deoxycytidine and Granulocytic Leukemia

deoxycytidine has been researched along with Granulocytic Leukemia in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19907 (33.33)18.7374
1990's6 (28.57)18.2507
2000's7 (33.33)29.6817
2010's1 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ewald, B; Plunkett, W; Sampath, D1
Advani, AS; Ali-Osman, F; Barker, A; Beaven, A; Copelan, E; de Castro, CM; Diehl, LF; Kalaycio, M; Moore, JO; Rizzieri, DA; Rybicki, L; Sekeres, MA; Shadman, M; Sobecks, R; Talea, P1
Adams, DJ; Colvin, OM; Flowers, JL; Rizzieri, DA; Shanks, RH1
Blum, W; Byrd, J; Chan, KK; Klisovic, R; Liu, S; Liu, Z; Marcucci, G; Paschka, P; Perrotti, D; Xie, Z1
Ahmad, R; Al-Obaidi, MJ; Dawson, C; Hughes, G; O'Reilly, E; Ramesh, S; Riddle, P; Sekhar, M; Shapiro, S; Smith, J1
Carlson, J; Keoffler, HP; Yen, J1
Akman, SA; Andrews, PA; Bachur, NR; Chou, FE; Rosen, H; Ross, DD; Salinger, C1
Mejer, J1
Honders, MW; Kester, MG; Landegent, JE; Stegmann, AP; Willemze, R1
Aresta, A; Liso, V; Palmisano, F; Specchia, G; Zambonin, CG1
Braess, J; Hiddemann, W; Jahns-Streubel, G; Kern, W; Keye, S; Schleyer, E; Unterhalt, M; Wegendt, C1
Dumontet, C; Galmarini, CM; Mackey, JR1
Achanta, G; Feng, L; Huang, P; Pelicano, H; Plunkett, W1
Chabner, BA; Coleman, CN; Drake, JC; Stoller, RG1
Chabner, BA; Coleman, CN; Johns, DG1
Baguley, BC; Falkenhaug, EM1
Plunkett, W; Xu, YZ1
Chou, TC; Kong, XB; Tong, WP1
Bouffard, DY; Momparler, LF; Momparler, RL1
Arlin, Z; Bhalla, K; Grant, S; Howe, CW1
Ho, DH1

Reviews

1 review(s) available for deoxycytidine and Granulocytic Leukemia

ArticleYear
Nucleoside analogues: mechanisms of drug resistance and reversal strategies.
    Leukemia, 2001, Volume: 15, Issue:6

    Topics: 2-Chloroadenosine; 5'-Nucleotidase; Acute Disease; Animals; Antimetabolites, Antineoplastic; Arabinonucleosides; Biological Transport; Carrier Proteins; Cytarabine; Cytidine Deaminase; Cytosine; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Dioxolanes; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Drug Resistance, Neoplasm; Gemcitabine; Hematopoietic Cell Growth Factors; Humans; Leukemia, Myeloid; Lymphoproliferative Disorders; Neoplastic Stem Cells; Nucleosides; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Remission Induction; Ribonucleotide Reductases; Vidarabine

2001

Trials

1 trial(s) available for deoxycytidine and Granulocytic Leukemia

ArticleYear
A Phase II trial of gemcitabine and mitoxantrone for patients with acute myeloid leukemia in first relapse.
    Clinical lymphoma, myeloma & leukemia, 2010, Volume: 10, Issue:6

    Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Deoxycytidine; Drug Resistance, Multiple; Equilibrative-Nucleoside Transporter 2; Female; Fever; Gemcitabine; Gene Expression Regulation, Leukemic; Glutathione S-Transferase pi; Humans; Immunohistochemistry; Infusions, Intravenous; K562 Cells; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Multidrug Resistance-Associated Proteins; Recurrence; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; U937 Cells

2010

Other Studies

19 other study(ies) available for deoxycytidine and Granulocytic Leukemia

ArticleYear
ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance.
    Cancer research, 2008, Oct-01, Volume: 68, Issue:19

    Topics: Acid Anhydride Hydrolases; Animals; Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Survival; Cells, Cultured; Deoxycytidine; DNA Repair Enzymes; DNA Replication; DNA-Binding Proteins; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid; Mice; Models, Biological; MRE11 Homologue Protein; Multiprotein Complexes; Nuclear Proteins; Nucleosides; Protein Serine-Threonine Kinases; Tumor Stem Cell Assay; Tumor Suppressor Proteins

2008
Preclinical evaluation of gemcitabine combination regimens for application in acute myeloid leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Jun-01, Volume: 11, Issue:11

    Topics: Acute Disease; Antineoplastic Agents; Apoptosis; Camptothecin; Caspase 3; Caspase 7; Caspases; Cell Cycle; Chlorambucil; Deoxycytidine; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation, Preclinical; Drug Interactions; Enzyme Activation; Flow Cytometry; Gemcitabine; Humans; Irinotecan; Leukemia, Myeloid; Mitoxantrone; Paclitaxel; U937 Cells; Vidarabine

2005
Characterization of in vitro and in vivo hypomethylating effects of decitabine in acute myeloid leukemia by a rapid, specific and sensitive LC-MS/MS method.
    Nucleic acids research, 2007, Volume: 35, Issue:5

    Topics: Acute Disease; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Chromatography, Liquid; Clinical Trials, Phase I as Topic; Decitabine; Deoxycytidine; Deoxyguanosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Humans; Leukemia, Myeloid; Tandem Mass Spectrometry

2007
Acute myeloid leukaemia secondary to treatment with capecitabine for metastatic colorectal cancer.
    European journal of haematology, 2007, Volume: 78, Issue:6

    Topics: Acute Disease; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Humans; Leukemia, Myeloid

2007
The study of human myeloid differentiation using bromodeoxyuridine (BrdU).
    Journal of cellular physiology, 1983, Volume: 116, Issue:1

    Topics: Bromodeoxyuridine; Cell Differentiation; Cell Line; Deoxycytidine; DNA; Granulocytes; Humans; Idoxuridine; Kinetics; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Thymidine; Thymidine Kinase

1983
Growth inhibition by thymidine of leukemic HL-60 and normal human myeloid progenitor cells.
    Cancer research, 1981, Volume: 41, Issue:6

    Topics: Cell Differentiation; Cell Line; Clone Cells; Colony-Forming Units Assay; Deoxycytidine; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Thymidine; Time Factors

1981
Enzymatic studies on possible improvement of cytosine arabinoside treatment.
    Scandinavian journal of clinical and laboratory investigation, 1981, Volume: 41, Issue:1

    Topics: Adult; Cell Extracts; Cytarabine; Cytidine Deaminase; Deamination; Deoxycytidine; Deoxycytidine Kinase; Female; Humans; Leukemia, Myeloid; Leukocytes; Male; Middle Aged; Phosphorylation

1981
Role of deoxycytidine kinase in an in vitro model for AraC- and DAC-resistance: substrate-enzyme interactions with deoxycytidine, 1-beta-D-arabinofuranosylcytosine and 5-aza-2'-deoxycytidine.
    Leukemia, 1993, Volume: 7, Issue:7

    Topics: Acute Disease; Animals; Antineoplastic Agents; Azacitidine; Binding, Competitive; Cytarabine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; Drug Resistance; In Vitro Techniques; Kinetics; Leukemia, Myeloid; Rats; Rats, Inbred BN; Tumor Cells, Cultured

1993
Liquid chromatographic determination of urinary 5-methyl-2'-deoxycytidine and pseudouridine as potential biological markers for leukaemia.
    Journal of pharmaceutical and biomedical analysis, 1999, Volume: 21, Issue:5

    Topics: Acute Disease; Biomarkers, Tumor; Chromatography, High Pressure Liquid; Deoxycytidine; Female; Humans; Leukemia; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pseudouridine; Sensitivity and Specificity

1999
Successful modulation of high-dose cytosine arabinoside metabolism in acute myeloid leukaemia by haematopoietic growth factors: no effect of ribonucleotide reductase inhibitors fludarabine and gemcitabine.
    British journal of haematology, 2000, Volume: 109, Issue:2

    Topics: Arabinofuranosylcytosine Triphosphate; Cytarabine; Deoxycytidine; Deoxycytidine Kinase; Drug Administration Schedule; Enzyme Inhibitors; Gemcitabine; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Humans; Immunosuppressive Agents; Leukemia, Myeloid; Ribonucleotide Reductases; Vidarabine

2000
Interaction of p53 and DNA-PK in response to nucleoside analogues: potential role as a sensor complex for DNA damage.
    Cancer research, 2001, Dec-15, Volume: 61, Issue:24

    Topics: Antigens, Nuclear; Antimetabolites, Antineoplastic; Apoptosis; Binding, Competitive; Deoxycytidine; DNA Damage; DNA Helicases; DNA Repair; DNA Replication; DNA-Activated Protein Kinase; DNA-Binding Proteins; DNA, Neoplasm; Gemcitabine; Humans; Ku Autoantigen; Leukemia, Myeloid; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2001
Deoxycytidine kinase: properties of the enzyme from human leukemic granulocytes.
    Blood, 1975, Volume: 46, Issue:5

    Topics: Azacitidine; Blood Proteins; Cell Separation; Cell-Free System; Cytarabine; Cytidine Deaminase; Deoxycytidine; Granulocytes; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Molecular Weight; Phosphates; Phosphotransferases; Tissue Extracts; Uridine Kinase

1975
Studies on mechanisms of resistance to cytosine arabinoside: problems in the determination of related enzyme activities in leukemic cells.
    Annals of the New York Academy of Sciences, 1975, Aug-08, Volume: 255

    Topics: Bone Marrow; Bone Marrow Cells; Cytarabine; Cytidine Deaminase; Deoxycytidine; Drug Resistance; Erythrocytes; Granulocytes; Humans; Kinetics; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Nucleoside Deaminases; Phosphotransferases; Tetrahydrouridine

1975
Plasma half-life of cytosine arabinoside in patients with leukaemia--the effect of uridine.
    European journal of cancer, 1975, Volume: 11, Issue:1

    Topics: Administration, Oral; Aminohydrolases; Animals; Cell Count; Cytarabine; Deoxycytidine; DNA, Neoplasm; Dose-Response Relationship, Drug; Half-Life; Humans; Leukemia L1210; Leukemia, Myeloid; Leukocytes; Mice; Uridine

1975
Modulation of deoxycytidylate deaminase in intact human leukemia cells. Action of 2',2'-difluorodeoxycytidine.
    Biochemical pharmacology, 1992, Nov-03, Volume: 44, Issue:9

    Topics: Antimetabolites, Antineoplastic; Carbon Radioisotopes; Cell Extracts; Chromatography, High Pressure Liquid; Cytidine Deaminase; DCMP Deaminase; Deoxycytidine; Deoxycytosine Nucleotides; Gemcitabine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Thymine Nucleotides; Tumor Cells, Cultured

1992
Induction of deoxycytidine kinase by 5-azacytidine in an HL-60 cell line resistant to arabinosylcytosine.
    Molecular pharmacology, 1991, Volume: 39, Issue:2

    Topics: Azacitidine; Base Sequence; Cytarabine; Deoxycytidine; Deoxycytidine Kinase; DNA, Neoplasm; Drug Resistance; Enzyme Induction; Humans; Kinetics; Leukemia, Experimental; Leukemia, Myeloid; Methylation; Molecular Sequence Data; Time Factors; Tritium; Tumor Cells, Cultured

1991
Comparison of antineoplastic activity of 2',2'-difluorodeoxycytidine and cytosine arabinoside against human myeloid and lymphoid leukemic cells.
    Anti-cancer drugs, 1991, Volume: 2, Issue:1

    Topics: Antimetabolites, Antineoplastic; Cell Division; Cytarabine; Deoxycytidine; DNA, Neoplasm; Gemcitabine; Humans; Kinetics; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid; Phenotype; Tumor Cells, Cultured

1991
The effect of a prolonged in vitro exposure to 1-beta-D arabinofuranosylcytosine and deoxycytidine on the survival of normal (CFU-GM) and leukemic (L-CFU) human myeloid progenitor cells in suspension culture.
    Experimental hematology, 1990, Volume: 18, Issue:1

    Topics: Cell Survival; Culture Media; Cyclophosphamide; Cytarabine; Deoxycytidine; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Neoplastic Stem Cells; Phytohemagglutinins; Suspensions; Tumor Cells, Cultured

1990
Distribution of kinase and deaminase of 1-beta-D-arabinofuranosylcytosine in tissues of man and mouse.
    Cancer research, 1973, Volume: 33, Issue:11

    Topics: Aminohydrolases; Animals; Bone Marrow; Bone Marrow Cells; Cytarabine; Deoxycytidine; Humans; Kidney; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Liver; Mice; Phosphotransferases; Spleen; Uridine

1973