deoxycytidine and Leucocythaemia

deoxycytidine has been researched along with Leucocythaemia in 68 studies

Research

Studies (68)

Timeframe	Studies, this research(%)	All Research%
pre-1990	25 (36.76)	18.7374
1990's	19 (27.94)	18.2507
2000's	18 (26.47)	29.6817
2010's	6 (8.82)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chen, C; Han, Z; Li, Y; Liu, G; Liu, J; van Zijl, PC; Zhang, J	1
Campbell, DO; Czernin, J; Herschman, HR; Laing, RE; Phelps, ME; Radu, CG; Satyamurthy, N; Walter, MA; Witte, ON	1
Adema, AD; Kathmann, I; Losekoot, N; Myhren, F; Peters, GJ; Sandvold, ML; Smid, K	1
Bourgaux, C; Couvreur, P; Desmaële, D; Lepêtre-Mouelhi, S; Pili, B; Reddy, LH	1
Cass, CE; Damaraju, VL; Karpinski, E; Mowles, D; Nowak, I; Robins, MJ; Smith, KM; Young, JD	1
Adema, AD; Honeywell, RJ; Losekoot, N; Myhren, F; Peters, GJ; Sandvold, ML; Smid, K; Verheul, HM	1
Fritzer-Szekeres, M; Golakoti, T; Graser, G; Jaeger, W; Krupitza, G; Madlener, S; Saiko, P; Schwarz, S; Somepalli, V; Szekeres, T	1
Ames, MM; Avramis, VI; Krailo, MD; Liu-Mares, W; Reaman, GH; Reid, JM; Safgren, SL; Seibel, NL; Steinherz, PG	1
Bacher, N; Hohla, F; Konwalinka, G; Mühlmann, O; Strasser-Wozak, E; Tiefenthaler, M; Wein, W	1
Bresters, D; Broekhuizen, AJ; Faircloth, GT; Jimeno, J; Kaaijk, P; Kaspers, GJ	1
BURCHENAL, JH; FOX, JJ; HEMPHILL, SC; HOLMBERG, EA; REPPERT, JA	1
CALABRESI, P; CREASEY, WA; PRUSOFF, H; WELCH, AD	1
DELAMORE, IW; PRUSOFF, WH	1
EVANS, JS; MENGEL, GD	1
Kolb, EA; Steinherz, PG	1
Bergman, AM; Breistøl, K; Comijn, EM; Fodstad, O; Hendriks, HR; Kuiper, CM; Myhren, F; Noordhuis, P; Peters, GJ; Sandvold, ML; Smid, K; Voorn, DA	1
Bergman, AM; Hendriks, HR; Kuiper, CM; Myhren, F; Peters, GJ; Sandvold, ML	1
Dexheimer, TS; Fellows, IM; Gleason-Guzman, M; Hurley, LH; Schwaebe, M; Vankayalapati, H; Whitten, JP	1
Bodo, J; Duraj, J; Rauko, P; Sedlak, J; Sulikova, M	1
Couvreur, P; Desmaële, D; Dubernet, C; Marque, PE; Mouelhi, SL; Reddy, LH	1
Adams, DJ; Giles, F; Jacobsen, TF; Myhren, F; Rizzieri, DA; Sandvold, ML	1
Jekunen, A; Vilpo, JA	1
Jones, SP; Sawyer, WH; Wiley, JS	1
Andreeff, M; Blumenreich, MS; Chou, TC; Clarkson, BD; Vale, K; Young, CW	1
Akman, SA; Bachur, NR; Ross, DD; Schrecker, AW	1
Fox, RM; Tattersall, MH; Tripp, EH	1
Arlin, Z; Fiori, L; Kreis, W; Leyland-Jones, BR; Yagoda, A	1
Chapman, AJ; Chubb, S; Gandhi, V; Hertel, LW; Huang, P; Mineishi, S; Nowak, BJ; Plunkett, W; Yang, Y	1
Csoka, K; Larsson, R; Liliemark, J; Nygren, P	1
Eriksson, S; Kierdaszuk, B; Krawiec, K; Munch-Petersen, B; Shugar, D	1
Aida, S; Ishida, N; Ishiwata, S; Itoh, K; Mizugaki, M; Yamaguchi, T	1
Hata, Y; Prajda, N; Weber, G	1
Baker, M; Bhalla, K; Grant, S	1
Wiley, JS	1
Huang, P; Iwasaki, H; Keating, MJ; Plunkett, W	1
Heinemann, V; Issels, RD; Schulz, L; Wilmanns, W	1
Dent, P; Grant, S; Kramer, LB; Povirk, LF; Saunders, AM; Vrana, JA; Zhang, XF	1
Cvitkovic, E; Faivre, S; Raymond, E; Woynarowski, JM	1
Inanami, O; Kuwabara, M; Matsuda, A; Nomura, Y; Takahashi, K	1
Bergman, AM; Kroep, JR; Peters, GJ; Pinedo, HM; Ruiz van Haperen, VW; van Moorsel, CJ; Veerman, G; Voorn, DA	1
Aresta, A; Liso, V; Palmisano, F; Specchia, G; Zambonin, CG	1
Cass, CE; Clarke, ML; Gourdeau, H; Jolivet, J; Lafrenière, RG; Lee, N; Mackey, JR; Mowles, D; Ouellet, F; Richard, A; Selner, M; Young, JD	1
Beauséjour, CM; Eliopoulos, N; Le, NL; Momparler, L; Momparler, RL	1
Gandhi, V; Krett, N; Nabhan, C; Rosen, S	1
Adams, DJ; Bass, AJ; Davis, P; DeCastro, CM; Foster, T; Gockerman, JP; Hurwitz, H; Jacobson, R; Laughlin, MJ; Moore, JO; Petros, WP; Rizzieri, DA; Rosner, GL	1
Adams, DJ; Bass, AJ; Davis, P; DeCastro, CM; Foster, T; Gockerman, JP; Hammett, E; Moore, JO; Payne, N; Rizzieri, DA; Rosner, GL	1
Chabner, BA; Coleman, CN; Drake, JC; Stoller, RG	1
Chu, MY; Fischer, GA; Hoovis, ML	1
Carson, DA; Kaye, J; Seegmiller, JE	1
Hirt, A; Wagner, HP	1
Arnér, ES; Eriksson, S; Spasokoukotskaja, T	1
Nakamura, T; Ueda, T	1
Du, M; Faucher, K; Grunewald, R; Kantarjian, H; Plunkett, W; Tarassoff, P	1
Matsuda, A; Sasaki, T; Takenuki, K; Ueda, T	1
Bhalla, K; Grant, S; McCrady, C	1
Abbruzzese, J; Grunewald, R; Kantarjian, H; Keating, MJ; Plunkett, W; Tarassoff, P	1
Gandhi, V; Plunkett, W	1
Arlin, Z; Baker, M; Bhalla, K; Cole, J; Graham, G; Grant, S; MacLaughlin, W	2
Akiyama, Y; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A	1
Botti, RE; Imperia, PS; Lass, JH; Lazarus, HM; Mack, RJ	1
Hiramoto-Yoshioka, A; Hirota, Y; Matsuda, A; Minowada, J; Otani, T; Tanaka, S; Ueda, T; Wataya, Y	1
Akiyama, Y; Kiriyama, Y; Kitoh, T; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A	1
Shirai, T; Umeda, M	1
Fondu, P; Lebacq, AM; Mandelbaum, IM; Vertongen, F	1
Bergstrom, D; Kahilainen, L; Kangas, L; Vilpo, JA	1
Kinkade, JM	1
Tarakanova, MP	1

Reviews

2 review(s) available for deoxycytidine and Leucocythaemia

Article	Year
Role of differentiation induction in action of purine antimetabolites. Pharmacy world & science : PWS, 1994, Apr-15, Volume: 16, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Cell Differentiation; Deoxycytidine; Gemcitabine; Humans; Leukemia; Oncogenes; Ribavirin	1994
Gemcitabine in hematologic malignancies. Current opinion in oncology, 2001, Volume: 13, Issue:6 Topics: Antimetabolites, Antineoplastic; Clinical Trials as Topic; Deoxycytidine; DNA; Gemcitabine; Hodgkin Disease; Humans; Leukemia; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Tumor Cells, Cultured	2001

Trials

8 trial(s) available for deoxycytidine and Leucocythaemia

Article	Year
Phase I study of gemcitabine (difluorodeoxycytidine) in children with relapsed or refractory leukemia (CCG-0955): a report from the Children's Cancer Group. Leukemia & lymphoma, 2002, Volume: 43, Issue:10 Topics: Adolescent; Biotransformation; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Chromatography, High Pressure Liquid; Deoxycytidine; Female; Gemcitabine; Half-Life; Humans; Infant; Leukemia; Male; Maximum Tolerated Dose; Metabolic Clearance Rate; Salvage Therapy	2002
A new multidrug reinduction protocol with topotecan, vinorelbine, thiotepa, dexamethasone, and gemcitabine for relapsed or refractory acute leukemia. Leukemia, 2003, Volume: 17, Issue:10 Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Deoxycytidine; Dexamethasone; Drug Administration Schedule; Female; Gemcitabine; Humans; Leukemia; Male; Recurrence; Thiotepa; Topotecan; Treatment Outcome; Vinblastine; Vinorelbine	2003
Immunochemical detection of urinary 5-methyl-2'-deoxycytidine as a potential biologic marker for leukemia. Clinica chimica acta; international journal of clinical chemistry, 1995, Jan-31, Volume: 234, Issue:1-2 Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Biomarkers, Tumor; Chromatography, Affinity; Chromatography, High Pressure Liquid; Cross Reactions; Deoxycytidine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hybridomas; Immunochemistry; Leukemia; Mice; Mice, Inbred BALB C	1995
Phase I study of a continuous infusion of high-dose ara-C in conjunction with a fixed dose of 2'-deoxycytidine (IND 28108) in patients with refractory leukemia: an interim report. Leukemia, 1993, Volume: 7, Issue:12 Topics: Adult; Aged; Blast Crisis; Cytarabine; Deoxycytidine; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Remission Induction; Thrombocytopenia	1993
Phase I evaluation of prolonged-infusion gemcitabine with mitoxantrone for relapsed or refractory acute leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Feb-01, Volume: 20, Issue:3 Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Gemcitabine; Humans; Infusions, Intravenous; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Middle Aged; Mitoxantrone; Neural Tube Defects	2002
Phase I evaluation of prolonged-infusion gemcitabine with irinotecan for relapsed or refractory leukemia or lymphoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Jul-01, Volume: 20, Issue:13 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Camptothecin; Deoxycytidine; Drug Administration Schedule; Esophagitis; Evaluation Studies as Topic; Female; Gemcitabine; Humans; Infusions, Intravenous; Irinotecan; Leukemia; Lymphoma; Male; Middle Aged; Nausea; Neutropenia; Recurrence; Stomatitis; Treatment Outcome; Vomiting	2002
Gemcitabine in leukemia: a phase I clinical, plasma, and cellular pharmacology study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:3 Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Deoxycytidine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Evaluation; Gemcitabine; Humans; Leukemia; Middle Aged	1992
An in vitro method which assesses corneal epithelial toxicity due to antineoplastic, preservative and antimicrobial agents. Lens and eye toxicity research, 1989, Volume: 6, Issue:1-2 Topics: Adult; Aged; Aminoglycosides; Animals; Antineoplastic Agents; Antiviral Agents; Cells, Cultured; Cornea; Cytarabine; Deoxycytidine; Double-Blind Method; Epithelium; Female; Hodgkin Disease; Humans; Keratitis; Leukemia; Male; Middle Aged; Preservatives, Pharmaceutical; Rabbits; Thymidine; Toxicology	1989

Other Studies

58 other study(ies) available for deoxycytidine and Leucocythaemia

Article	Year
Molecular Imaging of Deoxycytidine Kinase Activity Using Deoxycytidine-Enhanced CEST MRI. Cancer research, 2019, 05-15, Volume: 79, Issue:10 Topics: Animals; Cell Line, Tumor; Deoxycytidine; Deoxycytidine Kinase; Female; Heterografts; Leukemia; Magnetic Resonance Imaging; Mice; Mice, Inbred NOD; Mice, SCID; Substrate Specificity	2019
Noninvasive prediction of tumor responses to gemcitabine using positron emission tomography. Proceedings of the National Academy of Sciences of the United States of America, 2009, Feb-24, Volume: 106, Issue:8 Topics: Animals; Antineoplastic Agents; Cytosine; Deoxycytidine; Gemcitabine; Humans; Leukemia; Mice; Positron-Emission Tomography	2009
Induction of resistance to the lipophilic cytarabine prodrug elacytarabine (CP-4055) in CEM leukemic cells. Nucleosides, nucleotides & nucleic acids, 2010, Volume: 29, Issue:4-6 Topics: Antineoplastic Agents; Cell Line, Tumor; Cytarabine; Cytidine Deaminase; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Humans; Leukemia; Nucleoside Deaminases; Polymerase Chain Reaction	2010
Liposomal squalenoyl-gemcitabine: formulation, characterization and anticancer activity evaluation. Nanoscale, 2010, Volume: 2, Issue:8 Topics: Animals; Antimetabolites, Antineoplastic; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Deoxycytidine; Gemcitabine; Leukemia; Liposomes; Mice; Particle Size; Polyethylene Glycols; Prodrugs; Scattering, Small Angle; Squalene; X-Ray Diffraction	2010
Interaction of fused-pyrimidine nucleoside analogs with human concentrative nucleoside transporters: High-affinity inhibitors of human concentrative nucleoside transporter 1. Biochemical pharmacology, 2011, Jan-01, Volume: 81, Issue:1 Topics: Animals; Antineoplastic Agents; Biological Transport; Cell Line, Tumor; Cell Proliferation; Cytoprotection; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Humans; Leukemia; Membrane Transport Proteins; Molecular Structure; Oocytes; Pyrimidine Nucleosides; Saccharomyces cerevisiae; Xenopus laevis	2011
Metabolism and accumulation of the lipophilic deoxynucleoside analogs elacytarabine and CP-4126. Investigational new drugs, 2012, Volume: 30, Issue:5 Topics: Antineoplastic Agents; Cell Line; Cytarabine; Deoxycytidine; Deoxycytidine Kinase; Dipyridamole; Drug Resistance, Neoplasm; Gemcitabine; Humans; Leukemia; Nucleoside Transport Proteins; Nucleotidases	2012
Combination effects of digalloylresveratrol with arabinofuranosylcytosine and difluorodeoxycytidine in human leukemia and pancreatic cancer cells. Nucleosides, nucleotides & nucleic acids, 2011, Volume: 30, Issue:12 Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Cytarabine; Deoxycytidine; Gallic Acid; Gemcitabine; HL-60 Cells; Humans; Leukemia; Pancreatic Neoplasms; Stilbenes; Tumor Stem Cell Assay	2011
Delayed addition of deoxycytidine protects normal CD34+ cells against cytotoxicity of gemcitabine without compromising its activity against human leukemic cells. Stem cells (Dayton, Ohio), 2003, Volume: 21, Issue:3 Topics: Antigens, CD34; Antineoplastic Agents; Bone Marrow Cells; Cell Division; Coculture Techniques; Cytotoxins; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Resistance, Neoplasm; Drug Therapy, Combination; Gemcitabine; Hematopoietic Stem Cells; HL-60 Cells; Humans; Immunosuppressive Agents; Leukemia; T-Lymphocytes	2003
In vitro cytotoxicity of aplidin and crossresistance with other cytotoxic drugs in childhood leukemic and normal bone marrow and blood samples: a rational basis for clinical development. Leukemia, 2003, Volume: 17, Issue:7 Topics: Antineoplastic Agents; Blood Cells; Bone Marrow; Carnitine; Case-Control Studies; Cell Survival; Child; Deoxycytidine; Depsipeptides; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Drug Resistance, Neoplasm; Gemcitabine; Humans; Leukemia; Peptides, Cyclic; Podophyllotoxin	2003
The effects of 5-fluorodeoxycytidine, 5-fluorodeoxyuridine, and related compounds on transplanted mouse leukemias. Cancer research, 1959, Volume: 19, Issue:5 Topics: Animals; Antineoplastic Agents; Deoxycytidine; Floxuridine; Leukemia; Leukemia, Experimental; Mice; Nucleosides; Nucleotides	1959
Clinical and pharmacological studies with 5-iodo-2'-deoxycytidine. Cancer research, 1963, Volume: 23 Topics: Adenocarcinoma; Bromodeoxycytidine; Carcinoma; Carcinoma, Squamous Cell; Deoxycytidine; Hodgkin Disease; Humans; Idoxuridine; Leukemia; Nucleosides	1963
EFFECT OF DEOXYCYTIDINE ON THE RATE OF BIOSYNTHESIS OF PHOSPHORYLATED DERIVATIVES OF THYMIDINE. Biochimica et biophysica acta, 1964, Feb-17, Volume: 80 Topics: Carbon Isotopes; Chromatography; Deoxycytidine; Formates; Idoxuridine; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Nucleosides; Nucleotides; Pharmacology; Phosphorylation; Research; Thymidine	1964
THE REVERSAL OF CYTOSINE ARABINOSIDE ACTIVITY IN VIVO BY DEOXYCYTIDINE. Biochemical pharmacology, 1964, Volume: 13 Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cytarabine; Cytosine; Deoxycytidine; Leukemia; Leukemia, Experimental; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Research; Sarcoma 180	1964
Antiproliferative activity and mechanism of action of fatty acid derivatives of gemcitabine in leukemia and solid tumor cell lines and in human xenografts. Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9 Topics: Animals; Antimetabolites, Antineoplastic; Carbon; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cytidine Deaminase; Deoxycytidine; DNA; DNA Damage; Fatty Acids; Gemcitabine; Humans; Inhibitory Concentration 50; Leukemia; Melanoma; Mice; Mice, Nude; Models, Chemical; Neoplasm Transplantation; Nucleoside Deaminases; Phosphorylation; Rats; Time Factors	2004
Antiproliferative activity and mechanism of action of fatty acid derivatives of arabinosylcytosine (ara-C) in leukemia and solid tumor cell lines. Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9 Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Proliferation; Cytarabine; Deoxycytidine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fatty Acids; Gemcitabine; Humans; Inhibitory Concentration 50; Leukemia; Mice; Neoplasms; Rats; Time Factors	2004
Determination of the importance of the stereochemistry of psorospermin in topoisomerase II-induced alkylation of DNA and in vitro and in vivo biological activity. Molecular cancer therapeutics, 2005, Volume: 4, Issue:11 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cell Line; Cell Line, Tumor; Deoxycytidine; DNA; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Epoxy Compounds; Gemcitabine; In Vitro Techniques; Inhibitory Concentration 50; Leukemia; Lymphoma; Mice; Mice, Nude; Models, Chemical; Models, Molecular; Pancreatic Neoplasms; Stereoisomerism; Time Factors; Xanthones	2005
Diverse resveratrol sensitization to apoptosis induced by anticancer drugs in sensitive and resistant leukemia cells. Neoplasma, 2006, Volume: 53, Issue:5 Topics: Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Busulfan; Cell Cycle; Cell Line, Tumor; Cycloheximide; Deoxycytidine; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Gemcitabine; Humans; Leukemia; Paclitaxel; Resveratrol; Stilbenes	2006
Preclinical toxicology (subacute and acute) and efficacy of a new squalenoyl gemcitabine anticancer nanomedicine. The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:2 Topics: Animals; Antineoplastic Agents; Cytarabine; Deoxycytidine; Drug Evaluation, Preclinical; Gemcitabine; Leukemia; Mice; Mice, Inbred DBA; Nanomedicine; Nanostructures; Squalene; Treatment Outcome	2008
Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells. Leukemia & lymphoma, 2008, Volume: 49, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Cytarabine; Deoxycytidine; Drug Interactions; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Hydrazines; Idarubicin; Irinotecan; Leukemia; Lymphoma; Sulfonamides; Topotecan	2008
5-Methyl-2'-deoxycytidine. Metabolism and effects on cell lethality studied with human leukemic cells in vitro. Molecular pharmacology, 1984, Volume: 25, Issue:3 Topics: Cell Division; Cell Line; Cell Survival; Deoxycytidine; Deoxyribonucleosides; Humans; Leukemia; Leukemia, Lymphoid	1984
Cytosine arabinoside transport by human leukaemic cells. European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:8 Topics: Acute Disease; Adolescent; Adult; Aged; Biological Transport; Cell Membrane; Child; Child, Preschool; Cytarabine; Deoxycytidine; Humans; Infant; Kinetics; Leukemia; Leukocytes; Middle Aged; Phloretin; Thioinosine	1983
Thymidine as a kinetic and biochemical modulator of 1-beta-D-arabinofuranosylcytosine in human acute nonlymphocytic leukemia. Cancer research, 1984, Volume: 44, Issue:2 Topics: Acute Disease; Adult; Cytarabine; Deoxycytidine; Female; Humans; Interphase; Kinetics; Leukemia; Male; Middle Aged; Phosphorylation; Thymidine	1984
Effects of deoxynucleosides on cultured human leukemia cell growth and deoxynucleotide pools. Cancer research, 1981, Volume: 41, Issue:11 Pt 1 Topics: Adenosine Deaminase; Cell Cycle; Cell Line; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; Deoxyribonucleotides; DNA; Humans; Leukemia	1981
Mechanism of deoxycytidine rescue of thymidine toxicity in human T-leukemic lymphocytes. Cancer research, 1980, Volume: 40, Issue:5 Topics: Cell Division; Cell Line; Deoxycytidine; Deoxyribonucleotides; DNA Replication; Humans; Leukemia; Lymphocytes; Ribonucleotide Reductases; Thymidine	1980
Deoxycytidine and deoxythymidine kinase activities in plasma of mice and patients with neoplastic disease. Cancer research, 1982, Volume: 42, Issue:6 Topics: Adolescent; Adult; Aged; Animals; Deoxycytidine; Female; Humans; Leukemia; Leukemia, Experimental; Male; Mice; Mice, Inbred AKR; Mice, Inbred Strains; Middle Aged; Neoplasms; Thymidine Kinase	1982
Difluorodeoxyguanosine: cytotoxicity, metabolism, and actions on DNA synthesis in human leukemia cells. Seminars in oncology, 1995, Volume: 22, Issue:4 Suppl 11 Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Arabinonucleosides; Base Sequence; Cricetinae; Deoxycytidine; Deoxyguanosine; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Gemcitabine; Humans; Leukemia; Molecular Sequence Data; Nucleotides; Peptide Chain Elongation, Translational; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); RNA, Neoplasm; Structure-Activity Relationship; Tumor Cells, Cultured	1995
Evaluation of the cytotoxic activity of gemcitabine in primary cultures of tumor cells from patients with hematologic or solid tumors. Seminars in oncology, 1995, Volume: 22, Issue:4 Suppl 11 Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Cisplatin; Cladribine; Colorectal Neoplasms; Cytarabine; Deoxycytidine; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Gemcitabine; Humans; In Vitro Techniques; Leukemia; Lung Neoplasms; Lymphoma; Ribonucleotide Reductases; Tumor Cells, Cultured; Urogenital Neoplasms	1995
Nucleoside triphosphate donors for nucleoside kinases: donor properties of UTP with human deoxycytidine kinase. Biochemical and biophysical research communications, 1995, Nov-02, Volume: 216, Issue:1 Topics: Adenosine Triphosphate; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Humans; Kinetics; Leukemia; Phosphorus Radioisotopes; Radioisotope Dilution Technique; Spleen; Substrate Specificity; Tritium; Uridine Triphosphate	1995
Seeking the nucleoside transporter. Nature medicine, 1997, Volume: 3, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Carrier Proteins; Cell Membrane; Cladribine; Cloning, Molecular; Cytarabine; Deoxycytidine; Erythrocytes; Gemcitabine; Glucose Transporter Type 1; Humans; Leukemia; Lymphoma; Membrane Proteins; Monosaccharide Transport Proteins; Nucleosides; Oocytes; Recombinant Proteins; Uridine; Vidarabine; Xenopus	1997
Differential incorporation of ara-C, gemcitabine, and fludarabine into replicating and repairing DNA in proliferating human leukemia cells. Blood, 1997, Jul-01, Volume: 90, Issue:1 Topics: Antineoplastic Agents; Binding Sites; Cytarabine; Deoxycytidine; DNA Repair; DNA Replication; DNA, Neoplasm; Gemcitabine; Humans; Leukemia; Tumor Cells, Cultured; Vidarabine	1997
Regulation of deoxycytidine kinase by deoxycytidine and deoxycytidine 5' triphosphate in whole leukemia and tumor cells. Advances in experimental medicine and biology, 1998, Volume: 431 Topics: Animals; Arabinofuranosylcytosine Triphosphate; CHO Cells; Cricetinae; Cytarabine; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; HL-60 Cells; Homeostasis; Humans; Leukemia; Ribonucleotide Reductases; Tumor Cells, Cultured	1998
Inhibition of protein kinase C activator-mediated induction of p21CIP1 and p27KIP1 by deoxycytidine analogs in human leukemia cells: relationship to apoptosis and differentiation. Biochemical pharmacology, 1999, Jul-01, Volume: 58, Issue:1 Topics: Antimetabolites, Antineoplastic; Apoptosis; Bryostatins; Cell Cycle Proteins; Cell Differentiation; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cytarabine; Deoxycytidine; Drug Interactions; Enzyme Activation; Gemcitabine; Humans; Lactones; Leukemia; Macrolides; Microtubule-Associated Proteins; Mitogens; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins; U937 Cells	1999
Supraadditive effect of 2',2'-difluorodeoxycytidine (gemcitabine) in combination with oxaliplatin in human cancer cell lines. Cancer chemotherapy and pharmacology, 1999, Volume: 44, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Deoxycytidine; DNA; Gemcitabine; Humans; Leukemia; Organoplatinum Compounds; Oxaliplatin; Tumor Cells, Cultured	1999
2-Chloro-2'-deoxyadenosine induces apoptosis through the Fas/Fas ligand pathway in human leukemia cell line MOLT-4. Leukemia, 2000, Volume: 14, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cladribine; Cycloheximide; Cysteine Proteinase Inhibitors; Deoxycytidine; DNA Fragmentation; DNA, Neoplasm; Enzyme Activation; fas Receptor; Flow Cytometry; Fluorometry; Humans; In Situ Nick-End Labeling; Leukemia; Oligopeptides; Phosphorylation; Tumor Cells, Cultured	2000
Differential effects of gemcitabine on ribonucleotide pools of twenty-one solid tumour and leukaemia cell lines. Biochimica et biophysica acta, 2000, Mar-06, Volume: 1474, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Deoxycytidine; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Leukemia; Lung Neoplasms; Mice; Ovarian Neoplasms; Rats; Ribonucleotide Reductases; Ribonucleotides; Tumor Cells, Cultured	2000
Liquid chromatographic determination of urinary 5-methyl-2'-deoxycytidine and pseudouridine as potential biological markers for leukaemia. Journal of pharmaceutical and biomedical analysis, 1999, Volume: 21, Issue:5 Topics: Acute Disease; Biomarkers, Tumor; Chromatography, High Pressure Liquid; Deoxycytidine; Female; Humans; Leukemia; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pseudouridine; Sensitivity and Specificity	1999
Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines. Cancer research, 2001, Oct-01, Volume: 61, Issue:19 Topics: Amino Acid Sequence; Antineoplastic Agents; Biological Transport; Carrier Proteins; Cytarabine; Cytidine Deaminase; Cytosine; Deoxycytidine; Deoxycytidine Kinase; Dioxolanes; Drug Resistance, Neoplasm; Gemcitabine; Humans; Leukemia; Male; Membrane Proteins; Molecular Sequence Data; Nucleoside Transport Proteins; Phosphorylation; Prostatic Neoplasms; Sequence Homology, Amino Acid; Sodium; Stereoisomerism; Tritium; Tumor Cells, Cultured; Uridine	2001
Selection of drug-resistant transduced cells with cytosine nucleoside analogs using the human cytidine deaminase gene. Cancer gene therapy, 2001, Volume: 8, Issue:9 Topics: Antimetabolites, Antineoplastic; Azacitidine; Bone Marrow Cells; Colony-Forming Units Assay; Cytarabine; Cytidine Deaminase; Decitabine; Deoxycytidine; DNA Modification Methylases; Drug Evaluation; Drug Resistance; Enzyme Inhibitors; Flow Cytometry; Gene Transfer Techniques; Genetic Vectors; Green Fluorescent Proteins; Humans; Leukemia; Luminescent Proteins; Retroviridae; Transgenes	2001
Deoxycytidine kinase: properties of the enzyme from human leukemic granulocytes. Blood, 1975, Volume: 46, Issue:5 Topics: Azacitidine; Blood Proteins; Cell Separation; Cell-Free System; Cytarabine; Cytidine Deaminase; Deoxycytidine; Granulocytes; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Molecular Weight; Phosphates; Phosphotransferases; Tissue Extracts; Uridine Kinase	1975
Effects of 5-fluorodeoxyuridine on cell viability and uptake of deoxycytidine and (3H)cytosine arabinoside in L5178Y cells. Biochemical pharmacology, 1976, Feb-01, Volume: 25, Issue:3 Topics: Animals; Cells, Cultured; Cytarabine; Deoxycytidine; DNA; Floxuridine; Kinetics; Leukemia; Mice; RNA	1976
Metabolism and toxicity of 9-beta-D-arabinofuranosyladenine in human malignant T cells and B cells in tissue culture. Advances in experimental medicine and biology, 1979, Volume: 122B Topics: Adenosine Kinase; B-Lymphocytes; Cell Division; Cell Line; Deoxycytidine; Humans; Kinetics; Leukemia; T-Lymphocytes; Vidarabine	1979
Nuclear incorporation of radioactive DNA precursors and progression of cells through S. Combined radioautographic and cytophotometric studies on normal and leukaemic bone marrow and thoracic duct lymph cells of man. Cell and tissue kinetics, 1975, Volume: 8, Issue:5 Topics: Aged; Bone Marrow; Bone Marrow Cells; Cell Nucleus; Child; Child, Preschool; Deoxycytidine; DNA; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Lymphocytes; Male; Mitosis; Scleroderma, Systemic; Thymidine; Tritium	1975
Selective assays for thymidine kinase 1 and 2 and deoxycytidine kinase and their activities in extracts from human cells and tissues. Biochemical and biophysical research communications, 1992, Oct-30, Volume: 188, Issue:2 Topics: Arabinonucleosides; Cladribine; Deoxycytidine; Deoxycytidine Kinase; Humans; Isoenzymes; Kinetics; Leukemia; Leukocytes; Mitochondria; Organ Specificity; Phosphorylation; Radioisotope Dilution Technique; Reference Values; Substrate Specificity; Thymidine; Thymidine Kinase; Tritium; Tumor Cells, Cultured; Zidovudine	1992
[Clinical application of enzyme inhibitors--hematologic malignancies]. Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:9 Topics: Cytarabine; Deoxycytidine; DNA Topoisomerases, Type I; Etoposide; Gemcitabine; Humans; Leukemia; Mercaptopurine; Methotrexate; Purines; Pyrimidines; Thioguanine; Topoisomerase I Inhibitors	1991
Nucleosides and nucleotides. 94. Radical deoxygenation of tert-alcohols in 1-(2-C-alkylpentofuranosyl) pyrimidines: synthesis of (2'S)-2'-deoxy-2'-C-methylcytidine, an antileukemic nucleoside. Journal of medicinal chemistry, 1991, Volume: 34, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Deoxycytidine; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Leukemia; Leukemia L1210; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Molecular Structure; Neoplasms; Structure-Activity Relationship	1991
Effect of tetrahydrouridine and deoxytetrahydrouridine on the interaction between 2'-deoxycytidine and 1-beta-D-arabinofuranosylcytosine in human leukemia cells. Leukemia research, 1991, Volume: 15, Issue:4 Topics: Arabinofuranosylcytosine Triphosphate; Cell Division; Cytarabine; Cytidine Deaminase; DCMP Deaminase; Deamination; Deoxycytidine; Deoxycytosine Nucleotides; DNA, Neoplasm; Humans; Leukemia; Tetrahydrouridine; Tumor Cells, Cultured	1991
Pharmacologically directed design of the dose rate and schedule of 2',2'-difluorodeoxycytidine (Gemcitabine) administration in leukemia. Cancer research, 1990, Nov-01, Volume: 50, Issue:21 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Cytidine Triphosphate; Deoxycytidine; Drug Administration Schedule; Female; Gemcitabine; Humans; Infusions, Intravenous; Leukemia; Male; Middle Aged; Neoplastic Cells, Circulating	1990
Modulatory activity of 2',2'-difluorodeoxycytidine on the phosphorylation and cytotoxicity of arabinosyl nucleosides. Cancer research, 1990, Jun-15, Volume: 50, Issue:12 Topics: Arabinonucleosides; Arabinonucleotides; Cytarabine; Deoxycytidine; Gemcitabine; Humans; Leukemia; Phosphorylation; Tumor Cells, Cultured; Vidarabine	1990
Effect of deoxycytidine on the metabolism and cytotoxicity of 5-aza-2'-deoxycytidine and arabinosyl 5-azacytosine in normal and leukemic human myeloid progenitor cells. Leukemia, 1987, Volume: 1, Issue:12 Topics: Acute Disease; Azacitidine; Bone Marrow; Decitabine; Deoxycytidine; Deoxycytosine Nucleotides; DNA, Neoplasm; Hematopoietic Stem Cells; Humans; Leukemia; Neoplastic Stem Cells	1987
Differential modulation of 1-beta-D-arabinofuranosylcytosine metabolism by hydroxyurea in human leukemic cell lines. Biochemical pharmacology, 1988, May-01, Volume: 37, Issue:9 Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; B-Lymphocytes; Cell Line; Cytarabine; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxycytidine; Deoxycytosine Nucleotides; Humans; Hydroxyurea; Leukemia; T-Lymphocytes; Thymine Nucleotides; Vidarabine Phosphate	1988
The mechanism of 2-chlorodeoxyadenosine-induced cell death. Advances in experimental medicine and biology, 1989, Volume: 253B Topics: 2-Chloroadenosine; Cell Survival; Cladribine; Cycloheximide; Deoxyadenosines; Deoxycytidine; DNA Damage; Humans; Leukemia; Lymphoma; Tumor Cells, Cultured	1989
Ara-CTP metabolism following hydroxyurea or methotrexate treatment in human leukemia cell lines. Advances in experimental medicine and biology, 1989, Volume: 253B Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; Drug Synergism; Humans; Hydroxyurea; Leukemia; Leukemia, Promyelocytic, Acute; Methotrexate; Thymine Nucleotides; Tumor Cells, Cultured	1989
[Relationship between Ara-C sensitivity of leukemic-colony forming units (L-CFU) and [3H] deoxycytidine suicide test of L-CFU]. Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1989, Volume: 52, Issue:3 Topics: Adult; Aged; Cell Survival; Cytarabine; Deoxycytidine; Female; Humans; Leukemia; Male; Middle Aged; Neoplastic Stem Cells; Thymidine; Tritium; Tumor Stem Cell Assay	1989
Deoxythymidine and deoxycytidine incorporation into DNA in B leukemic cells. American journal of hematology, 1986, Volume: 21, Issue:3 Topics: B-Lymphocytes; Deoxycytidine; Deoxycytidine Kinase; DNA; Humans; Leukemia; Phenotype; Thymidine	1986
Deoxycytidine preferentially protects normal versus leukemic myeloid progenitor cells from cytosine arabinoside-mediated cytotoxicity. Blood, 1987, Volume: 70, Issue:2 Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cytarabine; Deoxycytidine; DNA; Humans; Leukemia; Neoplastic Stem Cells; Phosphates; Stem Cells	1987
In vitro and in vivo studies of a promising antileukemic thymidine analogue, 5-hydroxymethyl-2' deoxyuridine. Biochemical pharmacology, 1986, Dec-01, Volume: 35, Issue:23 Topics: Animals; Antineoplastic Agents; Blood Platelets; Cell Line; Deoxycytidine; Humans; Leukemia; Leukemia L1210; Thymidine	1986
Effects of 5-bromo-2'-deoxyuridine (BUdR) on in vitro colony formation in cultures of mouse bone marrow cells. FEBS letters, 1974, Jan-15, Volume: 38, Issue:3 Topics: Animals; Bone Marrow; Bone Marrow Cells; Bromodeoxyuridine; Cell Aggregation; Cells, Cultured; Centrifugation, Density Gradient; Chromatography, Gel; Chromatography, Ion Exchange; Culture Media; Deoxycytidine; DNA; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Male; Mice; Mice, Inbred C57BL; Proteinuria; Thymidine; Time Factors; Tritium	1974
[Excretion of desoxycytidine in patients with leukemia following general gamma-irradiation]. Meditsinskaia radiologiia, 1971, Volume: 16, Issue:2 Topics: Acute Disease; Deoxycytidine; Gamma Rays; Humans; Leukemia; Radiation Effects; Radiotherapy Dosage; Time Factors	1971