deoxyglucose has been researched along with Alloxan Diabetes in 162 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (26.54) | 18.7374 |
| 1990's | 58 (35.80) | 18.2507 |
| 2000's | 32 (19.75) | 29.6817 |
| 2010's | 25 (15.43) | 24.3611 |
| 2020's | 4 (2.47) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, X; Le, B; Qu, S | 1 |
| Abdel-Hamid, AZ; El-Maraghy, SA; Hanafy, MM; Lindeque, JZ; Shahin, NN | 1 |
| Benally, T; Chan, O; de Santana-Van Vliet, E; Farhat, R; Neely, L; Su, G | 1 |
| Adamski, J; Artati, A; Federici, M; Ghesquiere, B; Kappel, BA; Lehrke, M; Marx, N; Moellmann, J; Rau, M; Romeo, F; Schuett, K; Stoehr, R; Thiele, K | 1 |
| Albiston, AL; Burns, P; Cacador, M; Chai, SY; Sinnayah, P | 1 |
| Gao, M; Kudo, M; Li, L; Liu, T; Tsuru, R; Yoshitomi, H; Zhou, J | 1 |
| Kobayashi, S | 1 |
| Demarest, K; Du, F; Gaul, MD; Hinke, S; Huebert, ND; Kirchner, T; Kuo, GH; Lee, S; Liang, Y; Murray, W; Silva, J; Wallace, N; Xu, G; Xu, JZ | 1 |
| Fang, XS; Guo, JY; Jin, Z; Zhang, MH | 1 |
| Bertuzzi, A; Debard, C; Durand, C; Mingrone, G; Salinari, S; Vidal, H; Zimmet, P | 1 |
| Cao, Y; Chen, X; Himmeldirk, K; Kim, J; Li, Y; Liu, F; Liu, Y; Qian, Y; Ren, Y | 1 |
| Bao, Y; Bu, L; Gao, X; Liu, Z; Qu, S; Zou, J | 1 |
| Brouwers, O; de Vos-Houben, JM; Hageman, G; Janssen, BJ; Miyata, T; Niessen, PM; Schalkwijk, CG; Stehouwer, CD; van Nieuwenhoven, F | 1 |
| Liu, B; Shi, Y; Tang, L; Wang, J; Wang, Y; Wei, Q; Xu, H; Xu, W; Zhang, L; Zhao, G | 1 |
| Bo, P; Fang, P; Guo, L; Shi, M; Yu, M; Zhang, Z | 1 |
| Hardikar, MR; Joshi, BN; Kulkarni, AA; Kulkarni, PP; Varma, ME | 1 |
| Bergman, RN; Dorfman, MD; Kaiyala, KJ; Lantier, L; Matsen, ME; Mirzadeh, Z; Morton, GJ; Nguyen, HT; Rojas, JM; Scarlett, JM; Schwartz, MW; Stefanovski, D; Unterman, TG; Wasserman, DH | 1 |
| Chang, X; Cui, L; Liu, M; Sun, K | 1 |
| Davies, KP; Deng, GG; Wang, Y | 1 |
| Bu, L; Chang, X; Cheng, X; Qu, S; Sheng, C; Su, B; Yao, Q | 1 |
| Bhattacharya, S; Biswas, A; Dasgupta, S; Kundu, R; Pal, BC; Roy, SS | 1 |
| Iizuka, Y; Sakurai, E; Ueda, Y; Yagi, Y | 1 |
| Kong, T; Li, R; Li, Y; Liu, LY; Na, LX; Sun, CH; Zhang, YL | 1 |
| Ambrósio, AF; Carvalho, RA; Cristóvão, AJ; Duarte, JM; Garrido, MJ; Santiago, AR | 1 |
| Huang, ZB; Kong, H; Li, XJ; Niu, SN; Rao, XR; Sheng, GQ; Wang, H; Xu, J; Yang, C | 1 |
| Arai, M; Asami, J; Fukuhara, N; Gunji, E; Kitano, K; Kojima, N; Kozakai, A; Okumura-Kitajima, L; Takahashi, K; Takahashi, T; Tomoike, H; Toyoda, H; Uchida, S; Yamamoto, K | 1 |
| Alonso-Castro, AJ; Arana-Argáez, VE; Cabañas-Wuan, A; Carranza-Álvarez, C; Chávez, M; Domínguez, F; García-Carrancá, A; Ortiz-Andrade, R; Salazar-Olivo, LA; Zapata-Bustos, R | 1 |
| Cai, W; Chen, X; Ramdas, M; Striker, GE; Vlassara, H; Zhu, L | 1 |
| Adachi, I; Ishikawa, F; Kato, A; Kunimatsu, T; Takeshita, K; Yamashita, Y | 1 |
| Dohle, C; Gleichmann, H; im Walde, SS; Schott-Ohly, P | 1 |
| Lowy, C; Oon, BB; Thomas, CR | 1 |
| CORI, CF; KIPNIS, DM | 1 |
| AUGUSTIN, HW; HOFMANN, E; KALTEICH, WE; KUNZENDORF, HJ; LIESE, W; LUTZE, G; PRECHT, H; SEIRING, R | 1 |
| Kiso, Y; Nagai, K; Nakai, M; Niijima, A; Okumra, N; Otani, H; Tsuruoka, N; Yamano, T | 1 |
| Cefaratti, C; Romani, A | 1 |
| Cline, GW; Davies, PJ; Leibowitz, MD; Shen, Q; Shulman, GI | 1 |
| Abella, A; Carpéné, C; Marti, L; Palacín, M; Testar, X; Zorzano, A | 1 |
| Casson, RJ; Chidlow, G; Osborne, NN; Wood, JP | 1 |
| Bianchi, L; Colivicchi, MA; Della Corte, L; Pirisino, R; Raimondi, L; Tipton, KF | 1 |
| de Sousa, E; Horst, H; Jorge, AP; Pizzolatti, MG; Silva, FR | 1 |
| Aoyama, M; Endo, T; Ito, S; Kurano, Y; Uchida, Y | 1 |
| Boucher, J; Boutin, JA; Carpéné, C; Ferry, G; Grès, S; Guigné, C; Pradères, JP; Prévot, D; Quilliot, D; Saulnier-Blache, JS; Simon, MF; Valet, P | 1 |
| González, N; Malaisse, WJ; Sancho, V; Trigo, MV; Valverde, I; Villanueva-Peñacarrillo, ML | 1 |
| Cherng, JY; Shih, MF | 1 |
| Ambühl, P; Donath, MY; Dyntar, D; Klisic, J; Schaub, MC; Sergeev, P | 1 |
| Chan, CM; Chan, YW; Che, CT; Fung, KP; Ho, YY; Lam, FC; Lau, CB; Lau, CH; Lau, KM; Lau, TW; Leung, PC | 1 |
| Hirata, A; Igarashi, M; Kadomoto-Antsuki, Y; Nozaki, H; Tominaga, M | 1 |
| Nakagawa, T; Noguchi, H; Nonomura, T; Ono-Kishino, M; Sugaru, E; Taiji, M; Tsuchida, A; Yamanaka, M | 1 |
| Egawa, S; Gu, Y; Inoue, K; Matsuno, S; Qi, M; Sakata, N; Sumi, S; Sunamura, M; Unno, M; Yamamoto, C | 1 |
| Fukushima, M; Hattori, Y; Kajiwara, E; Kamata, K; Kawano, K; Kobayashi, T; Koga, K; Maitani, Y; Tsukada, H | 1 |
| Bagchi, D; Maulik, G; Maulik, N; Menon, VP; Penumathsa, SV; Thirunavukkarasu, M; Zhan, L | 1 |
| Cawthorne, MA; Levy, AL; Wilson, K; Young, P | 1 |
| García-Estañ, J; Miras Portugal, MT; Muñoz, A; Quesada, T; Serrano, C | 1 |
| Ladenheim, EE; Murnane, JM; Ritter, S | 1 |
| Ford, WC; Hamilton, DW | 1 |
| Bailey, A; Goldfine, ID; Humbel, R; Williams, JA | 1 |
| Tarui, S | 1 |
| Hyslop, PA; Kuhn, CE; Sauerheber, RD | 1 |
| Bikhazi, AB; Coe, EL; Nubani, HM | 1 |
| Iwasaki, M; Kobayashi, M; Maegawa, H; Ohgaku, S; Shigeta, Y; Watanabe, N | 1 |
| Bailey, AC; Goldfine, ID; Potau, N; Roach, E; Williams, JA | 1 |
| da Silva, RS; Machado, VL; Marques, M; Wassermann, GF | 1 |
| Vanderweele, DA | 1 |
| Coleman, DL; Garris, DR; Morgan, CR; Williams, SK | 1 |
| McCall, AL; Millington, WR; Wurtman, RJ | 1 |
| Bailey, AC; Goldfine, ID; Preissler, M; Williams, JA | 1 |
| Fellows, RE; Raizada, MK; Tan, G | 1 |
| Gross, R; Lakili, M; Laurent, F; Mialhe, P | 1 |
| Bloom, SR; Edwards, AV; Fielding, AS | 1 |
| Olefsky, JM; Saekow, M | 1 |
| Basnet, P; Kadota, S; Kobayashi, M; Namba, T; Shimizu, M; Takata, Y | 1 |
| Boileau, P; Girard, J; Hauguel-de Mouzon, S; Mrejen, C | 1 |
| Baynes, JW; Brown, TR; Kappler, F; Lal, S; Randall, WC; Szwergold, BS; Taylor, AH; Wells-Knecht, K | 1 |
| Assan, R; Burcelin, R; Eddouks, M; Girard, J; Kande, J; Maury, J | 1 |
| Dunbar, JC; Schultz-Klarr, S; Wright-Richey, J | 1 |
| Fujii, J; Lu, YB; Myint, T; Takahashi, M; Taniguchi, N; Wada, Y | 1 |
| Briggs, JP; Brosius, FC; Charron, MJ; England, R; Marcus, RG; Nguyen, K | 1 |
| Atkins, V; Flozak, AS; Ogata, ES; Simmons, RA | 1 |
| Igaki, N; Kasuga, M; Miyata, S; Miyauchi, Y; Ohara, T; Oimomi, M; Sakai, M; Shoda, H; Yamada, H; Yatabe, H | 1 |
| Benedict, M; Hingre, K; McCormick, KL; Mick, GJ | 1 |
| Joost, HG; Kainulainen, H; Schürmann, A; Vilja, P | 1 |
| Cartee, GD; Hacker, TA; Hall, JL; Smith, KR; Stanley, WC; Wisneski, JA | 1 |
| Aerts, L; Holemans, K; Van Assche, FA; Van Bree, R; Verhaeghe, J | 1 |
| Murakami, K; Uezu, Y | 1 |
| Girard, J; Leturque, A; Loizeau, M; Salminen, M; Vaulont, S | 1 |
| Salceda, R; Vilchis, C | 1 |
| Igarashi, H; Kwee, IL; Nakada, T | 1 |
| Katsuzaki, T; Miyazaki, T; Niwa, T; Takei, Y; Tatemichi, N | 1 |
| Böttcher, U; Eblenkamp, M; Fischer, Y; Jüngling, E; Kammermeier, H; Rösen, P; Thomas, J | 1 |
| Barnett, M; Cameron-Smith, D; Collier, GR; Habito, R | 1 |
| Comet, M; Grémeaux, T; Henry, C; Le Marchand-Brustel, Y; Morin, C; Tanti, JF; Van Obberghen, E | 1 |
| Kasuga, M; Liu, BF; Miyata, S; Ohara, T; Oimomi, M; Shoda, H; Suzuki, K; Yamada, H | 1 |
| Hayase, F; Ishizaki, Y; Katsuzaki, T; Miyazaki, T; Niwa, T; Takei, Y; Tatemichi, N; Uematsu, T | 1 |
| Bashan, N; Demshchak, E; Khamaisi, M; Potashnik, R; Rudich, A; Tirosh, A; Tritschler, H; Wessel, K | 1 |
| Flatt, PR; Gray, AM | 1 |
| Baydoun, R; Dunbar, JC | 1 |
| Brown, TR; Kappler, F; Lal, S; Randall, WC; Szwergold, BS; Taylor, AH; Walker, M | 1 |
| Attie, AD; Cartee, GD; Dumke, C; Ranheim, T; Schueler, KL | 1 |
| Araki, A | 1 |
| Feuvray, D; Lagadic-Gossmann, D; Le Prigent, K; Mongodin, E | 1 |
| Hanson, RW; Ismail-Beigi, F; Kalhan, SC; Leahy, P; Saker, F; Ybarra, J | 1 |
| Chi, MM; Moley, KH; Mueckler, MM | 1 |
| Eriksson, UJ; Minhas, HS; Thornalley, PJ; Wentzel, P | 1 |
| Hung, CR | 1 |
| Kurachi, H; Murata, Y; Ogura, K; Sakata, M; Yamaguchi, M | 1 |
| Krnjević, K; Tekkök, S | 1 |
| Arch, JR; Buckingham, RE; Cai, XJ; Clapham, JC; Harrold, J; Tadayyon, M; Widdowson, PS; Wilding, J; Williams, G; Wilson, S | 1 |
| Babsky, AM; Doliba, NM; Friedman, MF; Ivanics, TM; Osbakken, MD; Wehrli, SL | 1 |
| Ladriere, L; Malaisse, WJ; Malaisse-Lagae, F; Schoutens, A | 1 |
| Bailey, CJ; Bates, SH; Jones, RB | 1 |
| Ladrière, L; Malaisse, WJ; Sener, A | 2 |
| Ladrière, L; Malaisse, WJ; Malaisse-Lagae, F | 1 |
| Adachi, T; Arakawa, K; Ikezawa, K; Kano-Ishihara, T; Matsumoto, T; Oku, A; Saito, A; Tsuda, K; Ueta, K; Yasuda, K | 1 |
| Forga, L; Gómez-Ambrosi, J; Martínez, JA; Milagro, FI | 1 |
| Anai, M; Arakawa, K; Asano, T; Fujita, T; Funaki, M; Kano-Ishihara, T; Kikuchi, M; Nawano, M; Oka, Y; Oku, A; Saito, A; Ueta, K; Umebayashi, I | 1 |
| Setton-Avruj, CP; Speziale, EH; Sterin-Speziale, NB | 1 |
| Ahrén, B; Havel, PJ; Taborsky, GJ | 1 |
| Iwata, R; Kagaya, Y; Kaneta, T; Takahashi, S; Takai, Y; Tsujitani, M; Wada, H; Yamada, S; Yamane, Y; Yuki, M | 1 |
| Brown, T; Kappler, F; Schwartz, ML; Su, B; Tobia, AM | 1 |
| Foy, JM; Lucas, PD | 1 |
| Ganda, OP; Like, AA; Rossini, AA | 1 |
| Akanuma, Y; Iwamoto, Y; Kasuga, M; Kosaka, K | 1 |
| Freychet, P; Le Marchand-Brustel, Y | 1 |
| Fricke, RF; Longmore, WJ | 1 |
| Krans, HM; Wieringa, T | 1 |
| Kobayashi, M; Olefsky, JM | 2 |
| Panksepp, J | 1 |
| Kimura, I; Kimura, M; Kobayashi, S; Naitoh, T | 1 |
| Begum, N; Draznin, B | 1 |
| Akanuma, H; Morita, M | 1 |
| Lowy, C; Thomas, CR | 1 |
| Cusin, I; Del Prato, S; Jeanrenaud, B; Lisato, G; Tiengo, A | 1 |
| Jenkins, AB; Kusunoki, M; Pascoe, WS; Storlien, LH | 1 |
| Masui, H; Sakamoto, K; Wakabayashi, I; Yoshimoto, S | 1 |
| Arai, I; Hirose-Kijima, H; Muramatsu, M; Otomo, S; Usuki-Ito, C | 1 |
| Guerre-Millo, M; Kergoat, M; Lauva, M; Portha, B | 1 |
| Brown, LA | 1 |
| Chayoth, R; Field, CJ; Marliss, EB; Montambault, M | 1 |
| Farsky, SP; Fortes, ZB; Garcia-Leme, J; Oliveira, MA | 1 |
| Chan, TM; Shargill, NS; Zeidler, A | 1 |
| Farese, RV; Hoffman, JM; Ishizuka, T | 1 |
| Akaoka, I; Yamanouchi, T | 1 |
| Larkins, RG; Macaulay, SL | 1 |
| Migliorini, RH; Paschoalini, MA | 1 |
| Brown, TR; Kappler, F; Szwergold, BS | 1 |
| Aarslew-Jensen, M; Diemer, NH; Jakobsen, J; Nedergaard, M | 1 |
| Brøndsted, HE; Gjedde, A | 1 |
| Hayes, GR; Jacobs, DB; Lockwood, DH | 1 |
| Kawada, J; Nishida, M; Toide, K; Tsujihara, K; Yoshimura, Y | 1 |
| Akanuma, H; Akanuma, Y; Takaku, F; Yamanouchi, T | 1 |
| Fujiwara, T; Horikoshi, H; Ushiyama, I; Yoshioka, S; Yoshioka, T | 1 |
| Ishibashi, O; Kitamura, E; Kobayashi, M; Maegawa, H; Shigeta, Y; Takata, Y; Watanabe, N | 1 |
| Goto, Y; Ikeuchi, M; Inoue, T; Kaino, Y; Kida, K; Matsuda, H; Miyagawa, T | 1 |
| Diemer, NH; Jakobsen, J; Nedergaard, M | 1 |
| Abumrad, NA; Beth, AH; Briscoe, P; Whitesell, RR | 1 |
| Garris, DR; Michel, ME | 1 |
| Csaky, TZ | 1 |
| Akanuma, H; Akanuma, Y; Hashimoto, Y; Kametani, S; Yamanouchi, T | 1 |
| Papavassiliou, F; Ullrich, KJ | 1 |
| Krans, HM | 1 |
4 review(s) available for deoxyglucose and Alloxan Diabetes
| Article | Year |
|---|---|
[Pharmacological Mechanisms of Boiogito and Bofutsushosan in Diabetes and Obesity Models].
Topics: Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Drugs, Chinese Herbal; Gardenia; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Mice; Muscle, Skeletal; NF-kappa B; Obesity; Phytotherapy; Stephania; Streptozocin; Tumor Necrosis Factor-alpha | 2018 |
The alimentary canal, liver and vagus play a role in short-term feeding: but is the role regulation, correlation, glucostasis or spurious association?
Topics: Animals; Cholecystokinin; Deoxyglucose; Diabetes Mellitus, Experimental; Eating; Feeding Behavior; Glucagon; Insulin; Liver Glycogen; Rabbits; Rats; Tolbutamide; Vagus Nerve | 1984 |
[Oxidative stress and diabetes mellitus: a possible role of alpha-dicarbonyl compounds in free radical formation].
Topics: Animals; Cattle; Deoxyglucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Glycosylation; Humans; Ketoses; Oxidative Stress; Rats; Reactive Oxygen Species | 1997 |
Diabetes mellitus and insulin receptors.
Topics: Adipose Tissue; Animals; Biological Transport; Cell Membrane; Cell Nucleus; Coated Pits, Cell-Membrane; Deoxyglucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Erythrocytes; Glucose; Humans; Insulin; Lymphocytes; Receptor, Insulin | 1985 |
158 other study(ies) available for deoxyglucose and Alloxan Diabetes
| Article | Year |
|---|---|
Cooperative effects of galanin and leptin on alleviation of insulin resistance in adipose tissue of diabetic rats.
Topics: Adipocytes; Adiponectin; Adipose Tissue; Animals; Body Weight; Deoxyglucose; Diabetes Mellitus, Experimental; Feeding Behavior; Galanin; Glucose Clamp Technique; Glucose Transporter Type 4; Hyperinsulinism; Insulin Resistance; Leptin; Male; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Wistar; RNA, Messenger | 2020 |
Time-based investigation of urinary metabolic markers for Type 2 diabetes: Metabolomics approach for diabetes management.
Topics: Animals; Biomarkers; Carnitine; Cluster Analysis; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Progression; Fructose; Fucose; Galactose; Glycosuria; Inositol; Magnetic Resonance Spectroscopy; Male; Metabolome; Metabolomics; Phenylalanine; Rats; Rats, Wistar; Streptozocin; Taurine; Time Factors | 2021 |
Carvedilol prevents impairment of the counterregulatory response in recurrently hypoglycaemic diabetic rats.
Topics: Adrenergic beta-Antagonists; Animals; Awareness; Carvedilol; Deoxyglucose; Diabetes Mellitus, Experimental; Hypoglycemia; Male; Rats, Sprague-Dawley; Recurrence; Streptozocin | 2021 |
Human and mouse non-targeted metabolomics identify 1,5-anhydroglucitol as SGLT2-dependent glycemic marker.
Topics: Animals; Benzhydryl Compounds; Biomarkers; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Double-Blind Method; Glucosides; Humans; Metabolome; Mice; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Insulin-regulated aminopeptidase inhibitors do not alter glucose handling in normal and diabetic rats.
Topics: Animals; Biological Transport; Cell Differentiation; Cell Line; Cystinyl Aminopeptidase; Deoxyglucose; Diabetes Mellitus, Experimental; Gene Expression Regulation; Glucose; Glucose Transporter Type 4; Insulin; Male; Myoblasts; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin | 2017 |
Cyclocarya paliurus extract activates insulin signaling via Sirtuin1 in C2C12 myotubes and decreases blood glucose level in mice with impaired insulin secretion.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Biological Transport; Cell Line; Deoxyglucose; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Fagaceae; Gene Expression Regulation; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Male; Mice; Mice, Inbred ICR; Muscle Fibers, Skeletal; Muscle, Skeletal; Phosphatidylinositol 3-Kinase; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirtuin 1 | 2017 |
Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors.
Topics: Administration, Oral; Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Drug Design; Humans; Hypoglycemic Agents; Macaca fascicularis; Male; Mice; Microsomes, Liver; Molecular Structure; Rats, Sprague-Dawley; Rats, Zucker; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Structure-Activity Relationship | 2018 |
Effects of AMPK on Apoptosis and Energy Metabolism of Gastric Smooth Muscle Cells in Rats with Diabetic Gastroparesis.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Apoptosis; Blood Glucose; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Energy Metabolism; Gastroparesis; Glycolysis; Male; MAP Kinase Kinase Kinases; Mitochondria; Myocytes, Smooth Muscle; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley | 2019 |
Jejunal proteins secreted by db/db mice or insulin-resistant humans impair the insulin signaling and determine insulin resistance.
Topics: Adult; Animals; Cell Differentiation; Culture Media, Conditioned; Deoxyglucose; Diabetes Mellitus, Experimental; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Insulin; Insulin Resistance; Jejunum; Mice; Mice, Inbred C57BL; Muscle Fibers, Skeletal; Phosphorylation; Phosphoserine; Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction | 2013 |
Orally efficacious novel small molecule 6-chloro-6-deoxy-1,2,3,4-tetra-O-galloyl-α-D-glucopyranose selectively and potently stimulates insulin receptor and alleviates diabetes.
Topics: Adipocytes; Administration, Oral; Animals; Blood Glucose; Body Weight; Cell Line; Cell Proliferation; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Glucose; Glucose Intolerance; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Ligands; Male; Mice; Protein Binding; Receptor, Insulin; Signal Transduction; Time Factors | 2013 |
Blocking central galanin receptors attenuates insulin sensitivity in myocytes of diabetic trained rats.
Topics: Animals; Bradykinin; Cell Membrane; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Exercise Test; Galanin; Glucose Transporter Type 4; Insulin Resistance; Locomotion; Male; Muscle Cells; Peptide Fragments; PPAR alpha; Rats; Rats, Wistar; Receptors, Galanin; RNA, Messenger; Streptozocin; Tritium | 2013 |
Mild oxidative damage in the diabetic rat heart is attenuated by glyoxalase-1 overexpression.
Topics: Animals; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Experimental; Echocardiography; Fibrosis; Inflammation; Lactoylglutathione Lyase; Lysine; Myocardium; Oxidative Stress; Rats; Tandem Mass Spectrometry; Ventricular Remodeling | 2013 |
Discovery of 6-deoxydapagliflozin as a highly potent sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Discovery; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Molecular Structure; Rats; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Structure-Activity Relationship | 2014 |
Central alarin ameliorated insulin resistance of adipocytes in type 2 diabetic rats.
Topics: 4-Chloro-7-nitrobenzofurazan; Adipocytes; Adiponectin; Animals; Blood Glucose; Blotting, Western; Body Weight; Cell Membrane; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Galanin-Like Peptide; Gene Expression; Glucose Transporter Type 4; Injections, Intraventricular; Insulin Resistance; Male; Peptide Fragments; Protein Transport; Rats, Wistar; Retinol-Binding Proteins, Plasma; Reverse Transcriptase Polymerase Chain Reaction; Vesicle-Associated Membrane Protein 2 | 2014 |
Elucidation of hypoglycemic action and toxicity studies of insulin-like protein from Costus igneus.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Blood Glucose; Costus; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Mice; Muscle, Skeletal; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tumor Necrosis Factor-alpha | 2016 |
Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents.
Topics: Adipose Tissue; Animals; Blood Glucose; Blotting, Western; Body Composition; Brain; Carbon Radioisotopes; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Ependymoglial Cells; Fibroblast Growth Factor 1; Forkhead Box Protein O1; Glucose Tolerance Test; Heart; Heat-Shock Proteins; Hyperglycemia; Hypothalamus; Injections, Intraventricular; Liver; Male; Mice; Mice, Knockout; Mice, Obese; Molecular Chaperones; Muscle, Skeletal; Myocardium; Neoplasm Proteins; Proto-Oncogene Proteins c-fos; Rats; Rats, Zucker; Real-Time Polymerase Chain Reaction; Receptor, Insulin; Remission Induction | 2016 |
The inhibiting effect of the Coptis chinensis polysaccharide on the type II diabetic mice.
Topics: 3T3-L1 Cells; 4-Chloro-7-nitrobenzofurazan; Adenylate Kinase; Adipocytes; Adipokines; Animals; Blood Glucose; Body Weight; Coptis; Cytokines; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Fasting; Feeding Behavior; Gene Expression Regulation; Gluconeogenesis; Insulin; Lipids; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Polysaccharides | 2016 |
Novel insights into development of diabetic bladder disorder provided by metabolomic analysis of the rat nondiabetic and diabetic detrusor and urothelial layer.
Topics: Amino Acids, Branched-Chain; Animals; Bile Acids and Salts; Case-Control Studies; Citric Acid Cycle; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucose; Glycation End Products, Advanced; Glycolysis; Hydroxybutyrates; Lactic Acid; Lipid Metabolism; Male; Metabolomics; Muscle, Smooth; Oxidation-Reduction; Oxidative Stress; Pentose Phosphate Pathway; Polymers; Prostaglandins; Rats; Rats, Inbred F344; Sorbitol; Urinary Bladder; Urinary Bladder Diseases; Urothelium | 2016 |
Activated central galanin type 1 receptor alleviated insulin resistance in diabetic rat muscle.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Blood Glucose; Body Weight; Bradykinin; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Galanin; Glucose Tolerance Test; Glucose Transporter Type 4; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Peptide Fragments; PPAR gamma; Rats; Rats, Wistar; Receptor, Galanin, Type 1; Subcellular Fractions; Vesicle-Associated Membrane Protein 2 | 2016 |
Insulin resistance due to lipid-induced signaling defects could be prevented by mahanine.
Topics: Animals; Blood Glucose; Carbazoles; Cricetinae; Deoxyglucose; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Mesocricetus; Murraya; Muscle Fibers, Skeletal; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphorylation; Plant Leaves; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Rats; Receptor, Insulin; Signal Transduction | 2010 |
Significant improvement of insulin resistance of GK rats by treatment with sodium selenate.
Topics: Adipocytes; Animals; Biological Transport; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose Clamp Technique; Insulin; Insulin Resistance; Male; Rats; Rats, Wistar; Selenic Acid; Selenium Compounds | 2010 |
Curcumin improves insulin resistance in skeletal muscle of rats.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Biological Transport; Cell Line; Curcumin; Deoxyglucose; Diabetes Mellitus, Experimental; Dietary Fats; Dietary Supplements; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Male; Muscle, Skeletal; Palmitic Acid; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Random Allocation; Rats; Rats, Wistar; Signal Transduction | 2011 |
Evaluation of the impact of diabetes on retinal metabolites by NMR spectroscopy.
Topics: Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glucose; Glycolysis; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar; Retina | 2010 |
Brainstem Hap1-Ahi1 is involved in insulin-mediated feeding control.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Blood Glucose; Blotting, Western; Brain Stem; Cell Line, Tumor; Deoxyglucose; Diabetes Mellitus, Experimental; Eating; Fasting; Gene Expression Regulation; Hypoglycemic Agents; Immunohistochemistry; Insulin; Male; Mice; Mice, Inbred C57BL; Multiprotein Complexes; Nerve Tissue Proteins; Protein Binding; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Solitary Nucleus | 2011 |
TS-071 is a novel, potent and selective renal sodium-glucose cotransporter 2 (SGLT2) inhibitor with anti-hyperglycaemic activity.
Topics: Animals; Blood Glucose; CHO Cells; Cricetinae; Cricetulus; Deoxyglucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dogs; Glycosuria; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Kidney; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley; Rats, Zucker; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Sorbitol | 2011 |
Antidiabetic effects of Justicia spicigera Schltdl (Acanthaceae).
Topics: 3T3 Cells; 4-Chloro-7-nitrobenzofurazan; Acanthaceae; Adipocytes; Animals; Antioxidants; Benzothiazoles; Cell Survival; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Experimental; Ethanol; Glucose; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Kaempferols; Male; Mice; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Solvents; Sulfonic Acids | 2012 |
Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1.
Topics: 3T3-L1 Cells; Adipocytes; Administration, Oral; Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Humans; Inflammation; Insulin Receptor Substrate Proteins; Macrophages; Metabolic Syndrome; Mice; Oxidative Stress; Proto-Oncogene Proteins c-akt; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Sirtuin 1 | 2012 |
Protective effects of dietary 1,5-anhydro-D-glucitol as a blood glucose regulator in diabetes and metabolic syndrome.
Topics: Administration, Oral; alpha-Glucosidases; Animals; Blood Glucose; Cholesterol; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Glycoside Hydrolase Inhibitors; Glycosuria; Hyperglycemia; Intestines; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL | 2013 |
Molecular target structures in alloxan-induced diabetes in mice.
Topics: Alloxan; Animals; Antimetabolites; Binding Sites; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glucokinase; Glucose Tolerance Test; Glucose Transporter Type 2; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Monosaccharide Transport Proteins; Oxidation-Reduction; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Zinc | 2002 |
Placental transfer of lactate, glucose and 2-deoxyglucose in control and diabetic Wistar rats.
Topics: Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Female; Fetal Blood; Fetus; Glucose; Lactates; Maternal-Fetal Exchange; Perfusion; Placenta; Pregnancy; Pregnancy in Diabetics; Rats; Rats, Wistar; Reference Values; Regional Blood Flow | 2001 |
Studies of tissue permeability. VI. The penetration and phosphorylation of 2-deoxyglucose in the diaphram of diabetic rats.
Topics: Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose; Muscles; Permeability; Phosphorylation; Rats | 1960 |
[ON THE EFFECTS OF 2-DESOXY-D-GLUCOSE ON THE BLOOD GLUCOSE LEVEL AND GLYCOGEN CONTENT OF THE LIVER AND MUSCULATURE OF NORMAL AND ALLOXAN DIABETIC RATS].
Topics: Alloxan; Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose; Glycogen; Liver; Liver Glycogen; Muscles; Rats; Research | 1964 |
Possible role of L-carnosine in the regulation of blood glucose through controlling autonomic nerves.
Topics: Animals; Autonomic Pathways; Blood Glucose; Carnosine; Deoxyglucose; Diabetes Mellitus, Experimental; Dipeptidases; Diphenhydramine; Eating; Histamine; Histidine; Histidine Decarboxylase; Hyperglycemia; Male; Methylhistidines; Muscles; Photoperiod; Rats; Rats, Wistar | 2003 |
Intravesicular glucose modulates magnesium2+ transport in liver plasma membrane from streptozotocin-treated rats.
Topics: Adenosine Triphosphate; Amylopectin; Animals; Antimetabolites; Biological Transport, Active; Cell Membrane; Deoxyglucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Extracellular Space; Glucose; Glycogen; Hexoses; Liver; Magnesium; Male; Rats; Rats, Sprague-Dawley; Sodium | 2003 |
Effects of rexinoids on glucose transport and insulin-mediated signaling in skeletal muscles of diabetic (db/db) mice.
Topics: Acyl Coenzyme A; Animals; Anticholesteremic Agents; Biological Transport; Blotting, Western; Body Weight; Cattle; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose; Insulin; Insulin Resistance; Ligands; Ligases; Mice; Muscle, Skeletal; Muscles; Organic Chemicals; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-cbl; Receptor, Insulin; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transcription Factors; Triglycerides; Tyrosine; Ubiquitin-Protein Ligases | 2004 |
Stimulation of glucose transport by semicarbazide-sensitive amine oxidase activity in adipocytes from diabetic rats.
Topics: Adipocytes; Amine Oxidase (Copper-Containing); Animals; Benzylamines; Biological Transport; Deoxyglucose; Diabetes Mellitus, Experimental; Insulin; Male; Rats; Rats, Mutant Strains; Rats, Wistar; Vanadates | 2003 |
The effect of hyperglycemia on experimental retinal ischemia.
Topics: Animals; Blood Glucose; Cyclophilins; Deoxyglucose; Diabetes Mellitus, Experimental; Electroretinography; Glucose; Hyperglycemia; Isotonic Solutions; Lactic Acid; Male; Rats; Rats, Wistar; Reperfusion Injury; Retina; Retinal Diseases; Retinal Vessels; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thy-1 Antigens; Vitreous Body | 2004 |
Taurine prevents streptozotocin impairment of hormone-stimulated glucose uptake in rat adipocytes.
Topics: Adipocytes; Adrenergic Agonists; Adrenergic Antagonists; Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Insulin; Isoproterenol; Male; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Taurine | 2004 |
Insulinomimetic effects of kaempferitrin on glycaemia and on 14C-glucose uptake in rat soleus muscle.
Topics: Animals; Bauhinia; Blood Glucose; Carbon Radioisotopes; Deoxyglucose; Diabetes Mellitus, Experimental; Drug Interactions; Glycosuria; Insulin; Kaempferols; Leucine; Male; Muscle, Skeletal; Plant Leaves; Random Allocation; Rats; Rats, Wistar | 2004 |
Immunochemical detection of 3-deoxyglucosone in serum.
Topics: Animals; Biomarkers; Blood Chemical Analysis; Deoxyglucose; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Immunoenzyme Techniques; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Streptozocin | 2004 |
Potential involvement of adipocyte insulin resistance in obesity-associated up-regulation of adipocyte lysophospholipase D/autotaxin expression.
Topics: Adipocytes; Animals; Biological Transport; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Glucose-6-Phosphate Isomerase; Glycoproteins; Humans; Insulin Resistance; Lipectomy; Mice; Mice, Inbred C57BL; Multienzyme Complexes; Obesity; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases | 2005 |
Effects of glucagon-like peptide-1 and exendins on kinase activity, glucose transport and lipid metabolism in adipocytes from normal and type-2 diabetic rats.
Topics: Adipocytes; Animals; Biological Transport, Active; Deoxyglucose; Diabetes Mellitus, Experimental; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; In Vitro Techniques; Lipid Metabolism; Lipids; Lipolysis; Male; Peptide Fragments; Peptides; Protein Kinases; Protein Precursors; Rats; Rats, Wistar; Venoms | 2005 |
Improving glycogenesis in Streptozocin (STZ) diabetic mice after administration of green algae Chlorella.
Topics: Adipose Tissue; Animals; Blood Glucose; Chlorella; Deoxyglucose; Diabetes Mellitus, Experimental; Dietary Supplements; Fatty Acids, Nonesterified; Glucose; Hypoglycemic Agents; Liver; Male; Mice; Mice, Inbred ICR; Muscle, Skeletal; Streptozocin | 2006 |
High glucose alters cardiomyocyte contacts and inhibits myofibrillar formation.
Topics: Animals; Antioxidants; Apoptosis; Blotting, Western; Cell Communication; Cell Size; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Experimental; Female; Glucose; Heart Ventricles; Immunohistochemistry; Myocytes, Cardiac; Myofibrils; Organ Size; Oxidative Stress; Rats | 2006 |
Influence of an anti-diabetic foot ulcer formula and its component herbs on tissue and systemic glucose homeostasis.
Topics: 3T3 Cells; Adipocytes; Animals; Blood Glucose; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Foot; Female; Fibroblasts; Glucose; Glucose Tolerance Test; Homeostasis; Humans; Mice; Microvilli; Phytotherapy; Plants, Medicinal; Rabbits; Rats; Rats, Wistar | 2007 |
Role of angiotensin II type-1 and type-2 receptors on vascular smooth muscle cell growth and glucose metabolism in diabetic rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta; Blood Glucose; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Experimental; DNA Replication; Imidazoles; Male; Muscle, Smooth, Vascular; Nuclear Proteins; Obesity; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 2007 |
Brain-derived neurotrophic factor enhances glucose utilization in peripheral tissues of diabetic mice.
Topics: Adipose Tissue, Brown; Animals; Blood Glucose; Brain-Derived Neurotrophic Factor; Carbon Radioisotopes; Deoxyglucose; Diabetes Mellitus, Experimental; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Norepinephrine; Recombinant Proteins; Tissue Distribution | 2007 |
Hyperglycemia and diabetic renal change in a model of polyvinyl alcohol bioartificial pancreas transplantation.
Topics: Animals; Bioartificial Organs; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gels; Glomerular Mesangium; Hyperglycemia; Insulin; Islets of Langerhans; Kidney Function Tests; Linear Models; Male; Mice; Mice, Inbred C57BL; Pancreas Transplantation; Pancreas, Artificial; Polyvinyl Alcohol; Rats; Rats, Wistar; Severity of Illness Index; Time Factors; Tissue Culture Techniques; Tissue Engineering; Transplantation, Heterologous | 2007 |
Adiponectin gene therapy of streptozotocin-induced diabetic mice using hydrodynamic injection.
Topics: 4-Chloro-7-nitrobenzofurazan; Adiponectin; Animals; Cell Line, Tumor; Deoxyglucose; Diabetes Mellitus, Experimental; Gene Transfer Techniques; Genetic Therapy; Hepatocytes; Humans; Injections; Liver; Mice; Streptozocin | 2007 |
Resveratrol enhances GLUT-4 translocation to the caveolar lipid raft fractions through AMPK/Akt/eNOS signalling pathway in diabetic myocardium.
Topics: AMP-Activated Protein Kinases; Animals; Biological Transport, Active; Blood Glucose; Caveolae; Caveolin 1; Caveolin 3; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose Transporter Type 4; Immunohistochemistry; In Vitro Techniques; Male; Myocardium; Myocytes, Cardiac; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes | 2008 |
Reduced maximum capacity of glycolysis in brown adipose tissue of genetically obese, diabetic (db/db) mice and its restoration following treatment with a thermogenic beta-adrenoceptor agonist.
Topics: Adipose Tissue, Brown; Adrenergic beta-Agonists; Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Ethanolamines; Female; Glycolysis; Hexokinase; Ketoglutarate Dehydrogenase Complex; Liver; Mice; Mice, Inbred C57BL; Mice, Obese; Muscles; Obesity; Phosphofructokinase-1 | 1984 |
Effect of diabetic hyperglycemia and other sugars on plasma dopamine-beta-hydroxylase activity.
Topics: Animals; Cattle; Deoxyglucose; Dextrans; Diabetes Mellitus, Experimental; Dopamine beta-Hydroxylase; Half-Life; Hyperglycemia; Inulin; Male; Rats; Rats, Inbred Strains | 1984 |
Glucoprivic feeding is impaired by lateral or fourth ventricular alloxan injection.
Topics: Alloxan; Angiotensin II; Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Drinking; Eating; Injections, Intraventricular; Insulin Antagonists; Male; Rats; Rats, Inbred Strains; Streptozocin | 1982 |
The effect of experimentally induced diabetes on the metabolism of glucose by seminiferous tubules and epididymal spermatozoa from the rat.
Topics: Alloxan; Animals; Blood Glucose; Body Weight; Deoxyglucose; Diabetes Mellitus, Experimental; Epididymis; Fructose; Glucose; Inositol; Male; Pyruvates; Rats; Rats, Inbred Strains; Seminiferous Tubules; Spermatozoa; Streptozocin; Testis | 1984 |
Insulinlike growth factors bind to specific receptors in isolated pancreatic acini.
Topics: Animals; Biological Transport, Active; Deoxyglucose; Diabetes Mellitus, Experimental; Insulin; Kinetics; Mice; Pancreas; Peptides; Receptors, Cell Surface; Receptors, Somatomedin; Somatomedins | 1984 |
[Forskolin, cyclic AMP and hormone regulation].
Topics: Adrenal Glands; Animals; Cell Membrane Permeability; Colforsin; Corticosterone; Cyclic AMP; Deoxyglucose; Diabetes Mellitus, Experimental; Diterpenes; Glucagon; In Vitro Techniques; Liver; Phosphofructokinase-1; Phosphotransferases; Rats | 1983 |
Membrane structural/functional properties of adipocytes from normal and streptozotocin-diabetic rats.
Topics: Adipose Tissue; Animals; Cell Membrane; Deoxyglucose; Diabetes Mellitus, Experimental; Electron Spin Resonance Spectroscopy; Glucose; Insulin; Insulin Resistance; Male; Rats; Rats, Inbred Strains; Temperature | 1984 |
Effect of insulin and dinoprostone on D-glucose and 2-deoxy-D-glucose uptake by normal and diabetic rat hepatocytes.
Topics: Animals; Deoxy Sugars; Deoxyglucose; Diabetes Mellitus, Experimental; Dinoprostone; Extracellular Space; Glucose; In Vitro Techniques; Insulin; Liver; Prostaglandins E; Rats; Time Factors | 1983 |
A new potentiator of insulin action. Post-receptor activation in vitro.
Topics: Adipose Tissue; Animals; Biological Transport, Active; Blood Glucose; Body Weight; Deoxyglucose; Diabetes Mellitus, Experimental; Drug Synergism; Glucose; Glycolysis; Insulin; Kinetics; Obesity; Rats; Rats, Inbred Strains; Receptor, Insulin; Thiazoles; Thiazolidinediones | 1983 |
Methylamine and monensin do not block insulin internalization but do influence the intracellular distribution and action of insulin in pancreatic acini from diabetic mice.
Topics: Animals; Cell Membrane; Deoxyglucose; Diabetes Mellitus, Experimental; Furans; Golgi Apparatus; Insulin; Leucine; Male; Methylamines; Mice; Microscopy, Electron; Monensin; Pancreas; Vacuoles | 1984 |
Insulin binding sites and action in the adrenal glands from normal and streptozotocin diabetic rats.
Topics: Adrenal Glands; Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Insulin; Male; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Glucose utilization by the mouse brain: influence of age and diabetes.
Topics: Age Factors; Animals; Brain; Deoxyglucose; Diabetes Mellitus, Experimental; Female; Glucose; Mice; Mice, Inbred C57BL | 1984 |
Metabolic fuel and amino acid transport into the brain in experimental diabetes mellitus.
Topics: 3-O-Methylglucose; Amino Acids; Animals; Biological Transport; Biological Transport, Active; Blood-Brain Barrier; Brain; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose; Insulin; Kinetics; Male; Methylglucosides; Rats; Rats, Inbred Strains | 1982 |
Insulin regulation of sugar transport in isolated pancreatic acini from diabetic mice.
Topics: 3-O-Methylglucose; Animals; Biological Transport; Calcium; Cell Movement; Cholecystokinin; Cytoskeleton; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose; Insulin; Male; Membrane Potentials; Methylglucosides; Mice; Pancreas; Time Factors | 1982 |
Fibroblastic cultures from the diabetic db/db mouse. Demonstration of decreased insulin receptors and impaired responses to insulin.
Topics: Animals; Binding, Competitive; Biological Transport, Active; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Experimental; Fibroblasts; Hydrogen-Ion Concentration; Insulin; Kinetics; Male; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Receptor, Insulin; Skin | 1980 |
Effect of insulin on glucagon secretion mediated via glucose metabolism of pancreatic A cells in ducks.
Topics: Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Ducks; Glucagon; Glucose; Glucose Tolerance Test; Insulin; Islets of Langerhans; Male | 1981 |
Pancreatic endocrine function in cortisol-treated thyroidectomized calves.
Topics: Animals; Blood Glucose; Cattle; Deoxyglucose; Diabetes Mellitus, Experimental; Food Deprivation; Hydrocortisone; Islets of Langerhans; Pancreatic Hormones; Secretory Rate; Thyroidectomy | 1981 |
Effect of a high carbohydrate diet on adipocyte glucose metabolism in spontaneously obese rats and insulin-deficient diabetic rats.
Topics: Adipose Tissue; Animals; Biological Transport, Active; Deoxyglucose; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Fatty Acids; Glucose; Glycerides; Kinetics; Male; Obesity; Rats; Triglycerides | 1980 |
Bellidifolin stimulates glucose uptake in rat 1 fibroblasts and ameliorates hyperglycemia in streptozotocin (STZ)-induced diabetic rats.
Topics: Animals; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Experimental; Fibroblasts; Glucose; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Streptozocin; Xanthenes; Xanthones | 1995 |
Overexpression of GLUT3 placental glucose transporter in diabetic rats.
Topics: Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Female; Fluorescent Antibody Technique; Glucose Transporter Type 1; Glucose Transporter Type 3; Insulin; Monosaccharide Transport Proteins; Nerve Tissue Proteins; Placenta; Pregnancy; Rats; Rats, Wistar; RNA, Messenger; Streptozocin | 1995 |
Metabolism of fructose-3-phosphate in the diabetic rat lens.
Topics: Animals; Carbohydrate Metabolism; Crystallins; Deoxyglucose; Diabetes Mellitus, Experimental; Fructosephosphates; Gas Chromatography-Mass Spectrometry; Glycosylation; Hexosephosphates; Lens, Crystalline; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Sugar Phosphates | 1995 |
Excessive glucose production, rather than insulin resistance, accounts for hyperglycaemia in recent-onset streptozotocin-diabetic rats.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Glucagon; Glucose; Glucose Clamp Technique; Glycogen; Glycolysis; Hyperglycemia; Insulin; Insulin Resistance; Liver; Liver Glycogen; Male; Muscle, Skeletal; Myocardium; Organ Specificity; Rats; Rats, Wistar; Reference Values | 1995 |
Effect of insulin-induced hypoglycemia, 2-deoxyglucose-induced glucose cytopenia, and hyperglycemia on cardiovascular tone in normal and diabetic rats.
Topics: Animals; Blood Glucose; Blood Pressure; Deoxyglucose; Diabetes Mellitus, Experimental; Heart Rate; Infusions, Intravenous; Insulin; Male; Models, Biological; Rats; Rats, Wistar | 1994 |
In vivo glycation of aldehyde reductase, a major 3-deoxyglucosone reducing enzyme: identification of glycation sites.
Topics: Aldehyde Reductase; Amino Acid Sequence; Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Glycosylation; Kidney; Liver; Molecular Sequence Data; Oxidation-Reduction; Peptide Mapping; Protein Processing, Post-Translational; Rats | 1995 |
Altered renal expression of the insulin-responsive glucose transporter GLUT4 in experimental diabetes mellitus.
Topics: Animals; Base Sequence; Biological Transport; Deoxyglucose; Diabetes Mellitus, Experimental; DNA Primers; Fluorescent Antibody Technique; Gene Expression; Glucose Transporter Type 4; Immunoblotting; Insulin; Kidney; Kidney Glomerulus; Male; Microcirculation; Molecular Sequence Data; Monosaccharide Transport Proteins; Muscle Proteins; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Reference Values; Renal Artery; Renal Circulation | 1994 |
The effects of severe maternal diabetes on glucose transport in the fetal rat.
Topics: Animals; Biological Transport; Brain; Deoxyglucose; Diabetes Mellitus, Experimental; Embryonic and Fetal Development; Female; Fetus; Glucose; Glucose Transporter Type 1; Monosaccharide Transport Proteins; Muscles; Pregnancy; Pregnancy in Diabetics; Rats; RNA, Messenger | 1994 |
Increase in 3-deoxyglucosone levels in diabetic rat plasma. Specific in vivo determination of intermediate in advanced Maillard reaction.
Topics: 2-Naphthylamine; Animals; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Experimental; Gas Chromatography-Mass Spectrometry; Maillard Reaction; Male; Norleucine; Pyrroles; Rats; Rats, Wistar; Serum Albumin, Bovine; Spectrophotometry, Ultraviolet | 1994 |
Persistence of disturbed adipocyte metabolism in streptozocin-induced diabetic rats despite near-euglycemia with phlorizin.
Topics: Adipocytes; Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose-6-Phosphate; Glucosephosphates; Insulin; Male; Phlorhizin; Rats; Rats, Sprague-Dawley | 1994 |
In-vivo glucose uptake and glucose transporter proteins GLUT1 and GLUT3 in brain tissue from streptozotocin-diabetic rats.
Topics: Animals; Biological Transport, Active; Blood Glucose; Body Weight; Brain; Cell Membrane; Deoxyglucose; Diabetes Mellitus, Experimental; Frontal Lobe; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 3; Immunoblotting; Male; Monosaccharide Transport Proteins; Myocardium; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley | 1993 |
Myocardial glucose transporters and glycolytic metabolism during ischemia in hyperglycemic diabetic swine.
Topics: Animals; Coronary Vessels; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glucose Transporter Type 4; Glycolysis; Hyperglycemia; Lactates; Microspheres; Monosaccharide Transport Proteins; Muscle Proteins; Myocardial Ischemia; Myocardium; Regional Blood Flow; Streptozocin; Swine | 1994 |
In vivo glucose utilization by individual tissues in virgin and pregnant offspring of severely diabetic rats.
Topics: Adipose Tissue; Analysis of Variance; Animals; Blood Glucose; Brain; Deoxyglucose; Diabetes Mellitus, Experimental; Duodenum; Female; Fetus; Glucose; Glucose Clamp Technique; Insulin; Insulin Resistance; Muscles; Placenta; Pregnancy; Pregnancy in Diabetics; Rats; Rats, Wistar; Reference Values | 1993 |
A possible mechanism for increased cerebrovascular permeability in diabetic rats: effects of insulin and 2-deoxy-glucose.
Topics: Animals; Blood Glucose; Capillary Permeability; Cerebrovascular Circulation; Deoxyglucose; Diabetes Mellitus, Experimental; Evans Blue; Insulin; Male; Rats; Rats, Wistar | 1993 |
Improvement of insulin action in diabetic transgenic mice selectively overexpressing GLUT4 in skeletal muscle.
Topics: Adipose Tissue; Animals; Biological Transport; Blood Glucose; Blotting, Northern; Blotting, Western; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Gene Expression; Glucose Tolerance Test; Glucose Transporter Type 4; Injections, Intraperitoneal; Insulin; Male; Mice; Mice, Inbred CBA; Mice, Transgenic; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; RNA, Messenger | 1996 |
Characterization of [2-3H]deoxy-D-glucose uptake in retina and retinal pigment epithelium of normal and diabetic rats.
Topics: Animals; Antimetabolites; Deoxyglucose; Diabetes Mellitus, Experimental; Energy Metabolism; Extracellular Space; Homeostasis; Hypoglycemic Agents; Insulin; Kinetics; Pigment Epithelium of Eye; Rats; Retina | 1996 |
Aldose reductase and sorbitol dehydrogenase activities in diabetic brain: in vivo kinetic studies using 19F 3-FDG NMR in rats.
Topics: Aldehyde Reductase; Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Kinetics; L-Iditol 2-Dehydrogenase; Magnetic Resonance Spectroscopy; Rats; Rats, Sprague-Dawley | 1996 |
Serum levels of 3-deoxyglucosone and tissue contents of advanced glycation end products are increased in streptozotocin-induced diabetic rats with nephropathy.
Topics: Animals; Antibodies, Monoclonal; Body Weight; Creatinine; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Kidney; Male; Proteinuria; Rats; Rats, Wistar; Urea | 1996 |
Glucose transport and glucose transporter GLUT4 are regulated by product(s) of intermediary metabolism in cardiomyocytes.
Topics: 3-Hydroxybutyric Acid; 3-O-Methylglucose; Animals; Biological Transport; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Experimental; Energy Metabolism; Enzyme Inhibitors; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Hydroxybutyrates; Insulin; Lactic Acid; Monosaccharide Transport Proteins; Muscle Proteins; Myocardium; Phenylephrine; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Rats, Wistar; Substrate Specificity; Transaminases | 1997 |
Dietary guar gum improves insulin sensitivity in streptozotocin-induced diabetic rats.
Topics: Adipose Tissue; Animals; Blood Glucose; Cholesterol; Deoxyglucose; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Dietary Fiber; Eating; Galactans; Glucose Clamp Technique; Infusions, Intravenous; Insulin; Male; Mannans; Muscle, Skeletal; Plant Gums; Random Allocation; Rats; Rats, Sprague-Dawley; Streptozocin; Triglycerides; Weight Gain | 1997 |
Characterization of 6-deoxy-6-iodo-D-glucose: a potential new tool to assess glucose transport.
Topics: 3-O-Methylglucose; Adipocytes; Animals; Biological Transport; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose; Male; Mice; Mice, Obese; Rats; Rats, Wistar | 1997 |
Inhibitory effects of tenilsetam on the Maillard reaction.
Topics: Animals; Aorta; Blood Glucose; Collagen; Deoxyglucose; Diabetes Mellitus, Experimental; Fructose; Glucose; Glycated Hemoglobin; Kidney Cortex; Macromolecular Substances; Maillard Reaction; Male; Muramidase; Norleucine; Piperazines; Psychotropic Drugs; Pyrroles; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Thiophenes | 1997 |
Imidazolone, a novel advanced glycation end product, is present at high levels in kidneys of rats with streptozotocin-induced diabetes.
Topics: Animals; Antibodies, Monoclonal; Arginine; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glycation End Products, Advanced; Imidazoles; Kidney; Kinetics; Maillard Reaction; Male; Mice; Rats; Rats, Wistar | 1997 |
Lipoic acid reduces glycemia and increases muscle GLUT4 content in streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose Transporter Type 4; In Vitro Techniques; Insulin; Lactic Acid; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thioctic Acid | 1997 |
Pancreatic and extra-pancreatic effects of the traditional anti-diabetic plant, Medicago sativa (lucerne).
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antihypertensive Agents; Biological Transport; Culture Techniques; Deoxyglucose; Diabetes Mellitus, Experimental; Diazoxide; Glucose; Glycogen; Insulin; Insulin Secretion; Islets of Langerhans; Male; Medicago sativa; Medicine, Traditional; Mice; Muscle, Skeletal; Phosphodiesterase Inhibitors; Phytotherapy; Plant Extracts; Stimulation, Chemical | 1997 |
Impaired insulin but normal pentagastrin effect on gastric acid secretion in diabetic rats: a role for nitric oxide.
Topics: Animals; Antimetabolites; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fasting; Gastric Acid; Glucose; Hypoglycemia; Hypoglycemic Agents; Insulin; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentagastrin; Rats; Rats, Wistar; Time Factors | 1997 |
Fructose-3-phosphate production and polyol pathway metabolism in diabetic rat hearts.
Topics: Administration, Oral; Ampholyte Mixtures; Animals; Chromatography, High Pressure Liquid; Cohort Studies; Deoxyglucose; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructose; Fructosephosphates; Gas Chromatography-Mass Spectrometry; Glucose; Imidazoles; Imidazolidines; Lens, Crystalline; Magnetic Resonance Spectroscopy; Male; Myocardium; Perchlorates; Phosphorus Isotopes; Polymers; Rats; Rats, Sprague-Dawley; Sorbitol | 1997 |
Interaction between BTBR and C57BL/6J genomes produces an insulin resistance syndrome in (BTBR x C57BL/6J) F1 mice.
Topics: Adipose Tissue; Animals; Biological Transport, Active; Body Weight; Crosses, Genetic; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Female; Genotype; Glucose Tolerance Test; Glucose Transporter Type 4; Hyperlipidemias; Hypoxia; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Organ Size; Sex Characteristics | 1997 |
HCO3(-)-dependent alkalinizing transporter in adult rat ventricular myocytes: characterization and modulation.
Topics: Amiloride; Animals; Bicarbonates; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cells, Cultured; Chlorides; Deoxyglucose; Diabetes Mellitus, Experimental; Glycolysis; Heart; Heart Ventricles; Hydrogen-Ion Concentration; Male; Myocardium; Rats; Rats, Wistar; Reference Values; Sodium; Sodium-Bicarbonate Symporters | 1997 |
Glycemia-lowering effect of cobalt chloride in the diabetic rat: role of decreased gluconeogenesis.
Topics: Animals; Blood Glucose; Cobalt; Deoxyglucose; Diabetes Mellitus, Experimental; Eye; Fasting; Gluconeogenesis; Hypoglycemic Agents; Kidney; Liver; Male; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Sprague-Dawley; RNA, Messenger; Tritium | 1998 |
Maternal hyperglycemia alters glucose transport and utilization in mouse preimplantation embryos.
Topics: Animals; Biological Transport; Blastocyst; Chorionic Gonadotropin; Deoxyglucose; Diabetes Mellitus, Experimental; Embryonic and Fetal Development; Female; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 2; Glucose Transporter Type 3; Hexokinase; Hyperglycemia; Mice; Mice, Inbred Strains; Monosaccharide Transport Proteins; Nerve Tissue Proteins; Polymerase Chain Reaction; Pregnancy; Pregnancy in Diabetics; Reference Values | 1998 |
Teratogenicity of 3-deoxyglucosone and diabetic embryopathy.
Topics: Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Glucose; Glyoxal; Hyperglycemia; Male; Pregnancy; Pyruvaldehyde; Rats; Teratogens | 1998 |
Low susceptibility of stress ulcer in diabetic rats: role of cholinergic gastric motility.
Topics: Animals; Antiemetics; Antimetabolites; Atropine; Bethanechol; Blood Glucose; Body Weight; Cholinergic Fibers; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Susceptibility; Drinking Behavior; Gastric Emptying; Gastric Mucosa; Glutathione; Male; Metoclopramide; Parasympatholytics; Parasympathomimetics; Polyuria; Rats; Rats, Wistar; Stomach Ulcer; Stress, Physiological; Vagotomy | 1998 |
High concentration of glucose decreases glucose transporter-1 expression in mouse placenta in vitro and in vivo.
Topics: Animals; Blotting, Northern; Cells, Cultured; Cytochalasin B; Deoxyglucose; Diabetes Mellitus, Experimental; Female; Glucose Transporter Type 1; Immunoblotting; Leucine; Mice; Mice, Inbred ICR; Monosaccharide Transport Proteins; Placenta; Pregnancy; Pregnancy in Diabetics; Protein Binding; RNA, Messenger; Serotonin | 1999 |
Diabetes mellitus preserves synaptic plasticity in hippocampal slices from middle-aged rats.
Topics: Aging; Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Male; Neuronal Plasticity; Rats; Rats, Wistar; Synapses | 1999 |
Hypothalamic orexin expression: modulation by blood glucose and feeding.
Topics: Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Eating; Fasting; Food Deprivation; Gene Expression Regulation; Hyperphagia; Hypoglycemia; Hypothalamic Area, Lateral; Insulin; Intracellular Signaling Peptides and Proteins; Leptin; Male; Neurons; Neuropeptides; Orexins; Protein Precursors; Rats; Rats, Sprague-Dawley; Rats, Wistar; Transcription, Genetic | 1999 |
Metabolic control of sodium transport in streptozotocin-induced diabetic rat hearts.
Topics: 2,4-Dinitrophenol; Animals; Antimetabolites; Biological Transport; Case-Control Studies; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Male; Myocardium; Ouabain; Perfusion; Phosphorylation; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Potassium-Exchanging ATPase; Streptozocin; Time Factors; Uncoupling Agents | 2000 |
Fate of 6-deoxy-6-[123I]iodo-D-glucose in normal and diabetic rats.
Topics: Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Female; Glucose; Injections, Intraperitoneal; Iodine Radioisotopes; Organ Specificity; Rats; Rats, Wistar; Streptozocin | 2000 |
Insulin-like effect of pinitol.
Topics: Animals; Blood Glucose; Cell Line; Chromones; Deoxyglucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Inositol; Insulin; Mice; Mice, Obese; Morpholines; Muscles; Obesity; Phosphoinositide-3 Kinase Inhibitors; Time Factors | 2000 |
Pancreatic fate of 6-deoxy-6-[125I]iodo-D-glucose: in vitro experiments.
Topics: Animals; Cytochalasin B; Deoxyglucose; Diabetes Mellitus, Experimental; Female; In Vitro Techniques; Iodine Radioisotopes; Islets of Langerhans; Kinetics; Pancreas; Rats; Rats, Wistar | 2000 |
Pancreatic fate of 6-deoxy-6-[125I]iodo-D-glucose: in vivo experiments.
Topics: Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Erythrocytes; Female; Glomerular Filtration Rate; Injections, Intravenous; Insulin; Iodine Radioisotopes; Islets of Langerhans; Kinetics; Liver; Muscles; Pancreas; Rats; Rats, Wistar | 2000 |
Correction of hyperglycemia and insulin sensitivity by T-1095, an inhibitor of renal Na+-glucose cotransporters, in streptozotocin-induced diabetic rats.
Topics: Animals; Carbonates; Deoxyglucose; Diabetes Mellitus, Experimental; Glucosides; Hyperglycemia; Hypoglycemic Agents; In Vitro Techniques; Insulin Resistance; Lactic Acid; Male; Monosaccharide Transport Proteins; Muscle, Skeletal; Rats | 2000 |
Pancreatic fate of 6-deoxy-6-[125I]iodo-D-glucose: in vitro experiments.
Topics: 3-O-Methylglucose; Animals; Carbon Radioisotopes; Cytochalasin B; Deoxyglucose; Diabetes Mellitus, Experimental; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Iodine Radioisotopes; Islets of Langerhans; Kinetics; Pancreas; Rats; Rats, Wistar; Tissue Distribution; Tritium | 2000 |
A beta3-adrenergic agonist increases muscle GLUT1/GLUT4 ratio, and regulates liver glucose utilization in diabetic rats.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Animals; Benzyl Alcohols; Deoxyglucose; Diabetes Mellitus, Experimental; Female; Gene Expression; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Liver; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
Inhibitory effect of hyperglycemia on insulin-induced Akt/protein kinase B activation in skeletal muscle.
Topics: Animals; Biological Transport; Deoxyglucose; Diabetes Mellitus, Experimental; Enzyme Activation; Glucose; Glucose Transporter Type 4; Hyperglycemia; Insulin; Intracellular Membranes; Lactic Acid; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Oxidation-Reduction; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction | 2001 |
High glucose concentrations stimulate renal papillary phosphatidylcholine biosynthesis.
Topics: Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Kidney Medulla; Male; Microsomes; Neomycin; Phosphatidylcholines; Rats; Rats, Wistar | 2001 |
Differential impairment of glucagon responses to hypoglycemia, neuroglycopenia, arginine, and carbachol in alloxan-diabetic mice.
Topics: Animals; Arginine; Brain; Carbachol; Deoxyglucose; Diabetes Mellitus, Experimental; Female; Glucagon; Glucose; Hypoglycemia; Hypoglycemic Agents; Insulin; Mice; Mice, Inbred Strains | 2002 |
Imaging of ischemic but viable myocardium using a new 18F-labeled 2-nitroimidazole analog, 18F-FRP170.
Topics: Animals; Antipyrine; Autoradiography; Carbon Radioisotopes; Deoxyglucose; Diabetes Mellitus, Experimental; Fatty Acids; Fluorine Radioisotopes; Glucose; Heart; Iodine Radioisotopes; Iodobenzenes; Male; Myocardial Ischemia; Myocardium; Nitroimidazoles; Nucleosides; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar | 2002 |
DYN 12, a small molecule inhibitor of the enzyme amadorase, lowers plasma 3-deoxyglucosone levels in diabetic rats.
Topics: Amino Acid Oxidoreductases; Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Enzyme Inhibitors; Glycation End Products, Advanced; Humans; Kidney Glomerulus; Organic Chemicals; Phosphotransferases (Alcohol Group Acceptor); Rats; Reference Values | 2001 |
Comparison between spontaneously beating atria from control and streptozocin-diabetic rats.
Topics: Acetates; Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose; Heart Rate; In Vitro Techniques; Insulin; Male; Methylglucosides; Myocardial Contraction; Rats | 1978 |
Studies on streptozotocin diabetes.
Topics: Alloxan; Animals; Blood Glucose; Deoxy Sugars; Deoxyglucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucose; Islets of Langerhans; Male; Mannoheptulose; Mannose; Methylglucosides; Methylglycosides; Rats; Streptozocin; Structure-Activity Relationship; Time Factors | 1976 |
Insulin binding and glucose metabolism in adipocytes of streptozotocin-diabetic rats.
Topics: Adipose Tissue; Animals; Biological Transport; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose; Insulin; Male; Rats; Streptozocin | 1978 |
Effect of fasting and streptozotocin diabetes on insulin binding and action in the isolated mouse soleus muscle.
Topics: Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Enzyme Activation; Fasting; Glucose; Glycogen; Glycogen Synthase; Glycolysis; Hindlimb; Insulin; Insulin Resistance; Mice; Muscle Proteins; Muscles; Receptor, Insulin; Streptozocin | 1979 |
Effects of insulin and diabetes on 2-deoxy-D-glucose uptake by the isolated perfused rat lung.
Topics: Animals; Biological Transport, Active; Deoxy Sugars; Deoxyglucose; Diabetes Mellitus, Experimental; In Vitro Techniques; Insulin; Kinetics; Lung; Male; Perfusion; Phosphoric Monoester Hydrolases; Rats | 1979 |
Reduced glucose transport and increased binding of insulin in adipocytes from diabetic and fasted rats.
Topics: Adipose Tissue; Animals; Carbon Dioxide; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose; Insulin; Kinetics; Male; Rats; Receptor, Insulin; Starvation | 1978 |
Long-term regulation of adipocyte glucose transport capacity by circulating insulin in rats.
Topics: Adipose Tissue; Animals; Biological Transport; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Kinetics; Male; Rats | 1978 |
Ability of circulating insulin to chronically regulate the cellular glucose transport system.
Topics: Adipose Tissue; Animals; Biological Transport, Active; Blood Glucose; Cytochalasin B; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucose; Hyperinsulinism; Insulin; Kinetics; Male; Rats | 1978 |
Central metabolic and humoral factors involved in the neural regulation of feeding.
Topics: Adipose Tissue; Aging; Amino Acids; Animals; Circadian Rhythm; Deoxyglucose; Diabetes Mellitus, Experimental; Dietary Fats; Eating; Fasting; Feeding Behavior; Glucose; Hypothalamus; Linoleic Acids; Liver; Models, Biological; Oxygen Consumption; Rats; Time Factors; Urea | 1975 |
Diabetic state-induced modification of insulin-stimulated, glucose uptake into and kinase activity in, the diaphragm muscle of genetically diabetic KK-CAy mice.
Topics: Animals; Blood Glucose; Body Weight; Deoxyglucose; Diabetes Mellitus, Experimental; Diaphragm; Glucose; Insulin; Male; Mice; Mice, Inbred Strains; Muscles; Phosphotransferases | 1992 |
Effect of streptozotocin-induced diabetes on GLUT-4 phosphorylation in rat adipocytes.
Topics: Adipose Tissue; Animals; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Experimental; Insulin; Male; Monosaccharide Transport Proteins; Phosphoric Monoester Hydrolases; Phosphorylation; Rats; Rats, Sprague-Dawley; Streptozocin | 1992 |
Distribution of 1,5-anhydro-D-glucitol in normal, diabetic, and perfused rat bodies.
Topics: Animals; Deoxyglucose; Diabetes Mellitus, Experimental; In Vitro Techniques; Intracellular Fluid; Male; Perfusion; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1992 |
Placental transfer and uptake of 2-deoxyglucose in control and diabetic rats.
Topics: Animals; Body Weight; Deoxyglucose; Diabetes Mellitus, Experimental; Female; Fetus; Maternal-Fetal Exchange; Placenta; Pregnancy; Rats; Streptozocin | 1992 |
The contribution of hyperglycaemia and hypoinsulinaemia to the insulin resistance of streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Eating; Fasting; Glucose; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Liver; Male; Organ Specificity; Rats; Rats, Zucker; Reference Values | 1992 |
Insulin action and determinants of glycaemia in a rat model of type 2 (non-insulin-dependent) diabetes mellitus.
Topics: Adipose Tissue; Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Dietary Fats; Eating; Energy Intake; Glucose; Glucose Clamp Technique; Insulin; Male; Muscles; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Reference Values; Tritium | 1992 |
Effect of chromium administration on glucose tolerance in stroke-prone spontaneously hypertensive rats with streptozotocin-induced diabetes.
Topics: Animals; Cerebrovascular Disorders; Chromium; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1992 |
Putative role of endogenous insulin in cysteamine-induced hypersecretion of gastric acid in rats.
Topics: Animals; Blood Glucose; Brain Chemistry; Cysteamine; Deoxyglucose; Diabetes Mellitus, Experimental; Gastric Acid; Gastric Mucosa; Glucagon; Glucose; Insulin; Male; Peptic Ulcer; Rats; Rats, Inbred Strains | 1991 |
Increased insulin action in rats with mild insulin deficiency induced by neonatal streptozotocin.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Animals, Newborn; Blood Glucose; Brain; Deoxyglucose; Diabetes Mellitus, Experimental; Female; Glucose; Glucose Clamp Technique; Insulin; Muscles; Rats; Rats, Inbred Strains; Reference Values; Streptozocin | 1991 |
Influence of streptozotocin-induced diabetes on adenylate cyclase activity in cultured type II pneumocytes.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Deoxyglucose; Diabetes Mellitus, Experimental; Guanosine Triphosphate; Insulin; Isoproterenol; Lung; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Receptor, Insulin; Sodium Fluoride; Streptozocin | 1991 |
Enhanced 2-deoxy-D-glucose uptake and metabolism in splenocytes from diabetic and diabetes-prone BB rats. Further evidence to support prior in vivo activation.
Topics: Animals; Carbon Dioxide; Deoxyglucose; Diabetes Mellitus, Experimental; Female; Glucose; Lactates; Lactic Acid; Male; Mitogens; Pyruvates; Rats; Spleen | 1991 |
Direct vital microscopic study of defective leukocyte-endothelial interaction in diabetes mellitus.
Topics: Animals; Arachidonic Acid; Cell Adhesion; Deoxyglucose; Diabetes Mellitus, Experimental; Endothelium, Vascular; Insulin; Leukocytes; Male; Rats; Rats, Inbred Strains | 1991 |
Peripheral insulin insensitivity in the hyperglycemic athymic nude mouse: similarity to noninsulin-dependent diabetes mellitus.
Topics: Animals; Biological Transport, Active; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Islets of Langerhans; Male; Mice; Mice, Nude; Muscles | 1991 |
Interrelated effects of insulin and glucose on diacylglycerol-protein kinase-C signalling in rat adipocytes and solei muscle in vitro and in vivo in diabetic rats.
Topics: Adipose Tissue; Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Diglycerides; Epididymis; Glucose; Glycerol; Insulin; Lipid Metabolism; Male; Muscles; Protein Kinase C; Rats; Signal Transduction | 1991 |
[Clinical significance of plasma 1,5-anhydroglucitol analysis in the diagnosis of diabetes mellitus].
Topics: Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Humans; Kidney; Rats; Reference Values | 1990 |
Isolation of insulin-sensitive phosphatidylinositol-glycan from rat adipocytes. Its impaired breakdown in the streptozotocin-diabetic rat.
Topics: Adipose Tissue; Animals; Cell Membrane; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Experimental; Glucosamine; Glycosylphosphatidylinositols; Insulin; Male; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Polysaccharides; Rats; Rats, Inbred Strains | 1990 |
Participation of the CNS in the control of FFA mobilization during fasting in rabbits.
Topics: Adrenal Medulla; Animals; Blood Glucose; Brain; Deoxyglucose; Diabetes Mellitus, Experimental; Fasting; Fatty Acids, Nonesterified; Injections, Intraventricular; Insulin; Male; Rabbits | 1990 |
Identification of fructose 3-phosphate in the lens of diabetic rats.
Topics: Animals; Cross-Linking Reagents; Deoxyglucose; Diabetes Mellitus, Experimental; Fructose-Bisphosphate Aldolase; Fructosephosphates; Glycosylation; Hydrolysis; L-Lactate Dehydrogenase; Lens, Crystalline; Magnetic Resonance Spectroscopy; Rats | 1990 |
Regional brain glucose metabolism and blood flow in streptozocin-induced diabetic rats.
Topics: Aging; Animals; Antipyrine; Autoradiography; Brain; Carbon Radioisotopes; Cerebrovascular Circulation; Deoxy Sugars; Deoxyglucose; Diabetes Mellitus, Experimental; Male; Organ Specificity; Rats; Rats, Inbred Strains; Reference Values; Regional Blood Flow; Tritium | 1990 |
Glucose phosphorylation rate in rat parietal cortex during normoglycemia, hypoglycemia, acute hyperglycemia, and in diabetes-prone rats.
Topics: Animals; Deoxy Sugars; Deoxyglucose; Diabetes Mellitus, Experimental; Hyperglycemia; Hypoglycemia; Male; Parietal Lobe; Phosphorylation; Rats; Rats, Inbred Strains | 1990 |
In vitro effects of sulfonylurea on glucose transport and translocation of glucose transporters in adipocytes from streptozocin-induced diabetic rats.
Topics: Adipose Tissue; Animals; Biological Transport, Active; Cell Membrane; Cells, Cultured; Cytochalasin B; Deoxy Sugars; Deoxyglucose; Diabetes Mellitus, Experimental; Glyburide; Kinetics; Male; Monosaccharide Transport Proteins; Rats; Receptor, Insulin; Reference Values | 1989 |
New diabetogenic streptozocin analogue, 3-O-methyl-2-([(methylnitrosoamino) carbonyl]amino)-D-glucopyranose. Evidence for a glucose recognition site on pancreatic B-cells.
Topics: 3-O-Methylglucose; Acetylglucosamine; Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose; Hyperglycemia; Islets of Langerhans; Male; Methylglucosides; Rats; Rats, Inbred Strains; Streptozocin | 1986 |
Marked depletion of plasma 1,5-anhydroglucitol, a major polyol, in streptozocin-induced diabetes in rats and the effect of insulin treatment.
Topics: Animals; Blood Glucose; Chromatography, Gas; Deoxy Sugars; Deoxyglucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Humans; Insulin; Male; Rats; Rats, Inbred Strains; Streptozocin; Time Factors; Tissue Distribution | 1986 |
Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats.
Topics: Adipose Tissue; Animals; Benzopyrans; Blood Glucose; Chromans; Deoxyglucose; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Insulin Resistance; Ketone Bodies; Lactates; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Rats; Rats, Inbred Strains; Rats, Zucker; Receptor, Insulin; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone | 1988 |
Effect of duration of diabetic state on insulin action in isolated rat soleus muscles.
Topics: Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose; Glycogen; Glycogen Synthase; Insulin; Insulin Resistance; Male; Muscles; Rats; Rats, Inbred Strains; Receptor, Insulin | 1986 |
Insulin action on glucose uptake by soleus muscles of nonobese diabetic mice and streptozotocin diabetic mice.
Topics: Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Glucose; Insulin; Male; Mice; Mice, Inbred ICR; Muscles; Sex Factors | 1988 |
Autoradiographic determination of cerebral glucose content, blood flow, and glucose utilization in focal ischemia of the rat brain: influence of the plasma glucose concentration.
Topics: Animals; Autoradiography; Blood Flow Velocity; Blood Glucose; Brain; Cerebrovascular Circulation; Corpus Striatum; Deoxyglucose; Diabetes Mellitus, Experimental; Frontal Lobe; Ischemic Attack, Transient; Male; Rats; Rats, Inbred Strains | 1988 |
Temperature dependence of glucose transport in erythrocytes from normal and alloxan-diabetic rats.
Topics: 3-O-Methylglucose; Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Erythrocyte Membrane; Erythrocytes; Kinetics; Membrane Lipids; Methylglucosides; Rats; Rats, Inbred Strains; Reference Values; Temperature; Xylose | 1988 |
Regional brain glucose uptake in genetically diabetic C57BL/KsJ mice: modulation by the opiate antagonist, nalmefene.
Topics: Animals; Brain; Deoxy Sugars; Deoxyglucose; Diabetes Mellitus, Experimental; Female; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Naltrexone; Narcotic Antagonists; Organ Specificity; Reference Values | 1988 |
Membrane-transport of sugars in diabetes mellitus.
Topics: Animals; Biological Transport; Carbohydrate Metabolism; Deoxyglucose; Diabetes Mellitus, Experimental; Intestinal Mucosa; Intestine, Small; Male; Methylglucosides; Rats; Rats, Inbred Strains | 1988 |
Reduced renal reabsorption of 1,5-anhydro-D-glucitol in diabetic rats and mice.
Topics: Absorption; Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Deoxy Sugars; Deoxyglucose; Diabetes Mellitus, Experimental; Gas Chromatography-Mass Spectrometry; Glycosuria; Kidney; Male; Mice; Mice, Inbred ICR; Rats; Rats, Inbred Strains; Tissue Distribution | 1987 |
Contraluminal transport of hexoses in the proximal convolution of the rat kidney in situ.
Topics: Animals; Biological Transport; Chlormerodrin; Deoxyglucose; Diabetes Mellitus, Experimental; Hexoses; Insulin; Kidney Tubules, Proximal; Kinetics; Male; Perfusion; Phloretin; Rats; Sodium; Tritium | 1985 |