deoxycytidine and Leukemia L 1210

deoxycytidine has been researched along with Leukemia L 1210 in 71 studies

Research

Studies (71)

Timeframe	Studies, this research(%)	All Research%
pre-1990	49 (69.01)	18.7374
1990's	17 (23.94)	18.2507
2000's	4 (5.63)	29.6817
2010's	1 (1.41)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cook, PD; McNamara, DJ	1
Bloomer, LC; Patil, VD; Townsend, LB; Wise, DS; Wotring, LL	1
Avery, TL; Chwang, TL; Fridland, A	1
Baze, WB; Cui, Z; Finch, RA; Jolly, CA; Naguib, YW; Valdes, S	1
Arias, JL; Couvreur, P; Reddy, LH	1
Cros, E; Dumontet, C; Galmarini, CM; Gouy, MH; Jordheim, LP; Mackey, J; Perigaud, C; Peyrottes, S	1
Cory, AH; Cory, JG	1
Couvreur, P; Desmaele, D; Dubernet, C; Marque, PE; Mouelhi, SL; Reddy, LH	1
Durkacz, BW; Gray, DA; Shall, S	1
Balzarini, J; De Clercq, E; Duggan, MJ; Dyer, RL; Jones, AS; Rahim, SG; Walker, RT	1
Balzarini, J; De Clercq, E	3
Bacon, PE; Chiba, P; Cory, JG	1
Balzarini, J; Buchele, A; De Clercq, E; Keppeler, K; Kiefer, G	1
Boothman, DA; Greer, S; Mekras, JA; Perez, LM	1
Covey, JM; Zaharko, DS	1
Samuels, LL; Straw, JA	1
Cory, JG; Montgomery, JA; Sato, A	1
Lin, TS; Mancini, WR	1
Gao, YS; Lin, TS; Mancini, WR	1
Balzarini, J; De Clercq, E; Hunston, RN; Jones, AS; McGuigan, C; Walker, RT	1
Cysyk, RL; Hoerauf, RM; Karle, JM	1
Ramonas, LM; Zaharko, DS	1
Braun, TJ; Burchenal, JH; Chou, TC; Fox, JJ; Philips, FS; Schmid, FA; Su, TL; Watanabe, KA	1
Katz, DJ; Townsend, LB; Wise, DS	1
Balzarini, J; Bergstrom, DE; De Clercq, E; Descamps, J; Huang, GF; Jones, AS; Serafinowski, P; Torrence, PF; Verhelst, G; Walker, RT	1
Cadman, E; Grant, S; Lehman, C	1
Kalman, TI; Kerr, SG	1
Dan, A; Matsuda, A; Minakawa, N; Okazaki, S; Sasaki, T; Sugimoto, Y; Tregear, SJ	1
Cory, AH; Cory, JG; Robins, MJ; Samano, V	1
Cory, AH; Cory, JG; Hertel, LW; Kroin, JS	1
Chalovich, JM; Cory, AH; Cory, JG; Shibley, IA	1
Tsukagoshi, S	1
Cory, AH; Cory, JG; Nelson, TO; Somerville, L	1
Gowans, B; Hunting, DJ; Tremblay, S; Wagner, JR	1
Marańda, E; Robak, T	1
Bergman, AM; Brouwer, M; Eriksson, S; Jongsma, AP; Leyva, A; Peters, GJ; Pinedo, HM; Ruiz van Haperen, VW; Veerman, G	1
Marañda, E; Robak, T; Szmigielska, A	1
Schreiber, C; Waxman, S	1
Buchman, VM; Lichinitser, MR; Mkheidze, DM; Svet-Moldavsky, GJ	1
Abbasi, MM; Beisler, JA; Voytek, P; Wolpert-DeFilippes, MK	1
Cihák, A; Veselý, J	1
Gonzales, FA; Momparier, RL	1
Brockman, RW; Nelson, JA; Rose, LM; Schabel, FM; Shaddix, SC; Williams, M	1
Bukhman, VM; Lichinitser, MR; Mkheidze, DM; Svet-Moldavskiĭ, GIa	1
Momparler, LF; Momparler, RL; Rivard, GE; Veselý, J	1
Barkhotkina, MF; Belyanchikova, NI; Buchman, VM; Lichinitser, MR; Litovchenko, TA; Mkheidze, DM; Svet-Moldavsky, GJ	1
Buchman, VM; Lichinitser, MR; Mkheidze, DM; Svet-Maoldavsky, GJ	1
Baguley, BC; Falkenhaug, EM	1
Chou, TC; Hutchison, DJ; Philips, FS; Schmid, FA	1
Harrap, KR; Mulder, JH	1
Mancini, WR	1
Montgomery, JA; Riordan, JM; Secrist, JA; Tiwari, KN	1
Birnbaum, GI; Cheng, YC; Clarke-Katzenburg, RH; Gabe, EJ; Giziewicz, J; Lin, TS; Liu, MC; Luo, MZ; Mancini, WR; Prusoff, WH	1
Matsuda, A; Sasaki, T; Takenuki, K; Ueda, T	1
Matsuda, A; Sasaki, T; Takenuki, K; Tanaka, M; Ueda, T	1
Boder, GB; Grindey, GB; Hertel, LW; Kroin, JS; Poore, GA; Rinzel, SM; Todd, GC	1
Veselý, J	1
Balzarini, J; Broder, S; Cooney, DA; Cupp, JE; Dalal, M; DeClercq, E; Johns, DG; Kang, GJ	1
Danenberg, PV; Ibric, LL; Peterson, AR; Peterson, H	1
Kalman, TI; Yalowich, JC	1
Itoh, H; Matsuda, A; Sasaki, T; Takenuki, K; Ueda, T	1
Cory, JG; Weckbecker, G	1
Bergstrom, D; Kahilainen, L; Kangas, L; Vilpo, JA	1
Lin, TS; Prusoff, WH	1
Cory, JG; Ohmstede, CA	1
Balzarini, J	1
Jato, J; Windheuser, JJ	1
Bloch, A; McPartland, RP; Wang, MC; Weinfeld, H	1
Bloch, A; Sharma, RA; Wang, MC	1

Reviews

2 review(s) available for deoxycytidine and Leukemia L 1210

Article	Year
[Development of antimetabolites, II]. Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:1 Topics: Aminopterin; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cytarabine; Deoxycytidine; Humans; Leukemia L1210; Methotrexate; Mice; Trimetrexate	1993
Deoxyribonucleoside-induced selective modulation of cytotoxicity and mutagenesis. Basic life sciences, 1985, Volume: 31 Topics: Alkylating Agents; Animals; Azaguanine; Cell Line; Cell Survival; Cricetinae; Deoxyadenosines; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanosine; Deoxyribonucleosides; DNA; Drug Resistance; Drug Synergism; Floxuridine; Leukemia L1210; Lung; Methylation; Methylnitronitrosoguanidine; Mice; Mutagens; Mutation; Thymidine; Thymidylate Synthase; Thymine Nucleotides	1985

Article

Year

[Development of antimetabolites, II].

Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:1

Topics: Aminopterin; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cytarabine; Deoxycytidine; Humans; Leukemia L1210; Methotrexate; Mice; Trimetrexate

1993

Deoxyribonucleoside-induced selective modulation of cytotoxicity and mutagenesis.

Basic life sciences, 1985, Volume: 31

Topics: Alkylating Agents; Animals; Azaguanine; Cell Line; Cell Survival; Cricetinae; Deoxyadenosines; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanosine; Deoxyribonucleosides; DNA; Drug Resistance; Drug Synergism; Floxuridine; Leukemia L1210; Lung; Methylation; Methylnitronitrosoguanidine; Mice; Mutagens; Mutation; Thymidine; Thymidylate Synthase; Thymine Nucleotides

1985

Other Studies

69 other study(ies) available for deoxycytidine and Leukemia L 1210

Article	Year
Synthesis and antitumor activity of fluorine-substituted 4-amino-2(1H)-pyridinones and their nucleosides. 3-Deazacytosines. Journal of medicinal chemistry, 1987, Volume: 30, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Cytosine; Drug Evaluation, Preclinical; Indicators and Reagents; Leukemia L1210; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Spectrophotometry; Structure-Activity Relationship	1987
Synthesis and biological activity of a novel adenosine analogue, 3-beta-D-ribofuranosylthieno[2,3-d]pyrimidin-4-one. Journal of medicinal chemistry, 1985, Volume: 28, Issue:4 Topics: Adenosine; Adenosine Kinase; Animals; Antineoplastic Agents; Biotransformation; In Vitro Techniques; Leukemia L1210; Mice; Pyrimidine Nucleosides	1985
2'-O-nitro-1-beta-D-arabinofuranosylcytosine. A new derivative of 1-beta-D-arabinofuranosylcytosine that resists enzymatic deamination and has antileukemic activity. Journal of medicinal chemistry, 1983, Volume: 26, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; Drug Evaluation, Preclinical; Female; Leukemia L1210; Mice; Mice, Inbred Strains	1983
Preclinical Evaluation of the Short-Term Toxicity of 4-(N)-Docosahexaenoyl 2´, 2´- Difluorodeoxycytidine (DHA-dFdC). Pharmaceutical research, 2017, Volume: 34, Issue:6 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Deoxycytidine; Drug Compounding; Female; Gemcitabine; Humans; Leukemia L1210; Maximum Tolerated Dose; Mice, Inbred DBA	2017
Polymeric nanoparticulate system augmented the anticancer therapeutic efficacy of gemcitabine. Journal of drug targeting, 2009, Volume: 17, Issue:8 Topics: Animals; Antimetabolites, Antineoplastic; Cyanoacrylates; Deoxycytidine; Drug Carriers; Gemcitabine; Hydrogen-Ion Concentration; Injections, Intravenous; Leukemia L1210; Mice; Mice, Inbred DBA; Nanoparticles; Polymers	2009
Characterization of a gemcitabine-resistant murine leukemic cell line: reversion of in vitro resistance by a mononucleotide prodrug. Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Aug-15, Volume: 10, Issue:16 Topics: Animals; Antimetabolites, Antineoplastic; Base Sequence; Cell Survival; Deoxycytidine; Disease Models, Animal; DNA Primers; Drug Resistance, Neoplasm; Gemcitabine; Gene Expression Regulation, Neoplastic; Kinetics; Leukemia L1210; Mice; Polymerase Chain Reaction; Time Factors	2004
Gemcitabine-induced apoptosis in a drug-resistant mouse leukemia L1210 cell line that does not express p53. Advances in enzyme regulation, 2004, Volume: 44 Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Cycle; Cell Division; Cell Line, Tumor; Deoxyadenosines; Deoxycytidine; Drug Resistance, Neoplasm; Flavonoids; Gemcitabine; Leukemia L1210; Methotrexate; Mice; Piperidines; Tumor Suppressor Protein p53	2004
A new nanomedicine of gemcitabine displays enhanced anticancer activity in sensitive and resistant leukemia types. Journal of controlled release : official journal of the Controlled Release Society, 2007, Dec-04, Volume: 124, Issue:1-2 Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Resistance, Neoplasm; Humans; Leukemia L1210; Mice; Mice, Inbred DBA; Molecular Structure; Nanomedicine; Nanoparticles; Squalene; Tissue Distribution	2007
Inhibitors of nuclear ADP-ribosyl transferase retard DNA repair after N-methyl-N-nitroso-urea. Further evidence for the involvement of (ADP-ribose)n in DNA repair. FEBS letters, 1981, Aug-17, Volume: 131, Issue:1 Topics: Adenosine Diphosphate Ribose; Animals; Cell Division; Centrifugation, Density Gradient; Deoxycytidine; DNA Repair; Leukemia L1210; Methylnitrosourea; Mice; Niacinamide; Nitrosourea Compounds; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Thymidine	1981
Synthesis and biological properties of 2'-deoxy-5-vinyluridine and 2'deoxy-5-vinylcytidine. Nucleic acids research, 1982, Sep-11, Volume: 10, Issue:17 Topics: Animals; Antiviral Agents; Deoxycytidine; Deoxyuridine; Drug Evaluation, Preclinical; Herpesviridae Infections; Leukemia L1210; Mice; Structure-Activity Relationship	1982
Role of deoxycytidine kinase in the inhibitory activity of 5-substituted 2'-deoxycytidines and cytosine arabinosides on tumor cell growth. Molecular pharmacology, 1983, Volume: 23, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Bromodeoxyuridine; Cell Division; Cytarabine; Deoxycytidine; Deoxycytidine Kinase; DNA, Neoplasm; Leukemia L1210; Mice; Phosphotransferases; Thymidine Kinase	1983
Studies directed toward testing the "channeling" hypothesis--ribonucleotides----DNA in leukemia L1210 cells. Biochemical and biophysical research communications, 1984, Sep-17, Volume: 123, Issue:2 Topics: Animals; Aphidicolin; Cytidine; Deoxycytidine; Diterpenes; DNA Replication; Hydroxyurea; Leukemia L1210; Mice; Multienzyme Complexes; Nucleic Acid Synthesis Inhibitors; Ribonucleotide Reductases; Ribonucleotides; Thymidylate Synthase	1984
Antitumor cell and antimetabolic effects of 5-ethyl-2'-deoxyuridine and 5'-substituted 5-ethyl-2'-deoxyuridine derivatives. Investigational new drugs, 1984, Volume: 2, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Cell Division; Cell Survival; Cells, Cultured; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Leukemia L1210; Mice; Thymidine Kinase	1984
Use of 5-fluorodeoxycytidine and tetrahydrouridine to exploit high levels of deoxycytidylate deaminase in tumors to achieve DNA- and target-directed therapies. Cancer research, 1984, Volume: 44, Issue:6 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich Tumor; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Cricetinae; Cricetulus; DCMP Deaminase; Deoxycytidine; DNA Replication; Drug Evaluation, Preclinical; Female; Humans; Leukemia L1210; Leukemia, Experimental; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Nucleotide Deaminases; Ovary; Tetrahydrouridine; Uridine	1984
Modulation of deoxycytidine metabolism in vivo with high-dose thymidine in mice. Journal of the National Cancer Institute, 1983, Volume: 71, Issue:5 Topics: Animals; Bone Marrow; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Deoxycytidine; DNA, Neoplasm; Duodenum; Half-Life; Kinetics; Leukemia L1210; Mice; Mice, Inbred Strains; Spleen; Thymidine	1983
Improved therapeutic index with high-dose methotrexate: comparison of thymidine-purine rescue with citrovorum factor rescue in mice. Cancer research, 1984, Volume: 44, Issue:6 Topics: Animals; Brain Neoplasms; Deoxycytidine; DNA Replication; Dose-Response Relationship, Drug; Hypoxanthine; Hypoxanthines; Inosine; Leucovorin; Leukemia L1210; Methotrexate; Mice; Thymidine; Thymine	1984
Synergistic inhibition of leukemia L1210 cell growth in vitro by combinations of 2-fluoroadenine nucleosides and hydroxyurea or 2,3-dihydro-1H-pyrazole[2,3-a]imidazole. Cancer research, 1984, Volume: 44, Issue:8 Topics: Animals; Cell Survival; Cytidine; Deferoxamine; Deoxyadenosines; Deoxycytidine; Drug Synergism; Hydroxyurea; Kinetics; Leukemia L1210; Mice; Pyrazoles; Vidarabine	1984
Ribo- and deoxyribonucleoside effect on 3'-amino-2',3'-dideoxycytidine-induced cytotoxicity in cultured L1210 cells. Biochemical pharmacology, 1983, Aug-15, Volume: 32, Issue:16 Topics: Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Cytarabine; Deamination; Deoxycytidine; Deoxyribonucleosides; DNA, Neoplasm; Leukemia L1210; Ribonucleosides; Zalcitabine	1983
Synthesis and biological activity of various 3'-azido and 3'-amino analogues of 5-substituted pyrimidine deoxyribonucleosides. Journal of medicinal chemistry, 1983, Volume: 26, Issue:12 Topics: Animals; Antineoplastic Agents; Deoxycytidine; Deoxycytidine Kinase; Deoxyuridine; Leukemia L1210; Mice; Sarcoma 180; Thymidine Kinase	1983
Strategies for the measurement of the inhibitory effects of thymidine analogs on the activity of thymidylate synthase in intact murine leukemia L1210 cells. Biochimica et biophysica acta, 1984, Feb-28, Volume: 785, Issue:1-2 Topics: Animals; Deoxycytidine; Deoxyuridine; DNA; Leukemia L1210; Methyltransferases; Mice; Thymidine; Thymidylate Synthase	1984
Synthesis and biological properties of some cyclic phosphotriesters derived from 2'-deoxy-5-fluorouridine. Journal of medicinal chemistry, 1984, Volume: 27, Issue:4 Topics: Animals; Antimetabolites, Antineoplastic; Bromodeoxyuridine; Deoxycytidine; Deoxyuridine; Drug Resistance; Indicators and Reagents; Leukemia L1210; Mice; Organophosphorus Compounds; Structure-Activity Relationship; Thymidine; Thymidine Monophosphate	1984
Labelling of the thymidine and deoxycytidine bases of DNA by [2-14C]deoxycytidine in cultured L1210 cells. Cancer letters, 1983, Volume: 19, Issue:2 Topics: 3-Deazauridine; Animals; Carbon Radioisotopes; Cytarabine; Cytidine; Deoxycytidine; DNA; Leukemia L1210; Mice; Tetrahydrouridine; Thymidine	1983
Comparison of in vitro and in vivo effects of thymidine on L1210 leukemia in mice. Journal of the National Cancer Institute, 1982, Volume: 68, Issue:5 Topics: Animals; Cell Survival; Chromatography, High Pressure Liquid; Clone Cells; Deoxycytidine; Dose-Response Relationship, Drug; Leukemia L1210; Mice; Mice, Inbred BALB C; Spleen; Thymidine; Time Factors	1982
Biochemical effects of 2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil and 2'-fluoro-5-iodo-1-beta-D-arabinofuranosylcytosine in mouse leukemic cells sensitive and resistant to 1-beta-D-arabinofuranosylcytosine. Cancer research, 1982, Volume: 42, Issue:10 Topics: Animals; Arabinofuranosyluracil; Cell Survival; Cytarabine; Deoxycytidine; DNA Replication; Kinetics; Leukemia L1210; Leukemia, Experimental; Mice; Thymidine; Uridine	1982
Synthesis of pyridazine analogues of the naturally occurring nucleosides cytidine, uridine, deoxycytidine, and deoxyuridine. Journal of medicinal chemistry, 1982, Volume: 25, Issue:7 Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Cytidine; Deoxycytidine; Deoxyuridine; Hydrolysis; In Vitro Techniques; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Pyridazines; Pyrimidine Nucleosides; Uridine	1982
Antiviral, antimetabolic, and cytotoxic activities of 5-substituted 2'-deoxycytidines. Molecular pharmacology, 1982, Volume: 21, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Deoxycytidine; DNA, Neoplasm; Leukemia L1210; Mice; Time Factors	1982
Enhancement of 1-beta-D-arabinofuranosylcytosine accumulation within L1210 cells and increased cytotoxicity following thymidine exposure. Cancer research, 1980, Volume: 40, Issue:5 Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cytarabine; Deoxycytidine; Deoxyribonucleotides; DNA, Neoplasm; Leukemia L1210; Mice; RNA, Neoplasm; Thymidine; Time Factors	1980
N4-(dialkylamino)methylene derivatives of 2'-deoxycytidine and arabinocytidine: physicochemical studies for potential prodrug applications. Journal of pharmaceutical sciences, 1994, Volume: 83, Issue:4 Topics: Animals; Chemical Phenomena; Chemistry, Physical; Cytarabine; Deoxycytidine; Drug Stability; Half-Life; Hydrolysis; Kinetics; Leukemia L1210; Lipids; Mice; Prodrugs; Solubility	1994
Nucleosides and nucleotides. 123. Synthesis of 1-(2-deoxy-2-isocyano-beta-D-arabinofuranosyl)cytosine and related nucleosides as potential antitumor agents. Journal of medicinal chemistry, 1993, Dec-24, Volume: 36, Issue:26 Topics: Animals; Antineoplastic Agents; Cytarabine; Deoxycytidine; Drug Stability; Humans; Isocyanates; Leukemia L1210; Lung Neoplasms; Mice; Molecular Structure; Mouth Neoplasms; Stomach Neoplasms; Thymine; Tumor Cells, Cultured; Uracil	1993
2'-Deoxy-2'-methylene derivatives of adenosine, guanosine, tubercidin, cytidine and uridine as inhibitors of L1210 cell growth in culture. Biochemical pharmacology, 1994, Jan-20, Volume: 47, Issue:2 Topics: Animals; Cell Cycle; Cell Division; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyuridine; Leukemia L1210; Ribonucleotide Reductases; Tubercidin; Tumor Cells, Cultured	1994
Effects of 2',2'-difluorodeoxycytidine (Gemcitabine) on wild type and variant mouse leukemia L1210 cells. Oncology research, 1993, Volume: 5, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Carbon Radioisotopes; Cytidine; Deoxycytidine; Gemcitabine; Leukemia L1210; Mice; Ribonucleotide Reductases; Tumor Cells, Cultured	1993
Deoxyguanosine-resistant leukemia L1210 cells. Loss of specific deoxyribonucleoside kinase activity. The Journal of biological chemistry, 1993, Jan-05, Volume: 268, Issue:1 Topics: Animals; Antineoplastic Agents; Cell Division; Cytarabine; Deoxycytidine; Deoxyguanosine; Drug Resistance; Kinetics; Leukemia L1210; Mice; Nucleosides; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Tumor Cells, Cultured	1993
Alterations in the properties of mouse leukemia L1210 cell lines selected by different methods for resistance to deoxyguanosine. Advances in enzyme regulation, 1997, Volume: 37 Topics: Animals; Cell Division; Cladribine; Cytarabine; Deoxycytidine; Deoxycytidine Kinase; Deoxyguanosine; Drug Resistance, Neoplasm; Kinetics; Leukemia L1210; Mice; Phosphotransferases (Alcohol Group Acceptor); Tumor Cells, Cultured	1997
Incorporation of two deoxycytidine oxidation products into cellular DNA. Biochemistry and cell biology = Biochimie et biologie cellulaire, 1997, Volume: 75, Issue:4 Topics: Animals; Deoxycytidine; Deoxyuridine; DNA; DNA Damage; DNA Repair; HeLa Cells; Humans; Jurkat Cells; Leukemia L1210; Mice; Oxidation-Reduction	1997
Interactions of 2',2'-diflurodeoxycytidine (gemcitabine) with tumor necrosis factor alpha or its mutein VI in murine leukemias L1210 and P388. Archivum immunologiae et therapiae experimentalis, 1998, Volume: 46, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Deoxycytidine; Drug Interactions; Gemcitabine; Leukemia L1210; Leukemia P388; Male; Mice; Tumor Necrosis Factor-alpha	1998
Decreased resistance to gemcitabine (2',2'-difluorodeoxycitidine) of cytosine arabinoside-resistant myeloblastic murine and rat leukemia cell lines: role of altered activity and substrate specificity of deoxycytidine kinase. Biochemical pharmacology, 1999, Feb-15, Volume: 57, Issue:4 Topics: Animals; Antimetabolites, Antineoplastic; Cell Division; Cytarabine; Cytidine Deaminase; Deoxycytidine; Deoxycytidine Kinase; DNA; Drug Resistance; Gemcitabine; Leukemia L1210; Mice; Nucleoside Deaminases; Polyphosphates; Rats; Rats, Inbred BN; Substrate Specificity; Thymidine Kinase; Tumor Cells, Cultured	1999
Additive action of gemcitabine (2',2'-difluorodeoxycytidine) and 2-chlorodeoxyadenosine on murine leukemias L1210 and P388. Cancer investigation, 1999, Volume: 17, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Deoxycytidine; Drug Administration Schedule; Drug Screening Assays, Antitumor; Drug Synergism; Gemcitabine; Leukemia L1210; Leukemia P388; Male; Mice	1999
Varying effects of deoxynucleosides on the incorporation of thymidine into the DNA of monolayer and suspension cultures. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1977, Volume: 154, Issue:4 Topics: Animals; Ascites; Bone Marrow; Bone Marrow Cells; Cell Survival; Cells, Cultured; Deoxycytidine; Deoxyuridine; DNA; HeLa Cells; Hydrogen-Ion Concentration; Leukemia L1210; Lymphocytes; Neoplasms, Experimental; Thymidine	1977
Deoxycytidine and lethal doses of cytarabine in advanced murine leukaemia. Lancet (London, England), 1977, May-14, Volume: 1, Issue:8020 Topics: Administration, Oral; Animals; Cytarabine; Deoxycytidine; Drug Antagonism; Drug Therapy, Combination; Female; Injections, Intraperitoneal; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mice	1977
Comparative studies of the cytostatic action and metabolism of 5-azacytidine and 5,6-dihydro-5-azacytidine. Cancer research, 1977, Volume: 37, Issue:7 Pt 1 Topics: Animals; Azacitidine; Cell Division; Cells, Cultured; Cytidine; Cytidine Deaminase; Deoxycytidine; Drug Synergism; Kinetics; Leukemia L1210; Oxidative Phosphorylation; Tetrahydrouridine; Thymidine; Uridine	1977
Incorporation of a potent antileukemic agent, 5-aza-2'-deoxycytidine, into DNA of cells from leukemic mice. Cancer research, 1977, Volume: 37, Issue:10 Topics: Animals; Azacitidine; Deoxycytidine; Epithelium; Female; Leukemia L1210; Leukemia, Experimental; Liver; Lymph Nodes; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred DBA; Precancerous Conditions; Thymidine	1977
Effect of intravenous infusion of 5-aza-2'-deoxycytidine on survival time of mice with L1210 leukemia. Cancer research, 1978, Volume: 38, Issue:9 Topics: Animals; Azacitidine; Cell Survival; Deoxycytidine; In Vitro Techniques; Infusions, Parenteral; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Time Factors	1978
The mechanism of action of 3-deazauridine in tumor cells sensitive and resistant to arabinosylcytosine. Annals of the New York Academy of Sciences, 1975, Aug-08, Volume: 255 Topics: 3-Deazauridine; Adenocarcinoma; Animals; Cell Line; Cytarabine; Deoxycytidine; Deoxyribonucleotides; DNA, Neoplasm; Drug Resistance; Leukemia L1210; Liver; Mice; Neoplasms, Experimental; Orotic Acid; Phosphotransferases; Pyrimidine Nucleotides; Ribonucleotide Reductases; Ribonucleotides; RNA, Neoplasm; Uracil Nucleotides; Uridine	1975
[Selective treatment of leukemia L1210 with combination of deoxycytidine and lethal doses of cytosine arabinoside]. Biulleten' eksperimental'noi biologii i meditsiny, 1978, Volume: 85, Issue:3 Topics: Administration, Oral; Animals; Cytarabine; Deoxycytidine; Drug Evaluation; Drug Therapy, Combination; Injections, Intraperitoneal; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mice	1978
Synergistic action of 5-aza-2'-deoxycytidine and 3-deazauridine on L1210 leukemic cells and EMT6 tumor cells. Cancer research, 1979, Volume: 39, Issue:10 Topics: 3-Deazauridine; Animals; Cell Division; Cell Survival; Cells, Cultured; Deoxycytidine; DNA, Neoplasm; Drug Synergism; Leukemia L1210; Male; Mammary Neoplasms, Experimental; Mice; Uridine	1979
2'-Deoxycytidine hydrochloride protection of mice against the lethal toxicity of cytosine arabinoside. Absence of protection of bone marrow lymphocytes. Cancer chemotherapy and pharmacology, 1979, Volume: 3, Issue:4 Topics: Animals; Antibody Formation; Bone Marrow; Bone Marrow Cells; Cytarabine; Deoxycytidine; Female; Immunity, Cellular; Leukemia L1210; Lymphocytes; Male; Mice; Mice, Inbred Strains; Time Factors	1979
Selective chemotherapy for advanced murine L 1210 leukemia by combination of 2' deoxycytidine and lethal doses of cytosine-arabinoside. Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1977, Volume: 27, Issue:5 Topics: Animals; Cytarabine; Deoxycytidine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Leukemia L1210; Male; Mice	1977
Plasma half-life of cytosine arabinoside in patients with leukaemia--the effect of uridine. European journal of cancer, 1975, Volume: 11, Issue:1 Topics: Administration, Oral; Aminohydrolases; Animals; Cell Count; Cytarabine; Deoxycytidine; DNA, Neoplasm; Dose-Response Relationship, Drug; Half-Life; Humans; Leukemia L1210; Leukemia, Myeloid; Leukocytes; Mice; Uridine	1975
Occurrence of deaminated monophosphate nucleotide in extracellular sites after giving arabinofuranosylcytosine or deoxycytidine to mice. Annals of the New York Academy of Sciences, 1975, Aug-08, Volume: 255 Topics: Animals; Blood Platelets; Cytarabine; Deoxycytidine; Intestine, Small; Leukemia L1210; Leukocytes; Liver; Mice; Myocardium; Nucleosides; Nucleotides; Spleen; Thymus Gland	1975
Cytosine arabinoside uptake by tumour cells in vitro. European journal of cancer, 1975, Volume: 11, Issue:5 Topics: Animals; Cytarabine; Deoxycytidine; Diffusion; Female; In Vitro Techniques; Kinetics; Leukemia L1210; Leukemia, Experimental; Neoplasms, Experimental; Rats; Sarcoma, Yoshida	1975
The role of deoxycytidine-metabolizing enzymes in the cytotoxicity induced by 3'-amino-2',3'-dideoxycytidine and cytosine arabinoside. Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:2 Topics: Animals; Antineoplastic Agents; Cell Count; Cell Division; Cytarabine; Cytidine Deaminase; Deoxycytidine; HeLa Cells; Humans; Leukemia L1210; Mice; Nucleoside Deaminases; Sensitivity and Specificity; Tumor Cells, Cultured; Zalcitabine	1992
Synthesis and biological activity of 2'-deoxy-4'-thio pyrimidine nucleosides. Journal of medicinal chemistry, 1991, Volume: 34, Issue:8 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Cytomegalovirus; Deoxycytidine; Deoxyuridine; Humans; Leukemia L1210; Leukemia, T-Cell; Mice; Simplexvirus; Thionucleosides; Thiouridine; Thymidine; Tumor Cells, Cultured	1991
Synthesis and anticancer and antiviral activities of various 2'- and 3'-methylidene-substituted nucleoside analogues and crystal structure of 2'-deoxy-2'-methylidenecytidine hydrochloride. Journal of medicinal chemistry, 1991, Volume: 34, Issue:8 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Chemical Phenomena; Chemistry; Crystallization; Cytarabine; Deoxycytidine; Female; Humans; Leukemia L1210; Leukemia P388; Leukemia, Lymphoid; Mice; Molecular Structure; Nucleosides; Sarcoma 180; Simplexvirus; Tumor Cells, Cultured; X-Ray Diffraction	1991
Nucleosides and nucleotides. 94. Radical deoxygenation of tert-alcohols in 1-(2-C-alkylpentofuranosyl) pyrimidines: synthesis of (2'S)-2'-deoxy-2'-C-methylcytidine, an antileukemic nucleoside. Journal of medicinal chemistry, 1991, Volume: 34, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Deoxycytidine; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Leukemia; Leukemia L1210; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Molecular Structure; Neoplasms; Structure-Activity Relationship	1991
Nucleosides and nucleotides. 97. Synthesis of new broad spectrum antineoplastic nucleosides, 2'-deoxy-2'-methylidenecytidine (DMDC) and its derivatives. Journal of medicinal chemistry, 1991, Volume: 34, Issue:2 Topics: Animals; Antineoplastic Agents; Cells, Cultured; Chemical Phenomena; Chemistry; Deoxycytidine; Female; Humans; Leukemia L1210; Mice; Structure-Activity Relationship	1991
Evaluation of the antitumor activity of gemcitabine (2',2'-difluoro-2'-deoxycytidine). Cancer research, 1990, Jul-15, Volume: 50, Issue:14 Topics: Animals; Antimetabolites, Antineoplastic; Cell Line; Cell Survival; Deoxycytidine; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Female; Flow Cytometry; Gemcitabine; Humans; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Neoplasms, Experimental; Tumor Cells, Cultured	1990
High degree of resistance to 5-aza-2'-deoxycytidine in L1210 cells in vitro associated with almost complete loss of deoxycytidine kinase activity. Neoplasma, 1987, Volume: 34, Issue:6 Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cells, Cultured; Cytosine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; DNA (Cytosine-5-)-Methyltransferases; Drug Resistance; Leukemia L1210; Mice; Phosphorylation; Phosphotransferases	1987
Differential affinities of pyrimidine nucleoside analogues for deoxythymidine and deoxycytidine kinase determine their incorporation into murine leukemia L1210 cells. Acta biochimica Polonica, 1987, Volume: 34, Issue:2 Topics: Animals; Cells, Cultured; Deoxycytidine; Deoxycytidine Kinase; Leukemia L1210; Mice; Nucleic Acids; Phosphotransferases; Pyrimidine Nucleosides; Thymidine; Thymidine Kinase	1987
2',3'-Dideoxycytidine: regulation of its metabolism and anti-retroviral potency by natural pyrimidine nucleosides and by inhibitors of pyrimidine nucleotide synthesis. Molecular pharmacology, 1987, Volume: 32, Issue:6 Topics: Animals; Antiviral Agents; Deoxycytidine; Deoxycytosine Nucleotides; HIV; Humans; Leukemia L1210; Mice; Phosphorylation; Pyrimidine Nucleosides; Pyrimidine Nucleotides; Pyrimidines; Thymidine; Tritium; Tumor Cells, Cultured; Zalcitabine	1987
Rapid determination of thymidylate synthase activity and its inhibition in intact L1210 leukemia cells in vitro. Biochemical pharmacology, 1985, Jul-01, Volume: 34, Issue:13 Topics: Animals; Cells, Cultured; Deoxycytidine; Deoxyuridine; Dose-Response Relationship, Drug; Floxuridine; Leukemia L1210; Methotrexate; Methyltransferases; Mice; Thymidylate Synthase; Tritium	1985
Radical deoxygenation of tert-alcohols in 2'-branched-chain sugar pyrimidine nucleosides: synthesis and antileukemic activity of 2'-deoxy-2' (S)-methylcytidine. Chemical & pharmaceutical bulletin, 1987, Volume: 35, Issue:9 Topics: Alcohols; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Deoxycytidine; Leukemia L1210; Mice; Tumor Cells, Cultured	1987
2,6-Diaminopurinedeoxyriboside as a prodrug of deoxyguanosine in L1210 cells. Cancer research, 1987, May-01, Volume: 47, Issue:9 Topics: 2-Aminopurine; Adenosine Deaminase Inhibitors; Animals; Cell Division; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA Replication; Dose-Response Relationship, Drug; Leukemia L1210; Ribonucleotide Reductases	1987
In vitro and in vivo studies of a promising antileukemic thymidine analogue, 5-hydroxymethyl-2' deoxyuridine. Biochemical pharmacology, 1986, Dec-01, Volume: 35, Issue:23 Topics: Animals; Antineoplastic Agents; Blood Platelets; Cell Line; Deoxycytidine; Humans; Leukemia; Leukemia L1210; Thymidine	1986
Enhancement of the anticancer activity of bis(2-chloroethyl)nitrosourea in mice by coadministration of 2'-deoxyuridine, 2'-deoxycytidine, or thymidine. Cancer research, 1987, Jan-15, Volume: 47, Issue:2 Topics: Animals; Carmustine; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Drug Synergism; Leukemia L1210; Melanoma, Experimental; Mice; Ribonucleosides; Thymidine	1987
Effect of the dialdehyde derivative of 5'-deoxyinosine on pyrimidine deoxyribonucleoside metabolism in L1210 cells. Biochemical pharmacology, 1985, May-15, Volume: 34, Issue:10 Topics: Animals; Cells, Cultured; DCMP Deaminase; Deoxycytidine; Deoxyuridine; Inosine; Leukemia L1210; Mice; Thymidylate Synthase	1985
Role of thymidylate synthetase in the cytostatic activity of pyrimidine nucleoside analogues. Bulletin et memoires de l'Academie royale de medecine de Belgique, 1985, Volume: 140, Issue:11 Topics: Animals; Antineoplastic Agents; Arabinofuranosyluracil; Cytarabine; Deoxycytidine; Deoxyuridine; Leukemia L1210; Mice; Pyrimidine Nucleosides; Thymidylate Synthase	1985
5-Fluorouracil and derivatives in cancer chemotherapy. 3. In vivo enhancement of antitumor activity of 5-fluorouracil (FU) and 5-fluoro-2'-deoxyuridine (FUDR). Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:12 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Chromatography, Thin Layer; Deoxycytidine; Deoxyuridine; Dialysis; Drug Synergism; Drug Therapy, Combination; Floxuridine; Fluorouracil; Leukemia L1210; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Homologous	1973
Cytidine 5'-triphosphate synthetase as a target for inhibition by the antitumor agent 3-deazauridine. Cancer research, 1974, Volume: 34, Issue:11 Topics: Animals; Cells, Cultured; Cytidine; Cytosine Nucleotides; Deoxycytidine; Deoxyuridine; Enzyme Inhibitors; Leukemia L1210; Ligases; Liver; Mice; Thymidine; Uracil Nucleotides; Uridine	1974
Studies on the mode of action of 2,2'-anhydro-1- -D-arabinofuranosylcytosine. Cancer research, 1973, Volume: 33, Issue:6 Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell-Free System; Chromatography, Paper; Cytarabine; Deamination; Deoxycytidine; Drug Resistance; Electrophoresis, Paper; Escherichia coli; Female; Hydrogen-Ion Concentration; Hydrolysis; Leukemia L1210; Mice; Mice, Inbred Strains; Oxidative Phosphorylation	1973