; Shojima, N1
Inoue, T; Kashiwabara, A; Kawasaki, T; Ogata, N; Sawashige, K; Sekino, N; Yamanouchi, T1
Andrikopoulos, S; Favaloro, J; Funkat, A; Howlett, KF; Kraegen, EW; Lamont, BJ; Proietto, J; Ye, JM; Zajac, JD1
Chen, L; Fisher, SJ; Gonzalez, FJ; Goodyear, LJ; Hirshman, MF; Jozsi, AC; Kahn, CR; Norris, AW; Ristow, M; Rosen, ED; Spiegelman, BM; Szanto, I1
Häring, HU; Kausch, C; Krützfeldt, J; Matthaei, S; Staiger, H; Staiger, K; Stumvoll, M1
Henriksen, EJ; Lailerd, N; Saengsirisuwan, V; Sloniger, JA; Toskulkao, C1
Huang, Y; Ishizawa, M; Ishizuka, T; Kajita, K; Kawai, Y; Miura, A; Morita, H; Natsume, Y; Uno, Y; Yamamoto, Y; Yasuda, K1
Cooksey, RC; Gulve, EA; Hazel, M; Jones, D; McClain, DA; Neidigh, JL; Parker, G; Witherbee, B1
Dey, CS; Ishrath, A; Kaul, CL; Kumar, N1
Cline, GW; Davies, PJ; Leibowitz, MD; Shen, Q; Shulman, GI1
Bosch, RR; Hermus, AR; Olthaar, AJ; Pouwels, MJ; Span, PN; Sweep, CG; Tack, CJ1
Cui, TX; Horiuchi, M; Iwai, M; Li, HS; Li, JM; Min, LJ; Okumura, M; Shiuchi, T; Wu, L1
Ahrén, B; Pacini, G; Sundler, F; Wierup, N; Wynick, D1
Kimura, M; Shibasaki, T; Shiota, T; Suzuki, M; Tateishi, N; Yamauchi, H; Yoshie, F1
Adams, SH; Brown, NF; Commerford, SR; Corkey, BE; O'Doherty, RM; Perdomo, G; Richard, AM1
Lerch, R; Montessuit, C; Papageorgiou, I; Rosenblatt-Velin, N1
Befroy, D; Bilz, S; Elder, BD; Liu, ZX; Qu, X; Romanelli, AJ; Samuel, VT; Shulman, GI1
Bashan, N; Ben-Romano, R; Potashnik, R; Riesenberg, K; Rudich, A; Sasaoka, T; Schlaeffer, F; Tirosh, A1
Bailey, CJ; Turner, SL1
Barrett, EJ; Clark, MG; Rattigan, S; Richards, SM; Wheatley, CM1
Demarest, KT; Nelson, E; Olefsky, JM; Osborne, M; Wilkes, JJ1
Abaffy, T; Cooper, GJ1
Bellis, A; Condorelli, G; Marrone, C; Morisco, C; Sadoshima, J; Trimarco, B; Trimarco, V1
Asano, T; Fukui, K; Funaki, M; Ishihara, H; Kawahara, J; Kobayashi, M; Murakami, S; Sasaoka, T; Wada, T1
Crackower, M; Eweida, M; Giacca, A; Jefferies, C; Kahn, CR; Klip, A; Konrad, D; Liadis, N; Mak, TW; Suzuki, A; Wijesekara, N; Woo, M1
Tian, R1
Boucher, J; Boutin, JA; Carpéné, C; Ferry, G; Grès, S; Guigné, C; Pradères, JP; Prévot, D; Quilliot, D; Saulnier-Blache, JS; Simon, MF; Valet, P1
Eguchi, T; Hayashi, M; Hirao, K; Hirose, H; Kanno, Y; Kawabe, H; Maruyama, T; Morii, T; Ogata, T; Ohno, Y; Saito, I; Saruta, T1
Choi, GH; Choi, HI; Jung, CY; Lee, W; Park, SY; Ryu, J2
Beil, M; Deacon, R; Gao, J; Gounarides, J; Korach-André, M; Laurent, D; Sun, D1
Borst, SE; Conover, CF1
Lee, W; Park, SY; Ryu, J1
Babendure, JL; Chi, NW; Dahiyat, BI; Favelyukis, S; Imamura, T; Nguyen, MT; Olefsky, JM; Satoh, H; Sbodio, JI; Zalevsky, J1
Brown, JM; Chung, S; Hopkins, R; McIntosh, MK; Provo, JN1
Baxter, RC; Chan, SS; Firth, SM; Twigg, SM1
Doh, KO; Jeon, JR; Jeong, JH; Kim, JY; Kim, YW; Lee, SK; Park, JO; Park, SY1
Hruz, PW; Yan, Q1
Abramczyk, M; Borowska, M; Dworacka, M; Kuczynski, S; Szczawinska, K; Winiarska, H1
Lonovics, J; Németh, J; Peitl, B; Porszasz, R; Sári, R; Sziklai, I; Szilvássy, J; Szilvássy, Z1
Bilan, PJ; Caldwell, JS; Ilany, J; Kahn, CR; Kapur, S; Marette, A; Patti, ME1
Gautier, N; Hinault, C; Mothe-Satney, I; Van Obberghen, E1
Good, M; Haupt, LM; Hutley, LJ; Newell, FM; Prins, JB; Whitehead, JP1
Hashimoto, H; Ide, T; Kadowaki, T; Kamei, N; Kobayashi, M; Kubota, N; Kumagai, K; Manabe, I; Murakami, K; Nagai, R; Nishimura, S; Ogata, H; Ohnishi, Y; Ohsugi, M; Ohtsuka-Kowatari, N; Oishi, Y; Sakamoto, K; Suzuki, R; Tobe, K; Tokuyama, K; Tsunoda, M; Ueki, K; Watanabe, T; Yamauchi, T1
Geiger, PC; Han, DH; Holloszy, JO; Wright, DC1
Basile, R; Green, A; Rumberger, JM1
Darby, I; Febbraio, MA; Lancaster, GI; Turpin, SM; Watt, MJ1
Muraki, K; Okuya, S; Tanizawa, Y1
Okahata, S; Terauchi, Y; Tobe, K1
Febbraio, MA; Pinnamaneni, SK; Southgate, RJ; Watt, MJ1
Bandyopadhyay, A; Bhattacharya, S; Biswas, T; Dey, D; Giri, BB; Mandal, SK; Pal, BC; Roy, SS1
Litherland, GJ; Morris, NJ; Walker, M; Yeaman, SJ1
Briat, A; Demongeot, J; Fagret, D; Ghezzi, C; Halimi, S; Perret, P; Slimani, L; Villemain, D2
Bouzakri, K; Zierath, JR1
Proctor, SD; Russell, JC1
An, J; Catlin, RL; Cline, GW; Coleman, RA; Liu, ZX; Nagle, CA; Newgard, CB; Shiota, M; Shulman, GI; Torres, TP; Wang, S1
Qian, Z; Sun, S; Xi, L; Xu, G; Zhou, C1
Bass, J; Ramos, RR; Swanson, AJ1
Gao, Z; Liu, D; Liu, Z; Ye, J; Yin, J1
Bansal, DD; Boparai, RK; Chaudhary, DP1
Hruz, PW; Jay, PY; Struthers, H; Yan, Q1
Cong, W; Liu, Q; Tao, R; Tian, J; Ye, F1
Bobkiewicz-Kozłowska, T; Dworacka, M; Wegner, M; Winiarska, H1
Agudo, J; Andersson, CX; Bosch, F; Elias, I; Ferré, T; Franckhauser, S; Nagaev, I; Rotter Sopasakis, V; Ruberte, J; Smith, U1
Alonso-Castro, AJ; Salazar-Olivo, LA1
Craig, JW; Elders, MJ; Larner, J; Locker, EF; Widom, B1
Hyslop, PA; Kuhn, CE; Sauerheber, RD1
De Pirro, R; Goldfine, ID; Rossetti, L; Roth, RA1
Grunfeld, C1
Dean, H; Friesen, HG; Haworth, JC; Imai, Y; Tokuhiro, E; Winter, J1
Kanatsuna, T; Kondo, M; Nakamura, Y1
Mercer, SW; Trayhurn, P1
Bray, GA; Chan, TM; Ohshima, K; Shargill, NS1
Burant, CF; Buse, MG; Lemmon, SK; Treutelaar, MK1
Berhanu, P; Olefsky, JM; Tsai, P1
Grunfeld, C; Harrison, LC; Kahn, CR; Karlsson, A; Muggeo, M; Van Obberghen, E1
Grundleger, ML; Thenen, SW1
Bennett, PH; Fields, RM; Hidaka, H; Howard, BV; Ishibashi, F1
Crettaz, M; Jeanrenaud, B; Prentki, M; Zaninetti, D1
Godbole, VY; Grundleger, ML; Thenen, SW1
Olefsky, JM3
Iwasaki, M; Kobayashi, M; Morihara, K; Ohgaku, S; Oka, T; Shigeta, Y1
Baird, K; Grunfeld, C; Kahn, CR; Van Obberghen, E1
Ferré, P; Girard, JR; Leturque, A; Satabin, P1
Booth, FW; Nicholson, WF; Seider, MJ1
Etgen, GJ; Ivy, JL; Kang, HY; Torgan, CE1
Benecke, H; Flier, JS; Hamann, A; Le Marchand-Brustel, Y; Lowell, BB; Susulic, VS1
Haaparanta, M; Jula, A; Knuuti, MJ; Koivisto, VA; Laine, H; Luotolahti, M; Mäki, M; Nuutila, P; Ruotsalainen, U; Solin, O1
Haber, RS; Paquin, T; Pritsker, A; Weinstein, SP1
Assan, R; Burcelin, R; Eddouks, M; Girard, J; Kande, J; Maury, J1
Azevedo, JL; Carey, JO; Dohm, GL; Morris, PG; Pories, WJ2
Cusin, I; Ferrannini, E; Ganten, D; Jeanrenaud, B; Rohner-Jeanrenaud, F; Vettor, R1
Dolnikoff, MS; Hell, NS; Kettelhut, IC; Lima, FB; Marmo, MR; Matsushita, DM1
Assimacopoulos-Jeannet, F; Bobbioni-Harsch, E; Jeanrenaud, B1
Cipolla Neto, J; Dolnikoff, MS; Hell, NS; Lima, FB; Matsushita, DH; Okamoto, MM1
Bergman, J; Knuuti, MJ; Lindholm, P; Minn, H; Nuutila, P; Ruotsalainen, U; Teräs, M1
Hardy, RW; Hunnicutt, JW; McDonald, JM; Williford, J1
Buchanan, TA; Kim, JK; Youn, JH1
Bistrian, BR; Istfan, NW; Ling, PR; Mendez, B1
Caterson, ID; Cooney, GJ; Steinbeck, KS1
Ben-Ishay, D; Bursztyn, M; Mekler, J; Raz, I1
Björntorp, P; Holmäng, A; Kumagai, S1
Daimon, M; Fukase, N; Igarashi, M; Ogawa, A; Ohnuma, H; Sasaki, H; Tominaga, M; Yamatani, K1
Henriksen, EJ; Kirby, CR; Munoz, KA; Stump, CS; Tischler, ME; Woodman, CR1
Eto, M; Makino, I; Takahashi, M1
Andrews, GC; Contillo, LG; Kreutter, DK; Orena, SJ; Stevenson, RW; Torchia, AJ1
Haber, RS; Holand, A; O'Boyle, E; Weinstein, SP1
Budohoski, L; Czarnowski, D; Górski, J; Kaciuba-Uściłko, H; Langfort, J; Nazar, K1
Aerts, L; Holemans, K; Van Assche, FA; Van Bree, R; Verhaeghe, J1
Balks, HJ; Burchert, W; Hundeshagen, H; Meyer, GJ; Müller, MJ; Radoch, E; Selberg, O; vd Hoff, J1
Bergman, J; Eronen, E; Haaparanta, M; Knuuti, J; Koivisto, VA; Nuutila, P; Ruotsalainen, U; Teräs, M; Viikari, J; Voipio-Pulkki, LM1
Bouch, C; Davidson, MB; Lim, J; Marciano, D; Venkatesan, N1
Iida, H; Kirvelä, O; Knuuti, J; Laine, H; Mäkimattila, S; Nuutila, P; Pitkänen, OP; Raitakari, M; Ruotsalainen, U; Takala, T; Utriainen, T; Yki-Järvinen, H1
Kim, JK; Wi, JK; Youn, JH1
Fujiwara, R; Nakai, T1
Damrau-Abney, A; David, TS; Elmendorf, JS; Smith, TR; Turinsky, J1
Haaparanta, M; Knuuti, MJ; Laine, H; Malminiemi, K; Nuutila, P; Oikonen, V; Ruotsalainen, U1
Daniels, MC; Hämäläinen, S; McClain, D; Utriainen, T; Virkamäki, A; Yki-Järvinen, H1
Bashan, N; Kozlovsky, N; Potashnik, R; Rudich, A1
Cusin, I; Fabris, R; Federspil, G; Jeanrenaud, B; Lombardi, AM; Pagano, C; Rohner-Jeanrenaud, F; Vettor, R1
Ahmad, F; Azevedo, JL; Cortright, R; Dohm, GL; Goldstein, BJ1
da Costa Lima, NK; dos Santos, EA; Heimann, JC; Hell, NS; Lima, FB; Matsushita, DH; Okamoto, MM1
Fogt, DL; Henriksen, EJ; Hokama, JY; Jacob, S; Streeper, RS; Tritschler, HJ1
Ishizawa, M; Ishizuka, T; Itaya, S; Kajita, K; Kanoh, Y; Miura, A; Murase, H; Nagashima, T; Yamamoto, M; Yasuda, K1
Furler, SM; Kraegen, EW; Oakes, ND; Watkinson, AL1
Hardy, RW; Van Epps-Fung, M; Wells, A; Williford, J1
Burcelin, R; Charron, MJ; Factor, SM; Geenen, DL; Houseknecht, K; Katz, EB; Li, J; Stenbit, AE; Tsao, TS1
Han, DH; Hansen, PA; Holloszy, JO; Host, HH1
Chen, M; Han, DH; Hansen, PA; Holloszy, JO; Nolte, LA1
Attie, AD; Cartee, GD; Dumke, C; Ranheim, T; Schueler, KL1
Mann, GE; Sobrevia, L; Yudilevich, DL1
Damrau-Abney, A; Loegering, DJ; Turinsky, J1
Bar-Tana, J; Dolphin, PJ; Graham, SE; Lau, DC; Richardson, M; Russell, JC; Shillabeer, G; Wenzel, LM1
Chi, MM; Heimberg, H; Hresko, RC; Mueckler, M1
Ahrén, B; Simonsson, E1
Crist, GH; Lang, CH; Lanoue, KF; Xu, B1
Ikemoto, T; Ishikawa, Y; Saito, MN; Takeno, H; Tani, T; Watanabe, K1
Bailey, CJ; Jefferson, WH; Thomas, CR; Turner, SL1
Berger, J; Doebber, T; Li, Z; McCrary, C; Moller, DE; Ryder, JW; Ventre, J; Woods, J; Wu, M; Zhang, B; Zierath, JR1
Dornhorst, A; Frost, GS; Keogh, BE; Leeds, AR; Smith, D1
Gumà, A; Muñoz, P; Palacín, M; Sevilla, L; Testar, X; Zorzano, A1
Appleby, GJ; Clark, MG; Penschow, JD; Wallis, MG; Youd, JM1
Bergemann, C; Hamann, A; Kausch, C; Matthaei, S1
Bassetto, F; Fabris, R; Federspil, G; Girard, J; Leturque, A; Lombardi, AM; Serra, R; Vettor, R1
Barucci, N; Bell, K; Cline, GW; Goodyear, LJ; Griffin, ME; Kraegen, EW; Lee, D; Marcucci, MJ; Shulman, GI; White, MF1
Dietze, GJ; Fogt, DL; Henriksen, EJ; Jacob, S1
Bohov, P; Gasperíková, D; Klimes, I; Líska, B; Mitková, A; Seböková, E; Stanek, J; Ukropec, J1
Brindley, DN; Hanna, AN; Mei, J; Wang, CN; Xu, J1
Döppler, H; Müller, G; Pfizenmaier, K; Storz, P; Wernig, A1
Akanuma, Y1
Colangelo, V; Di Grezia, R; Lembo, G; Morisco, C; Orzi, F1
Choi, WS; Heart, E; Sung, CK1
Cheng, JT; Chi, TC; Liu, IM1
Fischer, BM; Frevert, EU; Kahn, BB; Kamatkar, S; Kim, YB; Neel, BG; Venable, CL1
Dylla, SJ; Hardy, RW; Williams, JP; Williford, J1
Hruz, PW; Mueckler, M; Murata, H1
Bøtker, HE; Bøttcher, M; Christiansen, JS; Gjedde, A; Nielsen, TT; Schmitz, O; Wiggers, H1
Ishizawa, M; Ishizuka, T; Kajita, K; Kanoh, Y; Miura, A; Yasuda, K1
Bell, PA; Loskutoff, DJ; Pandey, M; Samad, F1
Clark, MG; Rattigan, S; Youd, JM1
Ferguson, K; Han, DH; Hansen, PA; Holloszy, JO; Kim, JY; Nolte, LA; Thompson, PA1
Arbour-Reily, P; Floyd, ZE; Stephens, JM; Waite, KJ1
Donnelly, R; Gray, S; Idris, I; Patiag, D; Qu, X; Seale, JP; Wilkes, M1
Kahn, CR; Kulkarni, RN; Mauvais-Jarvis, F; Michael, MD; Virkamaki, A; Winnay, JN; Zisman, A1
Aitman, TJ; Collison, M; Connell, JM; Dominiczak, AF; Dominiczak, MH; Glazier, AM; Gould, GW; Graham, D; Morton, JJ1
Campbell, IW; Collison, M; Connell, JM; Dominiczak, AF; Gould, GW; Lyall, H; Salt, IP1
Adachi, T; Arakawa, K; Ikezawa, K; Kano-Ishihara, T; Matsumoto, T; Oku, A; Saito, A; Tsuda, K; Ueta, K; Yasuda, K1
Fantus, IG; Goldstein, BJ; Lai, R; Le-Tien, H; Shin, P; Tang, S1
Anai, M; Ando, K; Asano, T; Chiba, Y; Fujishiro, M; Fujita, T; Fukushima, Y; Inukai, K; Kikuchi, M; Ogihara, T; Onishi, Y; Ono, H; Sakoda, H; Sekine, N; Shojima, N1
Castellani, LW; Goto, AM; Lusis, AJ1
Ishizawa, M; Ishizuka, T; Kajita, K; Kanoh, Y; Kimura, M; Miura, A; Muto, N; Yasuda, K1
Bailey, CJ; Bates, SH; Jones, RB; Turner, SL1
Ali, SS; Sowers, JR; Walsh, MF1
Haruta, T; Ishibashi, O; Iwata, M; Kawahara, J; Kobayashi, M; Sasaoka, T; Takano, A; Takata, Y; Ueno, E; Uno, T; Usui, I1
Burén, J; Enerbäck, S; Eriksson, JW; Nilsson, E; Samuelsson, L; Yu, ZW1
Bartolomei, MS; Birnbaum, MJ; Cho, H; Chu, Q; Crenshaw, EB; Kaestner, KH; Kim, JK; Mu, J; Shulman, GI; Thorvaldsen, JL1
Asselin, G; Jacques, H; Lavigne, C; Marette, A; Tremblay, F1
Chiozzi, P; Di Virgilio, F; Fellin, R; Fioretto, P; Passaro, A; Solini, A1
Abe, T; Eguchi, K; Fujita, N; Kato, C; Kawasaki, E; Kuwahara, H; Ozaki, M; Sera, Y; Takino, H; Uotani, S; Yamaguchi, Y; Yamakawa, K; Yamasaki, H; Yamauchi, MD1
Haruta, T; Iwata, M; Kawahara, J; Kobayashi, M; Sasaoka, T; Takano, A; Ueno, E; Uno, T; Usui, I1
Henriksen, EJ; Jacob, S; Kinnick, TR; Krekler, M; Teachey, MK1
Ebina, Y; Houchi, H; Ishizawa, K; Kishi, K; Minakuchi, K; Nakaya, Y; Takishita, E; Tamaki, T; Tsuchiya, K; Yoshizumi, M1
Li, C; Shu, C; Zhang, S1
Borst, SE; Hennessy, M1
Daimon, M; Hirata, A; Igarashi, M; Kato, T; Ohnuma, H; Tominaga, M; Tsuchiya, H; Yamaguchi, H1
Fielding, G; Hay, J; Hutley, L; MacDonald, G; Prins, J; Russell, A; Stolic, M; Whitehead, J1
Ingram, DK; Lane, MA; Roth, GS1
Christ, CY; Garcia-Macedo, R; Hancock, J; Hunt, D; Ivy, JL; Mandarino, LJ1
Bosch, F; Casellas, A; Franckhauser, S; Muñoz, S; Otaegui, P; Pujol, A; Riu, E; Su, B1
Heart, E; Sung, CK1
Bleasdale, JE; Larsen, SD; Liljebris, C; Ogg, D; Palazuk, BJ1
Yoshimura, H1
Choi, YO; Jang, YJ; Kim, C; Leem, CH; Park, CS; Ryu, HJ1
Abe, M; Anai, M; Ando, K; Asano, T; Fujishiro, M; Fujita, T; Fukushima, Y; Kikuchi, M; Ogihara, T; Onishi, Y; Ono, H; Sakoda, H; Shojima, N1
Freychet, P; Le Marchand-Brustel, Y2
Elders, J; Fiser, RH; Given, BD; Hintz, RL; Horner, JA; Kobayashi, M; Mako, ME; Olefsky, JM; Rubenstein, AH; Schedwie, HK1
Freychet, R; Le Marchand-Brustel, Y1
Freychet, P; Fried, SK; Lavau, M; Susini, C1
Frayn, KN; Freychet, P; Le Marchand-Brustel, Y1
Livingston, JN; Lockwood, DH; Purvis, BJ1
Davidson, MB1
Czech, MP1
Lang, CH1
Cama, A; Quon, MJ; Taylor, SI1
Björntorp, P; Holmäng, A2
Brozinick, JT; Etgen, GJ; Ivy, JL; Yaspelkis, BB1
Cusin, I; Del Prato, S; Jeanrenaud, B; Lisato, G; Tiengo, A1
Doyle, P; Jeanrenaud, B; Zarjevski, N1
Haber, RS; Weinstein, SP1
Brichard, SM; Henquin, JC; Ongemba, LN1
Byyny, RL; Draznin, B; Lloyd, S; LoVerde, M; Mitchell, W1
Asskamp, B; Eckel, J; Reinauer, H1
Hashimoto, N; Makino, H; Mimura, M; Nozaki, O; Onaya, T; Shimada, F; Suzuki, Y; Taira, M; Tawata, M; Yoshida, S1
Creutzfeldt, W; Hartmann, H; Meyer-Alber, A; Stümpel, F1
Adams, HB; Chen, KS; Heydrick, SJ; Kurowski, TG; Ruderman, NB1
Hager, SR; Jochen, AL; Kalkhoff, RK1
Chattaway, JA; Elliott, KR; Smith, SA1
Andrews, KM; Gibbs, EM; Hutson, NJ; Kreutter, DK; Stevenson, RW1
Assimacopoulos-Jeannet, F; Cusin, I; Jeanrenaud, B; Rohner-Jeanrenaud, F; Terrettaz, J; Zarjevski, N1
Chisholm, DJ; Jenkins, AB; Kraegen, EW; Storlien, LH1
Adamo, M; Draznin, B; Garvey, WT; Houlder, N; LeRoith, D; Lewis, D; Sherman, N; Sussman, K1
Marshall, S; Traxinger, RR1
Chisholm, DJ; James, DE; Jenkins, AB; Kraegen, EW; Storlien, LH1
Akanuma, H; Aoyagi, T; Kobayashi, T; Sakaguchi, T; Umezawa, H; Wada, T1
Beemer, FA; Klinkhamer, MP; Krans, HM; Lindhout, D; Maassen, JA; Möller, W; Sips, H; van der Zon, GC1
Cascieri, MA; Chicchi, GG; Hayes, NS; Strader, CD1
Arsenis, G; Livingston, JN1
Almira, EC; Alvarez, IM; Caro, JF; Dohm, GL; Green, A; Misbin, RI1
Fujiwara, T; Horikoshi, H; Ushiyama, I; Yoshioka, S; Yoshioka, T1
Ishibashi, O; Kitamura, E; Kobayashi, M; Maegawa, H; Shigeta, Y; Takata, Y; Watanabe, N1
Luttrell, L; Rogol, AD1
Astbury, LD; Caterson, ID; Cooney, GJ; Williams, PF1
Draznin, B; Eckel, RH; Kao, M; Sherman, NA; Sussman, KE; Yost, T1
Klinkhamer, MP; Krans, HM; Maassen, JA; Möller, W; Odink, RJ; Sips, H; van der Zon, GC; Wieringa, T1
Turinsky, J2
Hayes, GR; Lockwood, DH; Truglia, JA1
Atkinson, SM; Caro, JF; Dabbs, DJ; Dohm, GL; Elton, CW; Flickinger, EG; Fushiki, T; Meelheim, D; Pories, WJ; Tapscott, EB1
Peters, EJ; Prince, MJ; Smith, FE; Stuart, CA1
Given, BD; Iwo, K; Kondo, M; Miyamura, K; Miyano, M; Nanjo, K; Nishimura, S; Okai, K; Sanke, T; Sowa, R1
Garvey, WT; Marshall, S; Olefsky, JM1
Burleigh, KM; Chisholm, DJ; James, DE; Kraegen, EW; Storlien, LH1
Fletcher, HP; Skillman, CA1
Garvey, WT; Marshall, S; Matthaei, S; Olefsky, JM1
Craig, BW; Garthwaite, SM; Holloszy, JO1
Capeau, J; Caron, M; Cherqui, G; Lascols, O; Picard, J; Wicek, D1
Gherzi, R; Rosen, OM; Russell, DS; Taylor, SI1
Craig, BW; Treadway, J1
Larkins, RG; Veroni, MC1
Grunfeld, C; Jones, DS; Shigenaga, JK1
Krans, HM; Van Putten, JP; Wieringa, T1
Augert, G; Le Marchand-Brustel, Y; Van de Werve, G1

Reviews

9 review(s) available for deoxyglucose and Insulin Resistance

ArticleYear
Dicarbonyls Generation, Toxicities, Detoxifications and Potential Roles in Diabetes Complications.
    Current protein & peptide science, 2020, Volume: 21, Issue:9

    Topics: Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Insulin; Insulin Resistance; Isoenzymes; Lactoylglutathione Lyase; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Signal Transduction

2020
Consequences of Dicarbonyl Stress on Skeletal Muscle Proteins in Type 2 Diabetes.
    Current protein & peptide science, 2020, Volume: 21, Issue:9

    Topics: Deoxyglucose; Diabetes Mellitus, Type 2; Extracellular Matrix Proteins; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Insulin; Insulin Resistance; Isoenzymes; Lactoylglutathione Lyase; Muscle, Skeletal; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Signal Transduction

2020
[Pharmacological Mechanisms of Boiogito and Bofutsushosan in Diabetes and Obesity Models].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2018, Volume: 138, Issue:3

    Topics: Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Drugs, Chinese Herbal; Gardenia; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Mice; Muscle, Skeletal; NF-kappa B; Obesity; Phytotherapy; Stephania; Streptozocin; Tumor Necrosis Factor-alpha

2018
[Postprandial hyperglycemia].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Sep-28, Volume: Suppl 3

    Topics: Arteriosclerosis; Biomarkers; Deoxyglucose; Diabetes Mellitus, Type 2; Endothelium, Vascular; Evidence-Based Medicine; Glucose; Hyperglycemia; Hyperthyroidism; Insulin; Insulin Resistance; Insulin Secretion; Liver Cirrhosis; Oxidative Stress; Postprandial Period

2006
LIlly lecture 1980. Insulin resistance and insulin action. An in vitro and in vivo perspective.
    Diabetes, 1981, Volume: 30, Issue:2

    Topics: Adipose Tissue; Adult; Animals; Blood Glucose; Child, Preschool; Deoxyglucose; Diabetes Mellitus; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Insulin; Insulin Antagonists; Insulin Resistance; Islets of Langerhans; Liver; Monocytes; Obesity; Proinsulin; Receptor, Insulin; Spermine; Sulfonylurea Compounds

1981
[Physiopathology and therapy of diabetes mellitus].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1999, Sep-10, Volume: 88, Issue:9

    Topics: Animals; Arteriosclerosis; Biomarkers; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Humans; Insulin Resistance; Obesity; Patient Education as Topic

1999
Caloric restriction in primates and relevance to humans.
    Annals of the New York Academy of Sciences, 2001, Volume: 928

    Topics: Aging; Animals; Biomarkers; Blood Glucose; Body Temperature; Cardiovascular Diseases; Deoxyglucose; Diabetes Mellitus; Diet, Reducing; Drug Evaluation, Preclinical; Energy Intake; Energy Metabolism; Food Deprivation; Garcinia; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Longevity; Macaca mulatta; Medicine, Ayurvedic; Metformin; Neoplasms; Phytotherapy; Plant Preparations; Primates; Rats; Rats, Inbred F344; Saimiri; Saponins; Triterpenes

2001
The insulin receptor: its role in insulin resistance of obesity and diabetes.
    Diabetes, 1976, Volume: 25, Issue:12

    Topics: Adipose Tissue; Adult; Animals; Child; Deoxyglucose; Diabetes Mellitus; Dose-Response Relationship, Drug; Humans; Insulin; Insulin Resistance; Obesity; Protein Binding; Receptor, Insulin

1976
Tracer studies of in vivo insulin action and glucose metabolism in individual peripheral tissues.
    Hormone and metabolic research. Supplement series, 1990, Volume: 24

    Topics: Animals; Carbon Radioisotopes; Deoxyglucose; Glucose; Insulin; Insulin Resistance; Models, Biological; Muscles; Radioisotope Dilution Technique; Tritium

1990

Trials

5 trial(s) available for deoxyglucose and Insulin Resistance

ArticleYear
Effects of Dietary n-3 Fatty Acids on Hepatic and Peripheral Insulin Sensitivity in Insulin-Resistant Humans.
    Diabetes care, 2015, Volume: 38, Issue:7

    Topics: Adult; Antimetabolites; Blood Glucose; Deoxyglucose; Docosahexaenoic Acids; Double-Blind Method; Eicosapentaenoic Acid; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin, Regular, Human; Liver; Male; Meals; Mitochondria, Muscle; Postprandial Period

2015
Usefulness of troglitazone administration to obese hyperglycaemic patients with near-normoglycaemia.
    Diabetes, obesity & metabolism, 2003, Volume: 5, Issue:3

    Topics: Adult; Aged; Blood Glucose; Chromans; Deoxyglucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Male; Middle Aged; Obesity; Thiazoles; Thiazolidinediones; Troglitazone

2003
Disproportionately elevated proinsulin levels in type 2 diabetic patients treated with sulfonylurea.
    International journal of clinical pharmacology and therapeutics, 2006, Volume: 44, Issue:1

    Topics: Aged; Blood Glucose; Body Mass Index; C-Peptide; Caloric Restriction; Deoxyglucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fasting; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Multivariate Analysis; Patient Selection; Proinsulin; Sulfonylurea Compounds

2006
Role of blood flow in regulating insulin-stimulated glucose uptake in humans. Studies using bradykinin, [15O]water, and [18F]fluoro-deoxy-glucose and positron emission tomography.
    The Journal of clinical investigation, 1996, Apr-01, Volume: 97, Issue:7

    Topics: Adult; Biological Transport, Active; Bradykinin; Deoxyglucose; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glucose; Hemodynamics; Humans; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Oxygen Radioisotopes; Tomography, Emission-Computed; Vasodilation

1996
Acute effects of celiprolol on muscle blood flow and insulin sensitivity: studies using [15O]-water, [18F]-fluorodeoxyglucose and positron emission tomography.
    European journal of clinical pharmacology, 1997, Volume: 52, Issue:1

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Adult; Celiprolol; Cross-Over Studies; Deoxyglucose; Double-Blind Method; Drug Evaluation; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Insulin Resistance; Male; Muscle, Skeletal; Oxygen Radioisotopes; Regional Blood Flow; Tomography, Emission-Computed; Vasodilator Agents; Water

1997

Other Studies

366 other study(ies) available for deoxyglucose and Insulin Resistance

ArticleYear
Neuregulin 4 Downregulation Induces Insulin Resistance in 3T3-L1 Adipocytes through Inflammation and Autophagic Degradation of GLUT4 Vesicles.
    International journal of molecular sciences, 2021, Nov-30, Volume: 22, Issue:23

    Topics: 3T3 Cells; Adipocytes; Animals; Autophagy; Cell Line; Cystinyl Aminopeptidase; Cytokines; Deoxyglucose; Down-Regulation; Glucose Transporter Type 4; GTPase-Activating Proteins; Inflammation; Insulin; Insulin Resistance; Mice; Neuregulins; Qa-SNARE Proteins; Receptor, Insulin; RNA Interference; RNA, Small Interfering

2021
An In Vitro Method to Analyze Glucose Uptake in Podocytes.
    Methods in molecular biology (Clifton, N.J.), 2020, Volume: 2067

    Topics: Cell Culture Techniques; Cell Line; Deoxyglucose; Diabetic Nephropathies; Feasibility Studies; Glucose; Humans; Insulin; Insulin Resistance; Podocytes; Tritium

2020
1,5-Anhydroglucitol × glycated hemoglobin A
    Acta diabetologica, 2020, Volume: 57, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Blood Glucose; China; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Glucose Intolerance; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Islets of Langerhans; Male; Middle Aged; Young Adult

2020
Scopoletin increases glucose uptake through activation of PI3K and AMPK signaling pathway and improves insulin sensitivity in 3T3-L1 cells.
    Nutrition research (New York, N.Y.), 2020, Volume: 74

    Topics: 3T3-L1 Cells; Adipocytes; AMP-Activated Protein Kinases; Animals; Deoxyglucose; Enzyme Activation; Glucose Transporter Type 4; Insulin Resistance; Mice; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Scopoletin; Signal Transduction

2020
Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:6

    Topics: Age Factors; Animals; Autophagy; Colchicine; Deoxyglucose; Energy Metabolism; Female; Glucose Tolerance Test; Insulin; Insulin Resistance; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Muscle; Muscle, Skeletal; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Signal Transduction

2020
Cooperative effects of galanin and leptin on alleviation of insulin resistance in adipose tissue of diabetic rats.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:12

    Topics: Adipocytes; Adiponectin; Adipose Tissue; Animals; Body Weight; Deoxyglucose; Diabetes Mellitus, Experimental; Feeding Behavior; Galanin; Glucose Clamp Technique; Glucose Transporter Type 4; Hyperinsulinism; Insulin Resistance; Leptin; Male; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Wistar; RNA, Messenger

2020
Rosemary extract activates AMPK, inhibits mTOR and attenuates the high glucose and high insulin-induced muscle cell insulin resistance.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2021, Volume: 46, Issue:7

    Topics: AMP-Activated Protein Kinases; Animals; Blood Glucose; Cells, Cultured; Deoxyglucose; Disease Models, Animal; Enzyme Activation; Glucose Transporter Type 4; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Muscle Fibers, Skeletal; Phosphorylation; Plant Extracts; Rats; Rosmarinus; Serine; TOR Serine-Threonine Kinases; Tyrosine

2021
Baicalin against obesity and insulin resistance through activation of AKT/AS160/GLUT4 pathway.
    Molecular and cellular endocrinology, 2017, 06-15, Volume: 448

    Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Blood Glucose; Body Weight; Cell Line; Cell Membrane; Deoxyglucose; Feeding Behavior; Flavonoids; Glucose Tolerance Test; Glucose Transporter Type 1; Glucose Transporter Type 4; GTPase-Activating Proteins; Homeostasis; Injections, Intraperitoneal; Insulin Resistance; Male; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Phosphorylation; PPAR gamma; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction

2017
Glucose metabolism and metabolic flexibility in cultured skeletal muscle cells is related to exercise status in young male subjects.
    Archives of physiology and biochemistry, 2018, Volume: 124, Issue:2

    Topics: Adult; Biopsy; Carbon Radioisotopes; Cells, Cultured; Deoxyglucose; Exercise; Fatty Acids, Nonesterified; Gene Expression Regulation; Glucose; Healthy Lifestyle; Humans; Insulin Resistance; Male; Muscle Fibers, Skeletal; Myosin Heavy Chains; Norway; Oleic Acid; Oxygen Consumption; Patient Compliance; Quadriceps Muscle; Sedentary Behavior; Young Adult

2018
The transcriptional response to oxidative stress is part of, but not sufficient for, insulin resistance in adipocytes.
    Scientific reports, 2018, 01-29, Volume: 8, Issue:1

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Cell Line; Deoxyglucose; Diabetes Mellitus, Type 2; Glucose; Insulin; Insulin Resistance; Mice; Oxidative Stress; Signal Transduction; Transcription, Genetic

2018
Effects of exosomes from LPS-activated macrophages on adipocyte gene expression, differentiation, and insulin-dependent glucose uptake.
    Journal of physiology and biochemistry, 2018, Volume: 74, Issue:4

    Topics: Absorption, Physiological; Adipocytes, White; Adipogenesis; Antigens, CD34; Cell Communication; Cells, Cultured; Chemokine CXCL5; Coculture Techniques; Complement C3; Deoxyglucose; Exosomes; Gene Expression Regulation; Humans; Insulin Resistance; Lipopolysaccharides; Macrophage Activation; Macrophages; MicroRNAs; THP-1 Cells; Tumor Necrosis Factor alpha-Induced Protein 3

2018
Immobilization rapidly induces thioredoxin-interacting protein gene expression together with insulin resistance in rat skeletal muscle.
    Journal of applied physiology (Bethesda, Md. : 1985), 2018, 08-01, Volume: 125, Issue:2

    Topics: Animals; Carrier Proteins; Cell Cycle Proteins; Deoxyglucose; Gene Expression; Glucose; Hindlimb; Hindlimb Suspension; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Rats; Rats, Wistar; Signal Transduction; Thioredoxins; Transcription Factors

2018
Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training.
    Scientific reports, 2018, Jul-16, Volume: 8, Issue:1

    Topics: Adenylate Kinase; Animals; Behavior, Animal; Body Weight; Cell Line; Deoxyglucose; Diet, High-Fat; Disease Models, Animal; Female; Glucose Transporter Type 4; Humans; Insulin; Insulin Resistance; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle Proteins; Muscle, Skeletal; Myoblasts; Physical Conditioning, Animal; Proteins; Proteomics; Sedentary Behavior

2018
Role of ABCA1 on membrane cholesterol content, insulin-dependent Akt phosphorylation and glucose uptake in adult skeletal muscle fibers from mice.
    Biochimica et biophysica acta. Molecular and cell biology of lipids, 2018, Volume: 1863, Issue:12

    Topics: 4-Chloro-7-nitrobenzofurazan; Animals; ATP Binding Cassette Transporter 1; Cell Membrane; Cholesterol; Deoxyglucose; Diet, High-Fat; Down-Regulation; Glucose; Glucose Transporter Type 4; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Muscle Fibers, Skeletal; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; Signal Transduction

2018
Nicotine induces insulin resistance via downregulation of Nrf2 in cardiomyocyte.
    Molecular and cellular endocrinology, 2019, 09-15, Volume: 495

    Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Cell Line; Deoxyglucose; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Heme Oxygenase-1; Insulin; Insulin Resistance; Male; Mice, Inbred C57BL; Models, Biological; Myocytes, Cardiac; NF-E2-Related Factor 2; Nicotine; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Reactive Oxygen Species; Receptor, Insulin

2019
Jejunal proteins secreted by db/db mice or insulin-resistant humans impair the insulin signaling and determine insulin resistance.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Adult; Animals; Cell Differentiation; Culture Media, Conditioned; Deoxyglucose; Diabetes Mellitus, Experimental; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Insulin; Insulin Resistance; Jejunum; Mice; Mice, Inbred C57BL; Muscle Fibers, Skeletal; Phosphorylation; Phosphoserine; Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction

2013
Prednisolone induces the Wnt signalling pathway in 3T3-L1 adipocytes.
    Archives of physiology and biochemistry, 2013, Volume: 119, Issue:2

    Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Animals; Deoxyglucose; Gene Expression; Glucocorticoids; Immunity; Insulin; Insulin Resistance; Mice; Prednisolone; Signal Transduction; Tissue Array Analysis; Transcriptome; Wnt Signaling Pathway

2013
Cardamonin ameliorates insulin resistance induced by high insulin and high glucose through the mTOR and signal pathway.
    Planta medica, 2013, Volume: 79, Issue:6

    Topics: Animals; Blood Glucose; Cells, Cultured; Chalcones; Deoxyglucose; Glycogen; Insulin; Insulin Resistance; Mammals; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2013
Blocking central galanin receptors attenuates insulin sensitivity in myocytes of diabetic trained rats.
    Journal of neuroscience research, 2013, Volume: 91, Issue:7

    Topics: Animals; Bradykinin; Cell Membrane; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Exercise Test; Galanin; Glucose Transporter Type 4; Insulin Resistance; Locomotion; Male; Muscle Cells; Peptide Fragments; PPAR alpha; Rats; Rats, Wistar; Receptors, Galanin; RNA, Messenger; Streptozocin; Tritium

2013
Impact of divergent effects of astaxanthin on insulin signaling in L6 cells.
    Endocrinology, 2013, Volume: 154, Issue:8

    Topics: alpha-Tocopherol; Animals; Antioxidants; Blotting, Western; Cell Line; Deoxyglucose; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Myoblasts; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Signal Transduction; Thioctic Acid; Tumor Necrosis Factor-alpha; Xanthophylls

2013
Mitochondrial substrate availability and its role in lipid-induced insulin resistance and proinflammatory signaling in skeletal muscle.
    Diabetes, 2013, Volume: 62, Issue:10

    Topics: Animals; Antimetabolites; Deoxyglucose; Fatty Acids, Nonesterified; Glycolysis; Immunoblotting; Inflammation; Insulin Resistance; Lipid Metabolism; Male; Mitochondria; Muscle, Skeletal; Obesity; Oxidation-Reduction; Oxidative Stress; Palmitates; Rats; Rats, Zucker; Signal Transduction; Up-Regulation

2013
Pinusolide improves high glucose-induced insulin resistance via activation of AMP-activated protein kinase.
    Biochemical and biophysical research communications, 2013, Aug-02, Volume: 437, Issue:3

    Topics: AMP-Activated Protein Kinase Kinases; Animals; Cells, Cultured; Deoxyglucose; Diterpenes; Enzyme Activation; Humans; Hypoglycemic Agents; Insulin Receptor Substrate Proteins; Insulin Resistance; Medicine, Korean Traditional; Muscle Fibers, Skeletal; Phosphorylation; Plant Extracts; Protein Serine-Threonine Kinases; Rats; Signal Transduction; Thuja

2013
Fetuin-A is linked to improved glucose tolerance after short-term exercise training in nonalcoholic fatty liver disease.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, Oct-01, Volume: 115, Issue:7

    Topics: alpha-2-HS-Glycoprotein; Blood Glucose; Body Mass Index; Body Weight; Cells, Cultured; Deoxyglucose; Exercise; Fatty Liver; Female; Glucose Tolerance Test; Glucose Transporter Type 4; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Muscle Cells; Muscle, Skeletal; Non-alcoholic Fatty Liver Disease; Obesity; Triglycerides

2013
Effects of inhibition of serine palmitoyltransferase (SPT) and sphingosine kinase 1 (SphK1) on palmitate induced insulin resistance in L6 myotubes.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Analysis of Variance; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Deoxyglucose; Fatty Acids, Monounsaturated; Insulin Resistance; Muscle Fibers, Skeletal; Palmitates; Phosphotransferases (Alcohol Group Acceptor); Rats; Serine C-Palmitoyltransferase; Thiazoles

2013
Effect of intermittent cold exposure on brown fat activation, obesity, and energy homeostasis in mice.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Adipose Tissue, Brown; Animals; Biomarkers; Body Composition; Body Weight; Cold Temperature; Deoxyglucose; Dioxoles; Energy Metabolism; Feeding Behavior; Glucose; Homeostasis; Hormones; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Obesity; Piperidines; Pyrazoles

2014
Lowered extracellular pH is involved in the pathogenesis of skeletal muscle insulin resistance.
    Biochemical and biophysical research communications, 2014, Feb-28, Volume: 445, Issue:1

    Topics: Animals; Blotting, Western; Cell Differentiation; Cell Line; Cell Membrane; Deoxyglucose; Extracellular Space; Hydrogen-Ion Concentration; Hypoglycemic Agents; Insulin; Insulin Resistance; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Receptor, Insulin

2014
Raising HDL with CETP inhibitor torcetrapib improves glucose homeostasis in dyslipidemic and insulin resistant hamsters.
    Atherosclerosis, 2014, Volume: 233, Issue:2

    Topics: AMP-Activated Protein Kinases; Animals; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins E; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cricetinae; Deoxyglucose; Diet, Atherogenic; Disease Models, Animal; Drug Evaluation, Preclinical; Dyslipidemias; Enzyme Activation; Feces; Glucose; Homeostasis; Hyperglycemia; Insulin Resistance; Male; Mesocricetus; Muscle, Skeletal; Quinolines; Random Allocation; Species Specificity

2014
Dexamethasone-induced insulin resistance: kinetic modeling using novel PET radiopharmaceutical 6-deoxy-6-[(18)F]fluoro-D-glucose.
    Molecular imaging and biology, 2014, Volume: 16, Issue:5

    Topics: Animals; Blood Glucose; Computer Simulation; Deoxyglucose; Dexamethasone; Fluorodeoxyglucose F18; Glucose Clamp Technique; Insulin; Insulin Resistance; Kinetics; Male; Models, Biological; Monte Carlo Method; Positron-Emission Tomography; Radiopharmaceuticals; Rats, Sprague-Dawley

2014
Mechanisms of increased in vivo insulin sensitivity by dietary methionine restriction in mice.
    Diabetes, 2014, Volume: 63, Issue:11

    Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Deoxyglucose; Fibroblast Growth Factors; Hep G2 Cells; Humans; Insulin Resistance; Liver; Methionine; Mice; Phosphorylation; Proto-Oncogene Proteins c-akt

2014
Central alarin ameliorated insulin resistance of adipocytes in type 2 diabetic rats.
    The Journal of endocrinology, 2014, Volume: 223, Issue:3

    Topics: 4-Chloro-7-nitrobenzofurazan; Adipocytes; Adiponectin; Animals; Blood Glucose; Blotting, Western; Body Weight; Cell Membrane; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Galanin-Like Peptide; Gene Expression; Glucose Transporter Type 4; Injections, Intraventricular; Insulin Resistance; Male; Peptide Fragments; Protein Transport; Rats, Wistar; Retinol-Binding Proteins, Plasma; Reverse Transcriptase Polymerase Chain Reaction; Vesicle-Associated Membrane Protein 2

2014
Mechanisms for independent and combined effects of calorie restriction and acute exercise on insulin-stimulated glucose uptake by skeletal muscle of old rats.
    American journal of physiology. Endocrinology and metabolism, 2015, Apr-01, Volume: 308, Issue:7

    Topics: Aging; Animals; Caloric Restriction; Deoxyglucose; Glucose; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Physical Conditioning, Animal; Rats; Rats, Inbred BN; Rats, Inbred F344; Signal Transduction

2015
1,5-anhydroglucitol is associated with early-phase insulin secretion in chinese patients with newly diagnosed type 2 diabetes mellitus.
    Diabetes technology & therapeutics, 2015, Volume: 17, Issue:5

    Topics: Adult; Aged; Asian People; China; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Glycated Serum Albumin; Glycation End Products, Advanced; Homeostasis; Humans; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged; Serum Albumin

2015
Involvement of mTOR in Type 2 CRF Receptor Inhibition of Insulin Signaling in Muscle Cells.
    Molecular endocrinology (Baltimore, Md.), 2015, Volume: 29, Issue:6

    Topics: Adenylyl Cyclases; Animals; Cell Differentiation; Cell Line; Deoxyglucose; Disease Models, Animal; Gene Knockdown Techniques; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice, Obese; Models, Biological; Muscle Cells; Muscle Fibers, Skeletal; Muscle, Skeletal; Phosphorylation; Phosphotyrosine; Physical Conditioning, Animal; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Receptors, Corticotropin-Releasing Hormone; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Urocortins

2015
HOMA-IR Values are Associated With Glycemic Control in Japanese Subjects Without Diabetes or Obesity: The KOBE Study.
    Journal of epidemiology, 2015, Volume: 25, Issue:6

    Topics: Aged; Biomarkers; Blood Glucose; Cross-Sectional Studies; Deoxyglucose; Diabetes Mellitus; Fasting; Female; Glycated Hemoglobin; Homeostasis; Humans; Insulin Resistance; Japan; Male; Middle Aged; Models, Biological; Obesity

2015
Association between Advanced Glycation End Products and Impaired Fasting Glucose: Results from the SALIA Study.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Aged; Biomarkers; Blood Glucose; Chromatography, Liquid; Cross-Sectional Studies; Deoxyglucose; Fasting; Female; Glucose; Glycation End Products, Advanced; Humans; Inflammation; Insulin; Insulin Resistance; Pilot Projects; Prediabetic State; Tandem Mass Spectrometry

2015
Association of hemoglobin A1c and glycated albumin with carotid atherosclerosis in community-dwelling Japanese subjects: the Hisayama Study.
    Cardiovascular diabetology, 2015, Jun-24, Volume: 14

    Topics: Adult; Aged; Atherosclerosis; Biomarkers; Blood Glucose; Blood Pressure; Carotid Artery Diseases; Carotid Intima-Media Thickness; Cohort Studies; Cross-Sectional Studies; Deoxyglucose; Female; Glucose Intolerance; Glucose Tolerance Test; Glycated Hemoglobin; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Independent Living; Insulin Resistance; Japan; Male; Middle Aged; Prospective Studies; Serum Albumin; Statistics as Topic

2015
Effect of a β-Hydroxyphosphonate Analogue of ʟ-Carnitine on Insulin-Sensitive and Insulin-Resistant 3T3-L1 Adipocytes.
    Pharmacology, 2015, Volume: 96, Issue:3-4

    Topics: 3T3-L1 Cells; 4-Chloro-7-nitrobenzofurazan; Adipocytes; Adipogenesis; Animals; Carnitine; Cell Differentiation; Deoxyglucose; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Insulin Resistance; Mice

2015
4-Hydroxyisoleucine ameliorates an insulin resistant-like state in 3T3-L1 adipocytes by regulating TACE/TIMP3 expression.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: 3T3-L1 Cells; ADAM Proteins; ADAM17 Protein; Adipocytes; Animals; Deoxyglucose; Dose-Response Relationship, Drug; Insulin; Insulin Resistance; Isoleucine; Mice; Pioglitazone; Signal Transduction; Thiazolidinediones; Time Factors; Tissue Inhibitor of Metalloproteinase-4; Tissue Inhibitor of Metalloproteinases

2015
Effects of ovariectomy and intrinsic aerobic capacity on tissue-specific insulin sensitivity.
    American journal of physiology. Endocrinology and metabolism, 2016, Feb-01, Volume: 310, Issue:3

    Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Carbon Radioisotopes; Deoxyglucose; Exercise Tolerance; Female; Glucose; Glucose Clamp Technique; Insulin Resistance; Intra-Abdominal Fat; Menopause; Muscle, Skeletal; Ovariectomy; Rats; Subcutaneous Fat; Time Factors; Tritium

2016
Calorie restriction leads to greater Akt2 activity and glucose uptake by insulin-stimulated skeletal muscle from old rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2016, Mar-01, Volume: 310, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Age Factors; Aging; Animals; Caloric Restriction; Crosses, Genetic; Deoxyglucose; Enzyme Activation; Filamins; GTPase-Activating Proteins; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats, Inbred BN; Rats, Inbred F344; Time Factors

2016
3-Deoxyglucosone Induced Acute Glucose Intolerance in Sprague-Dawley Rats: Involvement of Insulin Resistance and Impaired β-cell Function.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2016, Volume: 124, Issue:7

    Topics: Animals; Deoxyglucose; Glucose Intolerance; Insulin Resistance; Insulin-Secreting Cells; Rats; Rats, Sprague-Dawley

2016
4-Hydroxyisoleucine attenuates the inflammation-mediated insulin resistance by the activation of AMPK and suppression of SOCS-3 coimmunoprecipitation with both the IR-β subunit as well as IRS-1.
    Molecular and cellular biochemistry, 2016, Volume: 414, Issue:1-2

    Topics: Adenylate Kinase; Androstadienes; Animals; Cell Line; Deoxyglucose; Enzyme Activation; Glucose Transporter Type 4; Immunoprecipitation; Inflammation; Insulin Receptor Substrate Proteins; Insulin Resistance; Isoleucine; Mice; Muscle Fibers, Skeletal; Phosphorylation; Suppressor of Cytokine Signaling 3 Protein; Tumor Necrosis Factor-alpha; Wortmannin

2016
3-Deoxyglucosone induces insulin resistance by impairing insulin signaling in HepG2 cells.
    Molecular medicine reports, 2016, Volume: 13, Issue:5

    Topics: Animals; Cell Survival; Deoxyglucose; Female; Hep G2 Cells; Humans; Insulin; Insulin Resistance; Male; Mice; Middle Aged; Signal Transduction

2016
Kazinol B from Broussonetia kazinoki improves insulin sensitivity via Akt and AMPK activation in 3T3-L1 adipocytes.
    Fitoterapia, 2016, Volume: 112

    Topics: 3T3-L1 Cells; 4-Chloro-7-nitrobenzofurazan; Adipocytes; Adiponectin; AMP-Activated Protein Kinases; Animals; Broussonetia; Deoxyglucose; Flavonoids; Glucose; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin Resistance; Mice; Phosphorylation; PPAR gamma; Proto-Oncogene Proteins c-akt; Signal Transduction

2016
Activated central galanin type 1 receptor alleviated insulin resistance in diabetic rat muscle.
    Journal of neuroscience research, 2016, Volume: 94, Issue:10

    Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Blood Glucose; Body Weight; Bradykinin; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Galanin; Glucose Tolerance Test; Glucose Transporter Type 4; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Peptide Fragments; PPAR gamma; Rats; Rats, Wistar; Receptor, Galanin, Type 1; Subcellular Fractions; Vesicle-Associated Membrane Protein 2

2016
The GLP-1 receptor agonists exenatide and liraglutide activate Glucose transport by an AMPK-dependent mechanism.
    Journal of translational medicine, 2016, 07-30, Volume: 14, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Biological Transport; Cell Line; Deoxyglucose; Enzyme Activation; Exenatide; Gene Expression Profiling; Gene Silencing; Glucagon-Like Peptide-1 Receptor; Glucose; Humans; Insulin Resistance; Liraglutide; Mice; Muscle Fibers, Skeletal; Papio; Peptides; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyruvaldehyde; Rats; Signal Transduction; Time Factors; Venoms

2016
A Direct Comparison of Metabolic Responses to High-Fat Diet in C57BL/6J and C57BL/6NJ Mice.
    Diabetes, 2016, Volume: 65, Issue:11

    Topics: Animals; Deoxyglucose; Diet, High-Fat; Disease Susceptibility; Hydrogen Peroxide; Insulin Resistance; Metabolic Diseases; Mice, Inbred C57BL; Mitochondria

2016
Conditioned Media From Adipose Tissue Derived Mesenchymal Stem Cells Reverse Insulin Resistance in Cellular Models.
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:8

    Topics: 3T3-L1 Cells; 4-Chloro-7-nitrobenzofurazan; Adipocytes; Adipose Tissue; Animals; Biological Transport; Cell Differentiation; Cells, Cultured; Culture Media, Conditioned; Deoxyglucose; Gene Expression Regulation; Glucose Transporter Type 4; Insulin; Insulin Resistance; Interleukin-6; Mesenchymal Stem Cells; Mice; Myoblasts; Proto-Oncogene Proteins c-akt; Serpin E2; Signal Transduction; Triglycerides

2017
Metformin ameliorates high uric acid-induced insulin resistance in skeletal muscle cells.
    Molecular and cellular endocrinology, 2017, 03-05, Volume: 443

    Topics: 4-Chloro-7-nitrobenzofurazan; Acetylcysteine; Adenylate Kinase; Animals; Antioxidants; Cell Line; Deoxyglucose; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Metformin; Mice; Models, Biological; Muscle Cells; Muscle, Skeletal; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Uric Acid

2017
Palmitate-Induced Vacuolar-Type H
    Diabetes, 2017, Volume: 66, Issue:6

    Topics: Animals; Blotting, Western; Carbon Radioisotopes; CD36 Antigens; Cells, Cultured; Deoxyglucose; Diet, High-Fat; Endosomes; Glucose; Heart; Humans; Hydrogen-Ion Concentration; Induced Pluripotent Stem Cells; Insulin Resistance; Male; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Myosin Heavy Chains; Palmitates; Rats; Rats, Inbred Lew; RNA, Messenger; Triglycerides; Tritium; Troponin T; Vacuolar Proton-Translocating ATPases

2017
Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase expression ameliorates diet-induced obesity and insulin resistance in mice.
    Journal of molecular endocrinology, 2008, Volume: 41, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Blood Glucose; Body Weight; Carbenoxolone; Carbohydrate Dehydrogenases; Cells, Cultured; Corticosterone; Deoxyglucose; Dietary Fats; Gene Expression; Glucose Tolerance Test; Hepatocytes; Homeostasis; Immunoblotting; Insulin; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Receptors, Glucocorticoid; RNA, Messenger

2008
1,25-Dihydroxyvitamin D improved the free fatty-acid-induced insulin resistance in cultured C2C12 cells.
    Diabetes/metabolism research and reviews, 2008, Volume: 24, Issue:6

    Topics: Animals; Biological Transport; Calcitriol; Cell Line; Deoxyglucose; Fatty Acids, Nonesterified; Glucose; Humans; Insulin Resistance; Mice; Muscle Fibers, Skeletal; Myoblasts

2008
Crosstalk between the AMP-activated kinase and insulin signaling pathways rescues murine blastocyst cells from insulin resistance.
    Reproduction (Cambridge, England), 2008, Volume: 136, Issue:3

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Apoptosis; Blastocyst; Blotting, Western; Cell Line; Deoxyglucose; Enzyme Activation; Female; Hypoglycemic Agents; Insulin; Insulin Resistance; Mice; Phenformin; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Ribonucleosides; Ribosomal Protein S6 Kinases, 70-kDa; RNA Interference; Signal Transduction

2008
Endothelial and vascular dysfunctions and insulin resistance in rats fed a high-fat, high-sucrose diet.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:3

    Topics: Animals; Blood Pressure; Blotting, Western; Body Weight; Deoxyglucose; Diet; Dietary Fats; Endothelin-1; Endothelium, Vascular; Fatty Acids, Nonesterified; Fluorescent Antibody Technique; Glucose Clamp Technique; Heart Rate; Insulin; Insulin Resistance; Male; Obesity; Organ Size; Rats; Rats, Sprague-Dawley; Sucrose; Triglycerides; Tyrosine; Vascular Diseases; Vascular Resistance

2008
Age-related differences in skeletal muscle insulin signaling: the role of stress kinases and heat shock proteins.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 105, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Age Factors; Aging; Animals; Deoxyglucose; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heat-Shock Proteins; Homeostasis; HSP27 Heat-Shock Proteins; HSP72 Heat-Shock Proteins; I-kappa B Kinase; I-kappa B Proteins; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Male; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Neoplasm Proteins; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred F344; Signal Transduction

2008
Chromium (D-phenylalanine)3 supplementation alters glucose disposal, insulin signaling, and glucose transporter-4 membrane translocation in insulin-resistant mice.
    The Journal of nutrition, 2008, Volume: 138, Issue:10

    Topics: Animal Feed; Animals; Biological Transport; Blood Glucose; Deoxyglucose; Dietary Supplements; Glucose Tolerance Test; Glucose Transporter Type 4; Insulin; Insulin Resistance; Mice; Muscle Proteins; Muscle, Skeletal; Organometallic Compounds; Phenylalanine; Protein Transport; Signal Transduction

2008
Cecropia obtusifolia Bertol and its active compound, chlorogenic acid, stimulate 2-NBDglucose uptake in both insulin-sensitive and insulin-resistant 3T3 adipocytes.
    Journal of ethnopharmacology, 2008, Dec-08, Volume: 120, Issue:3

    Topics: 4-Chloro-7-nitrobenzofurazan; Adipocytes; Adipogenesis; Analysis of Variance; Animals; Cecropia Plant; Cell Line; Chlorogenic Acid; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Insulin; Insulin Resistance; Mexico; Mice; Phytotherapy; Plant Extracts; Plant Structures

2008
Fatty acid-induced NF-kappaB activation and insulin resistance in skeletal muscle are chain length dependent.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 296, Issue:1

    Topics: Animals; Cell Line; Deoxyglucose; Electrophoretic Mobility Shift Assay; Fatty Acids; Glucose Transporter Type 4; Insulin Resistance; Mice; Muscle, Skeletal; NF-kappa B; Palmitic Acid; Rats; Structure-Activity Relationship; Transcription, Genetic

2009
Corticosterone suppresses insulin- and NO-stimulated muscle glucose uptake in broiler chickens (Gallus gallus domesticus).
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2009, Volume: 149, Issue:3

    Topics: Animals; Biological Transport; Blood Glucose; Chickens; Corticosterone; Deoxyglucose; Diet; Enzyme Inhibitors; Glycogen; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Resistance; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Time Factors

2009
Impact of lipid phosphatases SHIP2 and PTEN on the time- and Akt-isoform-specific amelioration of TNF-alpha-induced insulin resistance in 3T3-L1 adipocytes.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 296, Issue:1

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Deoxyglucose; Glycogen Synthase Kinase 3; GTPase-Activating Proteins; Inositol Polyphosphate 5-Phosphatases; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Transfection; Tumor Necrosis Factor-alpha

2009
Knockdown of JNK rescues 3T3-L1 adipocytes from insulin resistance induced by mitochondrial dysfunction.
    Biochemical and biophysical research communications, 2009, Jan-23, Volume: 378, Issue:4

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Deoxyglucose; Gene Knockdown Techniques; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Mitochondrial Diseases; Mitogen-Activated Protein Kinase 8; Phosphatidylinositol 3-Kinases; Phosphorylation; Serine; Tyrosine

2009
Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat diet.
    Diabetes, 2009, Volume: 58, Issue:3

    Topics: Animals; Blood Glucose; Deoxyglucose; Dietary Fats; Glucose Tolerance Test; Hot Temperature; HSP72 Heat-Shock Proteins; I-kappa B Kinase; Insulin Resistance; Male; Mannitol; Muscle, Skeletal; Rats; Rats, Wistar

2009
Effect of acute high-intensity intermittent swimming on post-exercise insulin responsiveness in epitrochlearis muscle of fed rats.
    Metabolism: clinical and experimental, 2009, Volume: 58, Issue:2

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Blood Glucose; Deoxyglucose; Eating; Glucose Transporter Type 4; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Phosphorylation; Physical Exertion; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Swimming

2009
Is "fat-induced" muscle insulin resistance rapidly reversible?
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 297, Issue:1

    Topics: Animals; Biological Transport; Blood Glucose; Deoxyglucose; Diet; Dietary Fats; Fasting; Fatty Acids, Nonesterified; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Rats; Rats, Wistar; Time Factors

2009
[Relationship between expressions of serum amyloid A and insulin resistance in 3T3-L1 adipocytes].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2009, Volume: 29, Issue:5

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Deoxyglucose; Dexamethasone; Enzyme-Linked Immunosorbent Assay; Insulin Resistance; Mice; RNA, Messenger; Serum Amyloid A Protein

2009
PTEN and SHIP2 regulates PI3K/Akt pathway through focal adhesion kinase.
    Molecular and cellular endocrinology, 2009, Oct-15, Volume: 309, Issue:1-2

    Topics: Animals; Cell Differentiation; Cell Line; Deoxyglucose; Down-Regulation; Enzyme Inhibitors; Focal Adhesion Protein-Tyrosine Kinases; Inositol Polyphosphate 5-Phosphatases; Insulin; Insulin Resistance; Mice; Muscle, Skeletal; Mutation; Phosphatidylinositol 3-Kinases; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; RNA, Small Interfering

2009
Screening for type 2 diabetes in obese youth.
    Pediatrics, 2009, Volume: 124, Issue:2

    Topics: Adolescent; Age Factors; Blood Glucose; Body Mass Index; Child; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Hyperglycemia; Insulin; Insulin Resistance; Male; Mass Screening; Obesity; Predictive Value of Tests; ROC Curve; Texas

2009
Oleate protects against palmitate-induced insulin resistance in L6 myotubes.
    The British journal of nutrition, 2009, Volume: 102, Issue:11

    Topics: Androstadienes; Animals; Cell Membrane; Cell Survival; Cells, Cultured; Chromones; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme Inhibitors; Insulin Resistance; Morpholines; Muscle Fibers, Skeletal; Myoblasts, Skeletal; Oleic Acid; Palmitates; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Wortmannin

2009
Muscle contraction, but not insulin, increases microvascular blood volume in the presence of free fatty acid-induced insulin resistance.
    Diabetes, 2009, Volume: 58, Issue:11

    Topics: AMP-Activated Protein Kinases; Animals; Blood Volume; Deoxyglucose; Electric Stimulation; Fatty Acids, Nonesterified; Hindlimb; Hyperinsulinism; Insulin; Insulin Resistance; Iodine Radioisotopes; Kinetics; Male; Microcirculation; Muscle, Skeletal; Phosphorylation; Rats; Rats, Sprague-Dawley

2009
11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle.
    Diabetes, 2009, Volume: 58, Issue:11

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Cell Line; Cells, Cultured; Deoxyglucose; Dexamethasone; Glucocorticoids; Humans; Insulin; Insulin Resistance; Kinetics; Mice; Muscle, Skeletal; Myoblasts; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger

2009
Reduced AMP-activated protein kinase activity in mouse skeletal muscle does not exacerbate the development of insulin resistance with obesity.
    Diabetologia, 2009, Volume: 52, Issue:11

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinase Kinases; Animals; Body Weight; Deoxyglucose; Dietary Fats; Insulin Resistance; Kinetics; Lipid Peroxidation; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Skeletal; Obesity; Protein Kinases; Reference Values; Ribonucleotides

2009
Melatonin improves glucose homeostasis and endothelial vascular function in high-fat diet-fed insulin-resistant mice.
    Endocrinology, 2009, Volume: 150, Issue:12

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Deoxyglucose; Dietary Fats; Endothelium, Vascular; Glucose; Glucose Tolerance Test; Heart Rate; Homeostasis; In Vitro Techniques; Insulin; Insulin Resistance; Male; Melatonin; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt

2009
Insulin resistance due to lipid-induced signaling defects could be prevented by mahanine.
    Molecular and cellular biochemistry, 2010, Volume: 336, Issue:1-2

    Topics: Animals; Blood Glucose; Carbazoles; Cricetinae; Deoxyglucose; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Mesocricetus; Murraya; Muscle Fibers, Skeletal; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphorylation; Plant Leaves; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Rats; Receptor, Insulin; Signal Transduction

2010
Apelin is necessary for the maintenance of insulin sensitivity.
    American journal of physiology. Endocrinology and metabolism, 2010, Volume: 298, Issue:1

    Topics: Adipokines; AMP-Activated Protein Kinases; Animals; Apelin; Carrier Proteins; Cells, Cultured; Chromones; Deoxyglucose; Diabetes Mellitus, Type 2; Dietary Sucrose; Enzyme Inhibitors; Hyperinsulinism; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Muscle, Skeletal; Myoblasts; NG-Nitroarginine Methyl Ester; Obesity; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Leptin; Signal Transduction; Tritium

2010
Gestational and postnatal low protein diet alters insulin sensitivity in female rats.
    Experimental biology and medicine (Maywood, N.J.), 2009, Volume: 234, Issue:12

    Topics: Aging; Animals; Deoxyglucose; Dietary Proteins; Female; Gestational Age; Glucose Tolerance Test; Glycerol; Glycogen; Insulin Resistance; Lactation; Liver; Male; Muscle, Skeletal; Pregnancy; Pregnancy Complications; Protein Deficiency; Rats; Rats, Wistar

2009
3beta-taraxerol of Mangifera indica, a PI3K dependent dual activator of glucose transport and glycogen synthesis in 3T3-L1 adipocytes.
    Biochimica et biophysica acta, 2010, Volume: 1800, Issue:3

    Topics: 3T3 Cells; Adipocytes; Animals; Blood Glucose; Cell Survival; Deoxyglucose; Diabetes Mellitus, Type 2; Enzyme Activation; Glucose; Glycogen; Humans; Insulin Resistance; Mangifera; Mice; Oleanolic Acid; Phosphatidylinositol 3-Kinases; Plant Extracts

2010
The characterization of Abelson helper integration site-1 in skeletal muscle and its links to the metabolic syndrome.
    Metabolism: clinical and experimental, 2010, Volume: 59, Issue:7

    Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Blood Glucose; Blotting, Western; Body Weight; Cells, Cultured; Cohort Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Genotype; Glucose; Humans; Insulin; Insulin Resistance; Metabolic Syndrome; Mexican Americans; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts; Obesity; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection

2010
Progesterone inhibits glucose uptake by affecting diverse steps of insulin signaling in 3T3-L1 adipocytes.
    American journal of physiology. Endocrinology and metabolism, 2010, Volume: 298, Issue:4

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Antimetabolites; Blotting, Western; Cell Differentiation; Cell Membrane; Deoxyglucose; Female; Glucose; Glucose Transporter Type 4; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Microscopy, Confocal; Oncogene Protein v-akt; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pregnancy; Progesterone; Protein Transport; rho GTP-Binding Proteins; Signal Transduction

2010
Significant improvement of insulin resistance of GK rats by treatment with sodium selenate.
    Biological trace element research, 2010, Volume: 138, Issue:1-3

    Topics: Adipocytes; Animals; Biological Transport; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose Clamp Technique; Insulin; Insulin Resistance; Male; Rats; Rats, Wistar; Selenic Acid; Selenium Compounds

2010
Curcumin improves insulin resistance in skeletal muscle of rats.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2011, Volume: 21, Issue:7

    Topics: AMP-Activated Protein Kinase Kinases; Animals; Biological Transport; Cell Line; Curcumin; Deoxyglucose; Diabetes Mellitus, Experimental; Dietary Fats; Dietary Supplements; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Male; Muscle, Skeletal; Palmitic Acid; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Random Allocation; Rats; Rats, Wistar; Signal Transduction

2011
Acute oxidative stress can reverse insulin resistance by inactivation of cytoplasmic JNK.
    The Journal of biological chemistry, 2010, Jul-09, Volume: 285, Issue:28

    Topics: Animals; Cytoplasm; Deoxyglucose; Diabetes Mellitus, Type 2; Dual-Specificity Phosphatases; Enzyme Activation; Gene Expression Regulation, Enzymologic; Insulin; Insulin Resistance; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Phosphatases; Models, Biological; Muscles; Oxidative Stress; Signal Transduction

2010
G protein-coupled receptor kinase 2 plays a relevant role in insulin resistance and obesity.
    Diabetes, 2010, Volume: 59, Issue:10

    Topics: Adipocytes; Adipose Tissue; Animals; Biological Transport; Cell Line, Tumor; Deoxyglucose; Epididymis; G-Protein-Coupled Receptor Kinase 2; Gene Silencing; Glucose; Humans; Insulin; Insulin Resistance; Liposarcoma; Male; Mice; Myoblasts; Obesity; Signal Transduction

2010
Increases in energy intake, insulin resistance and stress in rats before Wenchuan earthquake far from the epicenter.
    Experimental biology and medicine (Maywood, N.J.), 2010, Volume: 235, Issue:10

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Animals; Base Sequence; China; Corticosterone; Deoxyglucose; DNA Primers; Earthquakes; Energy Intake; Glucose Clamp Technique; Insulin Resistance; Male; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Stress, Physiological; Time Factors

2010
Inhibition of O-GlcNAcase using a potent and cell-permeable inhibitor does not induce insulin resistance in 3T3-L1 adipocytes.
    Chemistry & biology, 2010, Sep-24, Volume: 17, Issue:9

    Topics: 3T3-L1 Cells; Acetylglucosamine; Adipocytes; Animals; beta-N-Acetylhexosaminidases; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Deoxyglucose; Enzyme Inhibitors; Humans; Indolizines; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Oximes; Phenylcarbamates; Phosphorylation; Proto-Oncogene Proteins c-akt

2010
Overactivation of NF-κB impairs insulin sensitivity and mediates palmitate-induced insulin resistance in C2C12 skeletal muscle cells.
    Endocrine, 2010, Volume: 37, Issue:1

    Topics: Animals; Cell Line; Deoxyglucose; Gene Expression Regulation; Gene Silencing; Glucose Transporter Type 4; I-kappa B Proteins; Inflammation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Muscle Fibers, Skeletal; Myoblasts, Skeletal; NF-kappa B; NF-KappaB Inhibitor alpha; Palmitic Acid; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; RNA, Small Interfering

2010
Ghrelin inhibits insulin resistance induced by glucotoxicity and lipotoxicity in cardiomyocyte.
    Peptides, 2011, Volume: 32, Issue:2

    Topics: AMP-Activated Protein Kinases; Animals; Cell Shape; Cells, Cultured; Chromones; Deoxyglucose; Enzyme Inhibitors; Gene Expression; Ghrelin; Glucose; Glucose Transporter Type 4; Insulin Resistance; Male; Morpholines; Myocytes, Cardiac; Palmitic Acid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; PPAR gamma; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction

2011
Both type I and II IFN induce insulin resistance by inducing different isoforms of SOCS expression in 3T3-L1 adipocytes.
    American journal of physiology. Endocrinology and metabolism, 2011, Volume: 300, Issue:6

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Azo Compounds; Blotting, Western; Coloring Agents; Deoxyglucose; Humans; Immunoprecipitation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Interferon Type I; Interferon-beta; Interferon-gamma; Mice; Phosphorylation; Recombinant Proteins; Signal Transduction; STAT Transcription Factors; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins

2011
Inhibitory effects of dioscorea polysaccharide on TNF-α-induced insulin resistance in mouse FL83B cells.
    Journal of agricultural and food chemistry, 2011, May-25, Volume: 59, Issue:10

    Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Cell Line; Deoxyglucose; Dioscorea; Glucose Transporter Type 2; Insulin Resistance; Liver; Mice; Polysaccharides; Tumor Necrosis Factor-alpha

2011
Pioglitazone upregulates adiponectin receptor 2 in 3T3-L1 adipocytes.
    Life sciences, 2011, Jun-06, Volume: 88, Issue:23-24

    Topics: 3T3-L1 Cells; Adipocytes; AMP-Activated Protein Kinases; Animals; Deoxyglucose; Hypoglycemic Agents; Insulin; Insulin Resistance; Mice; Phosphorylation; Pioglitazone; PPAR gamma; Receptors, Adiponectin; RNA, Messenger; Thiazolidinediones; Up-Regulation

2011
The Monascus metabolite monascin against TNF-α-induced insulin resistance via suppressing PPAR-γ phosphorylation in C2C12 myotubes.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011, Volume: 49, Issue:10

    Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Blotting, Western; Cell Line; Deoxyglucose; Heterocyclic Compounds, 3-Ring; Insulin Resistance; Mice; Monascus; Muscle Fibers, Skeletal; Phosphatidylinositol 3-Kinases; Phosphorylation; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha

2011
Serum amyloid A is a growth factor for 3T3-L1 adipocytes, inhibits differentiation and promotes insulin resistance.
    International journal of obesity (2005), 2012, Volume: 36, Issue:8

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Cell Differentiation; Cell Proliferation; Deoxyglucose; Flow Cytometry; Humans; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Mice; Mice, Obese; Real-Time Polymerase Chain Reaction; RNA, Messenger; Serum Amyloid A Protein; Up-Regulation

2012
A novel method to measure glucose uptake and myosin heavy chain isoform expression of single fibers from rat skeletal muscle.
    Diabetes, 2012, Volume: 61, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Aminoimidazole Carboxamide; Animals; Deoxyglucose; Gene Expression Regulation; Genotype; Glucose; I-kappa B Kinase; Insulin; Insulin Resistance; Male; Muscle Fibers, Skeletal; Myosin Heavy Chains; Nerve Tissue Proteins; Protein Isoforms; Rats; Rats, Wistar; Rats, Zucker; Ribonucleotides

2012
Fibroblast growth factor-21 protects human skeletal muscle myotubes from palmitate-induced insulin resistance by inhibiting stress kinase and NF-κB.
    Metabolism: clinical and experimental, 2012, Volume: 61, Issue:8

    Topics: 4-Chloro-7-nitrobenzofurazan; Blotting, Western; Deoxyglucose; Enzyme Activation; Fibroblast Growth Factors; Glucose Transporter Type 1; Glucose Transporter Type 4; Humans; I-kappa B Kinase; Insulin; Insulin Resistance; MAP Kinase Kinase 4; Muscle Fibers, Skeletal; NF-kappa B p50 Subunit; Palmitic Acid; Phosphorylation; Polymerase Chain Reaction; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Signal Transduction

2012
Ameliorative effects of polyunsaturated fatty acids against palmitic acid-induced insulin resistance in L6 skeletal muscle cells.
    Lipids in health and disease, 2012, Mar-12, Volume: 11

    Topics: Animals; Cell Line; Cell Survival; Deoxyglucose; Down-Regulation; Fatty Acids, Unsaturated; Glucose Transporter Type 4; High-Throughput Screening Assays; Hypoglycemic Agents; Insulin Resistance; Muscle Fibers, Skeletal; Palmitic Acid; Rats; Receptor, Insulin

2012
Adipocyte expression of PU.1 transcription factor causes insulin resistance through upregulation of inflammatory cytokine gene expression and ROS production.
    American journal of physiology. Endocrinology and metabolism, 2012, Jun-15, Volume: 302, Issue:12

    Topics: 3T3 Cells; Adipocytes; Animals; Blotting, Western; Cell Differentiation; Cytokines; Deoxyglucose; Gene Silencing; Insulin; Insulin Resistance; Interferon Regulatory Factors; Lipolysis; Mice; Mice, Inbred C57BL; NADPH Oxidases; Obesity; Plasmids; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; Up-Regulation

2012
Carbohydrate- and lipid-enriched meals acutely disrupt glycemic homeostasis by inducing transient insulin resistance in rats.
    Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:5

    Topics: Animals; Blood Glucose; Deoxyglucose; Diet, High-Fat; Dietary Carbohydrates; Dietary Fats; DNA-Binding Proteins; Fasting; Fatty Acids, Nonesterified; Glucose Tolerance Test; Glycemic Index; Glycogen; Glycogen Synthase Kinase 3; Homeostasis; Insulin; Insulin Resistance; Liver; Male; Muscle, Skeletal; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Transcription Factors

2012
Effect of water extracts from edible Myrtaceae plants on uptake of 2-(n-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose in TNF-α-treated FL83B mouse hepatocytes.
    Phytotherapy research : PTR, 2013, Volume: 27, Issue:2

    Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Cell Line; Deoxyglucose; Fruit; Glucose; Hepatocytes; Hydrolyzable Tannins; Hypoglycemic Agents; Insulin Resistance; Mice; Myrtaceae; Plant Extracts; Plant Leaves; Plants, Edible; Tumor Necrosis Factor-alpha

2013
Intracerebroventricular administration of galanin antagonist sustains insulin resistance in adipocytes of type 2 diabetic trained rats.
    Molecular and cellular endocrinology, 2012, Sep-25, Volume: 361, Issue:1-2

    Topics: Adipocytes; Animals; Blood Glucose; Body Weight; Bradykinin; Cell Membrane; Cholesterol; Deoxyglucose; Diabetes Mellitus, Type 2; Fasting; Galanin; Gene Expression Regulation; Glucose Clamp Technique; Glucose Transporter Type 4; Hypothalamus; Injections, Intraventricular; Insulin; Insulin Resistance; Male; Peptide Fragments; Physical Conditioning, Animal; Rats; Rats, Wistar; RNA, Messenger; Triglycerides

2012
PTEN, a widely known negative regulator of insulin/PI3K signaling, positively regulates neuronal insulin resistance.
    Molecular biology of the cell, 2012, Volume: 23, Issue:19

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Butadienes; Cell Line, Tumor; Deoxyglucose; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Kinase 1; Gene Knockdown Techniques; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Inositol Polyphosphate 5-Phosphatases; Insulin; Insulin Resistance; MAP Kinase Signaling System; Mice; Neurons; Nitriles; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphoric Monoester Hydrolases; Phosphorylation; Primary Cell Culture; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; RNA Interference

2012
Leukocyte antigen-related inhibition attenuates palmitate-induced insulin resistance in muscle cells.
    The Journal of endocrinology, 2012, Volume: 215, Issue:1

    Topics: Animals; Cells, Cultured; Deoxyglucose; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Knockdown Techniques; Insulin Resistance; Mice; Muscle Cells; Muscle Fibers, Skeletal; Oncogene Protein v-akt; Palmitic Acid; Receptor-Like Protein Tyrosine Phosphatases, Class 2; RNA, Messenger; Up-Regulation

2012
Isoorientin reverts TNF-α-induced insulin resistance in adipocytes activating the insulin signaling pathway.
    Endocrinology, 2012, Volume: 153, Issue:11

    Topics: 4-Chloro-7-nitrobenzofurazan; Adipocytes; Animals; Cell Line; Deoxyglucose; Glucose Transporter Type 4; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Luteolin; Mice; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Signal Transduction; Tumor Necrosis Factor-alpha

2012
MiRNA-21 reverses high glucose and high insulin induced insulin resistance in 3T3-L1 adipocytes through targeting phosphatase and tensin homologue.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2012, Volume: 120, Issue:9

    Topics: 3T3-L1 Cells; Adipocytes, White; Animals; Biological Transport; Deoxyglucose; Down-Regulation; Glucose Transporter Type 4; Hyperglycemia; Hyperinsulinism; Insulin Resistance; Mice; MicroRNAs; Protein Transport; PTEN Phosphohydrolase; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction

2012
Sutherlandia frutescens prevents changes in diabetes-related gene expression in a fructose-induced insulin resistant cell model.
    Journal of ethnopharmacology, 2013, Mar-27, Volume: 146, Issue:2

    Topics: Cell Line; Deoxyglucose; Diabetes Mellitus, Type 2; Fabaceae; Fructose; Gene Expression Profiling; Glucose Oxidase; Hepatocytes; Humans; Hypoglycemic Agents; Insulin Resistance; Plant Extracts

2013
Neutralization of tumor necrosis factor reverses age-induced impairment of insulin responsiveness in skeletal muscle of Sprague-Dawley rats.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:8

    Topics: Aging; Animals; Body Composition; Deoxyglucose; Insulin Resistance; Male; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

2002
ACE inhibitor improves insulin resistance in diabetic mouse via bradykinin and NO.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Transport; Blood Glucose; Bradykinin; Cell Line; Deoxyglucose; Diabetes Mellitus, Type 2; Glucose Transporter Type 4; Insulin Receptor Substrate Proteins; Insulin Resistance; Kinetics; Male; Mice; Mice, Inbred C57BL; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Nitric Oxide; Phosphoproteins; Phosphorylation; Protein Transport; Thiazepines

2002
Metformin enhances insulin signalling in insulin-dependent and-independent pathways in insulin resistant muscle cells.
    British journal of pharmacology, 2002, Volume: 137, Issue:3

    Topics: Animals; Cells, Cultured; Deoxyglucose; Hypoglycemic Agents; Imidazoles; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Metformin; Mice; Mitogen-Activated Protein Kinases; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Pyridines; Receptor, Insulin; Signal Transduction; Tyrosine

2002
Insulin stimulates long-chain fatty acid utilization by rat cardiac myocytes through cellular redistribution of FAT/CD36.
    Diabetes, 2002, Volume: 51, Issue:10

    Topics: Androstadienes; Animals; Biological Transport; CD36 Antigens; Deoxyglucose; Diabetes Mellitus, Type 2; Electric Stimulation; Enzyme Inhibitors; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Membrane Glycoproteins; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Organic Anion Transporters; Palmitates; Phloretin; Rats; Rats, Inbred Lew; Succinimides; Transport Vesicles; Wortmannin

2002
Gliclazide increases insulin receptor tyrosine phosphorylation but not p38 phosphorylation in insulin-resistant skeletal muscle cells.
    The Journal of experimental biology, 2002, Volume: 205, Issue:Pt 23

    Topics: Animals; Cell Line; Deoxyglucose; Enzyme Inhibitors; Gliclazide; Hypoglycemic Agents; Imidazoles; Insulin; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Pyridines; Receptor, Insulin; Signal Transduction; Tyrosine

2002
A steroidal glycoside from Polygonatum odoratum (Mill.) Druce. improves insulin resistance but does not alter insulin secretion in 90% pancreatectomized rats.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:10

    Topics: Animals; Antimetabolites; Blood Glucose; Body Weight; Deoxyglucose; Eating; Glucose; Glucose Clamp Technique; Glycogen Synthase; Glycosides; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver Glycogen; Male; Muscle, Skeletal; Pancreatectomy; Plant Extracts; Polygonatum; Rats; Rats, Sprague-Dawley; Steroids

2002
Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Dec-10, Volume: 99, Issue:25

    Topics: Acetyl-CoA Carboxylase; Adiponectin; AMP-Activated Protein Kinases; Animals; Biological Transport; Deoxyglucose; Enzyme Activation; Fatty Acids; Female; Glucose; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Multienzyme Complexes; Muscle Proteins; Muscle, Skeletal; Oxidation-Reduction; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proteins; Rats; Rats, Sprague-Dawley; Signal Transduction

2002
Agent and cell-type specificity in the induction of insulin resistance by HIV protease inhibitors.
    AIDS (London, England), 2003, Jan-03, Volume: 17, Issue:1

    Topics: Adipocytes; Cell Line; Deoxyglucose; Drug Administration Schedule; Fibroblasts; Glucose Transporter Type 1; HIV Protease Inhibitors; Humans; Indinavir; Insulin Resistance; Lipolysis; Monosaccharide Transport Proteins; Muscle, Skeletal; Nelfinavir; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Saquinavir

2003
Development of insulin resistance and reversal by thiazolidinediones in C2C12 skeletal muscle cells.
    Biochemical pharmacology, 2003, Jan-15, Volume: 65, Issue:2

    Topics: Animals; Biological Transport; Cell Differentiation; Cells, Cultured; Culture Media, Serum-Free; Deoxyglucose; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Muscle, Skeletal; Myoblasts; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Pioglitazone; Receptor, Insulin; Rosiglitazone; Thiazoles; Thiazolidinediones; Tyrosine

2003
Programming of rat muscle and fat metabolism by in utero overexposure to glucocorticoids.
    Endocrinology, 2003, Volume: 144, Issue:3

    Topics: Adipose Tissue; Animals; Birth Weight; Blood Glucose; Body Weight; Deoxyglucose; Dexamethasone; Epididymis; Fatty Acids; Female; Glucocorticoids; Glucose Transporter Type 4; Glycogen; Hyperglycemia; Insulin Resistance; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Receptors, Glucocorticoid; RNA, Messenger; Transcription Factors

2003
Interleukin-6 gene expression is increased in insulin-resistant rat skeletal muscle following insulin stimulation.
    Biochemical and biophysical research communications, 2003, Mar-21, Volume: 302, Issue:4

    Topics: Animals; Animals, Genetically Modified; Blood Glucose; Deoxyglucose; Humans; Insulin; Insulin Resistance; Interleukin-6; MAP Kinase Signaling System; Muscle Contraction; Muscle, Skeletal; Protein Serine-Threonine Kinases; Rats; RNA, Messenger

2003
Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance.
    Diabetes, 2003, Volume: 52, Issue:4

    Topics: Adult; Body Mass Index; Deoxyglucose; Enzyme Activation; Epidermal Growth Factor; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Muscle, Skeletal; Obesity; Oncogene Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction

2003
Deficiency of adrenomedullin induces insulin resistance by increasing oxidative stress.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:5

    Topics: Adrenomedullin; Aging; Animals; Antioxidants; Blood Pressure; Body Weight; Cyclic N-Oxides; Deoxyglucose; Female; Genotype; In Vitro Techniques; Insulin; Insulin Resistance; Isoprostanes; Male; Mice; Mice, Knockout; Muscle, Skeletal; Oxidative Stress; Peptides

2003
Ethanol feeding induces insulin resistance with enhanced PI 3-kinase activation.
    Biochemical and biophysical research communications, 2003, Apr-11, Volume: 303, Issue:3

    Topics: Adipose Tissue; Alcohol Drinking; Animals; Deoxyglucose; Enzyme Activation; Ethanol; Glucose Clamp Technique; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Liver; Male; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Signal Transduction; Tyrosine

2003
Peripheral insulin resistance develops in transgenic rats overexpressing phosphoenolpyruvate carboxykinase in the kidney.
    Diabetologia, 2003, Volume: 46, Issue:10

    Topics: Animals; Animals, Genetically Modified; Deoxyglucose; Glucose; Glucose Transporter Type 4; Glycogen; Insulin Resistance; Kidney; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Phosphoenolpyruvate Carboxykinase (GTP); Rats; RNA, Messenger; Triglycerides

2003
Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones.
    The Journal of clinical investigation, 2003, Volume: 112, Issue:4

    Topics: Adipose Tissue; Alleles; Animals; Deoxyglucose; Fatty Acids; Genotype; Glucose; Glucose Tolerance Test; Insulin; Insulin Resistance; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Mice, Transgenic; Models, Genetic; Muscle, Skeletal; Muscles; Oligonucleotide Array Sequence Analysis; Receptors, Cytoplasmic and Nuclear; Recombination, Genetic; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Triglycerides

2003
Skeletal muscle cells from insulin-resistant (non-diabetic) individuals are susceptible to insulin desensitization by palmitate.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2003, Volume: 35, Issue:10

    Topics: Adult; Cells, Cultured; Deoxyglucose; Female; Glycogen; Glycogen Synthase Kinase 3; Humans; Insulin; Insulin Resistance; Male; Muscle Fibers, Skeletal; Muscle, Skeletal; Palmitic Acid; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt

2003
Effects of stevioside on glucose transport activity in insulin-sensitive and insulin-resistant rat skeletal muscle.
    Metabolism: clinical and experimental, 2004, Volume: 53, Issue:1

    Topics: Animals; Biological Transport; Blood Glucose; Deoxyglucose; Diterpenes; Diterpenes, Kaurane; Fatty Acids, Nonesterified; Female; Glucose; Glucose Tolerance Test; Glucosides; Hypoglycemic Agents; Insulin; Insulin Resistance; Muscle, Skeletal; Obesity; Rats; Rats, Zucker

2004
Dominant negative protein kinase Cbeta improves 1alpha, 25-dihydroxy vitamin D3-induced insulin resistance.
    Endocrine research, 2003, Volume: 29, Issue:4

    Topics: Adipocytes; Animals; Biological Transport; Deoxyglucose; Enzyme Inhibitors; Gene Expression; Genes, Dominant; Insulin; Insulin Resistance; Mutation; Protein Kinase C; Protein Kinase C beta; Rats; Swine; Vitamin D

2003
Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance.
    Endocrinology, 2004, Volume: 145, Issue:5

    Topics: 3-Hydroxybutyric Acid; Adiponectin; Adipose Tissue; Animals; Blood Glucose; Deoxyglucose; Fasting; Female; Food; Gene Expression; Glucose Intolerance; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Hexosamines; Humans; Insulin; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Skeletal; Proteins; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transcription Factors; Triglycerides

2004
Combination of metformin and thiazolidindiones restore insulin signalling in insulin-resistant cultured myotubes.
    Life sciences, 2004, Feb-27, Volume: 74, Issue:15

    Topics: Animals; Blotting, Western; Cells, Cultured; Creatine Kinase; Deoxyglucose; Drug Synergism; Insulin Receptor Substrate Proteins; Insulin Resistance; Metformin; Mice; Muscle Fibers, Skeletal; Phosphoproteins; Phosphorylation; Precipitin Tests; Receptor, Insulin; Thiazolidinediones

2004
Effects of rexinoids on glucose transport and insulin-mediated signaling in skeletal muscles of diabetic (db/db) mice.
    The Journal of biological chemistry, 2004, May-07, Volume: 279, Issue:19

    Topics: Acyl Coenzyme A; Animals; Anticholesteremic Agents; Biological Transport; Blotting, Western; Body Weight; Cattle; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose; Insulin; Insulin Resistance; Ligands; Ligases; Mice; Muscle, Skeletal; Muscles; Organic Chemicals; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-cbl; Receptor, Insulin; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transcription Factors; Triglycerides; Tyrosine; Ubiquitin-Protein Ligases

2004
Hexosamines are unlikely to function as a nutrient-sensor in 3T3-L1 adipocytes: a comparison of UDP-hexosamine levels after increased glucose flux and glucosamine treatment.
    Endocrine, 2004, Volume: 23, Issue:1

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Deoxyglucose; Glucosamine; Glucose; Hexosamines; Insulin; Insulin Resistance; Mice; Uridine Diphosphate Glucose; Uridine Diphosphate N-Acetylgalactosamine; Uridine Diphosphate N-Acetylglucosamine

2004
Angiotensin II type-1 receptor blocker valsartan enhances insulin sensitivity in skeletal muscles of diabetic mice.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Crosses, Genetic; Deoxyglucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Energy Intake; Gene Expression Regulation; Glucose Transporter Type 4; Imidazoles; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Obese; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Pyridines; Signal Transduction; Superoxides; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan

2004
Loss-of-function mutation of the galanin gene is associated with perturbed islet function in mice.
    Endocrinology, 2004, Volume: 145, Issue:7

    Topics: Animals; Antimetabolites; Body Weight; Deoxyglucose; Galanin; Glucagon; Glucose; Glucose Clamp Technique; Hyperinsulinism; Hypoglycemic Agents; Immunohistochemistry; Insulin; Insulin Resistance; Islets of Langerhans; Mice; Mice, Inbred Strains; Mice, Knockout; Sympathetic Nervous System

2004
Long-term exercise down-regulates leptin receptor mRNA in the arcuate nucleus.
    Neuroreport, 2004, Mar-22, Volume: 15, Issue:4

    Topics: Adipose Tissue; Animals; Arcuate Nucleus of Hypothalamus; Deoxyglucose; Down-Regulation; Glucose; Insulin Resistance; Leptin; Male; Muscle, Skeletal; Physical Conditioning, Animal; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Leptin; RNA, Messenger; Time

2004
Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation.
    The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26

    Topics: Adenoviridae; Animals; Carnitine O-Palmitoyltransferase; Cells, Cultured; Deoxyglucose; Fatty Acids; Glucose; Glycogen; Insulin; Insulin Resistance; Isoenzymes; Lipid Metabolism; Muscle Fibers, Skeletal; Oxidation-Reduction; Palmitates; Rats; RNA, Messenger; Signal Transduction; Transduction, Genetic

2004
Insulin resistance in adult cardiomyocytes undergoing dedifferentiation: role of GLUT4 expression and translocation.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:7

    Topics: Animals; Atrial Natriuretic Factor; Biological Transport, Active; Calcium Channel Blockers; Cell Differentiation; Cell Size; Cells, Cultured; Deoxyglucose; Diacetyl; Enzyme Activation; Gene Expression Regulation; Glucose Transporter Type 1; Glucose Transporter Type 4; Insulin; Insulin Resistance; Monosaccharide Transport Proteins; Muscle Proteins; Myocardial Contraction; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-cbl; Rats; RNA, Messenger; Sarcolemma; Ubiquitin-Protein Ligases; Verapamil

2004
Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease.
    The Journal of biological chemistry, 2004, Jul-30, Volume: 279, Issue:31

    Topics: Animals; Blotting, Western; Cell Membrane; Cytosol; Deoxyglucose; Enzyme Activation; Fatty Acids; Fatty Liver; Glycogen; Glycogen Synthase; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Male; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Phosphorylation; Precipitin Tests; Protein Isoforms; Protein Kinase C; Protein Kinase C-epsilon; Protein Transport; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Time Factors; Tyrosine

2004
Nelfinavir-induced insulin resistance is associated with impaired plasma membrane recruitment of the PI 3-kinase effectors Akt/PKB and PKC-zeta.
    Diabetologia, 2004, Volume: 47, Issue:6

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; 3T3-L1 Cells; Animals; Cell Membrane; Deoxyglucose; Drug Evaluation, Preclinical; Female; Glucose; Insulin Resistance; Japan; Mice; Nelfinavir; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphoinositide-3 Kinase Inhibitors; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Time Factors

2004
Glucosamine-induced insulin resistance in L6 muscle cells.
    Diabetes, obesity & metabolism, 2004, Volume: 6, Issue:4

    Topics: Animals; Cells, Cultured; Deoxyglucose; Dose-Response Relationship, Drug; Glucosamine; Insulin; Insulin Resistance; Muscle Cells; Rats

2004
Skeletal muscle contraction stimulates capillary recruitment and glucose uptake in insulin-resistant obese Zucker rats.
    American journal of physiology. Endocrinology and metabolism, 2004, Volume: 287, Issue:4

    Topics: Animals; Antimetabolites; Blood Glucose; Body Weight; Capillaries; Deoxyglucose; Electric Stimulation; Glucose; Hemodynamics; Hindlimb; Insulin Resistance; Male; Muscle Contraction; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Regional Blood Flow; Xanthines

2004
Topiramate is an insulin-sensitizing compound in vivo with direct effects on adipocytes in female ZDF rats.
    American journal of physiology. Endocrinology and metabolism, 2005, Volume: 288, Issue:3

    Topics: Adipocytes; Adiponectin; Adipose Tissue; Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Deoxyglucose; Eating; Fatty Acids, Nonesterified; Female; Fructose; Glucose; Glucose Tolerance Test; Insulin; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Leptin; Liver; Muscle, Skeletal; Ovary; Rats; Rats, Zucker; Topiramate

2005
GSK3 involvement in amylin signaling in isolated rat soleus muscle.
    Peptides, 2004, Volume: 25, Issue:12

    Topics: Amyloid; Animals; Calcitonin Gene-Related Peptide; Cyclic AMP; Deoxyglucose; Glycogen; Glycogen Synthase Kinase 3; In Vitro Techniques; Insulin Resistance; Islet Amyloid Polypeptide; Muscle, Skeletal; Rats

2004
Akt mediates the cross-talk between beta-adrenergic and insulin receptors in neonatal cardiomyocytes.
    Circulation research, 2005, Feb-04, Volume: 96, Issue:2

    Topics: Adrenergic beta-Agonists; Amino Acid Substitution; Animals; Animals, Newborn; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Deoxyglucose; Enzyme Activation; Insulin Resistance; Isoproterenol; Mice; Mice, Transgenic; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Receptor Cross-Talk; Receptor, Insulin; Receptors, Adrenergic, beta; Signal Transduction; Structure-Activity Relationship; Sympathetic Nervous System

2005
Inhibition of endogenous SHIP2 ameliorates insulin resistance caused by chronic insulin treatment in 3T3-L1 adipocytes.
    Diabetologia, 2005, Volume: 48, Issue:2

    Topics: 3T3 Cells; Adipocytes; Animals; Biological Transport; Deoxyglucose; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Isoenzymes; Mice; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoproteins; Phosphoric Monoester Hydrolases; Protein Kinase C; Signal Transduction; Sirolimus; src Homology Domains

2005
Muscle-specific Pten deletion protects against insulin resistance and diabetes.
    Molecular and cellular biology, 2005, Volume: 25, Issue:3

    Topics: Animals; Deoxyglucose; Diabetes Mellitus; Hyperinsulinism; Insulin; Insulin Resistance; Islets of Langerhans; Mice; Mice, Knockout; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoric Monoester Hydrolases; Phosphorylation; PTEN Phosphohydrolase; Tumor Suppressor Proteins

2005
Another role for the celebrity: Akt and insulin resistance.
    Circulation research, 2005, Feb-04, Volume: 96, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Deoxyglucose; Enzyme Activation; Humans; Insulin Resistance; Isoproterenol; MAP Kinase Signaling System; Mice; Models, Biological; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Receptor Cross-Talk; Receptor, Insulin; Receptors, Adrenergic, beta; Signal Transduction; Structure-Activity Relationship

2005
Potential involvement of adipocyte insulin resistance in obesity-associated up-regulation of adipocyte lysophospholipase D/autotaxin expression.
    Diabetologia, 2005, Volume: 48, Issue:3

    Topics: Adipocytes; Animals; Biological Transport; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Glucose-6-Phosphate Isomerase; Glycoproteins; Humans; Insulin Resistance; Lipectomy; Mice; Mice, Inbred C57BL; Multienzyme Complexes; Obesity; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases

2005
Cellular insulin resistance in Epstein-Barr virus-transformed lymphoblasts from young insulin-resistant Japanese men.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:3

    Topics: Adult; Blood Glucose; Body Mass Index; Cell Division; Cell Line, Transformed; Cholesterol; Cholesterol, LDL; Deoxyglucose; Herpesvirus 4, Human; Homeostasis; Humans; Hypertension; Insulin; Insulin Resistance; Lymphocytes; Male; Monosaccharide Transport Proteins

2005
Depletion of mitochondrial DNA causes impaired glucose utilization and insulin resistance in L6 GLUT4myc myocytes.
    The Journal of biological chemistry, 2005, Mar-18, Volume: 280, Issue:11

    Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Membrane; Cell Nucleus; Deoxyglucose; DNA Primers; DNA, Mitochondrial; Ethidium; Glucose; Glucose Transporter Type 4; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Monosaccharide Transport Proteins; Muscle Cells; Muscle Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Time Factors

2005
Calorie restriction improves whole-body glucose disposal and insulin resistance in association with the increased adipocyte-specific GLUT4 expression in Otsuka Long-Evans Tokushima fatty rats.
    Archives of biochemistry and biophysics, 2005, Apr-15, Volume: 436, Issue:2

    Topics: Adipocytes; Adipose Tissue; Animals; Biological Transport; Blood Glucose; Body Weight; Caloric Restriction; Cell Membrane; Cells, Cultured; Deoxyglucose; Glucose; Glucose Tolerance Test; Glucose Transporter Type 4; Hyperglycemia; Insulin; Insulin Resistance; Liver; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Protein Transport; Rats; Rats, Long-Evans; Time Factors

2005
Age and muscle-type modulated role of intramyocellular lipids in the progression of insulin resistance in nondiabetic Zucker rats.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:4

    Topics: Aging; Animals; Biological Transport; Blood Glucose; Deoxyglucose; Glucose Tolerance Test; Glycolysis; Insulin; Insulin Resistance; Kinetics; Lipids; Muscle Cells; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Obesity; Rats; Rats, Zucker

2005
High-fat diet induces increased tissue expression of TNF-alpha.
    Life sciences, 2005, Sep-09, Volume: 77, Issue:17

    Topics: Adipose Tissue; Animals; Blood Glucose; Blotting, Western; Deoxyglucose; Dietary Fats; Fatty Acids, Nonesterified; Glucose Tolerance Test; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Obesity; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2005
O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes.
    Experimental & molecular medicine, 2005, Jun-30, Volume: 37, Issue:3

    Topics: Acetylglucosamine; Adipocytes; Animals; beta-N-Acetylhexosaminidases; Deoxyglucose; Glucose Transporter Type 5; Glycosylation; Immunoprecipitation; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Monosaccharide Transport Proteins; Oximes; Phenylcarbamates; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Subcellular Fractions

2005
JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes.
    The Journal of biological chemistry, 2005, Oct-21, Volume: 280, Issue:42

    Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Biological Transport; Blotting, Western; Cell Differentiation; Deoxyglucose; Down-Regulation; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Fatty Acids, Nonesterified; Genes, Dominant; Glucose; Glucose Transporter Type 4; I-kappa B Kinase; Inflammation; Insulin; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Lipids; MAP Kinase Kinase 4; Mice; Protein Transport; RNA Interference; Signal Transduction; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Time Factors; Tumor Necrosis Factor-alpha

2005
Conjugated linoleic acid promotes human adipocyte insulin resistance through NFkappaB-dependent cytokine production.
    The Journal of biological chemistry, 2005, Nov-18, Volume: 280, Issue:46

    Topics: Active Transport, Cell Nucleus; Adipocytes; Butadienes; Cell Differentiation; Cell Membrane; Cell Nucleus; Cells, Cultured; Cytokines; Cytoplasm; Deoxyglucose; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fatty Acids; Glucose; Glucose Transporter Type 4; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Interleukin-6; Interleukin-8; Linoleic Acids, Conjugated; MAP Kinase Kinase Kinases; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; NF-kappa B; Nitriles; Phosphoproteins; Phosphorylation; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Time Factors; Transcription Factor RelA; Transfection; Triglycerides; Tumor Necrosis Factor-alpha

2005
Insulin-like growth factor binding protein-3 leads to insulin resistance in adipocytes.
    The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:12

    Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Biological Transport; Cell Membrane; Deoxyglucose; Glucose Transporter Type 4; Humans; In Vitro Techniques; Insulin; Insulin Resistance; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Mice; Omentum; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptor, Insulin; Recombinant Proteins; Subcutaneous Tissue

2005
Effect of leptin on insulin resistance of muscle--direct or indirect?
    Physiological research, 2006, Volume: 55, Issue:4

    Topics: Abdominal Fat; Animals; Appetite; Blood Glucose; Body Weight; Deoxyglucose; Dietary Fats; Eating; Insulin Resistance; Leptin; Male; Muscle, Skeletal; Rats; Rats, Wistar; Triglycerides

2006
Direct comparison of the acute in vivo effects of HIV protease inhibitors on peripheral glucose disposal.
    Journal of acquired immune deficiency syndromes (1999), 2005, Dec-01, Volume: 40, Issue:4

    Topics: Adipocytes; Animals; Atazanavir Sulfate; Carbamates; Deoxyglucose; Dose-Response Relationship, Drug; Furans; Glucose; Glucose Clamp Technique; HIV Protease Inhibitors; Infusions, Intravenous; Insulin Resistance; Lopinavir; Male; Models, Animal; Muscle, Skeletal; Myocardium; Oligopeptides; Pyridines; Pyrimidinones; Rats; Ritonavir; Sulfonamides

2005
Neurogenic insulin resistance in guinea-pigs with cisplatin-induced neuropathy.
    European journal of pharmacology, 2006, Feb-15, Volume: 531, Issue:1-3

    Topics: Acetylcholine; Animals; Antineoplastic Agents; Atropine; Blood Glucose; Body Weight; Calcitonin Gene-Related Peptide; Capsaicin; Celiac Plexus; Cisplatin; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose Clamp Technique; Guinea Pigs; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Peripheral Nervous System Diseases; Vasodilator Agents

2006
Effects of high-sucrose feeding on insulin resistance and hemodynamic responses to insulin in spontaneously hypertensive rats.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:6

    Topics: Animals; Blotting, Western; Deoxyglucose; Dose-Response Relationship, Drug; Endothelin-1; Fructose; Glucose Clamp Technique; Hemodynamics; Hyperinsulinism; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regional Blood Flow; Sucrose

2006
Overexpression of Rad in muscle worsens diet-induced insulin resistance and glucose intolerance and lowers plasma triglyceride level.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Mar-21, Volume: 103, Issue:12

    Topics: Amino Acids; Animals; Biological Transport; Creatine Kinase; Deoxyglucose; Diabetes Mellitus, Type 2; Dietary Fats; Enhancer Elements, Genetic; Glucose; Glucose Intolerance; Homeostasis; Insulin; Insulin Resistance; Lipid Metabolism; Lipoprotein Lipase; Mice; Mice, Transgenic; Muscle, Skeletal; Promoter Regions, Genetic; ras Proteins; Transcriptional Activation; Triglycerides; Up-Regulation

2006
Amino acids require glucose to enhance, through phosphoinositide-dependent protein kinase 1, the insulin-activated protein kinase B cascade in insulin-resistant rat adipocytes.
    Diabetologia, 2006, Volume: 49, Issue:5

    Topics: Adipocytes; Amino Acids; Androstadienes; Animals; Biological Transport; Deoxyglucose; Glucose; Insulin Resistance; Male; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Wortmannin

2006
TNF and TNF receptor expression and insulin sensitivity in human omental and subcutaneous adipose tissue--influence of BMI and adipose distribution.
    Diabetes & vascular disease research, 2006, Volume: 3, Issue:1

    Topics: Abdominal Fat; Adipocytes; Adult; Aged; Body Fat Distribution; Body Mass Index; Deoxyglucose; Female; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha; Waist-Hip Ratio

2006
Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance.
    The Journal of biological chemistry, 2006, Sep-08, Volume: 281, Issue:36

    Topics: Adipose Tissue; Animals; Antimetabolites; Body Weight; Cells, Cultured; Chemokine CCL2; Deoxyglucose; Diet; Dietary Fats; Fatty Acid-Binding Proteins; Fatty Acids, Nonesterified; Glucose; Glucose Clamp Technique; Insulin; Insulin Resistance; Interleukin-6; Macrophages; Mice; Mice, Inbred C57BL; Mice, Obese; Mice, Transgenic; Myoblasts, Skeletal; Promoter Regions, Genetic; Signal Transduction; Tumor Necrosis Factor-alpha

2006
How muscle insulin sensitivity is regulated: testing of a hypothesis.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 291, Issue:6

    Topics: Animals; Antimetabolites; Biological Transport, Active; Deoxyglucose; Glucose; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Wistar; Signal Transduction; Swimming

2006
Transferrin and iron induce insulin resistance of glucose transport in adipocytes.
    Metabolism: clinical and experimental, 2006, Volume: 55, Issue:8

    Topics: Adipocytes; Animals; Biological Transport, Active; Cell Separation; Culture Media, Serum-Free; Deoxyglucose; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Glucose; In Vitro Techniques; Insulin Resistance; Iron; Lipolysis; Male; Rats; Rats, Sprague-Dawley; Transferrin

2006
Apoptosis in skeletal muscle myotubes is induced by ceramides and is positively related to insulin resistance.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 291, Issue:6

    Topics: Acyl Coenzyme A; Animals; Antimetabolites; Apoptosis; Blotting, Western; Caspase 3; Ceramides; Deoxyglucose; DNA Fragmentation; Dose-Response Relationship, Drug; Fatty Acids; Flow Cytometry; Glucose; Hypoglycemic Agents; Insulin; Insulin Resistance; Microscopy, Fluorescence; Muscle Fibers, Skeletal; Muscle, Skeletal; Palmitoyl Coenzyme A; Rats; RNA, Small Interfering; Signal Transduction

2006
Estrogen receptor alpha regulates insulin sensitivity through IRS-1 tyrosine phosphorylation in mature 3T3-L1 adipocytes.
    Endocrine journal, 2006, Volume: 53, Issue:6

    Topics: 3T3-L1 Cells; Animals; Deoxyglucose; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Phenols; Phosphoproteins; Phosphorylation; Piperazine; Piperazines; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pyrazoles; Suppressor of Cytokine Signaling Proteins

2006
Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acid-induced skeletal muscle insulin resistance in vitro.
    Diabetologia, 2006, Volume: 49, Issue:12

    Topics: Animals; Deoxyglucose; Fatty Acids; Gene Expression Regulation, Enzymologic; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Muscle Fibers, Skeletal; Muscle, Skeletal; Obesity; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Stearoyl-CoA Desaturase; Transfection

2006
A Lupinoside prevented fatty acid induced inhibition of insulin sensitivity in 3T3 L1 adipocytes.
    Molecular and cellular biochemistry, 2007, Volume: 300, Issue:1-2

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Deoxyglucose; Glucose Transporter Type 4; Green Fluorescent Proteins; Insulin; Insulin Resistance; Male; Mice; Palmitates; Phytotherapy; Plant Extracts; Pueraria; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Saponins; Signal Transduction

2007
Role of glycogen content in insulin resistance in human muscle cells.
    Journal of cellular physiology, 2007, Volume: 211, Issue:2

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinase Kinases; Cells, Cultured; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme Activation; Glucose; Glycogen; Glycogen Synthase; Glycogen Synthase Kinase 3; Humans; Insulin; Insulin Resistance; Myoblasts, Skeletal; Phosphorylation; Protein Kinases; Protein Transport; Proto-Oncogene Proteins c-akt; Ribonucleotides; Signal Transduction; Time Factors

2007
Assessment of insulin resistance in fructose-fed rats with 125I-6-deoxy-6-iodo-D-glucose, a new tracer of glucose transport.
    European journal of nuclear medicine and molecular imaging, 2007, Volume: 34, Issue:5

    Topics: Animals; Biological Transport; Deoxyglucose; Diagnostic Imaging; Fructose; Glucose; Image Processing, Computer-Assisted; Insulin; Insulin Resistance; Iodine Radioisotopes; Male; Models, Biological; Models, Theoretical; Rats; Rats, Wistar

2007
MAP4K4 gene silencing in human skeletal muscle prevents tumor necrosis factor-alpha-induced insulin resistance.
    The Journal of biological chemistry, 2007, Mar-16, Volume: 282, Issue:11

    Topics: Cell Differentiation; Deoxyglucose; Gene Silencing; Humans; Insulin Resistance; Interleukin-6; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle Fibers, Skeletal; Muscle, Skeletal; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; Tumor Necrosis Factor-alpha

2007
Increased insulin sensitivity and reduced micro and macro vascular disease induced by 2-deoxy-D-glucose during metabolic syndrome in obese JCR: LA-cp rats.
    British journal of pharmacology, 2007, Volume: 151, Issue:2

    Topics: Acetylcholine; Adiponectin; Animals; Blood Glucose; Body Weight; Deoxyglucose; Dose-Response Relationship, Drug; Eating; Female; In Vitro Techniques; Insulin Resistance; Leptin; Male; Metabolic Syndrome; Nitroprusside; Obesity; Phenylephrine; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Renal Circulation; Time Factors; Vascular Diseases; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents

2007
Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance.
    The Journal of biological chemistry, 2007, May-18, Volume: 282, Issue:20

    Topics: Adenoviridae; Animals; Deoxyglucose; Fatty Liver; Gene Expression; Glycerol-3-Phosphate O-Acyltransferase; Glycogen; Hyperlipidemias; Insulin Resistance; Interleukin-1beta; Lipid Metabolism; Liver; Male; Muscle, Skeletal; NF-kappa B; Protein Kinase C-epsilon; Rats; Rats, Wistar; Transduction, Genetic; Triglycerides; Tumor Necrosis Factor-alpha

2007
Crocetin attenuates palmitate-induced insulin insensitivity and disordered tumor necrosis factor-alpha and adiponectin expression in rat adipocytes.
    British journal of pharmacology, 2007, Volume: 151, Issue:5

    Topics: Acetylcysteine; Adipocytes; Adiponectin; Animals; Antimetabolites; Antioxidants; Blotting, Western; Carotenoids; Deoxyglucose; Glucose; Glucose Transporter Type 4; Insulin Resistance; Male; Onium Compounds; Palmitates; Rats; Rats, Wistar; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Vitamin A

2007
In vivo assessment of cardiac insulin resistance by nuclear probes using an iodinated tracer of glucose transport.
    European journal of nuclear medicine and molecular imaging, 2007, Volume: 34, Issue:11

    Topics: Animals; Biological Transport, Active; Deoxyglucose; Glucose; Heart; Image Interpretation, Computer-Assisted; Insulin Resistance; Iodine Radioisotopes; Male; Molecular Probe Techniques; Myocardium; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Rats, Zucker

2007
Calreticulin and Hsp90 stabilize the human insulin receptor and promote its mobility in the endoplasmic reticulum.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Jun-19, Volume: 104, Issue:25

    Topics: Antigens, CD; Antimetabolites; Calreticulin; Cell Line; Deoxyglucose; Endoplasmic Reticulum; Enzyme Inhibitors; Green Fluorescent Proteins; HSP90 Heat-Shock Proteins; Humans; Indolizines; Insulin Resistance; Molecular Chaperones; Mutation, Missense; Proteasome Endopeptidase Complex; Protein Folding; Protein Structure, Tertiary; Receptor, Insulin; Recombinant Fusion Proteins; Time Factors

2007
Berberine improves glucose metabolism through induction of glycolysis.
    American journal of physiology. Endocrinology and metabolism, 2008, Volume: 294, Issue:1

    Topics: 3T3-L1 Cells; Adenosine Monophosphate; Adenosine Triphosphate; Adipocytes; AMP-Activated Protein Kinases; Animals; Berberine; Deoxyglucose; Diabetes Mellitus, Type 2; Drugs, Chinese Herbal; Glucose; Glucose Intolerance; Glycolysis; Insulin Resistance; Lactic Acid; Male; Mice; Mitochondria; Multienzyme Complexes; Obesity; Oxygen Consumption; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Wistar

2008
Effect of a low magnesium diet on in vitro glucose uptake in sucrose fed rats.
    Magnesium research, 2007, Volume: 20, Issue:3

    Topics: Animals; Blood Glucose; Deoxyglucose; Diaphragm; Dietary Carbohydrates; Erythrocytes; Glucose; In Vitro Techniques; Insulin; Insulin Resistance; Liver; Magnesium; Male; Muscle, Skeletal; Rats; Rats, Wistar; Sucrose; Time Factors

2007
HIV protease inhibitors that block GLUT4 precipitate acute, decompensated heart failure in a mouse model of dilated cardiomyopathy.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, Volume: 22, Issue:7

    Topics: Animals; Atazanavir Sulfate; Blood Glucose; Cardiomyopathy, Dilated; Deoxyglucose; Disease Models, Animal; Echocardiography; Glucose Tolerance Test; Glucose Transporter Type 4; Heart Failure; HIV Protease Inhibitors; Humans; Insulin Resistance; Lopinavir; Mice; Myocardium; Oligopeptides; Pulmonary Edema; Pyridines; Pyrimidinones

2008
Utilization of fluorescence tracer in hyperinsulinemic-euglycemic clamp test in mice.
    Journal of biochemical and biophysical methods, 2008, Apr-24, Volume: 70, Issue:6

    Topics: 4-Chloro-7-nitrobenzofurazan; Animal Feed; Animals; Blood Glucose; Deoxyglucose; Female; Fluorescent Dyes; Glucose Clamp Technique; Hyperinsulinism; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Organ Specificity

2008
IL-12 serum levels in patients with type 2 diabetes treated with sulphonylureas.
    Cytokine, 2008, Volume: 42, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; C-Peptide; Coronary Artery Disease; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Interleukin-12; Lipoproteins, HDL; Male; Middle Aged; Multivariate Analysis; Proinsulin; Regression Analysis; Sulfonylurea Compounds

2008
Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice.
    Diabetologia, 2008, Volume: 51, Issue:7

    Topics: Adenylate Kinase; Adipose Tissue; Animals; Body Weight; Chimera; Cytomegalovirus; Deoxyglucose; Gene Expression; Glucose; Glucose Transporter Type 4; Hepatitis; Hyperinsulinism; Insulin Resistance; Interleukin-6; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscle, Skeletal; Phosphorylation

2008
The anti-diabetic properties of Guazuma ulmifolia Lam are mediated by the stimulation of glucose uptake in normal and diabetic adipocytes without inducing adipogenesis.
    Journal of ethnopharmacology, 2008, Jul-23, Volume: 118, Issue:2

    Topics: 3T3 Cells; 4-Chloro-7-nitrobenzofurazan; Adipocytes; Adipogenesis; Animals; Deoxyglucose; Dose-Response Relationship, Drug; Glucose; Hypoglycemic Agents; Insulin; Insulin Resistance; Malvaceae; Medicine, Traditional; Mexico; Mice; Plant Extracts; Triglycerides

2008
Mechanisms of insulin resistance in cultured fibroblasts from a patient with leprechaunism: impaired post-binding actions of insulin and multiplication-stimulating activity.
    Metabolism: clinical and experimental, 1984, Volume: 33, Issue:12

    Topics: Adult; Aminoisobutyric Acids; Cells, Cultured; Child, Preschool; Deoxyglucose; Endocrine System Diseases; Enzyme Activation; Face; Female; Fibroblasts; Glycogen Synthase; Humans; Insulin; Insulin Resistance; Insulin-Like Growth Factor II; Male; Peptides; Receptor, Insulin; Receptors, Cell Surface; Receptors, Somatomedin; Syndrome

1984
Membrane structural/functional properties of adipocytes from normal and streptozotocin-diabetic rats.
    Diabetes, 1984, Volume: 33, Issue:3

    Topics: Adipose Tissue; Animals; Cell Membrane; Deoxyglucose; Diabetes Mellitus, Experimental; Electron Spin Resonance Spectroscopy; Glucose; Insulin; Insulin Resistance; Male; Rats; Rats, Inbred Strains; Temperature

1984
Characterization of the serum from a patient with insulin resistance and hypoglycemia. Evidence for multiple populations of insulin receptor antibodies with different receptor binding and insulin-mimicking activities.
    Diabetes, 1984, Volume: 33, Issue:3

    Topics: Adipose Tissue; Animals; Antibodies, Monoclonal; Autoantibodies; Deoxyglucose; Female; Humans; Hypoglycemia; Immunoglobulin G; Insulin; Insulin Resistance; Lymphocytes; Mice; Rats; Receptor, Insulin

1984
Antibody against the insulin receptor causes disappearance of insulin receptors in 3T3-L1 cells: a possible explanation of antibody-induced insulin resistance.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:8

    Topics: Animals; Antigen-Antibody Complex; Autoantibodies; Biological Transport, Active; Cells, Cultured; Deoxyglucose; Insulin; Insulin Resistance; Kinetics; Rats; Receptor, Insulin

1984
A new form of insulin resistance with growth retardation, fatty liver, and hypogonadotropic hypogonadism.
    Pediatric research, 1984, Volume: 18, Issue:7

    Topics: Adolescent; Cells, Cultured; Deoxyglucose; Erythrocytes; Fatty Liver; Fibroblasts; Growth Disorders; Humans; Hypogonadism; Insulin; Insulin Resistance; Male; Receptor, Insulin; Thymidine

1984
Defect in insulin receptor of experimental uremic rat.
    Nihon Jinzo Gakkai shi, 1984, Volume: 26, Issue:9

    Topics: Adipose Tissue; Animals; Deoxyglucose; Erythrocytes; Insulin; Insulin Resistance; Male; Rats; Rats, Inbred Strains; Receptor, Insulin; Time Factors; Uremia

1984
The development of insulin resistance in brown adipose tissue may impair the acute cold-induced activation of thermogenesis in genetically obese (ob/ob) mice.
    Bioscience reports, 1984, Volume: 4, Issue:11

    Topics: Adipose Tissue, Brown; Aging; Animals; Body Temperature Regulation; Cold Temperature; Deoxyglucose; Guanosine Diphosphate; Insulin; Insulin Resistance; Lipids; Male; Mice; Mice, Obese; Mitochondria; Species Specificity

1984
Adrenalectomy reverses insulin resistance in muscle from obese (ob/ob) mice.
    The American journal of physiology, 1984, Volume: 246, Issue:2 Pt 1

    Topics: Adrenal Glands; Adrenalectomy; Animals; Biological Transport; Blood Glucose; Deoxyglucose; Glycogen Synthase; Hindlimb; Insulin Resistance; Male; Mice; Mice, Obese; Muscles; Perfusion

1984
Insulin resistance of denervated rat muscle: a model for impaired receptor-function coupling.
    The American journal of physiology, 1984, Volume: 247, Issue:5 Pt 1

    Topics: Animals; Deoxyglucose; Epinephrine; Glucose; Glucose-6-Phosphate; Glucosephosphates; Glycogen; Glycogen Synthase; Insulin; Insulin Resistance; Male; Muscle Denervation; Muscles; Rats; Rats, Inbred Strains; Receptor, Insulin; Sciatic Nerve; Time Factors

1984
Insulin-stimulated glucose transport in cultured fibroblasts from normal and noninsulin-dependent (type II) diabetic human subjects.
    The Journal of clinical endocrinology and metabolism, 1982, Volume: 55, Issue:6

    Topics: Adult; Biological Transport; Cells, Cultured; Deoxyglucose; Diabetes Mellitus; Female; Fibroblasts; Glucose; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Receptor, Insulin

1982
Autoantibodies to the insulin receptor and insulin-resistant diabetes.
    Hormone research, 1982, Volume: 16, Issue:5

    Topics: Adipose Tissue; Adolescent; Adult; Aged; Autoantibodies; Deoxyglucose; Diabetes Mellitus; Female; Fibroblasts; Humans; Insulin; Insulin Resistance; Liver; Male; Middle Aged; Muscles; Receptor, Insulin

1982
Decreased insulin binding, glucose transport, and glucose metabolism in soleus muscle of rats fed a high fat diet.
    Diabetes, 1982, Volume: 31, Issue:3

    Topics: Animals; Biological Transport; Deoxyglucose; Dietary Fats; Female; Glucose; Insulin; Insulin Resistance; Male; Muscles; Rats; Rats, Zucker; Receptor, Insulin

1982
Type II diabetes and insulin resistance. Evidence of lack of inherent cellular defects in insulin sensitivity.
    Diabetes, 1981, Volume: 30, Issue:7

    Topics: Adult; Blood Glucose; Cell Line; Deoxyglucose; Diabetes Mellitus; Female; Fibroblasts; Glycogen Synthase; Hexoses; Humans; Insulin; Insulin Resistance; Male; Middle Aged

1981
Insulin resistance in soleus muscle from obese Zucker rats. Involvement of several defective sites.
    The Biochemical journal, 1980, Feb-15, Volume: 186, Issue:2

    Topics: Animals; Deoxyglucose; Female; Glucose; Glycogen; Glycolysis; In Vitro Techniques; Insulin; Insulin Resistance; Intracellular Fluid; Muscles; Obesity; Oxygen Consumption; Rats; Receptor, Insulin

1980
Age-dependent development of insulin resistance of soleus muscle in genetically obese (ob/ob) mice.
    The American journal of physiology, 1980, Volume: 239, Issue:5

    Topics: Aging; Animals; Biological Transport; Cell Membrane; Deoxyglucose; Female; Glucose; Insulin; Insulin Resistance; Male; Mice; Mice, Obese; Muscles; Receptor, Insulin

1980
Immunoreactivity and biologic activity of semisynthetic [LeuB-30]-insulin: potential value in the treatment of insulin antibody-mediated insulin resistance.
    Diabetes, 1981, Volume: 30, Issue:6

    Topics: Adipose Tissue; Animals; Antigen-Antibody Complex; Biological Transport, Active; Blood Glucose; Cell Membrane; Deoxyglucose; Female; Humans; Insulin; Insulin Antibodies; Insulin Resistance; Kinetics; Placenta; Pregnancy; Rats; Receptor, Insulin; Structure-Activity Relationship

1981
Glucocorticoid-induced insulin resistance in vitro: evidence for both receptor and postreceptor defects.
    Endocrinology, 1981, Volume: 109, Issue:5

    Topics: Animals; Biological Transport, Active; Cells, Cultured; Deoxyglucose; Dexamethasone; Glucocorticoids; Insulin; Insulin Resistance; Kinetics; Mice; Receptor, Insulin; Receptors, Glucocorticoid; Receptors, Steroid

1981
Evidence that stimulation of glucose metabolism by insulin is not altered in isolated soleus muscle of pregnant rats.
    The Biochemical journal, 1981, Oct-15, Volume: 200, Issue:1

    Topics: Animals; Deoxyglucose; Female; Glucose; In Vitro Techniques; Insulin; Insulin Resistance; Muscles; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Stimulation, Chemical

1981
Insulin resistance for glucose metabolism in disused soleus muscle of mice.
    The American journal of physiology, 1982, Volume: 242, Issue:1

    Topics: Anesthesia, General; Animals; Deoxyglucose; Glucose; Glycolysis; Immobilization; Insulin Resistance; Male; Mice; Muscles

1982
Fiber type-specific effects of clenbuterol and exercise training on insulin-resistant muscle.
    Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 79, Issue:1

    Topics: Animals; Citrate (si)-Synthase; Clenbuterol; Deoxyglucose; Female; Glucose Transporter Type 4; Insulin Resistance; Monosaccharide Transport Proteins; Muscle Fibers, Skeletal; Muscle Proteins; Muscles; Osmolar Concentration; Physical Conditioning, Animal; Rats; Rats, Zucker

1995
Characterization of insulin resistance and NIDDM in transgenic mice with reduced brown fat.
    Diabetes, 1995, Volume: 44, Issue:11

    Topics: Adipose Tissue; Adipose Tissue, Brown; Aging; Animals; Biological Transport; Blood Glucose; Cell Membrane; Deoxyglucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diphtheria Toxin; Female; Gene Expression; Glucose Tolerance Test; Glucose Transporter Type 4; Insulin; Insulin Resistance; Male; Mice; Mice, Transgenic; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Receptor, Insulin; Reference Values; RNA, Messenger; Sex Characteristics; Tumor Necrosis Factor-alpha

1995
Insulin action on heart and skeletal muscle glucose uptake in essential hypertension.
    The Journal of clinical investigation, 1995, Volume: 96, Issue:2

    Topics: Adult; Biological Transport, Active; Deoxyglucose; Female; Fluorodeoxyglucose F18; Glucose; Heart; Humans; Hypertension; Hypertrophy, Left Ventricular; Image Processing, Computer-Assisted; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Myocardium; Oxygen Consumption; Tomography, Emission-Computed; Ventricular Function, Left

1995
Glucocorticoid-induced insulin resistance: dexamethasone inhibits the activation of glucose transport in rat skeletal muscle by both insulin- and non-insulin-related stimuli.
    Diabetes, 1995, Volume: 44, Issue:4

    Topics: Animals; Biological Transport; Body Weight; Deoxyglucose; Dexamethasone; Glucose Transporter Type 4; Hypoxia; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscles; Rats; Rats, Sprague-Dawley

1995
Excessive glucose production, rather than insulin resistance, accounts for hyperglycaemia in recent-onset streptozotocin-diabetic rats.
    Diabetologia, 1995, Volume: 38, Issue:3

    Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Clamp Technique; Glycogen; Glycolysis; Hyperglycemia; Insulin; Insulin Resistance; Liver; Liver Glycogen; Male; Muscle, Skeletal; Myocardium; Organ Specificity; Rats; Rats, Wistar; Reference Values

1995
Okadaic acid, vanadate, and phenylarsine oxide stimulate 2-deoxyglucose transport in insulin-resistant human skeletal muscle.
    Diabetes, 1995, Volume: 44, Issue:6

    Topics: Adult; Animals; Arsenicals; Biological Transport; Deoxyglucose; Ethers, Cyclic; Humans; Insulin Resistance; Male; Muscle, Skeletal; Okadaic Acid; Phosphoprotein Phosphatases; Rats; Rats, Sprague-Dawley; Vanadates

1995
Hypoxia stimulates glucose transport in insulin-resistant human skeletal muscle.
    Diabetes, 1995, Volume: 44, Issue:6

    Topics: Adult; Biological Transport; Deoxyglucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucose; Humans; Hypoxia; Insulin; Insulin Resistance; Muscle, Skeletal; Obesity

1995
Insulin resistance and hypertension: studies in transgenic hypertensive TGR(mREN-2)27 rats.
    The American journal of physiology, 1994, Volume: 267, Issue:6 Pt 2

    Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Animals, Genetically Modified; Blood Glucose; Deoxyglucose; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Heterozygote; Hypertension; Insulin; Insulin Resistance; Muscles; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Renin; Triglycerides

1994
Neonatal monosodium glutamate treatment increases epididymal adipose tissue sensitivity to insulin in three-month old rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1994, Volume: 27, Issue:5

    Topics: Adipocytes; Adipose Tissue; Animals; Animals, Newborn; Deoxyglucose; Epididymis; Glucose; Insulin; Insulin Resistance; Male; Rats; Rats, Wistar; Sodium Glutamate

1994
Modifications of glucose and lipid metabolism in cold-acclimated lean and genetically obese rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 76, Issue:3

    Topics: Acclimatization; Adipose Tissue; Adipose Tissue, Brown; Animals; Blood Glucose; Cold Temperature; Deoxyglucose; Eating; Fatty Acids, Nonesterified; Glucose; Insulin Resistance; Lipid Metabolism; Liver; Male; Muscles; Obesity; Rats; Rats, Inbred Strains; Triglycerides; Weight Gain

1994
The regulation of insulin action in isolated adipocytes. Role of the periodicity of food intake, time of day and melatonin.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1994, Volume: 27, Issue:4

    Topics: Adipocytes; Animals; Deoxyglucose; Eating; Insulin; Insulin Resistance; Melatonin; Periodicity; Rats; Receptor, Insulin; Time Factors

1994
In vivo effects of insulin on tumor and skeletal muscle glucose metabolism in patients with lymphoma.
    Cancer, 1994, Mar-01, Volume: 73, Issue:5

    Topics: Adult; Aged; Deoxyglucose; Female; Fluorodeoxyglucose F18; Glucose; Glucose Clamp Technique; Hodgkin Disease; Humans; Insulin; Insulin Resistance; Lymphoma; Male; Middle Aged; Muscles; Tomography, Emission-Computed

1994
Saturated fatty acid-induced insulin resistance in rat adipocytes.
    Diabetes, 1994, Volume: 43, Issue:4

    Topics: Adipocytes; Animals; Biological Transport; Cells, Cultured; Deoxyglucose; Fatty Acids, Nonesterified; Glucose; Insulin; Insulin Resistance; Kinetics; Male; Palmitic Acid; Palmitic Acids; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1994
Time courses of changes in hepatic and skeletal muscle insulin action and GLUT4 protein in skeletal muscle after STZ injection.
    Diabetes, 1994, Volume: 43, Issue:4

    Topics: Animals; Blood Glucose; Deoxyglucose; Glucose; Glucose Clamp Technique; Glucose Transporter Type 4; Glycolysis; Hyperinsulinism; Insulin; Insulin Resistance; Kinetics; Liver; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscles; Rats; Rats, Wistar; Reference Values; Streptozocin; Time Factors

1994
Effects of systemic infusions of endotoxin, tumor necrosis factor, and interleukin-1 on glucose metabolism in the rat: relationship to endogenous glucose production and peripheral tissue glucose uptake.
    Metabolism: clinical and experimental, 1994, Volume: 43, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Deoxyglucose; Endotoxins; Glucose; Infusions, Intravenous; Injections, Intravenous; Insulin; Insulin Resistance; Interleukin-1; Liver; Male; Muscles; Rats; Rats, Sprague-Dawley; Tritium; Tumor Necrosis Factor-alpha

1994
Tissue [1-14C] 2-deoxyglucose metabolism in the gold thioglucose obese mouse: effects of 'dieting'.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1994, Volume: 18, Issue:3

    Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Aurothioglucose; Blood Glucose; Carbon Radioisotopes; Deoxyglucose; Diet, Reducing; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred CBA; Muscles; Myocardium; Obesity

1994
Nitrendipine improves glucose tolerance and deoxyglucose uptake in hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:6 Pt 2

    Topics: Animals; Blood Pressure; Deoxyglucose; Glucose; Glucose Tolerance Test; Hypertension; Insulin Resistance; Muscles; Nitrendipine; Rats; Rats, Inbred SHR; Regional Blood Flow

1994
The effects of oestrogen and progesterone on insulin sensitivity in female rats.
    Acta physiologica Scandinavica, 1993, Volume: 149, Issue:1

    Topics: Animals; Blood Glucose; Body Weight; Deoxyglucose; Estradiol; Estrogens; Female; Glycogen; Insulin; Insulin Resistance; Liver; Muscles; Organ Size; Ovariectomy; Progesterone; Rats; Rats, Sprague-Dawley

1993
Effect of acidosis on insulin binding and glucose uptake in isolated rat adipocytes.
    The Tohoku journal of experimental medicine, 1993, Volume: 169, Issue:3

    Topics: Acidosis; Adipocytes; Animals; Deoxyglucose; Glucose; In Vitro Techniques; Insulin; Insulin Resistance; Iodine Radioisotopes; Kinetics; Male; Rats; Rats, Sprague-Dawley; Receptor, Insulin

1993
Spaceflight on STS-48 and earth-based unweighting produce similar effects on skeletal muscle of young rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:5

    Topics: Animals; Atrophy; Deoxyglucose; Drinking; Eating; Female; Glucose; Insulin; Insulin Resistance; Muscle Denervation; Muscle Development; Muscle Proteins; Muscles; Organ Size; Rats; Space Flight; Weight Gain; Weightlessness

1993
Peripheral insulin resistance precedes the onset of hyperglycemia in spontaneously diabetic Chinese hamsters of Asahikawa colony.
    Diabetes research and clinical practice, 1993, Volume: 20, Issue:2

    Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Blood Glucose; Cricetinae; Cricetulus; Deoxyglucose; Diabetes Mellitus, Type 1; Epididymis; Female; Glucose; Glycated Hemoglobin; Hyperglycemia; Insulin; Insulin Resistance; Liver; Male; Organ Specificity; Prediabetic State; Reference Values

1993
Amylin and CGRP induce insulin resistance via a receptor distinct from cAMP-coupled CGRP receptor.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1

    Topics: Amyloid; Animals; Biological Transport; Calcitonin Gene-Related Peptide; Cell Line; Cyclic AMP; Deoxyglucose; Glycogen; Insulin; Insulin Resistance; Islet Amyloid Polypeptide; Kinetics; Male; Muscles; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Calcitonin; Receptors, Cell Surface

1993
Effects of thiazolidinediones on glucocorticoid-induced insulin resistance and GLUT4 glucose transporter expression in rat skeletal muscle.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:10

    Topics: Animals; Benzopyrans; Blood Glucose; Deoxyglucose; Dexamethasone; Glucocorticoids; Glucose Transporter Type 4; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Isomerism; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscles; Pioglitazone; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones; Tritium

1993
Electrical stimulation partly reverses the muscle insulin resistance caused by tenotomy.
    FEBS letters, 1993, Jan-04, Volume: 315, Issue:2

    Topics: Achilles Tendon; Animals; Biological Transport; Deoxyglucose; Electric Stimulation; Glycogen; Insulin Resistance; Lactates; Male; Movement; Muscles; Rats; Rats, Wistar

1993
In vivo glucose utilization by individual tissues in virgin and pregnant offspring of severely diabetic rats.
    Diabetes, 1993, Volume: 42, Issue:4

    Topics: Adipose Tissue; Analysis of Variance; Animals; Blood Glucose; Brain; Deoxyglucose; Diabetes Mellitus, Experimental; Duodenum; Female; Fetus; Glucose; Glucose Clamp Technique; Insulin; Insulin Resistance; Muscles; Placenta; Pregnancy; Pregnancy in Diabetics; Rats; Rats, Wistar; Reference Values

1993
Insulin resistance in liver cirrhosis. Positron-emission tomography scan analysis of skeletal muscle glucose metabolism.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:5

    Topics: Adult; Blood Glucose; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glucose; Humans; Insulin Resistance; Kinetics; Liver Cirrhosis; Male; Muscles; Oxygen Consumption; Reference Values; Tomography, Emission-Computed

1993
Insulin resistance is localized to skeletal but not heart muscle in type 1 diabetes.
    The American journal of physiology, 1993, Volume: 264, Issue:5 Pt 1

    Topics: Adult; Blood Glucose; C-Peptide; Deoxyglucose; Diabetes Mellitus, Type 1; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glucose; Glucose Clamp Technique; Glycated Hemoglobin; Heart; Humans; Infusions, Intravenous; Insulin; Insulin Resistance; Muscles; Myocardium; Organ Specificity; Reference Values; Tomography, Emission-Computed

1993
Dexamethasone-induced impairment in skeletal muscle glucose transport is not reversed by inhibition of free fatty acid oxidation.
    Metabolism: clinical and experimental, 1996, Volume: 45, Issue:1

    Topics: Animals; Biological Transport; Carnitine O-Palmitoyltransferase; Deoxyglucose; Dexamethasone; Epoxy Compounds; Fatty Acids, Nonesterified; Glucocorticoids; Glucose; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Oxidation-Reduction; Rats; Rats, Sprague-Dawley

1996
Metabolic impairment precedes insulin resistance in skeletal muscle during high-fat feeding in rats.
    Diabetes, 1996, Volume: 45, Issue:5

    Topics: Animals; Blood Glucose; Deoxyglucose; Diet, Fat-Restricted; Dietary Fats; Fatty Acids, Nonesterified; Glucose; Glucose Clamp Technique; Glycogen; Glycolysis; Insulin; Insulin Resistance; Kinetics; Male; Muscle, Skeletal; Rats; Rats, Wistar; Time Factors; Tritium

1996
Effect of glucose, insulin, and insulin-like growth factor-I on glucose transport activity in cultured rat vascular smooth muscle cells.
    Atherosclerosis, 1996, Nov-15, Volume: 127, Issue:1

    Topics: Androstadienes; Animals; Biological Transport; Cells, Cultured; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme Inhibitors; Follow-Up Studies; Glucose; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Male; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Wistar; Wortmannin

1996
Phosphatidylinositol 3-kinase and dynamics of insulin resistance in denervated slow and fast muscles in vivo.
    The American journal of physiology, 1997, Volume: 272, Issue:4 Pt 1

    Topics: Animals; Deoxyglucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Hindlimb; Insulin Resistance; Male; Monosaccharide Transport Proteins; Muscle Denervation; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle Proteins; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Sprague-Dawley; Receptor, Insulin; Time Factors

1997
Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance in multiple insulin sensitive tissues.
    Endocrinology, 1997, Volume: 138, Issue:6

    Topics: Adipose Tissue; Animals; Blood Glucose; Deoxyglucose; Glucosamine; Glucose; Glucose Clamp Technique; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Glycogen; Hexosamines; Hyperinsulinism; Infusions, Intravenous; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Myocardium; Rats; Rats, Wistar; Submandibular Gland

1997
Oxidant stress reduces insulin responsiveness in 3T3-L1 adipocytes.
    The American journal of physiology, 1997, Volume: 272, Issue:5 Pt 1

    Topics: 3T3 Cells; Adipocytes; Animals; Deoxyglucose; Dose-Response Relationship, Drug; Glucose Oxidase; Glycogen Synthase; Hydrogen Peroxide; Insulin; Insulin Resistance; Isoenzymes; Lipids; Mice; Oxidative Stress

1997
Lactate infusion in anesthetized rats produces insulin resistance in heart and skeletal muscles.
    Metabolism: clinical and experimental, 1997, Volume: 46, Issue:6

    Topics: Adipose Tissue; Anesthesia, General; Animals; Bicarbonates; Blood Glucose; Deoxyglucose; Glucose; Glucose Clamp Technique; Heart; Infusions, Intravenous; Insulin Resistance; Lactates; Male; Muscle, Skeletal; Myocardium; Rats; Rats, Sprague-Dawley

1997
Alterations in skeletal muscle protein-tyrosine phosphatase activity and expression in insulin-resistant human obesity and diabetes.
    The Journal of clinical investigation, 1997, Jul-15, Volume: 100, Issue:2

    Topics: Adult; Body Weight; Cell Fractionation; Chromatography, Gel; Deoxyglucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Immunoblotting; Insulin; Insulin Resistance; Middle Aged; Muramidase; Muscle, Skeletal; Obesity; Phosphoprotein Phosphatases; Phosphorylation; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptor, Insulin; Receptors, Cell Surface; Substrate Specificity

1997
Chronic salt overload increases blood pressure and improves glucose metabolism without changing insulin sensitivity.
    American journal of hypertension, 1997, Volume: 10, Issue:7 Pt 1

    Topics: Adipocytes; Animals; Antimetabolites; Blood Pressure; Body Weight; Creatinine; Deoxyglucose; Epididymis; Glucose; Hypertrophy, Left Ventricular; In Vitro Techniques; Insulin Resistance; Lipid Metabolism; Male; Oxidation-Reduction; Rats; Rats, Wistar; Sodium Chloride, Dietary

1997
Differential effects of lipoic acid stereoisomers on glucose metabolism in insulin-resistant skeletal muscle.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 1

    Topics: Animals; Antioxidants; Biological Transport; Blood Glucose; Deoxyglucose; Fatty Acids, Nonesterified; Female; Glucose; Glycogen; Humans; Insulin; Insulin Resistance; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Reference Values; Stereoisomerism; Thioctic Acid

1997
Effect of glucocorticoid receptor antagonist RU 38486 on acute glucocorticoid-induced insulin resistance in rat adipocytes.
    Metabolism: clinical and experimental, 1997, Volume: 46, Issue:9

    Topics: Adipocytes; Animals; Biological Transport; Brain; Deoxyglucose; Dexamethasone; Glucocorticoids; Hormone Antagonists; Insulin; Insulin Resistance; Isoenzymes; Male; Mifepristone; Muscle Proteins; Muscle, Skeletal; Prednisolone; Protein Kinase C; Rats; Rats, Wistar; Receptors, Glucocorticoid; Time Factors

1997
A high-fat diet influences insulin-stimulated posttransport muscle glucose metabolism in rats.
    Metabolism: clinical and experimental, 1997, Volume: 46, Issue:9

    Topics: Animals; Biological Transport; Deoxyglucose; Dietary Fats; Epinephrine; Glucose; Glucose Clamp Technique; Hyperglycemia; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Rats; Rats, Wistar; Tissue Distribution

1997
Fatty acid-induced insulin resistance in adipocytes.
    Endocrinology, 1997, Volume: 138, Issue:10

    Topics: Adipocytes; Animals; Cells, Cultured; Deoxyglucose; Epidermal Growth Factor; Fatty Acids; Glucose Transporter Type 4; Glycogen; Insulin; Insulin Resistance; Male; Monosaccharide Transport Proteins; Muscle Proteins; Myristates; Palmitates; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Stearates

1997
GLUT4 heterozygous knockout mice develop muscle insulin resistance and diabetes.
    Nature medicine, 1997, Volume: 3, Issue:10

    Topics: Animals; Blood Glucose; Blood Pressure; Deoxyglucose; Diabetes Mellitus, Type 2; Glucose Transporter Type 4; Heterozygote; Insulin; Insulin Resistance; Insulin Secretion; Isoproterenol; Male; Mice; Mice, Knockout; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Myocardium; Time Factors

1997
Insulin resistance of muscle glucose transport in rats fed a high-fat diet: a reevaluation.
    Diabetes, 1997, Volume: 46, Issue:11

    Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Deoxyglucose; Dietary Fats; Glucose; Glucose Transporter Type 4; Hypoxia; In Vitro Techniques; Insulin; Insulin Resistance; Male; Monosaccharide Transport Proteins; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Organ Size; Physical Exertion; Rats; Rats, Wistar; Swimming; Ulnar Nerve

1997
DHEA protects against visceral obesity and muscle insulin resistance in rats fed a high-fat diet.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: Animals; Biological Transport; Body Weight; Dehydroepiandrosterone; Deoxyglucose; Dietary Fats; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Obesity; Organ Size; Rats; Rats, Wistar; Viscera

1997
Interaction between BTBR and C57BL/6J genomes produces an insulin resistance syndrome in (BTBR x C57BL/6J) F1 mice.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:11

    Topics: Adipose Tissue; Animals; Biological Transport, Active; Body Weight; Crosses, Genetic; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Female; Genotype; Glucose Tolerance Test; Glucose Transporter Type 4; Hyperlipidemias; Hypoxia; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Organ Size; Sex Characteristics

1997
Elevated D-glucose induces insulin insensitivity in human umbilical endothelial cells isolated from gestational diabetic pregnancies.
    The Journal of physiology, 1998, Jan-01, Volume: 506 ( Pt 1)

    Topics: Amino Acids; Antimetabolites; Arginine; Calcium; Citrulline; Cyclic GMP; Deoxyglucose; Endothelium, Vascular; Epoprostenol; Female; Glucose; Humans; Insulin Resistance; Membrane Potentials; Onium Compounds; Organophosphorus Compounds; Pregnancy; Pregnancy in Diabetics; Umbilical Veins

1998
Blood flow and glucose uptake in denervated, insulin-resistant muscles.
    The American journal of physiology, 1998, Volume: 274, Issue:2

    Topics: Animals; Deoxyglucose; Insulin; Insulin Resistance; Kinetics; Male; Muscle Denervation; Muscle, Skeletal; Rats; Rats, Sprague-Dawley

1998
Development of insulin resistance in the JCR:LA-cp rat: role of triacylglycerols and effects of MEDICA 16.
    Diabetes, 1998, Volume: 47, Issue:5

    Topics: Animals; Deoxyglucose; Hypertriglyceridemia; Hypolipidemic Agents; Insulin; Insulin Resistance; Metabolic Clearance Rate; Microscopy, Electron; Muscles; Obesity; Palmitic Acids; Rats; Rats, Inbred Strains; Syndrome; Tissue Distribution; Triglycerides

1998
Glucosamine-induced insulin resistance in 3T3-L1 adipocytes is caused by depletion of intracellular ATP.
    The Journal of biological chemistry, 1998, Aug-07, Volume: 273, Issue:32

    Topics: 3T3 Cells; Adenosine Triphosphate; Adipocytes; Animals; Cell Fractionation; Deoxyglucose; Glucosamine; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Inosine; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor Protein-Tyrosine Kinases; Receptor, Insulin; Sodium Azide

1998
Potentiated beta-cell response to non-glucose stimuli in insulin-resistant C57BL/6J mice.
    European journal of pharmacology, 1998, Jun-05, Volume: 350, Issue:2-3

    Topics: Animals; Antimetabolites; Blood Glucose; Body Weight; Carbachol; Deoxyglucose; Diet; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Peptide Fragments; Protein Precursors; Sincalide; Stimulation, Chemical

1998
Tissue-specific effects of in vivo adenosine receptor blockade on glucose uptake in Zucker rats.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1998, Volume: 12, Issue:13

    Topics: Adipose Tissue; Animals; Biological Transport, Active; Deoxyglucose; Glucose; Hyperinsulinism; Insulin Resistance; Liver; Muscle, Skeletal; Myocardium; Obesity; Organ Specificity; Purinergic P1 Receptor Antagonists; Rats; Rats, Zucker; Xanthines

1998
Actions of the novel oral antidiabetic agent HQL-975 in insulin-resistant non-insulin-dependent diabetes mellitus model animals.
    Diabetes research and clinical practice, 1998, Volume: 41, Issue:2

    Topics: Administration, Oral; Animals; Deoxyglucose; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Insulin Resistance; Liver; Male; Mice; Mice, Inbred Strains; Oxazoles; Phenylalanine; Rats; Rats, Inbred Strains; Rats, Wistar

1998
Prevention of dexamethasone-induced insulin resistance by metformin.
    Biochemical pharmacology, 1998, Nov-01, Volume: 56, Issue:9

    Topics: Animals; Deoxyglucose; Dexamethasone; Glucose Transporter Type 1; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin Resistance; Male; Metformin; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Muscles; RNA, Messenger

1998
Role of skeletal muscle in thiazolidinedione insulin sensitizer (PPARgamma agonist) action.
    Endocrinology, 1998, Volume: 139, Issue:12

    Topics: Animals; Deoxyglucose; Humans; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Resistance; Male; Mice; Muscle, Skeletal; Myocardium; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors

1998
Reduced adipocyte insulin sensitivity in Caucasian and Asian subjects with coronary heart disease.
    Diabetic medicine : a journal of the British Diabetic Association, 1998, Volume: 15, Issue:12

    Topics: Adipocytes; Adolescent; Adult; Aged; Asia; Asian People; Biological Transport; Blood Glucose; Cells, Cultured; Cholesterol; Coronary Artery Bypass; Coronary Disease; Deoxyglucose; Fatty Acids, Nonesterified; Female; Glucose; Heart Valve Diseases; Humans; Insulin; Insulin Resistance; Kinetics; Male; Middle Aged; Regression Analysis; Triglycerides; United Kingdom; White People

1998
Benfluorex improves muscle insulin responsiveness in middle-aged rats previously subjected to long-term high-fat feeding.
    Life sciences, 1999, Volume: 64, Issue:1

    Topics: Aging; Animals; Biological Transport; Blood Glucose; Blotting, Northern; Body Weight; Deoxyglucose; Dietary Fats; Energy Intake; Fenfluramine; Glucose Transporter Type 4; Hypolipidemic Agents; Insulin; Insulin Resistance; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Rats; Rats, Sprague-Dawley

1999
Reduced glycogen phosphorylase activity in denervated hindlimb muscles of rat is related to muscle atrophy and fibre type.
    Life sciences, 1999, Volume: 64, Issue:4

    Topics: Animals; Atrophy; Deoxyglucose; Hindlimb; Insulin; Insulin Resistance; Male; Muscle Denervation; Muscle Fibers, Skeletal; Muscle, Skeletal; Organ Size; Phosphorylases; Rats; Rats, Wistar; Sciatic Nerve; Time Factors

1999
Insulin-mediated pseudoacromegaly in a patient with severe insulin resistance: association of defective insulin-stimulated glucose transport with impaired phosphatidylinositol 3-kinase activity in fibroblasts.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 1999, Volume: 107, Issue:2

    Topics: Acromegaly; Biological Transport; Cell Membrane; Cells, Cultured; Deoxyglucose; Female; Fibroblasts; Glucose Transporter Type 1; GTP-Binding Proteins; Humans; Immunosorbent Techniques; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Middle Aged; Monosaccharide Transport Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; rab4 GTP-Binding Proteins

1999
Hyperlactatemia reduces muscle glucose uptake and GLUT-4 mRNA while increasing (E1alpha)PDH gene expression in rat.
    The American journal of physiology, 1999, Volume: 276, Issue:5

    Topics: Animals; Blood Glucose; Deoxyglucose; Gene Expression; Glucose; Glucose Clamp Technique; Glucose Transporter Type 4; Insulin; Insulin Resistance; Lactic Acid; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Pyruvate Dehydrogenase Complex; Rats; Rats, Zucker; RNA, Messenger; Tritium

1999
Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade.
    Diabetes, 1999, Volume: 48, Issue:6

    Topics: Animals; Deoxyglucose; Enzyme Activation; Fatty Acids, Nonesterified; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Isoenzymes; Magnetic Resonance Spectroscopy; Male; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C-theta; Rats; Rats, Sprague-Dawley; Signal Transduction; Tyrosine; Zinc Fingers

1999
The beta2-adrenergic modulator celiprolol reduces insulin resistance in obese Zucker rats.
    Life sciences, 1999, Volume: 64, Issue:22

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Biological Transport, Active; Blood Glucose; Celiprolol; Deoxyglucose; Female; Hypertension; Insulin; Insulin Resistance; Metoprolol; Muscle, Skeletal; Obesity; Rats; Rats, Zucker

1999
The effect of the new oral hypoglycemic agent A-4166 on glucose turnover in the high fat diet-induced and/or in the hereditary insulin resistance of rats.
    Archives of physiology and biochemistry, 1998, Volume: 106, Issue:4

    Topics: Animals; Body Weight; Cyclohexanes; Deoxyglucose; Dietary Fats; Glucose; Glucose Clamp Technique; Hypoglycemic Agents; Insulin Resistance; Male; Nateglinide; Phenylalanine; Phosphorylation; Rats; Rats, Wistar

1998
Tumor necrosis factor-alpha and ceramides in insulin resistance.
    Lipids, 1999, Volume: 34 Suppl

    Topics: 3T3 Cells; Adipocytes; Animals; Biological Transport; Ceramides; Deoxyglucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Kinetics; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Sphingosine; Tumor Necrosis Factor-alpha

1999
Cross-talk mechanisms in the development of insulin resistance of skeletal muscle cells palmitate rather than tumour necrosis factor inhibits insulin-dependent protein kinase B (PKB)/Akt stimulation and glucose uptake.
    European journal of biochemistry, 1999, Volume: 266, Issue:1

    Topics: Animals; Biological Transport, Active; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Type 2; Down-Regulation; Fatty Acids, Nonesterified; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Microsomes; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Myristic Acid; Obesity; Palmitic Acid; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Signal Transduction; Tumor Necrosis Factor-alpha

1999
Lack of effect of insulin on glucose utilization of the hypothalamus in normotensive and hypertensive rats.
    Neuroscience letters, 2000, Jan-07, Volume: 278, Issue:1-2

    Topics: Animals; Caudate Nucleus; Deoxyglucose; Glucose; Hyperinsulinism; Hypertension; Hypothalamus; Insulin; Insulin Resistance; Prefrontal Cortex; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superior Colliculi; Sympathetic Nervous System

2000
Glucosamine-induced insulin resistance in 3T3-L1 adipocytes.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 278, Issue:1

    Topics: 3T3 Cells; Adipocytes; Animals; Cell Membrane; Deoxyglucose; Dose-Response Relationship, Drug; Glucosamine; Glucose Transporter Type 4; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Ribosomal Protein S6 Kinases; Tyrosine

2000
Less of insulin desensitization in sympathetic nerve terminals from wistar rats with insulin resistance.
    Journal of the autonomic nervous system, 2000, Apr-12, Volume: 80, Issue:1-2

    Topics: Adipocytes; Adrenergic Fibers; Animals; Aorta; Blood Glucose; Carbon Radioisotopes; Deoxyglucose; Glyburide; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Norepinephrine; Presynaptic Terminals; Rats; Rats, Wistar

2000
Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/Protein kinase B activation.
    The Journal of biological chemistry, 2000, Jun-16, Volume: 275, Issue:24

    Topics: 3T3 Cells; Adipocytes; Animals; Biological Transport, Active; COS Cells; Deoxyglucose; Enzyme Activation; Glucose; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; src Homology Domains

2000
Phosphatase activity in rat adipocytes: effects of insulin and insulin resistance.
    Journal of cellular biochemistry, 2000, Volume: 77, Issue:3

    Topics: 5'-Nucleotidase; Adipocytes; Animals; Cell Fractionation; Cell Membrane; Deoxyglucose; Fatty Acids; Immunoblotting; Insulin; Insulin Resistance; Male; Palmitates; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Protein Phosphatase 1; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley

2000
The mechanism of insulin resistance caused by HIV protease inhibitor therapy.
    The Journal of biological chemistry, 2000, Jul-07, Volume: 275, Issue:27

    Topics: 3T3 Cells; Adipocytes; Animals; Biological Transport; Deoxyglucose; Fluorescent Antibody Technique; Glucose Transporter Type 1; Glucose Transporter Type 4; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Insulin Resistance; Mice; Microscopy, Fluorescence; Monosaccharide Transport Proteins; Muscle Proteins; Oocytes; Signal Transduction; Xenopus laevis

2000
Short-term effects of growth hormone on myocardial glucose uptake in healthy humans.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 278, Issue:6

    Topics: Adult; Blood Glucose; Deoxyglucose; Fluorine Radioisotopes; Glucose; Glucose Clamp Technique; Human Growth Hormone; Humans; Insulin; Insulin Resistance; Male; Myocardium

2000
The role of atypical and conventional PKC in dehydroepiandrosterone-induced glucose uptake and dexamethasone-induced insulin resistance.
    Biochemical and biophysical research communications, 2000, Oct-22, Volume: 277, Issue:2

    Topics: Adipocytes; Adjuvants, Immunologic; Androstadienes; Animals; Antimetabolites; Carbazoles; Cells, Cultured; Dehydroepiandrosterone; Deoxyglucose; Dexamethasone; Enzyme Activation; Enzyme Inhibitors; Genes, Dominant; Glucocorticoids; Glucose; Indoles; Insulin Antagonists; Insulin Resistance; Male; Myristic Acids; Phosphatidylinositol 3-Kinases; Precipitin Tests; Protein Kinase C; Rats; Time Factors; Transfection; Wortmannin

2000
Insulin continues to induce plasminogen activator inhibitor 1 gene expression in insulin-resistant mice and adipocytes.
    Molecular medicine (Cambridge, Mass.), 2000, Volume: 6, Issue:8

    Topics: Adipocytes; Animals; Biological Transport; Blood Glucose; Cardiovascular Diseases; Cell Line; Deoxyglucose; Diabetes Mellitus, Type 2; Hyperinsulinism; In Situ Hybridization; Insulin; Insulin Resistance; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Plasminogen Activator Inhibitor 1; RNA, Messenger; Signal Transduction; Up-Regulation

2000
Acute impairment of insulin-mediated capillary recruitment and glucose uptake in rat skeletal muscle in vivo by TNF-alpha.
    Diabetes, 2000, Volume: 49, Issue:11

    Topics: Animals; Blood Flow Velocity; Blood Glucose; Blood Pressure; Capillaries; Deoxyglucose; Femoral Artery; Femoral Vein; Glucose; Glucose Clamp Technique; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Vascular Resistance; Xanthines

2000
High-fat diet-induced muscle insulin resistance: relationship to visceral fat mass.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:6

    Topics: Adipose Tissue; Animals; Blood Glucose; Carbon Radioisotopes; Deoxyglucose; Dietary Fats; Energy Intake; Fish Oils; Insulin; Insulin Resistance; Leptin; Male; Mannitol; Muscle, Skeletal; Rats; Rats, Wistar; Triglycerides; Tritium; Viscera

2000
Interferon-gamma-induced regulation of peroxisome proliferator-activated receptor gamma and STATs in adipocytes.
    The Journal of biological chemistry, 2001, Mar-09, Volume: 276, Issue:10

    Topics: Adipocytes; Animals; Biological Transport; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Proteins; Cell Nucleus; Cells, Cultured; Cytosol; Dactinomycin; Deoxyglucose; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Enzymologic; Immunoblotting; Insulin; Insulin Resistance; Interferon-gamma; Ligands; Mice; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; STAT1 Transcription Factor; STAT3 Transcription Factor; Sterol Regulatory Element Binding Protein 1; Time Factors; Trans-Activators; Transcription Factors; Transcription, Genetic

2001
Possible interactions between angiotensin II and insulin: effects on glucose and lipid metabolism in vivo and in vitro.
    The Journal of endocrinology, 2000, Volume: 167, Issue:3

    Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Area Under Curve; Cell Line; Deoxyglucose; Dose-Response Relationship, Drug; Fructose; Glucose Tolerance Test; Imidazoles; Insulin; Insulin Antagonists; Insulin Resistance; Male; Muscles; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Triglycerides

2000
A model to explore the interaction between muscle insulin resistance and beta-cell dysfunction in the development of type 2 diabetes.
    Diabetes, 2000, Volume: 49, Issue:12

    Topics: Acute-Phase Reaction; Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Type 2; Fasting; Glucose; Glucose Tolerance Test; Glycogen; Injections, Intraperitoneal; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Lipid Metabolism; Mice; Mice, Knockout; Muscle, Skeletal; Receptor, Insulin; Reference Values

2000
Cd36 and molecular mechanisms of insulin resistance in the stroke-prone spontaneously hypertensive rat.
    Diabetes, 2000, Volume: 49, Issue:12

    Topics: Adipocytes; Animals; Biological Transport; Catecholamines; CD36 Antigens; Deoxyglucose; Fatty Acids; Gene Deletion; Genetic Predisposition to Disease; Glucose; Insulin; Insulin Resistance; Lipolysis; Male; Mutation; Rats; Rats, Inbred BN; Rats, Inbred SHR; Rats, Inbred WKY; Stroke

2000
Sex hormones induce insulin resistance in 3T3-L1 adipocytes by reducing cellular content of IRS proteins.
    Diabetologia, 2000, Volume: 43, Issue:11

    Topics: 3-O-Methylglucose; 3T3 Cells; Adipocytes; Animals; Biological Transport; Deoxyglucose; Estradiol; Estriol; Estrone; Glucose; Glucose Transporter Type 4; Gonadal Steroid Hormones; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt

2000
Correction of hyperglycemia and insulin sensitivity by T-1095, an inhibitor of renal Na+-glucose cotransporters, in streptozotocin-induced diabetic rats.
    Japanese journal of pharmacology, 2000, Volume: 84, Issue:3

    Topics: Animals; Carbonates; Deoxyglucose; Diabetes Mellitus, Experimental; Glucosides; Hyperglycemia; Hypoglycemic Agents; In Vitro Techniques; Insulin Resistance; Lactic Acid; Male; Monosaccharide Transport Proteins; Muscle, Skeletal; Rats

2000
Decreased in situ insulin receptor dephosphorylation in hyperglycemia-induced insulin resistance in rat adipocytes.
    Diabetes, 2001, Volume: 50, Issue:1

    Topics: Adipocytes; Animals; Deoxyglucose; Hyperglycemia; Immunoblotting; Insulin Resistance; Male; Phosphorylation; Phosphotyrosine; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Tyrosine

2001
Insulin resistance with enhanced insulin signaling in high-salt diet-fed rats.
    Diabetes, 2001, Volume: 50, Issue:3

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Deoxyglucose; Diet, Sodium-Restricted; Enzyme Activation; Glucose Clamp Technique; Glycogen Synthase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; In Vitro Techniques; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Liver; Male; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Signal Transduction; Thiazoles; Thiazolidinediones; Tyrosine

2001
Studies with apolipoprotein A-II transgenic mice indicate a role for HDLs in adiposity and insulin resistance.
    Diabetes, 2001, Volume: 50, Issue:3

    Topics: Adipose Tissue; Animals; Apolipoprotein A-II; Blood Glucose; Deoxyglucose; Fasting; Hydrolysis; Insulin Resistance; Lipoproteins, HDL; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Skeletal; Reference Values; Triglycerides

2001
Glucocorticoid-induced insulin resistance associates with activation of protein kinase C isoforms.
    Cellular signalling, 2001, Volume: 13, Issue:3

    Topics: Adipocytes; Animals; Biological Transport; Cell Membrane; Cell Separation; Cells, Cultured; Corticosterone; Cytosol; Deoxyglucose; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Glucocorticoids; Insulin; Insulin Antagonists; Insulin Resistance; Isoenzymes; Male; Precipitin Tests; Prednisolone; Protein Kinase C; Radionuclide Imaging; Rats; Rats, Wistar; Time Factors

2001
Sibutramine metabolites increase glucose transport by cultured rat muscle cells.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2001, Volume: 25, Issue:4

    Topics: Animals; Appetite Depressants; Area Under Curve; Biological Transport; Cells, Cultured; Chromones; Cyclobutanes; Cycloheximide; Cytochalasin B; Deoxyglucose; Enzyme Inhibitors; Glucose; Insulin; Insulin Resistance; Morpholines; Muscles; Protein Synthesis Inhibitors; Rats; Time Factors

2001
Vascular insulin/insulin-like growth factor-1 resistance in female obese Zucker rats.
    Metabolism: clinical and experimental, 2001, Volume: 50, Issue:5

    Topics: Animals; Aorta; Cholera Toxin; Deoxyglucose; Drug Resistance; Endothelium, Vascular; Female; GTP-Binding Proteins; Insulin Resistance; Insulin-Like Growth Factor I; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Obesity; Pertussis Toxin; Phenylephrine; Protein-Tyrosine Kinases; Rats; Rats, Zucker; Receptor, Insulin; Tritium; Virulence Factors, Bordetella

2001
Pioglitazone ameliorates tumor necrosis factor-alpha-induced insulin resistance by a mechanism independent of adipogenic activity of peroxisome proliferator--activated receptor-gamma.
    Diabetes, 2001, Volume: 50, Issue:5

    Topics: 3T3 Cells; Adipocytes; Animals; Cell Differentiation; Cell Line; Deoxyglucose; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Mice; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotyrosine; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Transforming Growth Factor alpha

2001
Insulin can enhance GLUT4 gene expression in 3T3-F442A cells and this effect is mimicked by vanadate but counteracted by cAMP and high glucose--potential implications for insulin resistance.
    Biochimica et biophysica acta, 2001, Feb-14, Volume: 1535, Issue:2

    Topics: 3T3 Cells; Adipocytes; Animals; Blotting, Western; Culture Media; Cyclic AMP; Deoxyglucose; Enzyme Inhibitors; Gene Expression Regulation; Glucose; Glucose Transporter Type 4; Insulin; Insulin Resistance; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Protein Tyrosine Phosphatases; RNA, Messenger; Vanadates

2001
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta).
    Science (New York, N.Y.), 2001, Jun-01, Volume: 292, Issue:5522

    Topics: Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Gene Targeting; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Homeostasis; Insulin; Insulin Resistance; Islets of Langerhans; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Skeletal; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction

2001
Prevention of skeletal muscle insulin resistance by dietary cod protein in high fat-fed rats.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 281, Issue:1

    Topics: Adipose Tissue; Amino Acids; Animals; Cells, Cultured; Deoxyglucose; Diet; Dietary Fats; Dietary Proteins; Fishes; Glucose; Glucose Clamp Technique; Insulin Resistance; Kinetics; Male; Muscle, Skeletal; Myocardium; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2001
A defect in glycogen synthesis characterizes insulin resistance in hypertensive patients with type 2 diabetes.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:6

    Topics: Albuminuria; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Fibroblasts; Glucose; Glucose Clamp Technique; Glycogen; Glycogen Synthase; Humans; Hypertension; Insulin; Insulin Resistance; Liver; Male; Middle Aged

2001
Anti-insulin receptor autoantibodies in a patient with type B insulin resistance and fasting hypoglycemia.
    Acta diabetologica, 2000, Volume: 37, Issue:4

    Topics: Animals; Autoantibodies; Biological Transport; Blood Glucose; CHO Cells; Cricetinae; Deoxyglucose; Fasting; Female; Humans; Hypoglycemia; Immunoglobulin G; Infusions, Intravenous; Insulin; Insulin Resistance; Middle Aged; Phosphorylation; Postprandial Period; Receptor, Insulin; Recombinant Proteins; Transfection

2000
Growth hormone induces cellular insulin resistance by uncoupling phosphatidylinositol 3-kinase and its downstream signals in 3T3-L1 adipocytes.
    Diabetes, 2001, Volume: 50, Issue:8

    Topics: 3T3 Cells; Adipocytes; Animals; Biological Transport; Cell Line; Cytosol; Deoxyglucose; Human Growth Hormone; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Insulin-Like Growth Factor I; Janus Kinase 2; Kinetics; MAP Kinase Signaling System; Mice; Microsomes; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Signal Transduction; Swine; Transfection

2001
Selective angiotensin II receptor antagonism reduces insulin resistance in obese Zucker rats.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:4

    Topics: Angiotensin Receptor Antagonists; Animals; Area Under Curve; Biological Transport; Biphenyl Compounds; Blood Glucose; Body Weight; Deoxyglucose; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; Glucose Transporter Type 4; Heart; Insulin; Insulin Resistance; Irbesartan; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Organ Size; Rats; Rats, Zucker; Tetrazoles

2001
Effects of losartan in combination with or without exercise on insulin resistance in Otsuka Long-Evans Tokushima Fatty rats.
    European journal of pharmacology, 2001, Nov-02, Volume: 430, Issue:2-3

    Topics: Adipocytes; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Blotting, Western; Body Weight; Deoxyglucose; Diabetes Mellitus, Type 2; Enzyme Activation; Glucose; Glucose Tolerance Test; Glucose Transporter Type 4; Heart Rate; Insulin; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Losartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Physical Conditioning, Animal; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred OLETF

2001
[Effects of chloroquine on insulin sensitivity in insulin-resistant rats].
    Zhonghua yi xue za zhi, 1999, Volume: 79, Issue:11

    Topics: Animals; Chloroquine; Deoxyglucose; Glucose Clamp Technique; Insulin; Insulin Resistance; Liver; Male; Muscle, Skeletal; Rats

1999
beta-3 adrenergic agonist restores skeletal muscle insulin responsiveness in Sprague-Dawley rats.
    Biochemical and biophysical research communications, 2001, Dec-21, Volume: 289, Issue:5

    Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Animals; Biological Transport, Active; Blood Glucose; Body Composition; Deoxyglucose; Dioxoles; Fatty Acids, Nonesterified; In Vitro Techniques; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Rats; Rats, Sprague-Dawley

2001
Candesartan inhibits carotid intimal thickening and ameliorates insulin resistance in balloon-injured diabetic rats.
    Hypertension (Dallas, Tex. : 1979), 2001, Dec-01, Volume: 38, Issue:6

    Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Carotid Artery, Common; Cells, Cultured; Deoxyglucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Insulin Resistance; Male; Muscle, Smooth, Vascular; Obesity; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Tetrazoles; Tunica Intima

2001
Does fluoxetine administration influence insulin resistance in 90% pancreatectomized rats?
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:1

    Topics: Animals; Deoxyglucose; Fluoxetine; Glucose; Glycogen; Insulin; Insulin Resistance; Liver; Male; Muscle, Skeletal; Pancreas; Pancreatectomy; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors

2002
Glucose uptake and insulin action in human adipose tissue--influence of BMI, anatomical depot and body fat distribution.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2002, Volume: 26, Issue:1

    Topics: Adipose Tissue; Adult; Basal Metabolism; Biological Transport; Body Composition; Body Mass Index; Case-Control Studies; Deoxyglucose; Female; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Omentum

2002
Exercise training improves muscle insulin resistance but not insulin receptor signaling in obese Zucker rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2002, Volume: 92, Issue:2

    Topics: Animals; Deoxyglucose; Glucose Transporter Type 4; Insulin Receptor Substrate Proteins; Insulin Resistance; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Physical Conditioning, Animal; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Zucker; Receptor, Insulin; Signal Transduction

2002
Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistance.
    Diabetes, 2002, Volume: 51, Issue:3

    Topics: Adipocytes; Adipose Tissue; Animals; Carbon Radioisotopes; Deoxyglucose; Esterification; Fatty Acids; Fatty Acids, Nonesterified; Gene Expression; Glycerol; Glycerophosphates; Heterozygote; Homozygote; Hypertrophy; Insulin Resistance; Leptin; Male; Mice; Mice, Transgenic; Obesity; Phosphoenolpyruvate Carboxykinase (GTP); RNA, Messenger; Tumor Necrosis Factor-alpha

2002
Glucose transport by osmotic shock and vanadate is impaired by glucosamine.
    Biochemical and biophysical research communications, 2002, Mar-29, Volume: 292, Issue:2

    Topics: Adipocytes; Animals; Biological Transport; Cell Line; Deoxyglucose; Glucosamine; Glucose; Insulin; Insulin Resistance; Kinetics; Mice; Osmotic Pressure; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Vanadates

2002
Investigation of potential bioisosteric replacements for the carboxyl groups of peptidomimetic inhibitors of protein tyrosine phosphatase 1B: identification of a tetrazole-containing inhibitor with cellular activity.
    Journal of medicinal chemistry, 2002, Apr-25, Volume: 45, Issue:9

    Topics: Binding, Competitive; Caco-2 Cells; Cell Membrane Permeability; Crystallography, X-Ray; Deoxyglucose; Enzyme Inhibitors; Humans; Insulin Resistance; Models, Molecular; Molecular Mimicry; Peptides; Phenoxyacetates; Propionates; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Structure-Activity Relationship; Tetrazoles

2002
[Ganglioside GM3-mediated modulation of insulin resistance in 3T3-L1 adipocytes].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 2002, Volume: 77, Issue:3

    Topics: 3T3 Cells; Adipocytes; Animals; Deoxyglucose; Flow Cytometry; G(M3) Ganglioside; Insulin Resistance; Mice; Polymerase Chain Reaction; Receptor, Insulin; Tumor Necrosis Factor-alpha

2002
Improvement of insulin sensitivity by chelation of intracellular Ca(2+) in high-fat-fed rats.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:7

    Topics: Adipocytes; Animals; Blood Flow Velocity; Calcium; Chelating Agents; Deoxyglucose; Dietary Fats; Dose-Response Relationship, Drug; Egtazic Acid; Femoral Artery; Glucose Clamp Technique; Insulin; Insulin Resistance; Intracellular Fluid; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow

2002
High-salt diet enhances insulin signaling and induces insulin resistance in Dahl salt-sensitive rats.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:1

    Topics: Adipose Tissue; Animals; Deoxyglucose; Enzyme Activation; Humans; In Vitro Techniques; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Liver; Male; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Potassium, Dietary; Rats; Rats, Inbred Dahl; Signal Transduction; Sodium Chloride, Dietary; Species Specificity; Tyrosine

2002
Effect of fasting and streptozotocin diabetes on insulin binding and action in the isolated mouse soleus muscle.
    The Journal of clinical investigation, 1979, Volume: 64, Issue:5

    Topics: Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Enzyme Activation; Fasting; Glucose; Glycogen; Glycogen Synthase; Glycolysis; Hindlimb; Insulin; Insulin Resistance; Mice; Muscle Proteins; Muscles; Receptor, Insulin; Streptozocin

1979
Insulin resistance due to a defect distal to the insulin receptor: demonstration in a patient with leprechaunism.
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:7

    Topics: Autoantibodies; Biological Transport; Blood Glucose; Deoxyglucose; Disorders of Sex Development; Female; Humans; Infant; Insulin; Insulin Resistance; Receptor, Insulin; Syndrome

1978
[Insulin resistance factors of the skeletal muscles in aurothioglucose induced obesity in mice].
    Journees annuelles de diabetologie de l'Hotel-Dieu, 1978

    Topics: Animals; Aurothioglucose; Deoxyglucose; Fasting; Insulin; Insulin Resistance; Mice; Muscles; Obesity; Oxidative Phosphorylation; Receptor, Insulin

1978
Mechanism of insulin resistance in adipocytes of rats fed a high-fat diet.
    Journal of lipid research, 1979, Volume: 20, Issue:1

    Topics: Adipose Tissue; Animals; Biological Transport, Active; Deoxyglucose; Dietary Fats; Glucose; In Vitro Techniques; Insulin; Insulin Resistance; Kinetics; Male; Organ Size; Rats; Receptor, Insulin

1979
Studies on the mechanism of insulin resistance after injury in the mouse.
    Diabetologia, 1978, Volume: 14, Issue:5

    Topics: Animals; Biological Transport; Burns; Cell Membrane; Deoxyglucose; Glucose; Glycogen; Glycolysis; Insulin Resistance; Liver; Male; Mice; Muscles; Receptor, Insulin

1978
Studies of insulin insensitivity in soleus muscles of obese mice.
    Metabolism: clinical and experimental, 1978, Volume: 27, Issue:12 Suppl 2

    Topics: Animals; Antibodies; Biological Transport, Active; Deoxyglucose; Drug Resistance; Insulin; Insulin Resistance; Kinetics; Male; Mice; Mice, Obese; Muscles; Obesity; Receptor, Insulin

1978
Insulin induced changes in insulin binding and insulin-sensitivity of adipocytes.
    Metabolism: clinical and experimental, 1978, Volume: 27, Issue:12 Suppl 2

    Topics: Adipose Tissue; Animals; Biological Transport, Active; Deoxyglucose; Glucose; Insulin; Insulin Resistance; Kinetics; Male; Rats; Receptor, Insulin

1978
Primary insulin antagonism of glucose transport in muscle from the older-obese rat.
    Metabolism: clinical and experimental, 1978, Volume: 27, Issue:12 Suppl 2

    Topics: Aging; Animals; Biological Transport, Active; Deoxyglucose; Diaphragm; Disease Models, Animal; Glucose; Glycogen; Glycolysis; Insulin; Insulin Resistance; Lactates; Lipid Metabolism; Male; Muscle Development; Obesity; Rats

1978
Mechanisms of decreased insulin responsiveness of large adipocytes.
    Endocrinology, 1977, Volume: 100, Issue:4

    Topics: Adipose Tissue; Animals; Deoxyglucose; Dogs; Fatty Acids; Glucose; Glycerides; In Vitro Techniques; Insulin; Insulin Resistance; Lipids; Male; Obesity; Oxidation-Reduction; Rats

1977
Cellular basis of insulin insensitivity in large rat adipocytes.
    The Journal of clinical investigation, 1976, Volume: 57, Issue:6

    Topics: Adipose Tissue; Animals; Biological Transport; Carbon Dioxide; Deoxyglucose; Fatty Acids; Glucose; Glycerides; Glycerol; Insulin; Insulin Resistance; Male; Methylglucosides; Rats

1976
Sepsis-induced insulin resistance in rats is mediated by a beta-adrenergic mechanism.
    The American journal of physiology, 1992, Volume: 263, Issue:4 Pt 1

    Topics: Animals; Atenolol; Deoxyglucose; Escherichia coli Infections; Glucose; Glucose Clamp Technique; Insulin Resistance; Male; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Tissue Distribution

1992
Postbinding characterization of five naturally occurring mutations in the human insulin receptor gene: impaired insulin-stimulated c-jun expression and thymidine incorporation despite normal receptor autophosphorylation.
    Biochemistry, 1992, Oct-20, Volume: 31, Issue:41

    Topics: Cell Line; Deoxyglucose; DNA; Fibroblasts; Gene Expression; Genes, jun; Humans; Insulin; Insulin Resistance; Kinetics; Mutation; Phosphorylation; Receptor, Insulin; Signal Transduction; Thymidine; Transfection

1992
The effects of testosterone on insulin sensitivity in male rats.
    Acta physiologica Scandinavica, 1992, Volume: 146, Issue:4

    Topics: Animals; Corticosterone; Deoxyglucose; Glucose; Glycogen; Insulin Resistance; Kinetics; Male; Muscles; Orchiectomy; Rats; Rats, Sprague-Dawley; Testis; Testosterone

1992
Contraction-activated glucose uptake is normal in insulin-resistant muscle of the obese Zucker rat.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 73, Issue:1

    Topics: Animals; Deoxyglucose; Electric Stimulation; Female; Glucose; Insulin Resistance; Isomerism; Monosaccharide Transport Proteins; Muscle Contraction; Muscles; Obesity; Rats; Rats, Zucker

1992
The contribution of hyperglycaemia and hypoinsulinaemia to the insulin resistance of streptozotocin-diabetic rats.
    Diabetologia, 1992, Volume: 35, Issue:4

    Topics: Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Eating; Fasting; Glucose; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Liver; Male; Organ Specificity; Rats; Rats, Zucker; Reference Values

1992
Muscle insulin resistance may not be a primary etiological factor in the genetically obese fa/fa rat.
    Endocrinology, 1992, Volume: 130, Issue:3

    Topics: Animals; Deoxyglucose; Diaphragm; Dose-Response Relationship, Drug; Gene Expression; Insulin; Insulin Resistance; Longitudinal Studies; Male; Monosaccharide Transport Proteins; Muscles; Obesity; Rats; Rats, Zucker; RNA, Messenger

1992
Role of glucose transporters in glucocorticoid-induced insulin resistance. GLUT4 isoform in rat skeletal muscle is not decreased by dexamethasone.
    Diabetes, 1992, Volume: 41, Issue:6

    Topics: 3-O-Methylglucose; Adipose Tissue; Animals; Blood Glucose; Cell Membrane; Deoxyglucose; Dexamethasone; DNA; Feeding Behavior; Insulin; Insulin Resistance; Male; Methylglucosides; Monosaccharide Transport Proteins; Muscles; Rats; Rats, Inbred Strains; RNA, Messenger

1992
The effects of cortisol on insulin sensitivity in muscle.
    Acta physiologica Scandinavica, 1992, Volume: 144, Issue:4

    Topics: Animals; Biological Transport, Active; Deoxyglucose; Female; Glycogen; Glycogen Synthase; Hydrocortisone; Insulin Resistance; Muscles; Rats; Rats, Inbred Strains

1992
Oral vanadate decreases muscle insulin resistance in obese fa/fa rats.
    Diabetologia, 1992, Volume: 35, Issue:6

    Topics: Administration, Oral; Animals; Blood Glucose; Deoxyglucose; Female; Glucose; Glucose Clamp Technique; Insulin; Insulin Resistance; Liver; Muscles; Obesity; Organ Specificity; Rats; Rats, Zucker; Reference Values; Vanadates

1992
Cytosolic calcium and insulin resistance in elderly patients with essential hypertension.
    American journal of hypertension, 1992, Volume: 5, Issue:7

    Topics: Adipose Tissue; Aged; Aging; Blood Glucose; Calcium; Cytosol; Deoxyglucose; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypertension; Insulin; Insulin Resistance; Nitrendipine; Obesity

1992
Induction of insulin resistance in primary cultured adult cardiac myocytes.
    Endocrinology, 1991, Volume: 129, Issue:1

    Topics: Animals; Biological Transport; Bucladesine; Cells, Cultured; Cyclic AMP; Cycloheximide; Cytochalasin B; Deoxyglucose; Fatty Acids; Heart; Insulin; Insulin Resistance; Isoproterenol; Male; Myocardium; Nifedipine; Phenylalanine; Phosphorylation; Rats; Rats, Inbred Strains

1991
Defects in insulin binding and receptor kinase in cells from a woman with type A insulin resistance and from her family.
    Diabetologia, 1991, Volume: 34, Issue:2

    Topics: Adolescent; Cells, Cultured; Deoxyglucose; Female; Fibroblasts; Glucose Clamp Technique; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Kinetics; Leukocytes, Mononuclear; Male; Protein-Tyrosine Kinases; Receptor, Insulin; Reference Values; Skin

1991
Mechanism of insulin resistance in CCl4-induced cirrhosis of rats.
    Gastroenterology, 1992, Volume: 102, Issue:1

    Topics: Adipose Tissue; Animals; Carbon Tetrachloride; Deoxyglucose; Epididymis; Glucose; Glucose Clamp Technique; Glycogen; Insulin; Insulin Resistance; Lipids; Lipolysis; Liver Cirrhosis, Experimental; Male; Rats; Rats, Inbred Strains

1992
Enhanced stimulation of diacylglycerol and lipid synthesis by insulin in denervated muscle. Altered protein kinase C activity and possible link to insulin resistance.
    Diabetes, 1991, Volume: 40, Issue:12

    Topics: Animals; Deoxyglucose; Diglycerides; In Vitro Techniques; Insulin; Insulin Resistance; Kinetics; Lipids; Male; Muscle Denervation; Muscles; Phospholipids; Protein Kinase C; Rats; Rats, Inbred Strains; Sciatic Nerve

1991
Insulin resistance in normal rats infused with glucose for 72 h.
    The American journal of physiology, 1991, Volume: 260, Issue:3 Pt 1

    Topics: Adipose Tissue; Animals; Blood Glucose; Cell Membrane; Deoxyglucose; Eating; Electrolytes; Energy Intake; Glucose; Glycogen Synthase; Hyperglycemia; Infusions, Intravenous; Insulin; Insulin Resistance; Male; Muscles; Rats; Rats, Inbred Strains; Receptor, Insulin; Reference Values; Sarcolemma

1991
Differential insulin sensitivity of 2-deoxyglucose transport into cardiac myocytes and adipocytes isolated from high-fat-fed rats.
    Biochemical Society transactions, 1990, Volume: 18, Issue:6

    Topics: Adipose Tissue; Animals; Biological Transport, Active; Deoxyglucose; Dietary Fats; In Vitro Techniques; Insulin Resistance; Male; Myocardium; Rats; Rats, Inbred Strains

1990
Insulinlike activity of new antidiabetic agent CP 68722 in 3T3-L1 adipocytes.
    Diabetes, 1990, Volume: 39, Issue:11

    Topics: Adipose Tissue; Animals; Benzopyrans; Biological Transport; Cell Line; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose; Insulin; Insulin Resistance; Oxidation-Reduction; Receptor, Insulin; Sulfonylurea Compounds; Temperature; Thiazoles; Thiazolidinediones

1990
Hyperinsulinemia increases the amount of GLUT4 mRNA in white adipose tissue and decreases that of muscles: a clue for increased fat depot and insulin resistance.
    Endocrinology, 1990, Volume: 127, Issue:6

    Topics: Adipose Tissue; Animals; Deoxyglucose; Glycolysis; Hyperinsulinism; Insulin; Insulin Resistance; Monosaccharide Transport Proteins; Muscles; Organ Specificity; Rats; Rats, Zucker; Reference Values; RNA, Messenger

1990
Mechanism of insulin resistance induced by sustained levels of cytosolic free calcium in rat adipocytes.
    Endocrinology, 1989, Volume: 125, Issue:5

    Topics: Adipose Tissue; Animals; Calcium; Cell Membrane; Cells, Cultured; Cytosol; Deoxy Sugars; Deoxyglucose; Insulin; Insulin Resistance; Ionomycin; Kinetics; Male; Monosaccharide Transport Proteins; Phosphorylation; Potassium; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Sphingosine

1989
Recovery of maximal insulin responsiveness and insulin sensitivity after induction of insulin resistance in primary cultured adipocytes.
    The Journal of biological chemistry, 1989, May-15, Volume: 264, Issue:14

    Topics: Adipose Tissue; Animals; Biological Transport; Cycloheximide; Deoxy Sugars; Deoxyglucose; Dose-Response Relationship, Drug; Glucose; Insulin; Insulin Resistance; Kinetics; Male; Protein Biosynthesis; Rats; Rats, Inbred Strains

1989
A potent in vivo effect of ciglitazone on muscle insulin resistance induced by high fat feeding of rats.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:11

    Topics: Animals; Blood Glucose; Deoxyglucose; Dietary Fats; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Muscles; Phosphorylation; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidinediones

1989
Changes in relationship between blood glucose level and plasma 1,5-anhydroglucitol level in KK mice.
    Biochemistry international, 1989, Volume: 18, Issue:3

    Topics: Animals; Blood Glucose; Deoxy Sugars; Deoxyglucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Insulin Resistance; Mice; Mice, Inbred Strains

1989
Fibroblasts from a leprechaun patient have defects in insulin binding and insulin receptor autophosphorylation.
    Diabetologia, 1988, Volume: 31, Issue:8

    Topics: Cells, Cultured; Deoxyglucose; Endocrine System Diseases; Fibroblasts; Humans; Infant, Newborn; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Male; Phosphorylation; Receptor, Insulin; Receptors, Cell Surface; Receptors, Somatomedin; Skin; Syndrome

1988
(Thr-59)-insulin-like growth factor I stimulates 2-deoxyglucose transport in BC3H1 myocytes through the insulin-like growth factor receptor, not the insulin receptor.
    Biochimica et biophysica acta, 1986, May-29, Volume: 886, Issue:3

    Topics: Animals; Biological Transport; Cell Line; Deoxy Sugars; Deoxyglucose; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Mice; Muscles; Receptor, Insulin; Receptors, Cell Surface; Receptors, Somatomedin; Somatomedins; Stimulation, Chemical

1986
Isoproterenol reduces insulin stimulation of hexose uptake by rat adipocytes via a postinsulin binding alteration.
    Endocrinology, 1986, Volume: 119, Issue:1

    Topics: Adipose Tissue; Animals; Biological Transport; Cyclic AMP; Deoxy Sugars; Deoxyglucose; Epididymis; Hydrogen-Ion Concentration; Insulin; Insulin Resistance; Isoproterenol; Lipolysis; Male; Phosphorylation; Rats; Rats, Inbred Strains; Receptor, Insulin

1986
Inhibition of insulin-stimulated glucose transport by factor extracted from serum of insulin-resistant patient.
    Diabetes, 1988, Volume: 37, Issue:9

    Topics: 3-O-Methylglucose; Acanthosis Nigricans; Adipose Tissue; Adult; Animals; Binding, Competitive; Deoxyglucose; Glucose; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Male; Methylglucosides; Muscles; Rats; Rats, Inbred Strains; Receptor, Insulin; Sorbitol; Vanadates

1988
Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats.
    Diabetes, 1988, Volume: 37, Issue:11

    Topics: Adipose Tissue; Animals; Benzopyrans; Blood Glucose; Chromans; Deoxyglucose; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Insulin Resistance; Ketone Bodies; Lactates; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Rats; Rats, Inbred Strains; Rats, Zucker; Receptor, Insulin; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone

1988
Effect of duration of diabetic state on insulin action in isolated rat soleus muscles.
    Metabolism: clinical and experimental, 1986, Volume: 35, Issue:6

    Topics: Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose; Glycogen; Glycogen Synthase; Insulin; Insulin Resistance; Male; Muscles; Rats; Rats, Inbred Strains; Receptor, Insulin

1986
Partial insulin resistance in the mouse BC3H-1 cell line: absent hexose-independent actions of insulin.
    Endocrinology, 1986, Volume: 119, Issue:1

    Topics: 3-O-Methylglucose; Animals; Cell Line; Concanavalin A; Deoxyglucose; Glucosephosphate Dehydrogenase; Glycogen; Glycogen Synthase; Glycogen-Synthase-D Phosphatase; Hexoses; Hydrogen Peroxide; Insulin; Insulin Resistance; Methylglucosides; Mice; Muscles; Neoplasms, Experimental; Vanadates; Vanadium

1986
Insulin response in individual tissues of control and gold thioglucose-obese mice in vivo with [1-14C]2-deoxyglucose.
    Diabetes, 1987, Volume: 36, Issue:2

    Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Aurothioglucose; Brain; Carbon Radioisotopes; Deoxy Sugars; Deoxyglucose; Dose-Response Relationship, Drug; Glucose; Gold; Insulin; Insulin Resistance; Male; Mice; Muscles; Myocardium; Obesity; Phosphorylation

1987
Possible role of cytosolic free calcium concentrations in mediating insulin resistance of obesity and hyperinsulinemia.
    The Journal of clinical investigation, 1988, Volume: 82, Issue:6

    Topics: Adipose Tissue; Adult; Biopsy; Calcium; Cytosol; Deoxyglucose; Female; Glyburide; Humans; Hyperinsulinism; In Vitro Techniques; Insulin; Insulin Resistance; Obesity; Verapamil

1988
Improper expression of insulin receptors on fibroblasts from a leprechaun patient.
    European journal of biochemistry, 1988, Mar-15, Volume: 172, Issue:3

    Topics: Cell Membrane; Cells, Cultured; Deoxyglucose; Dwarfism; Female; Fibroblasts; Gene Expression Regulation; Humans; Insulin; Insulin Resistance; Phosphorylation; Receptor, Insulin; RNA, Messenger

1988
Glucose and amino acid uptake by exercising muscles in vivo: effect of insulin, fiber population, and denervation.
    Endocrinology, 1987, Volume: 121, Issue:2

    Topics: Aminoisobutyric Acids; Animals; Body Water; Deoxy Sugars; Deoxyglucose; Insulin; Insulin Resistance; Male; Muscle Denervation; Muscles; Physical Exertion; Rats; Rats, Inbred Strains

1987
Intact adipocyte insulin-receptor phosphorylation and in vitro tyrosine kinase activity in animal models of insulin resistance.
    Diabetes, 1988, Volume: 37, Issue:2

    Topics: Adipose Tissue; Animals; Biological Transport; Cell Membrane; Deoxyglucose; Insulin Resistance; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin

1988
An in vitro human muscle preparation suitable for metabolic studies. Decreased insulin stimulation of glucose transport in muscle from morbidly obese and diabetic subjects.
    The Journal of clinical investigation, 1988, Volume: 82, Issue:2

    Topics: 3-O-Methylglucose; Adult; Biological Transport; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Tolerance Test; Humans; In Vitro Techniques; Insulin Resistance; Male; Methylglucosides; Muscles; Obesity, Morbid; Time Factors

1988
Functional characteristics of decreased insulin receptors on fibroblasts obtained from a subject with severe insulin resistance and acanthosis nigricans.
    Diabetes, 1986, Volume: 35, Issue:2

    Topics: Acanthosis Nigricans; Adolescent; Cells, Cultured; Chloroquine; Deoxyglucose; Dose-Response Relationship, Drug; Female; Fibroblasts; Humans; Insulin; Insulin Resistance; Monocytes; Receptor, Insulin

1986
Diabetes due to secretion of a structurally abnormal insulin (insulin Wakayama). Clinical and functional characteristics of [LeuA3] insulin.
    The Journal of clinical investigation, 1986, Volume: 77, Issue:2

    Topics: Adipose Tissue; Animals; Base Sequence; C-Peptide; Deoxyglucose; Diabetes Mellitus, Type 2; DNA; DNA, Recombinant; Female; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Middle Aged; Rats; Receptor, Insulin

1986
Insulin induces progressive insulin resistance in cultured rat adipocytes. Sequential effects at receptor and multiple postreceptor sites.
    Diabetes, 1986, Volume: 35, Issue:3

    Topics: 3-O-Methylglucose; Adipose Tissue; Animals; Cells, Cultured; Deoxyglucose; Dose-Response Relationship, Drug; Glucose; Humans; Insulin; Insulin Resistance; Male; Methylglucosides; Rats; Rats, Inbred Strains; Receptor, Insulin

1986
In vivo insulin resistance in individual peripheral tissues of the high fat fed rat: assessment by euglycaemic clamp plus deoxyglucose administration.
    Diabetologia, 1986, Volume: 29, Issue:3

    Topics: Adipose Tissue; Animals; Blood Glucose; Deoxyglucose; Dietary Fats; Glucose; Insulin; Insulin Resistance; Male; Muscles; Rats; Rats, Inbred Strains; Tritium

1986
2-Deoxyglucose tissue levels and insulin levels following tolazamide dosing in normal and obese mice.
    Experimental and clinical endocrinology, 1986, Volume: 87, Issue:3

    Topics: Adipose Tissue; Animals; Deoxy Sugars; Deoxyglucose; Insulin; Insulin Resistance; Male; Mice; Mice, Obese; Muscles; Obesity; Tissue Distribution; Tolazamide

1986
Glucose and insulin co-regulate the glucose transport system in primary cultured adipocytes. A new mechanism of insulin resistance.
    The Journal of biological chemistry, 1987, Jan-05, Volume: 262, Issue:1

    Topics: 3-O-Methylglucose; Adipose Tissue; Animals; Biological Transport; Cells, Cultured; Deoxyglucose; Drug Synergism; Glucose; Insulin; Insulin Resistance; Kinetics; Male; Methylglucosides; Rats; Rats, Inbred Strains

1987
Adipocyte insulin resistance: effects of aging, obesity, exercise, and food restriction.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 62, Issue:1

    Topics: Adipose Tissue; Aging; Animals; Deoxyglucose; Food Deprivation; Glucose; Insulin; Insulin Resistance; Obesity; Physical Exertion; Rats

1987
Decreased insulin responsiveness in fat cells rendered protein kinase C-deficient by a treatment with a phorbol ester.
    Endocrinology, 1987, Volume: 120, Issue:5

    Topics: Adipose Tissue; Animals; Biological Transport; Deoxyglucose; Insulin; Insulin Resistance; Lipids; Male; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

1987
Reevaluation of the evidence that an antibody to the insulin receptor is insulinmimetic without activating the protein tyrosine kinase activity of the receptor.
    The Journal of biological chemistry, 1987, Dec-15, Volume: 262, Issue:35

    Topics: Acanthosis Nigricans; Antibodies; Deoxyglucose; DNA; Humans; Insulin Resistance; Monosaccharide Transport Proteins; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Thymidine

1987
Glucose uptake and oxidation in fat cells of trained and sedentary pregnant rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 60, Issue:5

    Topics: Adipose Tissue; Animals; Biological Transport, Active; Deoxyglucose; Female; Glucose; Insulin Resistance; Oxidation-Reduction; Physical Conditioning, Animal; Physical Exertion; Pregnancy; Rats; Rats, Inbred Strains

1986
Evolution of insulin resistance in isolated soleus muscle of the NZO mouse.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1986, Volume: 18, Issue:5

    Topics: Animals; Biological Transport, Active; Deoxyglucose; Female; Glucose; Glycogen; Hyperglycemia; Hyperinsulinism; In Vitro Techniques; Insulin Resistance; Mice; Mice, Inbred BALB C; Mice, Obese; Muscles; Obesity

1986
Dynamics of insulin resistance in denervated slow and fast muscles in vivo.
    The American journal of physiology, 1987, Volume: 252, Issue:3 Pt 2

    Topics: Aminoisobutyric Acids; Animals; Denervation; Deoxyglucose; Insulin Resistance; Male; Muscle, Smooth; Muscles; Rats; Rats, Inbred Strains

1987
Autoantibodies against the insulin receptor. Dissociation of the acute effects of the antibodies from the desensitization seen with prolonged exposure.
    Diabetes, 1985, Volume: 34, Issue:3

    Topics: Animals; Autoantibodies; Cell Line; Cells, Cultured; Deoxyglucose; Desensitization, Immunologic; Humans; Insulin; Insulin Resistance; Mice; Rats; Receptor, Insulin; Temperature; Time Factors

1985
Low pH and ketoacids induce insulin receptor binding and postbinding alterations in cultured 3T3 adipocytes.
    Diabetes, 1985, Volume: 34, Issue:8

    Topics: Adipose Tissue; Animals; Cell Line; Clone Cells; Deoxyglucose; Diabetic Ketoacidosis; Hexoses; Hydrogen-Ion Concentration; Insulin Resistance; Keto Acids; Mice; Receptor, Insulin; Time Factors

1985
Effect of work-induced hypertrophy on muscle glucose metabolism in lean and obese mice.
    Diabetologia, 1985, Volume: 28, Issue:5

    Topics: Animals; Aurothioglucose; Body Weight; Deoxyglucose; Fructosediphosphates; Glycogen; Glycolysis; Hypertrophy; Insulin; Insulin Resistance; Male; Mice; Muscles; Obesity; Physical Exertion

1985