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deoxyepinephrine and Encephalopathy, Toxic

deoxyepinephrine has been researched along with Encephalopathy, Toxic in 5 studies

Deoxyepinephrine: Sympathomimetic, vasoconstrictor agent.

Research Excerpts

ExcerptRelevanceReference
" We showed that MDMA metabolites exhibited toxicity to SH-SY5Y differentiated cells, being the GSH and NAC conjugates more toxic than their catecholic precursors and MDMA."1.40"Ecstasy"-induced toxicity in SH-SY5Y differentiated cells: role of hyperthermia and metabolites. ( Barbosa, DJ; Bastos, ML; Branco, PS; Capela, JP; Carvalho, F; Fernandes, E; Ferreira, LM; Silva, R, 2014)
"3,4-Methylenedioxymethamphetamine (MDMA)'s O-demethylenated metabolite, 3,4-dihydroxymethamphetamine (HHMA), has been hypothesized to serve as a precursor for the formation of toxic catechol-thioether metabolites (e."1.37Inhibition of 3,4-methylenedioxymethamphetamine metabolism leads to marked decrease in 3,4-dihydroxymethamphetamine formation but no change in serotonin neurotoxicity: implications for mechanisms of neurotoxicity. ( Maldonado Adrian, C; McCann, UD; Mueller, M; Ricaurte, GA; Yuan, J, 2011)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barbosa, DJ2
Capela, JP2
Silva, R2
Vilas-Boas, V1
Ferreira, LM2
Branco, PS2
Fernandes, E2
Bastos, Mde L1
Carvalho, F2
Bastos, ML1
Mueller, M2
Yuan, J2
Felim, A1
Neudörffer, A1
Peters, FT1
Maurer, HH1
McCann, UD2
Largeron, M1
Ricaurte, GA2
Escubedo, E1
Abad, S1
Torres, I1
Camarasa, J1
Pubill, D1
Maldonado Adrian, C1

Other Studies

5 other studies available for deoxyepinephrine and Encephalopathy, Toxic

ArticleYear
The mixture of "ecstasy" and its metabolites is toxic to human SH-SY5Y differentiated cells at in vivo relevant concentrations.
    Archives of toxicology, 2014, Volume: 88, Issue:2

    Topics: Acetylcysteine; Calcium; Caspase 3; Cell Differentiation; Cell Line; Deoxyepinephrine; Dopamine; Dop

2014
"Ecstasy"-induced toxicity in SH-SY5Y differentiated cells: role of hyperthermia and metabolites.
    Archives of toxicology, 2014, Volume: 88, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Acetylcysteine; Caspase 3; Cell Death; Cell Differentiation; Cell Lin

2014
Further studies on the role of metabolites in (+/-)-3,4-methylenedioxymethamphetamine-induced serotonergic neurotoxicity.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Deoxyepinephrine; Disease Models, Animal; Male; N-Methyl-3,4

2009
Comparative neurochemical profile of 3,4-methylenedioxymethamphetamine and its metabolite alpha-methyldopamine on key targets of MDMA neurotoxicity.
    Neurochemistry international, 2011, Volume: 58, Issue:1

    Topics: Animals; Cell Membrane; Cell Survival; Cocaine; Deoxyepinephrine; Dopamine; Dopamine Plasma Membrane

2011
Inhibition of 3,4-methylenedioxymethamphetamine metabolism leads to marked decrease in 3,4-dihydroxymethamphetamine formation but no change in serotonin neurotoxicity: implications for mechanisms of neurotoxicity.
    Synapse (New York, N.Y.), 2011, Volume: 65, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme

2011