deoxycytidine and Liver Dysfunction

deoxycytidine has been researched along with Liver Dysfunction in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.26)18.2507
2000's9 (47.37)29.6817
2010's9 (47.37)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bergeat, D; Coulouarn, C; De La Torre, C; Dooley, S; Ebert, MPA; Gretz, N; Li, J; Liebe, R; Lin, T; Sulpice, L; Weng, HL; Yuan, X1
Endo, I; Hata, M; Homma, Y; Ito, E; Kaizu, H; Koike, I; Kumamoto, T; Matsuyama, R; Mukai, Y; Sato, M; Sawada, Y; Sugiura, M; Takano, S; Yabushita, Y1
Beijnen, JH; Cerny, T; Gillessen, S; Hitz, F; Huitema, AD; Joerger, M; Koeberle, D; Rosing, H; Schellens, JH1
Abali, H; Köse, F; Mertsoylu, H; Muallaoğlu, S; Ozyilkan, O; Sezer, A; Sümbül, AT1
Ando, Y; Ebata, T; Fujita, K; Maeda, O; Mitsuma, A; Nagino, M; Sasaki, Y; Shibata, T; Shimokata, T1
Citro, G; Cognetti, F; Colantonio, S; Contestabile, M; Di Segni, S; Felici, A; Milella, M; Nuvoli, B; Sacconi, A; Sperduti, I; Zaratti, M1
Arab, K; Bartsch, H; Fucharoen, S; Kalpravidh, R; Meerang, M; Nair, J; Sirankapracha, P; Srichairatanakool, S; Thephinlap, C; Vadolas, J1
Endo, S; Hashimoto, K; Iguchi, C; Itakura, M; Koike, M; Nio, Y; Nishi, T; Omori, H; Sato, Y; Takamura, M; Takeda, H1
Hall, PD; Teusink, AC1
Marshall, JL; Mikhail, SE; Sun, JF1
Naggie, S; Sulkowski, MS1
Aspillaga M, A; Buttinghausen, V; Chandía C, M; Orellana, M1
Curran, MP; Plosker, GL1
Eklund, JW; Mulcahy, MF; Trifilio, S1
Saadati, H; Saif, MW1
Banken, L; Cassidy, J; Glynne-Jones, R; Goggin, T; Reigner, B; Roos, B; Schüller, J; Twelves, C; Utoh, M; Weidekamm, E1
Budman, D; Byrd, J; Egorin, MJ; Hawkins, M; Hohl, R; Hollis, D; Mani, S; Meropol, NJ; Ratain, MJ; Rosner, GL; Venook, AP1
Blesch, K; Reigner, B; Weidekamm, E1

Reviews

5 review(s) available for deoxycytidine and Liver Dysfunction

ArticleYear
Safety of capecitabine: a review.
    Expert opinion on drug safety, 2010, Volume: 9, Issue:5

    Topics: Adult; Age Factors; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials as Topic; Comorbidity; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Gastrointestinal Diseases; Humans; Hyperbilirubinemia; Kidney Diseases; Liver Diseases; Male; Multicenter Studies as Topic; Neoplasms; Paresthesia; Randomized Controlled Trials as Topic; Retrospective Studies; Vulnerable Populations

2010
Management of patients coinfected with HCV and HIV: a close look at the role for direct-acting antivirals.
    Gastroenterology, 2012, Volume: 142, Issue:6

    Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Coinfection; Deoxycytidine; Dideoxynucleosides; Disease Progression; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Emtricitabine; Hepatitis C, Chronic; HIV Infections; Homosexuality, Male; Humans; Interferon-alpha; Lamivudine; Liver Cirrhosis; Liver Diseases; Male; Oligopeptides; Organophosphonates; Polyethylene Glycols; Proline; Pyrrolidinones; Raltegravir Potassium; Recombinant Proteins; Ribavirin; Serine Proteinase Inhibitors; Substance Abuse, Intravenous; Tenofovir; Treatment Outcome

2012
Vinorelbine: a review of its use in elderly patients with advanced non-small cell lung cancer.
    Drugs & aging, 2002, Volume: 19, Issue:9

    Topics: Age Factors; Aged; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Humans; Injections, Intravenous; Liver Diseases; Lung Neoplasms; Vinblastine; Vinorelbine

2002
Chemotherapy dosing in the setting of liver dysfunction.
    Oncology (Williston Park, N.Y.), 2005, Volume: 19, Issue:8

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Gemcitabine; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Maximum Tolerated Dose; Neoplasms; Randomized Controlled Trials as Topic; Risk Assessment; Topotecan

2005
Clinical pharmacokinetics of capecitabine.
    Clinical pharmacokinetics, 2001, Volume: 40, Issue:2

    Topics: Antacids; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Docetaxel; Dose-Response Relationship, Drug; Drug Interactions; Fluorouracil; Food; Humans; Intestinal Absorption; Leucovorin; Liver Diseases; Paclitaxel; Protein Binding; Taxoids

2001

Trials

2 trial(s) available for deoxycytidine and Liver Dysfunction

ArticleYear
Optimal dose of gemcitabine for the treatment of biliary tract or pancreatic cancer in patients with liver dysfunction.
    Cancer science, 2016, Volume: 107, Issue:2

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biliary Tract Neoplasms; Deoxycytidine; Dose-Response Relationship, Drug; Female; Gemcitabine; Humans; Liver; Liver Diseases; Male; Middle Aged; Pancreatic Neoplasms

2016
Phase I and pharmacokinetic trial of gemcitabine in patients with hepatic or renal dysfunction: Cancer and Leukemia Group B 9565.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:14

    Topics: Aged; Antimetabolites, Antineoplastic; Aspartate Aminotransferases; Bilirubin; Creatinine; Deoxycytidine; Female; Gemcitabine; Humans; Liver Diseases; Liver Function Tests; Male; Middle Aged; Models, Biological; Neoplasms; Renal Insufficiency

2000

Other Studies

12 other study(ies) available for deoxycytidine and Liver Dysfunction

ArticleYear
SOX9 expression decreases survival of patients with intrahepatic cholangiocarcinoma by conferring chemoresistance.
    British journal of cancer, 2018, Volume: 119, Issue:11

    Topics: Antineoplastic Agents; Bile Duct Neoplasms; Biomarkers, Tumor; Cell Proliferation; Cholangiocarcinoma; Chronic Disease; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Humans; Liver Diseases; SOX9 Transcription Factor; Survival Analysis; Treatment Outcome

2018
Outcome of postoperative radiation therapy for cholangiocarcinoma and analysis of dose-volume histogram of remnant liver.
    Medicine, 2019, Volume: 98, Issue:31

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cholangiocarcinoma; Cisplatin; Combined Modality Therapy; Deoxycytidine; Drug Combinations; Gemcitabine; Hepatectomy; Humans; Kaplan-Meier Estimate; Liver Diseases; Liver Neoplasms; Middle Aged; Neoplasm Staging; Oxonic Acid; Pyridines; Radiation Injuries; Radiation-Sensitizing Agents; Radiotherapy Dosage; Radiotherapy, Adjuvant; Tegafur; Tomography, X-Ray Computed

2019
Safety and pharmacology of gemcitabine and capecitabine in patients with advanced pancreatico-biliary cancer and hepatic dysfunction.
    Cancer chemotherapy and pharmacology, 2014, Volume: 73, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Capecitabine; Deoxycytidine; Female; Fluorouracil; Gemcitabine; Humans; Hyperbilirubinemia; Liver Diseases; Male; Middle Aged; Pancreatic Neoplasms

2014
Gemcitabine + platinum combination chemotherapy in patients with metastatic cancer who suffer from severe and irreversible hepatic impairment: a single center experience.
    Hepato-gastroenterology, 2014, Volume: 61, Issue:135

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Deoxycytidine; Female; Gemcitabine; Humans; Liver Diseases; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Turkey

2014
Pharmacokinetics of gemcitabine at fixed-dose rate infusion in patients with normal and impaired hepatic function.
    Clinical pharmacokinetics, 2009, Volume: 48, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Area Under Curve; Biliary Tract Neoplasms; Chromatography, High Pressure Liquid; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Floxuridine; Gemcitabine; Humans; Infusions, Intravenous; Liver Diseases; Liver Function Tests; Male; Middle Aged; Pancreatic Neoplasms; Prospective Studies; Tandem Mass Spectrometry

2009
Accumulation of lipid peroxidation-derived DNA lesions in iron-overloaded thalassemic mouse livers: comparison with levels in the lymphocytes of thalassemia patients.
    International journal of cancer, 2009, Aug-15, Volume: 125, Issue:4

    Topics: Adolescent; Adult; Animals; beta-Globins; beta-Thalassemia; Case-Control Studies; Child; Deoxyadenosines; Deoxycytidine; DNA Adducts; DNA Damage; Glutathione Peroxidase; Humans; Immunoenzyme Techniques; Iron Overload; Lipid Peroxidation; Liver Diseases; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Oxidative Stress; Reactive Oxygen Species; Young Adult

2009
Placement of an expandable metallic stent improves the efficacy of chemoradiotherapy for pancreatic cancer with malignant portal vein stenosis or obstruction.
    Anticancer research, 2009, Volume: 29, Issue:8

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Constriction, Pathologic; Cyclophosphamide; Deoxycytidine; Female; Gemcitabine; Humans; Hypertension, Portal; Liver Diseases; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Pancreatic Neoplasms; Prognosis; Radiotherapy Dosage; Stents; Survival Rate; Tegafur; Treatment Outcome; Uracil

2009
Toxicities of gemcitabine in patients with severe hepatic dysfunction.
    The Annals of pharmacotherapy, 2010, Volume: 44, Issue:4

    Topics: Alanine Transaminase; Antimetabolites, Antineoplastic; Aspartate Aminotransferases; Bilirubin; Breast Neoplasms; Deoxycytidine; Female; Gemcitabine; Humans; Leukocyte Count; Liver Diseases; Male; Neoplasms; Pancreatic Neoplasms; Platelet Count; Retrospective Studies

2010
[Hodgkin lymphoma with hepatic involvement treated with dexametasone, gemcitabine and cisplatin as a bridge to standard therapy: report of one case].
    Revista medica de Chile, 2012, Volume: 140, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Dexamethasone; Female; Gemcitabine; Hodgkin Disease; Humans; Liver Diseases; Middle Aged; Salvage Therapy

2012
Labeling changes for tenofovir.
    AIDS patient care and STDs, 2004, Volume: 18, Issue:1

    Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Drug Interactions; Drug Labeling; Drug Therapy, Combination; Emtricitabine; Humans; Liver Diseases; Organophosphonates; Organophosphorus Compounds; Tenofovir

2004
Capecitabine as salvage therapy for a pancreatic cancer patient with extensive liver metastases and associated impairment of liver function.
    JOP : Journal of the pancreas, 2008, May-08, Volume: 9, Issue:3

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Disease Progression; Fluorouracil; Humans; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Salvage Therapy

2008
Effect of hepatic dysfunction due to liver metastases on the pharmacokinetics of capecitabine and its metabolites.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Breast Neoplasms; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Female; Fluorouracil; Humans; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis

1999