deoxyglucose has been researched along with Breast Neoplasms in 119 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (3.36) | 18.7374 |
1990's | 53 (44.54) | 18.2507 |
2000's | 14 (11.76) | 29.6817 |
2010's | 44 (36.97) | 24.3611 |
2020's | 4 (3.36) | 2.80 |
Authors | Studies |
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Bauerschmitz, G; Gallwas, J; Gründker, C; Steifensand, F | 1 |
Al-Shammari, AM; Khudair, KK; Obaid, QA | 1 |
Ge, XM; Li, JH; Liu, H; Liu, YM; Sun, XJ; Zhang, P; Zhen, YN | 1 |
Cho, YS; Jung, KH; Lee, JH; Lee, KH; Moon, SH; Park, JW | 1 |
Fujita, M; Imadome, K; Karasawa, K; Kawanishi, M; Somasundaram, V; Wink, DA | 1 |
Asghari Jafarabadi, M; Aval, NA; Hatamian, M; Mesbahi, A; Mohammadzadeh, M; Pirayesh Islamian, J; Rashidi, MR | 1 |
Bizjak, M; Dolinar, K; Malavašič, P; Pavlin, M; Pirkmajer, S; Pohar, J | 1 |
Islamian, JP; Jafarabadi, MA; Mahmoudian, B; Majidi Zolbanin, J; Maleki, LA; Shamsi, M; Zolbanin, NM | 1 |
Feng, X; He, M; Liu, Q; Mi, Z; Shi, Y; Wang, P; Wang, X; Xie, L; Zhang, K | 1 |
Berthe, A; Bost, F; De Fay, E; Flament, S; Foulquier, F; Houdou, M; Mazerbourg, S; Muller, C; Schulz, C; Zaffino, M | 1 |
Feng, X; Liu, Q; Shi, Y; Wang, P; Wang, X; Xie, L; Zhang, K | 1 |
Huang, G; Li, P; Liu, Q; Song, S; Wang, X | 1 |
Alvarez, JV; Crouch, BT; Fox, DB; Lee, J; Madonna, MC; Martinez, AF; Ramanujam, N; Zhu, C | 1 |
Deng, G; Jiang, K; Qiu, C; Shaukat, A; Wu, H; Zhang, T; Zhao, G; Zhu, X | 1 |
Huang, YY; Jiang, CC; Jiang, ZW; Li, Y; Liu, H; Pu, LJ; Xu, JC | 1 |
Alonso, A; Garrido, P; González, C; González, S; Morán, J | 1 |
Dewhirst, MW; Fontanella, AN; Frees, AE; Hansen, K; Rajaram, N; Ramanujam, N; Zhong, J | 1 |
Fan, Y; Gu, N; Qian, H; Shan, XH; Wang, P; Wang, YF; Xiong, F | 1 |
Chen, C; Cheng, Z; Gan, H; Jiang, C; Jiang, Z; Liu, H; Zhang, Q; Zhao, S | 1 |
Alacam, H; Bedir, A; Okuyucu, A; Ozdemir, T; Salis, O | 1 |
Barcaroli, D; Carollo, R; Ciavardelli, D; Consalvo, A; D'Agostino, D; D'Aguanno, S; De Cola, A; De Laurenzi, V; Di Ilio, C; Forlì, F; Rossi, C; Scavo, E; Stassi, G; Todaro, M; Urbani, A; Volpe, S; Zucchelli, M | 1 |
Feng, X; Liu, Q; Wang, P; Wang, X; Zhang, Y | 1 |
Dewhirst, MW; Fontanella, AN; Frees, AE; McCachren, SS; Rajaram, N; Ramanujam, N | 1 |
Fath, MA; Li, L; Scarbrough, PM; Spitz, DR; Watson, WH | 1 |
Hatamian, M; Islamian, JP; Rashidi, MR | 1 |
Abdalla, MY; Ahmad, IM; Al-Hudhud, MY; Elkarmi, AZ; Mahmoud, HT; Mustafa, EH; Tahtamouni, LH; Yasin, SR | 1 |
Lee, S; Mcghee, E; Sarkissyan, M; Vadgama, JV; Wu, Y | 1 |
Fan, Y; Gu, N; Hu, H; Lu, HY; Qian, W; Shan, XH; Wang, P; Xiong, F | 1 |
Baradaran, B; Farajollahi, A; Islamian, JP; Mohammadi, M; Monfared, AS; Oladghaffari, M; Shanehbandi, D | 1 |
Jia, R; Li, D; Ma, S; Shen, B | 1 |
Aghaee, F; Baradaran, B; Farajollahi, A; Fazel, M; Islamian, JP | 1 |
Dolinar, K; Miš, K; Pavlin, M; Pirkmajer, S; Rajh, M | 1 |
An, YS; Hur, H; Lee, SJ; Park, BN; Roh, JH; Yoon, JK | 1 |
Huo, X; Liu, K; Liu, Z; Ma, X; Meng, Q; Peng, J; Sun, H; Sun, P; Sun, Y; Wang, C; Xue, C | 1 |
Hu, H; Lu, HY; Shan, XH; Wang, P; Xiong, F | 1 |
Asghari Jafar Abadi, M; Baradaran, B; Farajollahi, A; Mohammadi, M; Oladghaffari, M; Pirayesh Islamian, J; Shabestani Monfared, A; Shanehbandi, D | 1 |
Foster, PA; Leese, MP; Newman, SP; Potter, BV; Purohit, A; Reed, MJ; Tagg, SL | 1 |
Ding, Y; Fodstad, O; Khong, HT; Liu, H; Tan, M; Yu, D; Zhao, YH; Zhou, M | 1 |
Baverel, G; Dubourg, L; Knouzy, B; Michoudet, C | 1 |
Aft, RL; Zhang, F | 1 |
Aykin-Burns, N; Coleman, MC; Hadzic, T; Jacobson, GM; Leick, K; Spitz, DR; Zhu, Y | 1 |
Ghahremani, MH; Ostad, SN; Seyedabadi, M | 1 |
Brown, JQ; Millon, SR; Ostrander, JH; Raheja, A; Ramanujam, N; Seewaldt, VL | 1 |
Kurtoglu, M; Lampidis, TJ; Liu, H; Liu, X; Savaraj, N; Wangpaichitr, M; Xi, H; You, M | 1 |
Emlet, DR; MacDonald, NJ; Papathanassiu, AE; Vu, HA | 1 |
Hu, H; Qian, H; Shan, XH; Wang, YF; Xu, WR; Zhu, W | 1 |
Geng, XD; Gu, N; Hu, H; Lin, J; Shan, XH; Wang, YF; Xiong, F; Zhu, W | 1 |
Chen, J; Ding, Y; Fodstad, O; Ledoux, SP; Lin, W; Lin, Y; Liu, B; Liu, H; Liu, Z; Nahta, R; Price, JE; Tan, M; Voellmy, R; Wilson, GL; Wu, Y; Zhao, Y | 1 |
Cheng, G; Dranka, BP; Joseph, J; Kalyanaraman, B; Mackinnon, AC; McAllister, D; Zielonka, J | 1 |
Chen, J; Kong, B; Roa, W; Song, K; Wilson, J; Xing, JZ; Xiong, Y; Yang, X | 1 |
Cai, H; Peng, F | 1 |
Edmonds, ME; González-Sarrías, A; Ma, H; Seeram, NP | 1 |
Aft, RL; Gius, D; Zhang, FW | 1 |
López-Rivas, A; Muñoz-Pinedo, C; Palacios, C; Ruiz de Almodóvar, C; Ruiz-Ruiz, C | 1 |
Keller, SH; Nigam, SK | 1 |
Astuya, A; Carvajal, A; García, MA; Guzman, C; Kato, S; Medina, RA; Meneses, AM; Nualart, F; Owen, GI; Pinto, M; Vera, JC | 1 |
Andringa, KK; Aykin-Burns, N; Coleman, MC; Domann, FE; Hitchler, MJ; Spitz, DR; Walsh, SA | 1 |
García, Mde L; Jaque, MP; Kato, S; Lizama, I; Medina, RA; Meneses, AM; Nualart, F; Owen, GI; Pinto, M | 1 |
Chen, Y; He, L; Huang, Z; Xiong, Q; Yang, X | 1 |
Jiang, W; Thompson, HJ; Zhu, Z | 1 |
Bronzert, TJ; Kidwell, WR; Lippman, ME; Monaco, ME; Osborne, CK | 1 |
Bonasera, TJ; Cutler, PD; Dehdashti, F; Detert, DD; Fusselman, MJ; Griffeth, LK; Katzenellenbogen, JA; Mortimer, JE; Siegel, BA; Welch, MJ | 1 |
Brown, RS; Ethier, SP; Fisher, SJ; Raylman, RR; Wahl, RL | 1 |
Pietrzyk, U; Scharl, A; Scheidhauer, K; Schicha, H; Schuster, A | 1 |
Ell, PJ | 1 |
Alavi, A; Buchpiguel, C; Chin, BB; Zukerberg, BW | 1 |
Ahlström, H; Bergh, J; Jansson, T; Långström, B; Lilja, A; Westlin, JE | 1 |
BenYounes, H; Bruce, DM; Eremin, O; Evans, NT; Heys, SD; Mikecz, P; Needham, G; Sharp, F; Smith, FW | 1 |
Adler, LP; Crowe, JP; Shenk, RR; Sunshine, J | 1 |
Cohen, JS; Kaplan, O | 1 |
Andersson, I; Chang, AE; Helvie, MA; Wahl, RL | 1 |
Cody, R; Helvie, M; Hutchins, GD; Wahl, RL; Weber, B; Zasadny, K | 1 |
Wahl, RL; Zasadny, KR | 1 |
Hortobagyi, GN; Kim, EE; Nieweg, OE; Singletary, SE; Wong, WH | 1 |
Glaspy, JA; Hawkins, R; Hoh, CK; Phelps, ME | 1 |
Dalbohm, NM; Glaspy, JA; Hawkins, RA; Hoh, CK; Moser, EA; Nitzsche, EU; Phelps, ME | 1 |
Broussard, WF; Hortobagyi, GN; Kim, EE; Nieweg, OE; Singletary, SE; Tilbury, RS; Wong, WH | 1 |
Choi, NC; Fischman, AJ; Hunter, GJ; McLoud, TC | 1 |
Chaiken, L; Choi, Y; Hawkins, R; Hoh, C; Jabour, B; Juillard, G; Parker, R; Rege, S | 1 |
Adler, LP; al-Kaisi, NK; Crowe, JP; Sunshine, JL | 1 |
Allgayer, B; Avril, N; Bense, S; Dose, J; Graeff, H; Herz, M; Jänicke, F; Laubenbacher, C; Nathrath, W; Pache, H; Römer, W; Schwaiger, M; Ziegler, S | 1 |
Göhring, UJ; Pietrzyk, U; Scharl, A; Scheidhauer, K; Schicha, H; Schomäcker, K; Wagner, R | 1 |
Aloj, L; Berg, W; Chang, V; Chow, C; Cowan, K; Danforth, D; Frank, J; Jones, E; Majewski, L; Majewski, S; Markowitz, A; Mulshine, J; Weinberg, I; Weisenberger, A; Zujewski, J | 1 |
Bassa, P; Buzdar, AU; Hicks, KW; Inoue, T; Kim, EE; Korkmaz, M; Podoloff, DA; Wong, FC; Wong, WH; Yang, DJ | 1 |
Holle, LH; Lung-Kurt, S; Oberhausen, E; Püschel, W; Schmidt, S; Trampert, L; Villena-Heinsen, CE | 1 |
Larcos, G; Maisey, MN | 1 |
Miyauchi, T; Wahl, RL | 1 |
Baselga, J; Concha, II; Delgado-López, F; Golde, DW; Nualart, F; Rivas, CI; Vera, JC; Zamora-León, SP | 1 |
Wagner, HN | 1 |
Avril, N; Dose, J; Graeff, H; Herz, M; Jänicke, F; Nathrath, W; Römer, W; Schwaiger, M; Weber, W; Ziegler, S | 1 |
Bassa, P; Hicks, K; Inoue, T; Kim, EE; Korkmaz, M; Podoloff, DA; Tansey, W; Wong, FC; Wong, WH; Yang, DJ | 1 |
Ficaro, EP; Raylman, RR; Wahl, RL | 1 |
Crane, PD; Leav, I; Nelson, CA; Wang, JQ | 1 |
Utech, CI; Winter, PF; Young, CS | 1 |
Krenning, EP; Kvols, LK; Van Eijck, CH | 1 |
Göhring, UJ; Pietrzyk, U; Scharl, A; Scheidhauer, K; Schomäcker, K | 1 |
Maublant, J | 1 |
Ben-Horin, H; Kaplan, O; Navon, G; Tassini, M; Vivi, A | 1 |
Adler, LP; Al-Kasi, NL; Faulhaber, PF; Schnur, KC; Shenk, RR | 1 |
Hoekstra, HJ; Kole, AC; Nieweg, OE; Paans, AM; Plukker, JT; Pruim, J; Schraffordt Koops, H; Vaalburg, W | 1 |
Ali, A; Alibazoglu, H; Fordham, E; LaMonica, G; Patel, PM | 1 |
Powe, JE | 1 |
Avril, N; Bense, S; Dose, J; Jänicke, F; Laubenbacher, C; Römer, W; Schwaiger, M; Weber, W; Ziegler, SI | 1 |
Bender, H; Biersack, HJ; Kozak, B; Oehr, P; Ruhlmann, J; Schräder, M; Willkomm, P | 1 |
Binder, C; Binder, L; Hiddemann, W; Kroemker, M; Schulz, M | 1 |
McCready, VR; Smith, TA; Titley, JC | 1 |
Diah, SK; Morrow, CS; Smitherman, PK; Townsend, AJ | 1 |
Bourque, CR; Collier, BD; Crane, PD; Edwards, SD; Hellman, RS; Kabasakal, L; Krasnow, AZ; Lindner, DJ; Liu, Y; Ozker, K | 1 |
Hejaz, HA; Potter, BV; Purohit, A; Reed, MJ; Singh, A | 1 |
Cailleux, N; Colombet-Lamau, C; de Beco, V; Grahek, D; Kerrou, K; Montravers, F; Petegnief, Y; Talbot, JN; Younsi, N | 1 |
Hakim, AA | 1 |
Altmann, A; Berger, MR; Dimitrakopoulou, A; Haberkorn, U; Oberdorfer, F; Reinhardt, M; Strauss, LG; van Kaick, G; Wallich, R | 1 |
Brunicardi, FC; Choi, Y; Dahlbom, M; Glaspy, JA; Hawkins, RA; Hoh, CK; Maddahi, J; Phelps, ME; Tse, NY; Zinner, MJ | 1 |
Cody, R; Hutchins, G; Mudgett, E; Wahl, RL | 1 |
Cody, RL; Hutchins, GD; Mudgett, EE; Wahl, RL | 1 |
Cohen, JS; Faustino, PJ; Kaplan, O; Lyon, RC; Navon, G; Straka, EJ | 1 |
Cohen, JS; Ennis, BW; Faustino, PJ; Jaroszewski, JW; Kaplan, O; Lippman, M; Zugmaier, G | 1 |
Cohen, JS; Kaplan, O; Lyon, RC; Navon, G | 1 |
Minn, H; Soini, I | 1 |
8 review(s) available for deoxyglucose and Breast Neoplasms
Article | Year |
---|---|
Nanoparticles promise new methods to boost oncology outcomes in breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Combined Modality Therapy; Contrast Media; Deoxyglucose; Doxorubicin; Drug Carriers; Female; Humans; Hyperthermia, Induced; Nanoparticles; Radiation-Sensitizing Agents | 2015 |
Thallium-201 uptake in lung cancer.
Topics: Breast Neoplasms; Carcinoma, Squamous Cell; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Heart; Humans; Indium Radioisotopes; Iodine Radioisotopes; Lung Neoplasms; Middle Aged; Octreotide; Sensitivity and Specificity; Technetium Tc 99m Sestamibi; Thallium Radioisotopes; Thoracic Neoplasms; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1995 |
Metabolism of breast cancer cells as revealed by non-invasive magnetic resonance spectroscopy studies.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Breast Neoplasms; Deoxyglucose; Drug Resistance, Multiple; Energy Metabolism; Growth Substances; Hormones; Humans; Magnetic Resonance Spectroscopy; Mice; Mice, Nude; Neoplasm Transplantation; Organoids; Specimen Handling; Tumor Cells, Cultured | 1994 |
Use of positron emission tomography in oncology.
Topics: Brain Neoplasms; Breast Neoplasms; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Neoplasms; Tomography, Emission-Computed | 1993 |
Nuclear medicine imaging of breast cancer.
Topics: Biopsy; Breast Neoplasms; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Indium Radioisotopes; Mammography; Octreotide; Reproducibility of Results; Technetium Tc 99m Sestamibi; Thallium Radioisotopes; Tomography, Emission-Computed | 1996 |
Scintigraphic imaging of breast tumors.
Topics: Breast Neoplasms; Clinical Trials as Topic; Deoxyglucose; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Technetium Tc 99m Sestamibi; Thallium Radioisotopes; Tomography, Emission-Computed | 1997 |
Positron emission tomography (PET) scanning in breast cancer.
Topics: Breast Neoplasms; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Neoplasm Staging; Tomography, Emission-Computed | 1997 |
[(18F)-fluoro-2-deoxyglucose PET in imaging of gynecologic cancers].
Topics: Breast Neoplasms; Deoxyglucose; Female; Fluorine Radioisotopes; Genital Neoplasms, Female; Humans; Lymphatic Metastasis; Neoplasm Recurrence, Local; Ovarian Neoplasms; Tomography, Emission-Computed; Uterine Cervical Neoplasms | 2001 |
2 trial(s) available for deoxyglucose and Breast Neoplasms
Article | Year |
---|---|
Positron emission tomography studies in patients with locally advanced and/or metastatic breast cancer: a method for early therapy evaluation?
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carbon Radioisotopes; Deoxyglucose; Female; Fluorodeoxyglucose F18; Humans; Liver Neoplasms; Lymphatic Metastasis; Methionine; Tomography, Emission-Computed | 1995 |
Preliminary results for positron emission mammography: real-time functional breast imaging in a conventional mammography gantry.
Topics: Breast; Breast Neoplasms; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Mammography; Middle Aged; Phantoms, Imaging; Time Factors; Tomography, Emission-Computed | 1996 |
109 other study(ies) available for deoxyglucose and Breast Neoplasms
Article | Year |
---|---|
Inhibition of Metabolism as a Therapeutic Option for Tamoxifen-Resistant Breast Cancer Cells.
Topics: Antimetabolites; Apoptosis; Benzeneacetamides; Breast Neoplasms; Cell Proliferation; Deoxyglucose; Drug Resistance, Neoplasm; Drug Therapy, Combination; Estrogen Antagonists; Female; Glutaminase; Glycolysis; Humans; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; Tamoxifen; Thiadiazoles; Tumor Cells, Cultured | 2021 |
Glucose deprivation using 2-deoxyglucose and acarbose induce metabolic oxidative stress and apoptosis in female mice bearing breast cancer.
Topics: Acarbose; Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Deoxyglucose; Female; Glucose; Glycolysis; Humans; Mice; Oxidative Stress | 2022 |
[Synergistic Effect of 2-deoxy-D-glucose Combined with Hydroxycamptothecin on Apoptosis of Breast Cancer Cells].
Topics: Apoptosis; Breast Neoplasms; Camptothecin; Cell Line, Tumor; Deoxyglucose; Drug Synergism; Humans; MCF-7 Cells | 2019 |
Troglitazone exerts metabolic and antitumor effects on T47D breast cancer cells by suppressing mitochondrial pyruvate availability.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxyglucose; Dose-Response Relationship, Drug; Female; Glycolysis; Humans; Mitochondria; Pyruvic Acid; Ribosomal Protein S6 Kinases, 70-kDa; Troglitazone | 2020 |
Metabolic characterization of aggressive breast cancer cells exhibiting invasive phenotype: impact of non-cytotoxic doses of 2-DG on diminishing invasiveness.
Topics: 4-Chloro-7-nitrobenzofurazan; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cellular Reprogramming; Citric Acid Cycle; Deoxyglucose; Female; Glucose; Glycolysis; Humans; Metabolome; Neoplasm Invasiveness | 2020 |
Targeted superparamagnetic nanoparticles coated with 2-deoxy-d-gloucose and doxorubicin more sensitize breast cancer cells to ionizing radiation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chemoradiotherapy; Combined Modality Therapy; Deoxyglucose; Doxorubicin; Female; Humans; Nanoparticles; Radiation Dosage; Radiation, Ionizing | 2017 |
Combined treatment with Metformin and 2-deoxy glucose induces detachment of viable MDA-MB-231 breast cancer cells in vitro.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Biphenyl Compounds; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxyglucose; Enzyme Activation; Female; Humans; Metformin; Pyrones; Ribonucleotides; Thiophenes | 2017 |
A study on drug delivery tracing with radiolabeled mesoporous hydroxyapatite nanoparticles conjugated with 2DG/DOX for breast tumor cells.
Topics: Animals; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Deoxyglucose; Doxorubicin; Drug Carriers; Durapatite; Humans; Isotope Labeling; Mice; Nanoparticles; Porosity; Technetium; Xenograft Model Antitumor Assays | 2018 |
Blocking the Glycolytic Pathway Sensitizes Breast Cancer to Sonodynamic Therapy.
Topics: Animals; Antimetabolites; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Deoxyglucose; Female; Glycolysis; Humans; Mice; Mice, Inbred BALB C; Ultrasonic Therapy | 2018 |
Protein N-glycosylation alteration and glycolysis inhibition both contribute to the antiproliferative action of 2-deoxyglucose in breast cancer cells.
Topics: Apoptosis; Breast Neoplasms; Cell Proliferation; Cell Survival; Deoxyglucose; Female; Glucose; Glycolysis; Glycoproteins; Glycosylation; Humans; MCF-7 Cells | 2018 |
2-deoxy-D-glucose augments photodynamic therapy induced mitochondrial caspase-independent apoptosis and energy-mediated autophagy.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Biomarkers; Blotting, Western; Breast Neoplasms; Caspases; Cell Line, Tumor; Deoxyglucose; Female; Humans; Mice; Mice, Inbred BALB C; Mitochondria; Photochemotherapy; Photosensitizing Agents; Random Allocation | 2019 |
18F-Deoxyglucose (18F-FDG) Positron Emission Tomography/Computed Tomography (PET/CT) Monitoring of Dynamic Growth Characteristics of Walker-256 Tumor Models in 3 Different Locations in Rats.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Disease Models, Animal; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Injections, Subcutaneous; Liver Neoplasms; Multimodal Imaging; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tomography, X-Ray Computed; Tumor Burden | 2019 |
Optical Imaging of Glucose Uptake and Mitochondrial Membrane Potential to Characterize Her2 Breast Tumor Metabolic Phenotypes.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Animals, Genetically Modified; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Female; Gene Expression Regulation, Neoplastic; Glucose; Humans; Mammary Glands, Animal; Membrane Potential, Mitochondrial; Neoplasm Recurrence, Local; Organometallic Compounds; Phenotype; Receptor, ErbB-2 | 2019 |
Targeting the ROS/PI3K/AKT/HIF-1α/HK2 axis of breast cancer cells: Combined administration of Polydatin and 2-Deoxy-d-glucose.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Enzymes; Female; Glucosides; Glycolysis; Hexokinase; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; MCF-7 Cells; Mice, Inbred BALB C; Molecular Structure; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Stilbenes; Xenograft Model Antitumor Assays | 2019 |
Down-regulation of RIP1 by 2-deoxy-D-glucose sensitizes breast cancer cells to TRAIL-induced apoptosis.
Topics: Apoptosis; Breast Neoplasms; Caspase 3; Caspase 8; Cell Line, Tumor; Deoxyglucose; Down-Regulation; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Humans; Nuclear Pore Complex Proteins; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA-Binding Proteins; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand | 2013 |
17β-estradiol activates glucose uptake via GLUT4 translocation and PI3K/Akt signaling pathway in MCF-7 cells.
Topics: 4-Chloro-7-nitrobenzofurazan; Blotting, Western; Breast Neoplasms; Cell Membrane; Deoxyglucose; Estradiol; Estrogen Receptor alpha; Estrogens; Female; Glucose; Glucose Transporter Type 4; Humans; MCF-7 Cells; Phosphatidylinositol 3-Kinase; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction | 2013 |
Delivery rate affects uptake of a fluorescent glucose analog in murine metastatic breast cancer.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Breast Neoplasms; Cell Line, Tumor; Deoxyglucose; Disease Models, Animal; Female; Fluorescent Dyes; Hypoxia; Kinetics; Mice; Neoplasm Metastasis; Oxygen Consumption; Regional Blood Flow; Sulfur Dioxide; Time Factors | 2013 |
[Comparison of the targeting properties of 2-deoxy-D-glucose-conjugated nanoparticles to breast cancer MDA-MB-231 cells and breast fibroblasts cells].
Topics: Breast Neoplasms; Cell Line, Tumor; Cells, Cultured; Colorimetry; Contrast Media; Deoxyglucose; Female; Ferric Compounds; Fibroblasts; Glucose; Humans; Iron; Magnetic Resonance Imaging; Nanoconjugates; Particle Size; Succimer | 2013 |
[2-Deoxy-D-glucose combined with Taxol inhibits VEGF expression and induces apoptosis in orthotopically transplanted breast cancer in C3H mice].
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Deoxyglucose; Drug Synergism; Female; Mice; Mice, Inbred C3H; Paclitaxel; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2014 |
The relationship between anticancer effect of metformin and the transcriptional regulation of certain genes (CHOP, CAV-1, HO-1, SGK-1 and Par-4) on MCF-7 cell line.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Breast Neoplasms; Caveolin 1; Deoxyglucose; Female; Heme Oxygenase-1; Humans; Immediate-Early Proteins; MCF-7 Cells; Metformin; Protein Serine-Threonine Kinases; RNA, Messenger; Transcription Factor CHOP | 2014 |
Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment.
Topics: Breast Neoplasms; Cell Line, Tumor; Deoxyglucose; Female; Glycolysis; Humans; L-Lactate Dehydrogenase; Neoplastic Stem Cells; Oxidative Phosphorylation; Pyruvate Kinase | 2014 |
Energy metabolism targeted drugs synergize with photodynamic therapy to potentiate breast cancer cell death.
Topics: Acetylcysteine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 3; Cell Line, Tumor; Cell Survival; Deoxyglucose; Female; Free Radical Scavengers; Human Umbilical Vein Endothelial Cells; Humans; MAP Kinase Kinase 4; Mitochondrial Membranes; p38 Mitogen-Activated Protein Kinases; Photochemotherapy; Photosensitizing Agents; Pyruvates; Reactive Oxygen Species | 2014 |
Delivery-corrected imaging of fluorescently-labeled glucose reveals distinct metabolic phenotypes in murine breast cancer.
Topics: 4-Chloro-7-nitrobenzofurazan; Adenocarcinoma; Animals; Blood Glucose; Breast Neoplasms; Cell Line, Tumor; Deoxyglucose; Female; Fluorescent Dyes; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Optical Imaging; Oxygen Consumption | 2014 |
Combined inhibition of glycolysis, the pentose cycle, and thioredoxin metabolism selectively increases cytotoxicity and oxidative stress in human breast and prostate cancer.
Topics: Antioxidants; Breast Neoplasms; Cell Line, Tumor; Dehydroepiandrosterone; Deoxyglucose; Drug Synergism; Female; Glycolysis; Humans; Male; Oxidative Stress; Pentose Phosphate Pathway; Prostatic Neoplasms; Thioredoxins | 2015 |
2-deoxy-D-Glucose Synergizes with Doxorubicin or L-Buthionine Sulfoximine to Reduce Adhesion and Migration of Breast Cancer Cells.
Topics: Actins; Antibiotics, Antineoplastic; Antimetabolites; Antioxidants; Apoptosis; Blotting, Western; Breast Neoplasms; Buthionine Sulfoximine; Cell Adhesion; Cell Movement; Cell Proliferation; Deoxyglucose; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Female; Flow Cytometry; Focal Adhesions; Glutathione; Humans; Lipid Peroxidation; Mitosis; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Tumor Cells, Cultured; Wound Healing | 2015 |
Combined inhibition of glycolysis and AMPK induces synergistic breast cancer cell killing.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Antineoplastic Agents; Breast Neoplasms; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclic AMP Response Element-Binding Protein; Deoxyglucose; Dose-Response Relationship, Drug; ERRalpha Estrogen-Related Receptor; Female; Glycolysis; Humans; Intracellular Space; MCF-7 Cells; Organelle Biogenesis; Phosphorylation; Protein Kinase Inhibitors; Receptors, Estrogen; RNA-Binding Proteins | 2015 |
MRI of High-Glucose Metabolism Tumors: a Study in Cells and Mice with 2-DG-Modified Superparamagnetic Iron Oxide Nanoparticles.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Deoxyglucose; Dextrans; Female; Frozen Sections; Glucose; Humans; Iron; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Staining and Labeling; Succimer | 2016 |
High Efficiency Apoptosis Induction in Breast Cancer Cell Lines by MLN4924/2DG Co-Treatment.
Topics: Antimetabolites; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Proliferation; Cyclopentanes; Deoxyglucose; Drug Therapy, Combination; Female; Humans; In Situ Nick-End Labeling; Pyrimidines; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Ubiquitin-Activating Enzymes | 2015 |
Targeting Cellular Metabolism Chemosensitizes the Doxorubicin-Resistant Human Breast Adenocarcinoma Cells.
Topics: Adenocarcinoma; AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Caspase 3; Cell Line, Tumor; Deoxyglucose; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; MCF-7 Cells; Multidrug Resistance-Associated Proteins; Tumor Suppressor Protein p53 | 2015 |
Combined Treatment with 2-Deoxy-D-Glucose and Doxorubicin Enhances the in Vitro Efficiency of Breast Cancer Radiotherapy.
Topics: Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Proliferation; Chemoradiotherapy; Deoxyglucose; Doxorubicin; Drug Synergism; Female; Humans; Radiation-Sensitizing Agents; Radiation, Ionizing; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2015 |
Medium Renewal Blocks Anti-Proliferative Effects of Metformin in Cultured MDA-MB-231 Breast Cancer Cells.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxyglucose; Female; Humans; Metformin; Signal Transduction | 2016 |
Enhancing the Therapeutic Efficacy of 2-Deoxyglucose in Breast Cancer Cells Using Cell-cycle Synchronization.
Topics: Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Deoxyglucose; Drug Synergism; Humans; Mibefradil | 2016 |
Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Breast Neoplasms; Cell Cycle Proteins; Deoxyglucose; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Energy Metabolism; Female; G2 Phase Cell Cycle Checkpoints; Humans; MCF-7 Cells; Metformin; Nuclear Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Signal Transduction; Tumor Suppressor Protein p53 | 2017 |
Detection of human breast cancer cells using a 2-deoxy-D-glucose-functionalized superparamagnetic iron oxide nanoparticles.
Topics: Breast Neoplasms; Cell Tracking; Deoxyglucose; Early Detection of Cancer; Female; Ferric Compounds; Fibroblasts; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; MCF-7 Cells; Succimer | 2017 |
MLN4924 and 2DG combined treatment enhances the efficiency of radiotherapy in breast cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Chemoradiotherapy; Cyclopentanes; Deoxyglucose; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; MCF-7 Cells; Pyrimidines; Radiotherapy Dosage; Treatment Outcome | 2017 |
2-Methoxyoestradiol-3,17-O,O-bis-sulphamate and 2-deoxy-D-glucose in combination: a potential treatment for breast and prostate cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Estrenes; Female; Humans; Immunohistochemistry; Male; Mice; Mice, Nude; Prostatic Neoplasms; Xenograft Model Antitumor Assays | 2008 |
Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth.
Topics: Animals; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; DNA-Binding Proteins; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glucose; Glycolysis; Heat Shock Transcription Factors; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Oxamic Acid; Oxygen; Receptor, ErbB-2; RNA, Small Interfering; Transcription Factors; Transcriptional Activation; Up-Regulation | 2009 |
Ifosfamide metabolite chloroacetaldehyde inhibits cell proliferation and glucose metabolism without decreasing cellular ATP content in human breast cancer cells MCF-7.
Topics: Acetaldehyde; Adenosine Triphosphate; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxyglucose; Female; Glucose; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Glycolysis; Hexokinase; Humans; Ifosfamide; Lactic Acid; Osmolar Concentration; Pyruvate Kinase | 2010 |
Chemosensitizing and cytotoxic effects of 2-deoxy-D-glucose on breast cancer cells.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cisplatin; Cyclophosphamide; Deoxyglucose; Doxorubicin; Drug Synergism; Female; Fluorouracil; Humans; Mice; Trastuzumab | 2009 |
Paclitaxel combined with inhibitors of glucose and hydroperoxide metabolism enhances breast cancer cell killing via H2O2-mediated oxidative stress.
Topics: Breast Neoplasms; Buthionine Sulfoximine; Cell Survival; Deoxyglucose; Drug Synergism; Female; Fibroblasts; Glucose; Humans; Hydrogen Peroxide; Oxidative Stress; Paclitaxel; Reactive Oxygen Species; Tumor Cells, Cultured | 2010 |
ATP depletion as a consequence of hypoxia enhances tamoxifen antiproliferative effects in T47D breast carcinoma cells.
Topics: Adenosine Triphosphate; Antimetabolites; Antineoplastic Agents, Hormonal; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Proliferation; Deoxyglucose; Female; Flow Cytometry; Humans; Hypoxia; Tamoxifen; Tumor Cells, Cultured | 2009 |
Uptake of 2-NBDG as a method to monitor therapy response in breast cancer cell lines.
Topics: 4-Chloro-7-nitrobenzofurazan; Antineoplastic Agents, Hormonal; Blotting, Western; Breast; Breast Neoplasms; Cells, Cultured; Deoxyglucose; Female; Glucose; Glucose Transporter Type 1; Hexokinase; Humans; Phosphorylation; Receptors, Estrogen; Tamoxifen; Treatment Outcome | 2011 |
2-Deoxy-D-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion.
Topics: Adenosine Triphosphate; Antimetabolites; Apoptosis; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Deoxyglucose; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Female; Fluorescent Antibody Technique; Humans; Melanoma; Pancreatic Neoplasms; Unfolded Protein Response | 2011 |
Antitumor activity of efrapeptins, alone or in combination with 2-deoxyglucose, in breast cancer in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Deoxyglucose; Down-Regulation; Female; HSP90 Heat-Shock Proteins; Humans; Inhibitory Concentration 50; Peptides | 2011 |
[Uptake of 2-NBDG by human breast cancer cells in vitro].
Topics: 4-Chloro-7-nitrobenzofurazan; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Deoxyglucose; Female; Flow Cytometry; Glucose Transporter Type 1; Humans; Immunohistochemistry; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Targeting Glut1-overexpressing MDA-MB-231 cells with 2-deoxy-D-g1ucose modified SPIOs.
Topics: Breast Neoplasms; Cell Line, Tumor; Contrast Media; Deoxyglucose; Dextrans; Glucose Transporter Type 1; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; Up-Regulation | 2012 |
Overcoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Deoxyglucose; DNA-Binding Proteins; Drug Resistance, Neoplasm; Drug Synergism; Female; Glucose; Glycolysis; Heat Shock Transcription Factors; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Organic Chemicals; Receptor, ErbB-2; Transcription Factors; Trastuzumab | 2011 |
Mitochondria-targeted drugs synergize with 2-deoxyglucose to trigger breast cancer cell death.
Topics: Animals; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Cyclic N-Oxides; Deoxyglucose; Drug Synergism; Female; Glycolysis; Humans; Mice; Mitochondria; Organophosphorus Compounds; Ubiquinone; Xenograft Model Antitumor Assays | 2012 |
Pharmacokinetic and toxicological evaluation of multi-functional thiol-6-fluoro-6-deoxy-D-glucose gold nanoparticles in vivo.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Cell Line, Tumor; Deoxyglucose; Female; Gold; Mice; Nanoparticles; Radiation-Sensitizing Agents; Sulfhydryl Compounds | 2012 |
2-NBDG fluorescence imaging of hypermetabolic circulating tumor cells in mouse xenograft model of breast cancer.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Deoxyglucose; Feasibility Studies; Female; Glucose; Humans; Mice; Molecular Imaging; Neoplastic Cells, Circulating; Spectrometry, Fluorescence | 2013 |
Maple polyphenols, ginnalins A-C, induce S- and G2/M-cell cycle arrest in colon and breast cancer cells mediated by decreasing cyclins A and D1 levels.
Topics: Acer; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Colonic Neoplasms; Cyclin A; Cyclin D; Deoxyglucose; Female; Gallic Acid; Gene Expression Regulation, Neoplastic; Humans; Male; Plant Extracts; Polyphenols; Sorbitol | 2013 |
Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: mechanism of cell death.
Topics: Antineoplastic Agents; Apoptosis; Biological Transport; Breast Neoplasms; Caspase 3; Caspases; Cell Division; Cell Survival; Deoxyglucose; Drug Design; Glucose; Glucose Transporter Type 1; Humans; Monosaccharide Transport Proteins; Poly(ADP-ribose) Polymerases; Time Factors; Tumor Cells, Cultured | 2002 |
Inhibition of glucose metabolism sensitizes tumor cells to death receptor-triggered apoptosis through enhancement of death-inducing signaling complex formation and apical procaspase-8 processing.
Topics: Adenosine Triphosphate; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Caspase 8; Caspase 9; Caspases; Cytochrome c Group; Deoxyglucose; Enzyme Activation; Enzyme Precursors; fas Receptor; Female; Glucose; HeLa Cells; Humans; Kinetics; Lymphoma; Membrane Glycoproteins; Mitochondria; Protein Processing, Post-Translational; Pyruvates; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; U937 Cells | 2003 |
Biochemical processing of E-cadherin under cellular stress.
Topics: Animals; Anti-Bacterial Agents; Antimycin A; beta Catenin; Breast Neoplasms; Cadherins; Caspase 3; Caspase Inhibitors; Caspases; Cell Fractionation; Cell Line; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytoskeletal Proteins; Deoxyglucose; Dogs; Enzyme Activation; Epithelial Cells; Female; Humans; In Situ Nick-End Labeling; Oligopeptides; Peptide Fragments; Trans-Activators | 2003 |
Estrogen and progesterone up-regulate glucose transporter expression in ZR-75-1 human breast cancer cells.
Topics: Breast Neoplasms; Deoxyglucose; Estradiol; Female; Humans; Monosaccharide Transport Proteins; Progesterone; Protein Isoforms; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation | 2003 |
Inhibition of glutamate cysteine ligase activity sensitizes human breast cancer cells to the toxicity of 2-deoxy-D-glucose.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Buthionine Sulfoximine; Cell Line, Tumor; Deoxyglucose; Drug Synergism; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Humans; Oxidative Stress; RNA, Messenger | 2006 |
Regulation of GLUT3 and glucose uptake by the cAMP signalling pathway in the breast cancer cell line ZR-75.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Cyclic AMP; Deoxyglucose; Dose-Response Relationship, Drug; Female; Fluorescent Antibody Technique, Indirect; Gene Expression Regulation, Neoplastic; Glucose; Glucose Transporter Type 3; Humans; Immunohistochemistry; Progesterone; RNA, Messenger; Signal Transduction | 2008 |
Preparation and imaging research on 188Re-DTPA-deoxyglucose in MCF-7 tumor-bearing mice.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Deoxyglucose; Female; Humans; Mice; Mice, Nude; Pentetic Acid; Radiography; Radioisotopes; Rhenium; Transplantation, Heterologous | 2007 |
Modulation of the activities of AMP-activated protein kinase, protein kinase B, and mammalian target of rapamycin by limiting energy availability with 2-deoxyglucose.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Breast Neoplasms; Cell Line, Tumor; Deoxyglucose; Female; Humans; Mammary Neoplasms, Animal; Models, Biological; Multienzyme Complexes; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases | 2008 |
Characterization of insulin regulation of lipid synthesis in MCF-7 human breast cancer cells.
Topics: Breast Neoplasms; Cell Line; Cells, Cultured; Deoxyglucose; Fatty Acids; Glucose; Humans; Insulin; Lipids; Phospholipids | 1983 |
Positron tomographic assessment of estrogen receptors in breast cancer: comparison with FDG-PET and in vitro receptor assays.
Topics: Breast; Breast Neoplasms; Deoxyglucose; Estradiol; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Middle Aged; Neoplasm Recurrence, Local; Radioligand Assay; Receptors, Estrogen; Tomography, Emission-Computed | 1995 |
Fluorine-18-fluorodeoxyglucose-guided breast cancer surgery with a positron-sensitive probe: validation in preclinical studies.
Topics: Animals; Beta Particles; Breast Neoplasms; Deoxyglucose; Equipment Design; Feasibility Studies; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Intraoperative Care; Mammary Neoplasms, Experimental; Phantoms, Imaging; Radioimmunodetection; Rats; Rats, Inbred Lew | 1995 |
Presurgical visualization of primary breast carcinoma with PET emission and transmission imaging.
Topics: Breast Neoplasms; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Image Processing, Computer-Assisted; Preoperative Care; Tomography, Emission-Computed | 1995 |
Keeping abreast of time.
Topics: Adult; Breast Neoplasms; Breast Self-Examination; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Indium Radioisotopes; Magnetic Resonance Imaging; Mammography; Middle Aged; Radioimmunodetection; Receptors, Somatostatin; Technetium Tc 99m Medronate; Technetium Tc 99m Sestamibi; Thallium Radioisotopes; Ultrasonography, Mammary | 1995 |
Positron emission tomography: 2-deoxy-2-[18F]-fluoro-D-glucose uptake in locally advanced breast cancers.
Topics: Adult; Aged; Breast Neoplasms; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Middle Aged; Predictive Value of Tests; Tomography, Emission-Computed | 1995 |
Positron emission tomography and breast masses: comparison with clinical, mammographic, and pathological findings.
Topics: Adult; Aged; Breast Neoplasms; Breast Neoplasms, Male; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lymphatic Metastasis; Male; Mammography; Middle Aged; Tomography, Emission-Computed | 1994 |
Detection of breast cancer in women after augmentation mammoplasty using fluorine-18-fluorodeoxyglucose-PET.
Topics: Adult; Breast Neoplasms; Deoxyglucose; Female; Fluorodeoxyglucose F18; Humans; Mammaplasty; Prostheses and Implants; Silicone Elastomers; Tomography, Emission-Computed | 1994 |
Metabolic monitoring of breast cancer chemohormonotherapy using positron emission tomography: initial evaluation.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Deoxyglucose; Feasibility Studies; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Mammography; Middle Aged; Tomography, Emission-Computed | 1993 |
Standardized uptake values of normal tissues at PET with 2-[fluorine-18]-fluoro-2-deoxy-D-glucose: variations with body weight and a method for correction.
Topics: Blood; Body Weight; Bone Marrow; Breast; Breast Neoplasms; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glucose; Humans; Liver; Lung; Middle Aged; Spleen; Tissue Distribution; Tomography, Emission-Computed | 1993 |
Positron emission tomography of glucose metabolism in breast cancer. Potential for tumor detection, staging, and evaluation of chemotherapy.
Topics: Adult; Breast Neoplasms; Carcinoma, Ductal, Breast; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glucose; Humans; Lymphatic Metastasis; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Tomography, Emission-Computed; Xeromammography | 1993 |
[Whole body positron emission tomography in breast cancer].
Topics: Adenocarcinoma; Adenofibroma; Adolescent; Adult; Aged; Breast Neoplasms; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Deoxyglucose; Female; Fluorodeoxyglucose F18; Humans; Middle Aged; Prospective Studies; Tomography, Emission-Computed | 1993 |
Positron emission tomography with fluorine-18-deoxyglucose in the detection and staging of breast cancer.
Topics: Adenocarcinoma; Adult; Breast; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lymph Nodes; Lymphatic Metastasis; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Sensitivity and Specificity; Tomography, Emission-Computed | 1993 |
Lung tumor metastasis to breast detected by fluorine-18-fluorodeoxyglucose PET.
Topics: Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Middle Aged; Tomography, Emission-Computed | 1993 |
Positron emission tomography with fluorodeoxyglucose to evaluate tumor response and control after radiation therapy.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Deoxyglucose; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy Dosage; Tomography, Emission-Computed | 1993 |
Evaluation of breast masses and axillary lymph nodes with [F-18] 2-deoxy-2-fluoro-D-glucose PET.
Topics: Adult; Aged; Aged, 80 and over; Axilla; Breast Neoplasms; Deoxyglucose; Female; Fluorodeoxyglucose F18; Humans; Lymph Nodes; Lymphatic Metastasis; Middle Aged; Sensitivity and Specificity; Tomography, Emission-Computed | 1993 |
Metabolic characterization of breast tumors with positron emission tomography using F-18 fluorodeoxyglucose.
Topics: Breast Neoplasms; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Middle Aged; Prospective Studies; ROC Curve; Sensitivity and Specificity; Tomography, Emission-Computed | 1996 |
Qualitative [18F]FDG positron emission tomography in primary breast cancer: clinical relevance and practicability.
Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lymphatic Metastasis; Mammography; Middle Aged; Neoplasm Staging; Time Factors; Tomography, Emission-Computed; Ultrasonography, Mammary | 1996 |
Evaluation of preoperative chemotherapy using PET with fluorine-18-fluorodeoxyglucose in breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Combined Modality Therapy; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lymphatic Metastasis; Mammography; Middle Aged; Neoplasm, Residual; Retrospective Studies; Sensitivity and Specificity; Tomography, Emission-Computed; Ultrasonography, Mammary | 1996 |
Investigations of breast tumors with fluorine-18-fluorodeoxyglucose and SPECT.
Topics: Breast Neoplasms; Deoxyglucose; Feasibility Studies; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Gamma Cameras; Humans; Lymphatic Metastasis; Middle Aged; Neoplasm Metastasis; Prospective Studies; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon | 1996 |
FDG-PET screening for cerebral metastases in patients with suspected malignancy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Breast Neoplasms; Child; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Lymphoma; Male; Melanoma; Middle Aged; Retrospective Studies; Sarcoma; Testicular Neoplasms; Tomography, Emission-Computed | 1996 |
Regional 2-[18F]fluoro-2-deoxy-D-glucose uptake varies in normal lung.
Topics: Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Case-Control Studies; Deoxyglucose; False Negative Reactions; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Image Processing, Computer-Assisted; Lung; Lung Neoplasms; Male; Middle Aged; Time Factors; Tomography, Emission-Computed | 1996 |
Expression of the fructose transporter GLUT5 in human breast cancer.
Topics: Breast; Breast Neoplasms; Deoxyglucose; Epithelium; Fructose; Glucose Transporter Type 1; Glucose Transporter Type 2; Glucose Transporter Type 5; Humans; Immunologic Techniques; Monosaccharide Transport Proteins; Tumor Cells, Cultured | 1996 |
1996 SNM annual meeting: medical problem solving.
Topics: Artifacts; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Colorectal Neoplasms; Contrast Media; Dementia; Deoxyglucose; Eye Neoplasms; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Genetic Therapy; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Melanoma; Neoplasms; Radioisotopes; Radiotherapy; Rhenium; Societies, Medical; Technetium; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1996 |
Assessment of axillary lymph node involvement in breast cancer patients with positron emission tomography using radiolabeled 2-(fluorine-18)-fluoro-2-deoxy-D-glucose.
Topics: Adult; Aged; Axilla; Breast Neoplasms; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lymphatic Metastasis; Middle Aged; Predictive Value of Tests; Sensitivity and Specificity; Tomography, Emission-Computed | 1996 |
Comparison of fluorine-18-fluorodeoxyglucose and carbon-11-methionine PET in detection of malignant tumors.
Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Methionine; Middle Aged; Neoplasm Recurrence, Local; Neoplasm, Residual; Sensitivity and Specificity; Soft Tissue Neoplasms; Tomography, Emission-Computed | 1996 |
Stereotactic coordinates from ECT sinograms for radionuclide-guided breast biopsy.
Topics: Biopsy, Needle; Breast Neoplasms; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Phantoms, Imaging; Software; Stereotaxic Techniques; Technetium Tc 99m Sestamibi; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1996 |
The interaction among glucose transport, hexokinase, and glucose-6-phosphatase with respect to 3H-2-deoxyglucose retention in murine tumor models.
Topics: Animals; Antimetabolites; Breast Neoplasms; Deoxyglucose; Female; Glucose-6-Phosphatase; Hexokinase; Humans; Lung Neoplasms; Mice; Mice, Nude; Monosaccharide Transport Proteins; Necrosis; Neoplasm Transplantation; Tissue Distribution; Transplantation, Heterologous; Tritium | 1996 |
Prospective evaluation of fluorine-18 fluorodeoxyclucose positron emission tomography in breast cancer for staging of the axilla related to surgery and immunocytochemistry.
Topics: Axilla; Breast Neoplasms; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Middle Aged; Neoplasm Staging; Prospective Studies; Sensitivity and Specificity; Tomography, Emission-Computed | 1996 |
[Detection of multi-focal breast carcinoma using 2[18F] fluoro-deoxy-D-glucose positron emission tomography (FDG-PET)].
Topics: Adult; Blood Glucose; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Deoxyglucose; Diagnosis, Differential; Female; Fibrocystic Breast Disease; Fluorodeoxyglucose F18; Glycolysis; Humans; Neoplasm Staging; Neoplasms, Second Primary; Tomography, Emission-Computed | 1996 |
Comparison of action of the anti-neoplastic drug lonidamine on drug-sensitive and drug-resistant human breast cancer cells: 31P and 13C nuclear magnetic resonance studies.
Topics: Antineoplastic Agents; Breast Neoplasms; Carbon Isotopes; Deoxyglucose; Drug Resistance, Neoplasm; Female; Humans; Indazoles; Magnetic Resonance Spectroscopy; Phosphorus Isotopes; Tumor Cells, Cultured | 1997 |
Axillary lymph node metastases: screening with [F-18]2-deoxy-2-fluoro-D-glucose (FDG) PET.
Topics: Adult; Aged; Axilla; Breast Neoplasms; Deoxyglucose; False Negative Reactions; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lymph Node Excision; Lymphatic Metastasis; Middle Aged; Neoplasm Staging; Predictive Value of Tests; Sensitivity and Specificity; Tomography, Emission-Computed | 1997 |
Standardized uptake value and quantification of metabolism for breast cancer imaging with FDG and L-[1-11C]tyrosine PET.
Topics: Blood Glucose; Breast; Breast Neoplasms; Carbon Radioisotopes; Carcinoma, Ductal, Breast; Deoxyglucose; Female; Fibrocystic Breast Disease; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Tomography, Emission-Computed; Tyrosine | 1997 |
'False-positive' uptake of FDG in a hepatic adenoma.
Topics: Adenoma; Adult; Breast Neoplasms; Deoxyglucose; False Positive Reactions; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Liver Neoplasms; Radiopharmaceuticals; Tomography, Emission-Computed | 1997 |
Breast imaging with fluorine-18-FDG PET: quantitative image analysis.
Topics: Breast Diseases; Breast Neoplasms; Deoxyglucose; Diagnosis, Differential; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Image Processing, Computer-Assisted; Middle Aged; Prospective Studies; Radiopharmaceuticals; Reproducibility of Results; ROC Curve; Tomography, Emission-Computed | 1997 |
[PET scan in general practice for diagnosis of breast carcinoma].
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Breast; Breast Neoplasms; Deoxyglucose; Female; Fluorodeoxyglucose F18; Follow-Up Studies; Humans; Lymphatic Metastasis; Middle Aged; Neoplasm Staging; Retrospective Studies; Sensitivity and Specificity; Tomography, Emission-Computed | 1997 |
Influence of cycloheximide-mediated downregulation of glucose transport on TNF alpha-induced apoptosis.
Topics: Adenosine Triphosphate; Apoptosis; Breast Neoplasms; Cycloheximide; Deoxyglucose; Down-Regulation; Drug Synergism; Gene Expression; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 3; Humans; Monosaccharide Transport Proteins; Nerve Tissue Proteins; Protein Synthesis Inhibitors; RNA, Messenger; Time Factors; Tritium; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Proliferation is associated with 2-deoxy-D-[1-3H]glucose uptake by T47D breast tumour and SW480 and SW620 colonic tumour cells.
Topics: Antimetabolites; Breast Neoplasms; Cell Count; Cell Cycle; Cell Division; Cell Line; Colonic Neoplasms; Deoxyglucose; Humans; Tumor Cells, Cultured | 1998 |
Detoxification of 1-chloro-2,4-dinitrobenzene in MCF7 breast cancer cells expressing glutathione S-transferase P1-1 and/or multidrug resistance protein 1.
Topics: Adenosine Triphosphate; ATP-Binding Cassette Transporters; Breast Neoplasms; Carrier Proteins; Cell Survival; Deoxyglucose; Dinitrochlorobenzene; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glutathione; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Inactivation, Metabolic; Inhibitory Concentration 50; Isoenzymes; Kinetics; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Oxidation-Reduction; Sodium Azide; Transfection; Tumor Cells, Cultured | 1999 |
Biodistribution of 99Tcm-labelled 5-thio-D-glucose.
Topics: Animals; Antimetabolites; Autoradiography; Breast Neoplasms; Deoxyglucose; Glucose; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Organotechnetium Compounds; Rabbits; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution; Transplantation, Heterologous | 1999 |
Inhibition of deoxyglucose uptake in MCF-7 breast cancer cells by 2-methoxyestrone and 2-methoxyestrone-3-O-sulfamate.
Topics: 2-Methoxyestradiol; Antineoplastic Agents; Biological Transport, Active; Breast Neoplasms; Deoxyglucose; Estradiol; Estrone; Female; Humans; Hydroxyestrones; Insulin; Kinetics; Paclitaxel; Tumor Cells, Cultured | 2000 |
Enzymatic modulation of the cell surface in malignant transformation of normal human mammary epithelial cells and in conversion of mammary carcinoma cells.
Topics: Breast; Breast Neoplasms; Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Concanavalin A; Deoxyglucose; Epithelial Cells; Female; Growth Substances; Humans; Neuraminidase; Trypsin | 1979 |
Metabolic design of combination therapy: use of enhanced fluorodeoxyglucose uptake caused by chemotherapy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chromatography, High Pressure Liquid; Deoxyglucose; Drug Screening Assays, Antitumor; Fluorodeoxyglucose F18; Humans; Phosphorylcholine; Tomography, Emission-Computed; Tumor Cells, Cultured | 1992 |
The application of positron emission tomographic imaging with fluorodeoxyglucose to the evaluation of breast disease.
Topics: Adolescent; Adult; Aged; Axilla; Breast Neoplasms; Deoxyglucose; Female; Fluorodeoxyglucose F18; Humans; Lymphatic Metastasis; Mammography; Middle Aged; Tomography, Emission-Computed | 1992 |
Positron-emission tomographic scanning of primary and metastatic breast carcinoma with the radiolabeled glucose analogue 2-deoxy-2-[18F]fluoro-D-glucose.
Topics: Breast Neoplasms; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Middle Aged; Neoplasm Metastasis; Tomography, Emission-Computed | 1991 |
Primary and metastatic breast carcinoma: initial clinical evaluation with PET with the radiolabeled glucose analogue 2-[F-18]-fluoro-2-deoxy-D-glucose.
Topics: Adult; Aged; Breast Neoplasms; Deoxyglucose; Feasibility Studies; Female; Fluorodeoxyglucose F18; Humans; Middle Aged; Tomography, Emission-Computed | 1991 |
Effects of 2-deoxyglucose on drug-sensitive and drug-resistant human breast cancer cells: toxicity and magnetic resonance spectroscopy studies of metabolism.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Deoxy Sugars; Deoxyglucose; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Drug Synergism; Glycolysis; Magnetic Resonance Spectroscopy; Phosphates; Phosphorylation; Tumor Cells, Cultured | 1990 |
Toxicity and effects of epidermal growth factor on glucose metabolism of MDA-468 human breast cancer cells.
Topics: Biological Transport, Active; Breast Neoplasms; Carbon Isotopes; Cell Division; Cell Line; Cell Survival; Deoxyglucose; Epidermal Growth Factor; Female; Glucose; Glycolysis; Humans; Kinetics; Phosphorylation; Tumor Cells, Cultured | 1990 |
Monitoring the transport and phosphorylation of 2-deoxy-D-glucose in tumor cells in vivo and in vitro by 13C nuclear magnetic resonance spectroscopy.
Topics: Animals; Biological Transport; Breast Neoplasms; Deoxy Sugars; Deoxyglucose; Glucose-6-Phosphate; Glucosephosphates; Humans; Kinetics; Magnetic Resonance Spectroscopy; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Phosphorylation; Tumor Cells, Cultured | 1989 |
[18F]fluorodeoxyglucose scintigraphy in diagnosis and follow up of treatment in advanced breast cancer.
Topics: Bone Neoplasms; Breast Neoplasms; Deoxy Sugars; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Follow-Up Studies; Humans; Middle Aged; Radionuclide Imaging | 1989 |