deoxycytidine has been researched along with Cancer of Head in 113 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (13.27) | 18.2507 |
| 2000's | 53 (46.90) | 29.6817 |
| 2010's | 43 (38.05) | 24.3611 |
| 2020's | 2 (1.77) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, WC; Chiu, CF; Hsieh, CY; Hua, CH; Lien, MY; Lin, CC; Lin, CY; Lo, WJ | 1 |
| Feng, W; Hong, H; Huang, X; Jiang, W; Li, Z; Liang, J; Liang, L; Liu, Q; Liu, Y; Liu, ZG; Peng, Y; Xian, S; Yang, S; Zhang, Y; Zhang, Z; Zhong, G; Zhou, Y | 1 |
| Bartscht, T; Hakim, SG; Idel, C; Rades, D | 1 |
| Argenone, A; Caponigro, F; Daponte, A; Fulciniti, F; Ionna, F; Longo, F; Muto, P; Perri, F; Sandomenico, F | 1 |
| Barik, S; Gupta, S; Khan, H; Negi, MP | 1 |
| Albini, A; Banzi, M; Boni, C; Casali, B; Farnetti, E; Focaccetti, C; Magnani, E; Nicoli, D; Savoldi, L | 1 |
| Barker, C; Lee, L; Mais, K; McPartlin, AJ; Mitchell, K; Slevin, NJ; Swindell, R; Sykes, A; Yap, B | 1 |
| Clark, JI; Kucuk, O; Malhotra, B; Moon, J; Urba, SG; Wolf, GT; Worden, FP | 1 |
| Bank, PC; Guchelaar, HJ; Swen, JJ | 1 |
| Chen, YW; Chou, KM; Chu, P; Liu, X; Loria, S; Wang, Y; Yen, Y; Zhou, W | 1 |
| Hirakawa, K; Kashiwagi, S; Kawajiri, H; Noda, S; Onoda, N; Takashima, T | 1 |
| Fujisawa, T; Han, J; Husain, SR; Puri, RK | 1 |
| Chen, EY; Eastman, A; Hodge, S; Hou, H; Khan, N; Kuppusamy, M; Kuppusamy, P; Swartz, HM | 1 |
| Cui, L; Ji, SL; Xiong, L; Zhang, CY; Zheng, HL; Zhu, MH | 1 |
| Konda, S; O'Bryan, KW; Patel, VA; Ratner, D | 1 |
| Benasso, M; Merlano, MC; Peeters, M; Specenier, P; Szturz, P; Van den Weyngaert, D; Van Gestel, D; Van Laer, C; Vanderveken, OM; Vermorken, J; Wouters, K | 1 |
| Chang, CL; Chen, JH; Chen, TM; Lai, MT; Lee, FP; Lin, KC; Wu, CC; Wu, SY; Yen, YC; Yuan, KS | 1 |
| Akita, H; Hokari, M; Iwasaki, Y; Kamoshima, Y; Sawamura, Y | 1 |
| Awada, A; Bernier, J; Bogaerts, J; Buter, J; de Mulder, P; Lacombe, D; Licitra, L; Locati, LD; Thomas, J; van Herpen, CM; Vermorken, JB | 1 |
| Khan, K; Li, D; Li, G; O'Malley, BW; Rhee, J; Ronson, S; Saito, K; Suntharalingam, M; Van Echo, D; Yu, SZ | 1 |
| Chauhan, A; Manocha, KK; Sharma, T; Singh, H | 1 |
| Chang, PM; Chang, SY; Chen, PM; Chu, PY; Huang, JL; Tai, SK; Tsai, TL; Tzeng, CH; Wang, HM; Wang, YF; Yang, MH | 1 |
| Balducci, M; D'Agostino, GR; Dinapoli, N; Mantini, G; Massaccesi, M; Mattiucci, GC; Meduri, B; Micciché, F; Nardone, L; Salvi, G; Valentini, V | 1 |
| Levine, PA; Petroni, G; Read, P; Reibel, J; Thomas, CY | 1 |
| Altintas, S; Huizing, MT; Specenier, PM; Van den Brande, J; Van den Weyngaert, D; Van Laer, C; Vermorken, JB; Weyler, J | 1 |
| Bhupalam, L; Kloecker, GH; Laber, DA; Miller, DM; Rabinowits, G | 1 |
| Adansa, JC; Cruz, JJ; Gil-Arnaiz, I; Hitt, R; Irigoyen, A; Isla, D; Lambea, J; Lecumberri, MJ; Martinez-Trufero, J | 1 |
| Foster, J; Lee, J; Urba, S; Worden, F; Zhang, J | 1 |
| Ahn, MJ; Do, IG; Ko, YH; Park, K; Park, YH; Won, YW | 1 |
| Baay, M; Lambrechts, HA; Lardon, F; Meijnders, P; Pattyn, GG; Pauwels, B; Vermorken, JB; Wouters, A | 1 |
| Matouskova, E; Mladkova, J; Sanda, M; Selicharova, I | 1 |
| Bergin, P; Damianovich, D; Findlay, M; Hanning, F; Hill, A; McKeage, MJ; Thompson, P | 1 |
| Aelbrecht, K; De Boeck, G; Dyck, J; Guetens, G; Specenier, P; Van den Weyngaert, D; Vermorken, JB; Weyler, J | 1 |
| Carlson, D; Fury, MG; Haque, S; Pfister, D; Shen, R; Stambuk, H | 1 |
| Birzgalis, A; Homer, J; Jegannathen, A; Lee, L; Mais, K; Ryder, WD; Slevin, N; Sykes, A; Yap, B | 1 |
| Blasiak, J; Bloch, K; Chojnacki, J; Drzewoski, J; Kaczmarczyk, D; Kasznicki, J; Krupa, R; Morawiec-Sztandera, A; Sliwinski, T; Wisniewska-Jarosinska, M | 1 |
| Carron, MA; Kucuk, O; Lin, HS; Shkoukani, MA; Tulunay, O | 1 |
| Sun, Q; Yu, J; Zhang, L; Zheng, X | 1 |
| Abo-Elyazeed, A; El-Hadaad, HA; Halim, AA; Wahba, HA | 1 |
| Aguilar Ponce, JL; Cabrera Aquino, G; Chilaca Rosas, MF; Frías Mendivil, M; Granados García, M; Lavín Lozano, AJ; Maldonado Magos, F; Montes Luis, MM; Olvera Caraza, D; Segura Pacheco, BA | 1 |
| Beniwal, P; Blair, EA; Cohen, EEW; Dekker, AJ; Gomez-Abuin, G; Haraf, D; Kocherginsky, M; Langerman, A; Portugal, L; Salama, JK; Seiwert, T; Stenson, KM; Villaflor, VM; Vokes, EE; Williams, RD; Witt, ME | 1 |
| Afonso, SL; da Silva, LG; Stefano, EJ; Tavares, VC; Viani, GA | 1 |
| Afrin, LB; Bielawski, J; Bostick, R; Chaudhary, U; Day, TA; Garrett-Mayer, E; Gillespie, MB; Hannun, YA; O'Brien, PE; Ogretmen, B; Saddoughi, SA; Senkal, CE; Sharma, AK; Shirai, K; Simon, GR; Wilhoit, CS | 1 |
| Abdelraheem, AG; Ali, EM | 1 |
| Kornek, G; Lemaire, C; Radonjic, D; Selzer, E; Vormittag, L | 1 |
| Colantonio, I; Comino, A; Crook, T; Denaro, N; Gasco, M; Lattanzio, L; Lo Nigro, C; Merlano, M; Monteverde, M; Natoli, G; Russi, E; Syed, N; Vivenza, D | 1 |
| Aiba, S; Fujimura, T; Haga, T; Hashimoto, A; Hidaka, T; Mizuashi, M; Onami, K; Watabe, A | 1 |
| El Deen, DA; El Morsy, SM; Toson, EA | 1 |
| Chen, XQ; Li, YJ; Wang, KF; Wang, L; Wang, ZH; Xia, YF; Xia, ZJ | 1 |
| Ceruse, P; Fayette, J; Girodet, D; Péron, J; Poupart, M; Ramade, A; Zrounba, P | 1 |
| Aguilar-Ponce, JL; Alvarez-Avitia, MA; Arrieta, O; Castillo-Hernández, C; Cruz López, JC; De la Garza-Salazar, J; González-Ramírez, I; Granados-García, M; Lara-Cruz, G; Maldonado-Magos, F; Martinez-Juárez, I; Medina-Santillan, R | 1 |
| Needle, MN | 1 |
| Dudley, E; El-Sharkawi, S; Esmans, EL; Games, DE; Langridge, JI; Lemiere, F; Newton, RP; Van Dongen, W | 1 |
| Ameye, G; Cedervall, B; Grégoire, V; Libouton, JM; Michaux, L; Octave-Prignot, M; Rosier, JF; Scalliet, P; Verellen-Dumoulin, C | 1 |
| Chamorey, E; Giroux, B; Guardiola, E; Magné, N; Milano, G; Mouri, Z; Otto, J; Pivot, X; Schneider, M; Thyss, A | 1 |
| Ciccolini, J; Dubreuil, A; Etienne, MC; Fischel, JL; Formento, JL; Formento, P; Magné, N; Marchetti, S; Milano, G; Renée, N; Tiffon, C | 1 |
| Aguilar-Ponce, J; Alvarado, A; Castillo-Henkel, C; De la Garza, J; Dueñas-González, A; Granados-García, M; Green, D; Herrera-Gómez, A; Luna-Ortiz, K; Martínez-Said, H; Poitevin-Chacón, A; Segura-Pacheco, B; Villavicencio, V | 1 |
| Benasso, M; Corvò, R; Pallestrini, E; Ponzanelli, A; Ricci, I; Rosso, R; Sanguineti, G; Santelli, A; Vitale, V | 1 |
| Beauduin, M; Bruniaux, M; Grégoire, V; Husson, B; Octave-Prignot, M; Rosier, JF | 1 |
| Argiris, A; Eng, C; Haraf, DJ; Kozloff, MF; Milano, MT; Mittal, BB; Pelzer, H; Stenson, KM; Vokes, EE; Witt, ME | 1 |
| Airoldi, M; Cagliero, E; Cattel, L; Goffredo, F; Passera, R; Stella, B | 1 |
| Balm, AJ; Damen, E; Eisbruch, A; Marsh, R; Pameijer, FA; Rasch, C; Schwartz, M; Van As, CJ; Vineberg, K | 1 |
| Brandariz, A; Cortés-Funes, H; Hitt, R; Jimeno, A; López-Martín, A; Millán, JM; Peña, C; Rodríguez-Peralto, JL; Rodríguez-Pinilla, M | 1 |
| Argiris, A; Haraf, DJ; Kao, J; Milano, MT; Mittal, BB; Salama, JK; Stenson, KM; Vokes, EE; Weichselbaum, RR; Witt, ME | 1 |
| Bier, J; Gath, HJ; Oettle, H; Raguse, JD; Riess, H | 1 |
| Brodsky, I; Rosenbluth, JZ; Styler, MJ; Zak, D | 1 |
| Chmura, SJ; Haraf, DJ; Kao, J; Milano, MT; Salama, JK; Stenson, KM; Vokes, EE; Witt, ME | 1 |
| Forkert, R; Fronhoffs, S; Ko, Y; Koll, C; Neuhaus, T; Stier, S; Tuohimaa, A; Vetter, H | 1 |
| Baek, JH; Chae, YS; Jeon, SB; Kim, DH; Kim, JC; Kim, JG; Lee, KB; Park, IK; Park, JS; Sohn, JH; Sohn, SK | 1 |
| Gajewski, BJ; Mayo, MS | 1 |
| Chun, PY; Davis, MA; Feng, FY; Lawrence, TS; Nyati, MK; Scheurer, AM | 1 |
| Guo, Y; Hong, XN; Li, J; Tang, WY; Wang, JL | 1 |
| Bielawska, A; Bielawski, J; Cobanoglu, B; Day, TA; Hannun, YA; Koybasi, S; Meyer, M; Obeid, LM; Ogretmen, B; Ponnusamy, S; Rossi, MJ; Senkal, CE; Sinha, D; Sundararaj, K; Szulc, Z | 1 |
| Hennemann, B | 1 |
| Angouridakis, N; Aravantinos, G; Bafaloukos, D; Bamias, A; Christodoulou, C; Dafni, U; Daniilidis, J; Economopoulos, T; Fountzilas, G; Kalofonos, H; Kalogera-Fountzila, A; Karina, M; Makatsoris, T; Maniadakis, N; Nikolaou, A; Papakostas, P; Pavlidis, N; Stathopoulos, G; Syrigos, K | 1 |
| Cipolat, M; Colantonio, I; Di Costanzo, G; Fea, E; Garrone, O; Gasco, M; Granetto, C; Merlano, M; Numico, G; Occelli, M; Pelissero, A; Russi, EG; Sorrentino, R; Taglianti, RV; Vitiello, R | 1 |
| Boswell, JS; Flam, MS; Tashjian, DN; Tschang, TP | 1 |
| Bentzen, JD; Hansen, HS | 1 |
| Bialewski, J; Hannun, YA; Jazwinski, SM; Jiang, JC; Ogretmen, B; Ponnusamy, S; Rossi, MJ; Senkal, CE; Sinha, D | 1 |
| Chun, PY; Davis, MA; Feng, FY; Lawrence, TS; Li, X; Lopez, CA; Normolle, DP; Nyati, MK; Varambally, S | 1 |
| Borel, C; Calais, G; Cupissol, D; Eymard, JC; Germann, N; Kohser, F; Labourey, JL; Tourani, JM; Tubiana-Mathieu, N | 1 |
| Azim, HA; Elsedewy, E | 1 |
| Kallistratos, MS; Karabelis, A; Kopterides, P; Kosmas, C; Mylonakis, N; Skopelitis, H; Syrios, J; Tsavaris, N | 1 |
| Dyck, J; Huizing, MT; Schrijvers, D; Specenier, PM; Van den Brande, J; Van den Weyngaert, D; Van Laer, C; Vermorken, JB; Weyler, J | 1 |
| Gu, Y; Guo, Y; Hong, X; Hu, X; Li, J; Tang, W; Wang, B; Wang, J | 1 |
| Bacigalupo, A; Benasso, M; Corvò, R; Marcenaro, M; Margarino, G; Ponzanelli, A; Vigo, V | 1 |
| Erovic, BM; Heiduschka, G; Kloimstein, P; Martinek, H; Selzer, E; Skoda, C; Thurnher, D; Vormittag, L; Wachek, V; Wrba, F | 1 |
| Boven, E; Braakhuis, BJ; Peters, GJ; Ruiz van Haperen, VW; Veerman, G | 1 |
| Bergman, AM; Braakhuis, BJ; Kuiper, CM; Peters, GJ; Ruiz van Haperen, VW; Veerman, G | 1 |
| Bruntsch, U; Catimel, G; Clavel, M; de Mulder, P; Judson, I; Piccart, M; Sessa, C; Vermorken, JB; Verweij, J; Wanders, J | 1 |
| Braakhuis, BJ; Peters, GJ; Ruiz van Haperen, VW; Welters, MJ | 1 |
| Eisbruch, A; Lawrence, TS; Shewach, DS | 1 |
| Devriendt, D; Klastersky, J | 1 |
| Athanassiades, A; Bacoyiannis, C; Briassoulis, E; Fountzilas, G; Kalogera-Fountzila, A; Kosmidis, P; Pavlidis, N; Samantas, E; Skarlos, D | 1 |
| Alvarez Vincent, JJ; Brandariz, A; Castellano, D; Cortés-Funes, H; García-Carbonero, R; Hidalgo, M; Hitt, R; Millán, JM; Peña, M | 1 |
| Ferguson, PJ; Hammond, JR; Lee, S | 1 |
| Beauduin, M; Bruniaux, M; de Bast, M; de Coster, B; Grégoire, V; Octave-Prignot, M; Rosier, JF; Scalliet, P | 1 |
| Bacoyiannis, C; Daniilidis, J; Fountzilas, G; Kalofonos, H; Kalogera-Fountzila, A; Kosmidis, P; Nicolaides, C; Nikolaou, A; Papadimitriou, C; Pavlidis, N; Samantas, E; Stathopoulos, G | 1 |
| Khattab, J; Urba, SG | 1 |
| Eisbruch, A; Fields, MT; Lawrence, TS; McGinn, CJ; Shewach, DS | 1 |
| Bergman, AM; Kroep, JR; Peters, GJ; Pinedo, HM; Ruiz van Haperen, VW; van Moorsel, CJ; Veerman, G; Voorn, DA | 1 |
| Davis, MA; Eisbruch, A; Fields, MT; Lawrence, TS; Normolle, D; Orfali, A; Pu, AT | 1 |
| Glisson, BS; Hong, WK; Khuri, FR; Lippman, SM; Shin, DM | 1 |
| Lewis, NL; Meropol, NJ | 1 |
| Bradford, CR; Chepeha, DB; Dawson, LA; Eisbruch, A; Hogikyan, ND; Lawrence, TS; Littles, JF; Marentette, LJ; Shewach, DS; Teknos, TN; Terrell, JE; Urba, S; Wolf, GT | 1 |
| Davis, MA; Hough, A; Lawrence, TS; Rehemtulla, A | 1 |
| Ensley, JF; Giguere, JK; Gundacker, H; Kuebler, JP; Mills, GM; Samlowski, WE; Schuller, DE | 1 |
| Allegretto, M; Mackey, JR; Selkaly, H | 1 |
| Benasso, M; Corvò, R; Marchetti, G; Merlano, M; Numico, G; Pallestrini, E; Ricci, I; Rosso, R; Sanguineti, G; Santelli, A; Vitale, V | 1 |
| Robbins, KT | 1 |
| Bradford, CR; Chepeha, DB; Dawson, LA; Eisbruch, A; Haxer, MJ; Hogikyan, ND; Lyden, T; Miller, AE; Teknos, TN; Terrell, JE; Wolf, GT | 1 |
| Noordhuis, P; Peters, GJ; Ruiz van Haperen, VW; Veerman, G; Vermorken, JB | 1 |
| Braakhuis, BJ; Snow, GB; van Dongen, GA; Vermorken, JB | 1 |
11 review(s) available for deoxycytidine and Cancer of Head
| Article | Year |
|---|---|
Gemcitabine-Based Chemoradiation in the Treatment of Locally Advanced Head and Neck Cancer: Systematic Review of Literature and Meta-Analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Deoxycytidine; Gemcitabine; Head and Neck Neoplasms; Humans; Neoplasm Recurrence, Local; Radiation-Sensitizing Agents; Radiotherapy, Intensity-Modulated; Squamous Cell Carcinoma of Head and Neck | 2016 |
Safety experience with IMC-C225, an anti-epidermal growth factor receptor antibody.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Cisplatin; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Drug Eruptions; Drug Hypersensitivity; Drug Interactions; Gemcitabine; Head and Neck Neoplasms; Humans; Irinotecan; Pancreatic Neoplasms | 2002 |
Combination of gemcitabine and irinotecan for recurrent metastatic osteogenic sarcoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Cisplatin; Combined Modality Therapy; Deoxycytidine; Doxorubicin; Etoposide; Femoral Neoplasms; Gemcitabine; Head and Neck Neoplasms; Humans; Ifosfamide; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Palliative Care; Salvage Therapy; Scalp; Skin Neoplasms; Thoracotomy | 2005 |
[Palliative chemotherapy of head and neck cancer: present status and future development].
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Deoxycytidine; Disease Progression; ErbB Receptors; Forecasting; Gefitinib; Gemcitabine; Head and Neck Neoplasms; Humans; Neoplasm Metastasis; Neoplasm Recurrence, Local; Palliative Care; Patient Selection; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Rats; Taxoids; Time Factors; Treatment Outcome; Vinblastine; Vinorelbine | 2006 |
Imatinib in the treatment of follicular dendritic sarcoma: a case report and review of literature.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biomarkers, Tumor; Cisplatin; Dendritic Cells, Follicular; Deoxycytidine; Follow-Up Studies; Gemcitabine; Head and Neck Neoplasms; Humans; Imatinib Mesylate; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Piperazines; Positron-Emission Tomography; Proto-Oncogene Proteins c-kit; Pyrimidines; Sarcoma; Tomography, X-Ray Computed; Treatment Outcome | 2007 |
Gemcitabine-mediated radiosensitization.
Topics: Carcinoma, Squamous Cell; Clinical Trials, Phase I as Topic; Colonic Neoplasms; Deoxycytidine; Gemcitabine; Head and Neck Neoplasms; Humans; Radiation-Sensitizing Agents; Research Design; Tumor Cells, Cultured | 1997 |
New cytostatic agents for the treatment of head and neck cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Clinical Trials, Phase III as Topic; Deoxycytidine; Docetaxel; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Ifosfamide; Paclitaxel; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant; Taxoids | 1997 |
Chemotherapy in head and neck cancer. Overview of newer agents.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Docetaxel; Gemcitabine; Head and Neck Neoplasms; Humans; Organoplatinum Compounds; Paclitaxel; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant; Taxoids; Topotecan; Vinblastine; Vinorelbine | 1999 |
Radiosensitization by gemcitabine.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Cycle; Combined Modality Therapy; Deoxycytidine; Enzyme Inhibitors; Gemcitabine; Head and Neck Neoplasms; Humans; Lung Neoplasms; Neoplasms; Pancreatic Neoplasms; Radiation-Sensitizing Agents; Ribonucleotide Reductases | 1999 |
Treatment of patients with recurrent or metastatic squamous cell carcinoma of the head and neck: current status and future directions.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Deoxycytidine; Docetaxel; Gemcitabine; Head and Neck Neoplasms; Humans; Ifosfamide; Neoplasm Recurrence, Local; Paclitaxel; Taxoids; Vinblastine; Vinorelbine | 2000 |
Oral fluoropyrimidines in cancer treatment.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Head and Neck Neoplasms; Humans; Lung Neoplasms; Neoplasms; Pyridines; Stomach Neoplasms; Tegafur; Uracil | 2000 |
47 trial(s) available for deoxycytidine and Cancer of Head
| Article | Year |
|---|---|
Rituximab in combination with gemcitabine plus cisplatin in patients with recurrent and metastatic head and neck squamous cell carcinoma: a phase I trial.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Feasibility Studies; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects; Rituximab; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2022 |
Neoadjuvant toripalimab combined with gemcitabine and cisplatin in resectable locally advanced head and neck squamous cell carcinoma (NeoTGP01): An open label, single-arm, phase Ib clinical trial.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Gemcitabine; Head and Neck Neoplasms; Humans; Immune Checkpoint Inhibitors; Neoadjuvant Therapy; Programmed Cell Death 1 Receptor; Receptors, Death Domain; Squamous Cell Carcinoma of Head and Neck | 2022 |
Induction chemotherapy with docetaxel, cisplatin and capecitabine, followed by combined cetuximab and radiotherapy in patients with locally advanced inoperable squamous cell carcinoma of the head and neck: a phase I-II study.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Squamous Cell; Cetuximab; Chemoradiotherapy; Cisplatin; Deoxycytidine; Docetaxel; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Induction Chemotherapy; Male; Maximum Tolerated Dose; Middle Aged; Squamous Cell Carcinoma of Head and Neck; Taxoids; Treatment Outcome | 2013 |
Clinical benefits of concurrent capecitabine and cisplatin versus concurrent cisplatin and 5-flurouracil in locally advanced squamous cell head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Squamous Cell; Chemoradiotherapy, Adjuvant; Cisplatin; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Grading; Neoplasm Invasiveness; Neoplasm Staging; Quality of Life | 2013 |
Phase II trial of biweekly gemcitabine and paclitaxel with recurrent or metastatic squamous cell carcinoma of the head and neck: Southwest Oncology Group study S0329.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Feasibility Studies; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2014 |
Phase II study on gemcitabine in recurrent and/or metastatic adenoid cystic carcinoma of the head and neck (EORTC 24982).
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Adenoid Cystic; Deoxycytidine; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Recurrence, Local; Patient Compliance; Treatment Outcome | 2008 |
Gemcitabine concurrent with radiation therapy for locally advanced head and neck carcinomas.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Prospective Studies; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant; Treatment Outcome | 2008 |
Promising overall survival of patients with recurrent/metastatic squamous cell carcinoma of head and neck receiving gemcitabine plus cisplatin treatment: report of a multi-center phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Deoxycytidine; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis | 2010 |
Phase I study of capecitabine, carboplatin and intensity-modulated radiation therapy for head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carboplatin; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Head and Neck Neoplasms; Humans; Treatment Outcome | 2009 |
Fixed-dose every-other-week capecitabine and oxaliplatin for refractory squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Capecitabine; Carcinoma, Squamous Cell; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Pilot Projects | 2010 |
Phase II study of capecitabine as palliative treatment for patients with recurrent and metastatic squamous head and neck cancer after previous platinum-based treatment.
Topics: Adult; Aged; Capecitabine; Carcinoma, Squamous Cell; Deoxycytidine; Disease Progression; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Palliative Care; Platinum Compounds | 2010 |
A phase II trial evaluating weekly docetaxel and capecitabine in patients with metastatic or advanced, locally recurrent head and neck cancers.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Case-Control Studies; Deoxycytidine; Disease-Free Survival; Docetaxel; Drug Administration Schedule; Fatigue; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Lymphopenia; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Taxoids; Treatment Outcome | 2010 |
A phase II study of combination chemotherapy with capecitabine and cisplatin in patients with metastatic or recurrent squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Squamous Cell; Cisplatin; Deoxycytidine; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Immunohistochemistry; Male; Middle Aged; Neoplasm Metastasis; Recurrence | 2011 |
A phase 2 study of pemetrexed plus gemcitabine every 2 weeks for patients with recurrent or metastatic head and neck squamous cell cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Squamous Cell; Deoxycytidine; Drug Administration Schedule; Female; Gemcitabine; Glutamates; Guanine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasms, Squamous Cell; Pemetrexed; Recurrence; Squamous Cell Carcinoma of Head and Neck | 2011 |
Synchronous chemoradiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck using capecitabine: a single-centre, open-label, single-group phase II study.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma; Carcinoma, Squamous Cell; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Dose Fractionation, Radiation; Female; Fluorouracil; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Staging; Neoplasms, Squamous Cell; Squamous Cell Carcinoma of Head and Neck; Survival Analysis; Treatment Outcome | 2011 |
Concomitant chemoradiotherapy using low-dose weekly gemcitabine versus low-dose weekly paclitaxel in locally advanced head and neck squamous cell carcinoma: a phase III study.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemoradiotherapy; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Paclitaxel; Young Adult | 2012 |
Cetuximab concomitant with gemcitabine and radiotherapy in advanced squamous cell carcinomas of upper aerodigestive tract: a pilot study.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Combined Modality Therapy; Deoxycytidine; Disease Progression; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Pilot Projects; Radiotherapy, Adjuvant; Survival Analysis; Treatment Outcome | 2011 |
Phase II trial of pemetrexed-based induction chemotherapy followed by concomitant chemoradiotherapy in previously irradiated patients with squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Deoxycytidine; Female; Gemcitabine; Glutamates; Guanine; Head and Neck Neoplasms; Humans; Induction Chemotherapy; Male; Middle Aged; Neoplasm Recurrence, Local; Pemetrexed; Prospective Studies; Radiotherapy; Squamous Cell Carcinoma of Head and Neck | 2011 |
Weekly gemcitabine and cisplatin in combination with radiotherapy in patients with locally advanced head-and-neck cancer: Phase I study.
Topics: Aged; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Deoxycytidine; Dose Fractionation, Radiation; Drug Administration Schedule; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Prospective Studies; Radiation-Sensitizing Agents; Radiodermatitis; Radiotherapy, Conformal; Remission Induction; Stomatitis | 2011 |
Results of a phase II trial of gemcitabine plus doxorubicin in patients with recurrent head and neck cancers: serum C₁₈-ceramide as a novel biomarker for monitoring response.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Carcinoma, Squamous Cell; Ceramides; Deoxycytidine; Doxorubicin; Gemcitabine; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Middle Aged; Recurrence; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2011 |
Concurrent radiotherapy and chemotherapy for locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Prospective Studies; Radiation-Sensitizing Agents; Young Adult | 2011 |
Re-irradiation combined with capecitabine in locally recurrent squamous cell carcinoma of the head and neck. A prospective phase II trial.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma, Squamous Cell; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Mucositis; Neoplasm Recurrence, Local; Radiotherapy; Squamous Cell Carcinoma of Head and Neck; Survival Analysis; Treatment Outcome; Young Adult | 2012 |
Gemcitabine-based induction chemotherapy and concurrent with radiation in advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Induction Chemotherapy; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging | 2012 |
Phase I and pharmacokinetic study of the association of capecitabine-cisplatin in head and neck cancer patients.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chromatography, High Pressure Liquid; Cisplatin; Deoxycytidine; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Treatment Outcome | 2003 |
Phase II trial of gemcitabine concurrent with radiation for locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Middle Aged; Radiation Injuries; Ribonucleotide Reductases; Treatment Outcome | 2004 |
Alternating gemcitabine and cisplatin with gemcitabine and radiation in stage IV squamous cell carcinoma of the head and neck.
Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Deoxycytidine; Female; Fever; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Staging; Neoplasms, Squamous Cell; Neutropenia; Survival Analysis; Survival Rate; Thrombocytopenia; Treatment Outcome | 2004 |
Phase I study of concomitant chemoradiotherapy with paclitaxel, fluorouracil, gemcitabine, and twice-daily radiation in patients with poor-prognosis cancer of the head and neck.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Combined Modality Therapy; Deoxycytidine; Disease Progression; Disease-Free Survival; Female; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Metastasis; Paclitaxel; Prognosis; Radiometry; Time Factors; Treatment Outcome | 2004 |
Gemcitabine plus vinorelbine chemotherapy regimens: a pharmacokinetic study of alternate administration sequences.
Topics: Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Drug Administration Schedule; Drug Interactions; Forecasting; Gemcitabine; Half-Life; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Italy; Kinetics; Lymphoma, Non-Hodgkin; Vinblastine; Vinorelbine | 2004 |
Dysphagia and aspiration after chemoradiotherapy for head-and-neck cancer: which anatomic structures are affected and can they be spared by IMRT?
Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Deglutition; Deglutition Disorders; Deoxycytidine; Gemcitabine; Head and Neck Neoplasms; Humans; Hypopharynx; Image Processing, Computer-Assisted; Palatine Tonsil; Pharyngeal Muscles; Pneumonia, Aspiration; Prospective Studies; Radiotherapy, Conformal; Tongue | 2004 |
Phase II trial of cisplatin and capecitabine in patients with squamous cell carcinoma of the head and neck, and correlative study of angiogenic factors.
Topics: Adult; Aged; Angiogenesis Inducing Agents; Antineoplastic Agents; Capecitabine; Carcinoma, Squamous Cell; Cisplatin; Deoxycytidine; Fluorouracil; Head and Neck Neoplasms; Humans; Immunohistochemistry; Male; Middle Aged; Receptors, Vascular Endothelial Growth Factor; Thymidine Phosphorylase; Thymidylate Synthase; Treatment Outcome | 2004 |
Twice-daily reirradiation for recurrent and second primary head-and-neck cancer with gemcitabine, paclitaxel, and 5-fluorouracil chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Paclitaxel; Radiotherapy Dosage | 2005 |
Gemcitabine in the treatment of advanced head and neck cancer.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined Modality Therapy; Deoxycytidine; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Quality of Life; Radiotherapy; Salvage Therapy; Survival Rate; Treatment Outcome | 2005 |
Gemcitabine and paclitaxel in metastatic or recurrent squamous cell carcinoma of the head and neck: a phase I-II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Deoxycytidine; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Paclitaxel | 2005 |
Phase II study of concurrent chemoradiotherapy with capecitabine and cisplatin in patients with locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Capecitabine; Carcinoma, Squamous Cell; Cisplatin; Deoxycytidine; Disease Progression; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Staging; Survival Rate | 2005 |
Paclitaxel and gemcitabine vs. paclitaxel and pegylated liposomal doxorubicin in advanced non-nasopharyngeal head and neck cancer. An efficacy and cost analysis randomized study conducted by the Hellenic Cooperative Oncology Group.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cost-Benefit Analysis; Deoxycytidine; Doxorubicin; Female; Gemcitabine; Greece; Head and Neck Neoplasms; Humans; Male; Middle Aged; Paclitaxel; Patient Compliance; Polyethylene Glycols; Survival Analysis; Treatment Outcome | 2006 |
Phase II analysis of paclitaxel and capecitabine in the treatment of recurrent or disseminated squamous cell carcinoma of the head and neck region.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Treatment Outcome | 2007 |
Docetaxel plus gemcitabine in recurrent and/or metastatic squamous cell carcinoma of the head and neck: a phase II multicenter study.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Deoxycytidine; Docetaxel; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Middle Aged; Pharyngeal Neoplasms; Recurrence; Taxoids; Treatment Outcome | 2007 |
Phase II feasibility study of concurrent radiotherapy and gemcitabine in chemonaive patients with squamous cell carcinoma of the head and neck: long-term follow up data.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Feasibility Studies; Female; Follow-Up Studies; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Radiotherapy Dosage; Radiotherapy, Adjuvant; Risk Assessment; Survival Analysis; Time Factors | 2007 |
A phase II trial of low-dose gemcitabine and radiation alternated to cisplatin and 5-fluorouracil: an active and manageable regimen for stage IV squamous cell carcinoma of the head and neck.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Survival Rate; Treatment Outcome | 2008 |
A phase II study of Gemcitabine (LY 188011) in patients with advanced squamous cell carcinoma of the head and neck. EORTC Early Clinical Trials Group.
Topics: Adult; Aged; Alanine Transaminase; Antimetabolites, Antineoplastic; Aspartate Aminotransferases; Carcinoma, Squamous Cell; Deoxycytidine; Europe; Fatigue; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Liver; Male; Middle Aged; Neutropenia; Remission Induction | 1994 |
Paclitaxel in combination with carboplatin or gemcitabine for the treatment of advanced head and neck cancer.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Deoxycytidine; Drug Administration Schedule; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Immunosuppression Therapy; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Paclitaxel | 1997 |
Phase II trial of cisplatin and gemcitabine in advanced squamous-cell carcinoma of the head and neck.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asthenia; Bone Marrow Diseases; Carcinoma, Squamous Cell; Combined Modality Therapy; Deoxycytidine; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Salvage Therapy; Treatment Outcome | 1998 |
Paclitaxel and gemcitabine in advanced non-nasopharyngeal head and neck cancer: a phase II study conducted by the Hellenic Cooperative Oncology Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Deoxycytidine; Drug Administration Schedule; Female; Gemcitabine; Greece; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Middle Aged; Paclitaxel; Prognosis; Survival Rate | 1999 |
Radiation concurrent with gemcitabine for locally advanced head and neck cancer: a phase I trial and intracellular drug incorporation study.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biopsy; Combined Modality Therapy; Cytosine Nucleotides; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Radiation-Sensitizing Agents; Radiotherapy | 2001 |
Evaluation of gemcitabine in patients with recurrent or metastatic squamous cell carcinoma of the head and neck: a Southwest Oncology Group phase II study.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Deoxycytidine; Drug Evaluation; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Ribonucleotide Reductases; Survival Rate | 2001 |
Gemcitabine, cisplatin, and radiation in advanced, unresectable squamous cell carcinoma of the head and neck: a feasibility study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Deoxycytidine; Dose Fractionation, Radiation; Feasibility Studies; Female; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Remission Induction; Survival Analysis | 2001 |
Objective assessment of swallowing dysfunction and aspiration after radiation concurrent with chemotherapy for head-and-neck cancer.
Topics: Combined Modality Therapy; Deglutition; Deglutition Disorders; Deoxycytidine; Fluoroscopy; Gemcitabine; Head and Neck Neoplasms; Humans; Pneumonia, Aspiration; Prospective Studies; Radiation-Sensitizing Agents | 2002 |
55 other study(ies) available for deoxycytidine and Cancer of Head
| Article | Year |
|---|---|
Re-irradiation with 36 Gy (1.5 Gy Twice Daily) Plus Paclitaxel for Advanced Recurrent and Previously Irradiated SCCHN is Feasible.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Chemoradiotherapy; Deoxycytidine; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Neoplasm Recurrence, Local; Paclitaxel; Re-Irradiation; Squamous Cell Carcinoma of Head and Neck | 2018 |
Fluoropyrimidine toxicity in patients with dihydropyrimidine dehydrogenase splice site variant: the need for further revision of dose and schedule.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Capecitabine; Colonic Neoplasms; Deoxycytidine; Dihydropyrimidine Dehydrogenase Deficiency; Dose-Response Relationship, Drug; Fluorouracil; Head and Neck Neoplasms; Heterozygote; Humans; Male; Mutation; Patient Selection; Polymerase Chain Reaction | 2013 |
Cisplatin plus capecitabine as first-line chemotherapy for recurrent or metastatic head and neck squamous cell cancer: experience outside of a trial setting.
Topics: Adult; Aged; Antineoplastic Agents; Capecitabine; Carcinoma, Squamous Cell; Cisplatin; Deoxycytidine; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neutropenia; Recurrence; Retrospective Studies | 2013 |
Fluoropyrimidine toxicity in patients with dihydropyrimidine dehydrogenase (DPD) splice site variant: the need for further revision of dose and schedule.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Colonic Neoplasms; Deoxycytidine; Dihydropyrimidine Dehydrogenase Deficiency; Fluorouracil; Head and Neck Neoplasms; Humans; Male | 2014 |
Expression of DNA translesion synthesis polymerase η in head and neck squamous cell cancer predicts resistance to gemcitabine and cisplatin-based chemotherapy.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Deoxycytidine; DNA-Directed DNA Polymerase; Drug Resistance, Neoplasm; Epithelial Cells; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Male; Middle Aged; Prognosis; Squamous Cell Carcinoma of Head and Neck | 2013 |
[A case of metastatic breast carcinoma of the cervical muscles].
Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Carcinoma, Lobular; Deoxycytidine; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Middle Aged; Muscle, Skeletal; Stomach Neoplasms | 2013 |
Identification and characterization of cancer stem cells in human head and neck squamous cell carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; CD24 Antigen; Cell Line, Tumor; Cisplatin; Deoxycytidine; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Hyaluronan Receptors; Mice; Mice, Nude; Neoplastic Stem Cells | 2014 |
Recurrent low-dose chemotherapy to inhibit and oxygenate head and neck tumors.
Topics: Animals; Antineoplastic Agents; Deoxycytidine; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Gemcitabine; Head and Neck Neoplasms; Heterografts; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Oxygen | 2014 |
DNA microarray reveals ZNF195 and SBF1 are potential biomarkers for gemcitabine sensitivity in head and neck squamous cell carcinoma cell lines.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Deoxycytidine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gemcitabine; Head and Neck Neoplasms; Humans; Intracellular Signaling Peptides and Proteins; Kruppel-Like Transcription Factors; Oligonucleotide Array Sequence Analysis; Treatment Outcome; Zinc Fingers | 2014 |
Fibrohistiocytic tumors in a lung transplant patient taking oral capecitabine for nonmelanoma skin cancer chemoprevention.
Topics: Acitretin; Aged; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Deoxycytidine; Fatal Outcome; Fluorouracil; Graft vs Host Disease; Head and Neck Neoplasms; Histiocytoma, Malignant Fibrous; Humans; Keratolytic Agents; Lung Transplantation; Male; Skin Neoplasms | 2014 |
Survival prognostic factors for metachronous second primary head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Deoxycytidine; Docetaxel; Female; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neoplasms, Second Primary; Paclitaxel; Prognosis; Squamous Cell Carcinoma of Head and Neck; Survival Analysis; Taxoids; Treatment Outcome; Young Adult | 2017 |
Craniocervical paraganglioma with numerous pulmonary metastases--case report.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cervical Vertebrae; Combined Modality Therapy; Deoxycytidine; Gemcitabine; Glomus Jugulare Tumor; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Paclitaxel; Paraganglioma; Treatment Outcome | 2008 |
The predictive and therapeutic value of thymidine phosphorylase and dihydropyrimidine dehydrogenase in capecitabine (Xeloda)-based chemotherapy for head and neck cancer.
Topics: Animals; Biomarkers, Tumor; Capecitabine; Carcinoma, Squamous Cell; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Enzyme-Linked Immunosorbent Assay; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Predictive Value of Tests; Regression Analysis; Reverse Transcriptase Polymerase Chain Reaction; Statistics, Nonparametric; Thymidine Phosphorylase; Tumor Cells, Cultured | 2009 |
Low-dose hyperradiosensitivity: is there a place for future investigation in clinical settings?
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Cisplatin; Combined Modality Therapy; Deoxycytidine; Disease Progression; Esophageal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Glutamates; Guanine; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasms; Palliative Care; Pemetrexed; Prospective Studies; Radiation Tolerance; Radiotherapy Dosage; Young Adult | 2010 |
A non-randomized comparison of gemcitabine-based chemoradiation with or without induction chemotherapy for locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cisplatin; Cohort Studies; Combined Modality Therapy; Deoxycytidine; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Metastasis; Proportional Hazards Models; Radiation-Sensitizing Agents; Treatment Outcome | 2009 |
In vitro study on the schedule-dependency of the interaction between pemetrexed, gemcitabine and irradiation in non-small cell lung cancer and head and neck cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Cycle; Cell Proliferation; Combined Modality Therapy; Deoxycytidine; Drug Interactions; Drug Synergism; Flow Cytometry; Gemcitabine; Glutamates; Guanine; Head and Neck Neoplasms; Humans; In Vitro Techniques; Lung Neoplasms; Pemetrexed; Radiotherapy Dosage; Tumor Cells, Cultured | 2010 |
Phenotyping breast cancer cell lines EM-G3, HCC1937, MCF7 and MDA-MB-231 using 2-D electrophoresis and affinity chromatography for glutathione-binding proteins.
Topics: Adult; Aged; Alcohol Oxidoreductases; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Breast Neoplasms; Capecitabine; Carboplatin; Case-Control Studies; Chromatography, Affinity; Cisplatin; Colorectal Neoplasms; Deoxycytidine; Electrophoresis, Gel, Two-Dimensional; Female; Fluorouracil; Glutathione S-Transferase pi; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Neurophysiology; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Phenotype; Survival Rate; Treatment Outcome | 2010 |
Detecting acute neurotoxicity during platinum chemotherapy by neurophysiological assessment of motor nerve hyperexcitability.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carboplatin; Cisplatin; Colorectal Neoplasms; Deoxycytidine; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Motor Neuron Disease; Neoplasm Staging; Neurophysiology; Neurotoxicity Syndromes; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Retrospective Studies; Survival Rate; Treatment Outcome | 2010 |
Difluorodeoxyuridine plasma concentrations after low-dose gemcitabine during chemoradiation in head and neck cancer patients.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Deoxycytidine; Dose-Response Relationship, Drug; Female; Floxuridine; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Radiation-Sensitizing Agents | 2011 |
Cytotoxicity and genotoxicity of capecitabine in head and neck cancer and normal cells.
Topics: Capecitabine; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Survival; Comet Assay; Deoxycytidine; DNA Damage; DNA Repair; DNA Repair Enzymes; DNA, Circular; Drug Screening Assays, Antitumor; Fluorouracil; Head and Neck Neoplasms; Humans; Lymphocytes; Mutagens; Neoplasms, Squamous Cell; Plasmids; Spin Labels; Time Factors | 2011 |
Angiosarcoma of the scalp with complete response to a biweekly gemcitabine and docetaxel (GEMDOC) chemotherapy regimen.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Docetaxel; Female; Gemcitabine; Head and Neck Neoplasms; Hemangiosarcoma; Humans; Scalp; Skin Neoplasms; Taxoids | 2011 |
Smac modulates chemosensitivity in head and neck cancer cells through the mitochondrial apoptotic pathway.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Biomimetic Materials; Blotting, Western; Caspase 3; Cell Line, Tumor; Cytochromes c; Deoxycytidine; Drug Synergism; Enzyme Activation; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Nude; Mitochondria; Mitochondrial Proteins; RNA Interference; Signal Transduction; Xenograft Model Antitumor Assays | 2011 |
MDM2 309 polymorphism predicts outcome in platinum-treated locally advanced head and neck cancer.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cetuximab; Cisplatin; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Gemcitabine; Genes, p53; Head and Neck Neoplasms; Humans; Male; Middle Aged; Mutation; Paclitaxel; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Prognosis; Proto-Oncogene Proteins c-mdm2; Treatment Outcome; Young Adult | 2012 |
Successful treatment of HER-2-positive metastatic apocrine carcinoma of the skin with lapatinib and capecitabine.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Capecitabine; Carcinoma; Deoxycytidine; Fluorouracil; Head and Neck Neoplasms; Humans; Immunohistochemistry; Lapatinib; Liver Neoplasms; Male; Middle Aged; Quinazolines; Receptor, ErbB-2; Scalp; Skin Neoplasms; Time Factors; Tomography, X-Ray Computed; Treatment Outcome | 2012 |
First-line combination of gemcitabine, oxaliplatin, and L-asparaginase (GELOX) followed by involved-field radiation therapy for patients with stage IE/IIE extranodal natural killer/T-cell lymphoma.
Topics: Adult; Aged; Aluminum Hydroxide; Antineoplastic Combined Chemotherapy Protocols; Bentonite; Chemoradiotherapy; Deoxycytidine; Disease-Free Survival; Drug Combinations; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Induction Chemotherapy; Kaplan-Meier Estimate; Lymphoma, Extranodal NK-T-Cell; Magnesium Hydroxide; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Treatment Outcome; Young Adult | 2013 |
Efficacy and safety of capecitabine in heavily pretreated recurrent/metastatic head and neck squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Capecitabine; Carcinoma, Squamous Cell; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Retrospective Studies; Squamous Cell Carcinoma of Head and Neck; Survival Rate | 2012 |
Alternating chemotherapy: gemcitabine and cisplatin with concurrent radiotherapy for treatment of advanced head and neck cancer.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Deglutition Disorders; Deoxycytidine; Disease Progression; Female; Fluorouracil; Follow-Up Studies; Gemcitabine; Head and Neck Neoplasms; Humans; Induction Chemotherapy; Leukopenia; Male; Middle Aged; Neoplasm Staging; Radiation-Sensitizing Agents; Radiodermatitis; Radiotherapy Dosage; Remission Induction; Safety; Stomatitis; Survival Rate; Treatment Outcome; Xerostomia | 2013 |
Analysis of urinary nucleosides. III. Identification of 5'-deoxycytidine in urine of a patient with head and neck cancer.
Topics: Chromatography, High Pressure Liquid; Deoxycytidine; Head and Neck Neoplasms; Humans; Mass Spectrometry | 2003 |
The radioenhancement of two human head and neck squamous cell carcinomas by 2'-2' difluorodeoxycytidine (gemcitabine; dFdC) is mediated by an increase in radiation-induced residual chromosome aberrations but not residual DNA DSBs.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Chromosome Aberrations; Combined Modality Therapy; Deoxycytidine; DNA Damage; DNA, Neoplasm; Gemcitabine; Head and Neck Neoplasms; Humans; Radiation Tolerance; Radiation-Sensitizing Agents; Radiation, Ionizing; Time Factors; Tumor Cells, Cultured | 2003 |
ZD1839 (Iressa) modifies the activity of key enzymes linked to fluoropyrimidine activity: rational basis for a new combination therapy with capecitabine.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Survival; Deoxycytidine; DNA Primers; Floxuridine; Fluorouracil; Gefitinib; Head and Neck Neoplasms; Humans; Models, Chemical; Polymerase Chain Reaction; Pyrimidines; Quinazolines; RNA; RNA, Messenger; Time Factors; Transcription, Genetic | 2003 |
Role of 2'-2' difluorodeoxycytidine (gemcitabine)-induced cell cycle dysregulation in radio-enhancement of human head and neck squamous cell carcinomas.
Topics: Carcinoma, Squamous Cell; Cell Cycle; Deoxycytidine; Flow Cytometry; Gemcitabine; Head and Neck Neoplasms; Humans; Radiation-Sensitizing Agents; Tumor Cells, Cultured | 2004 |
Long-term outcome of concurrent chemotherapy and reirradiation for recurrent and second primary head-and-neck squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Camptothecin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Hydroxyurea; Irinotecan; Male; Mandibular Diseases; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Osteoradionecrosis; Paclitaxel; Prognosis; Radiotherapy Dosage; Treatment Failure; Treatment Outcome | 2006 |
Bayesian sample size calculations in phase II clinical trials using a mixture of informative priors.
Topics: Algorithms; Antineoplastic Agents; Bayes Theorem; Clinical Trials, Phase II as Topic; Computer Simulation; Deoxycytidine; Docetaxel; Gemcitabine; Head and Neck Neoplasms; Humans; Leiomyosarcoma; Organoplatinum Compounds; Oxaliplatin; Sample Size; Taxoids | 2006 |
Synergistic effects of gemcitabine and gefitinib in the treatment of head and neck carcinoma.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Cycle; Deoxycytidine; Drug Administration Schedule; Drug Interactions; ErbB Receptors; Gefitinib; Gemcitabine; Head and Neck Neoplasms; Humans; Quinazolines; Tumor Cells, Cultured | 2006 |
[Experience of gemcitabine plus cisplatin chemotherapy in 52 patients with head and neck cancer].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Deoxycytidine; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Metastasis | 2005 |
Potent antitumor activity of a novel cationic pyridinium-ceramide alone or in combination with gemcitabine against human head and neck squamous cell carcinomas in vitro and in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cations; Cell Line, Tumor; Cell Proliferation; Ceramides; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Head and Neck Neoplasms; Humans; Inactivation, Metabolic; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Mice, SCID; Neoplasms, Squamous Cell; Pyridinium Compounds; Tissue Distribution; Xenograft Model Antitumor Assays | 2006 |
Gemcitabine and cisplatin in a concomitant alternating chemoradiotherapy program for locally advanced head-and-neck cancer: a pharmacology-guided schedule.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Deoxycytidine; Dose Fractionation, Radiation; Drug Administration Schedule; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Middle Aged; Mouth Neoplasms; Neoplasm Recurrence, Local; Neutropenia; Pharyngeal Neoplasms; Stomatitis | 2006 |
Basal cell carcinoma metastatic to cervical lymph nodes and lungs.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy, Fine-Needle; Carboplatin; Carcinoma, Basal Cell; Carcinoma, Papillary; Deoxycytidine; Diagnostic Errors; Docetaxel; Gemcitabine; Head and Neck Neoplasms; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neck Dissection; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Radiotherapy; Seminoma; Skin Neoplasms; Taxoids; Testicular Neoplasms; Thyroid Neoplasms; Thyroidectomy; Unnecessary Procedures | 2006 |
Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Caspases; Cell Line, Tumor; Ceramides; Chromatography, High Pressure Liquid; Chromatography, Liquid; Deoxycytidine; Doxorubicin; Fluorescent Antibody Technique; Gemcitabine; Head and Neck Neoplasms; Humans; Membrane Proteins; Mice; Mice, SCID; Oxidoreductases; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Sphingosine N-Acyltransferase; Survival Rate | 2007 |
Effect of epidermal growth factor receptor inhibitor class in the treatment of head and neck cancer with concurrent radiochemotherapy in vivo.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cetuximab; Combined Modality Therapy; Deoxycytidine; ErbB Receptors; Gefitinib; Gemcitabine; Head and Neck Neoplasms; Mice; Mice, Nude; Quinazolines; Rats; Transplantation, Heterologous | 2007 |
Cardiotoxicity of fluoropyrimidines in different schedules of administration: a prospective study.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Administration Schedule; Electrocardiography; Female; Fluorouracil; Head and Neck Neoplasms; Heart; Heart Diseases; Humans; Infusions, Intravenous; Male; Middle Aged; Prognosis; Prospective Studies | 2008 |
Retrospective case series of gemcitabine plus cisplatin in the treatment of recurrent and metastatic nasopharyngeal carcinoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Retrospective Studies; Survival Rate; Treatment Outcome | 2008 |
Down-regulation of Mcl-1 with antisense technology alters the effect of various cytotoxic agents used in treatment of squamous cell carcinoma of the head and neck.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Blotting, Western; Carcinoma, Squamous Cell; Cell Survival; Cetuximab; Cisplatin; Combined Modality Therapy; Deoxycytidine; Down-Regulation; Fluorouracil; Gemcitabine; Head and Neck Neoplasms; Humans; Immunoenzyme Techniques; Myeloid Cell Leukemia Sequence 1 Protein; Oligonucleotides, Antisense; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 2008 |
Schedule-dependent antitumor effect of gemcitabine in in vivo model system.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma; Carcinoma, Squamous Cell; Colonic Neoplasms; Deoxycytidine; Drug Administration Schedule; Drug Screening Assays, Antitumor; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Sarcoma; Soft Tissue Neoplasms | 1995 |
Interaction between cisplatin and gemcitabine in vitro and in vivo.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cisplatin; Colonic Neoplasms; Deoxycytidine; DNA Damage; DNA, Neoplasm; Drug Administration Schedule; Drug Resistance, Neoplasm; Drug Synergism; Drug Tolerance; Female; Fluorometry; Gemcitabine; Head and Neck Neoplasms; Humans; Injections, Intraperitoneal; Injections, Intravenous; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Tumor Cells, Cultured | 1995 |
Schedule-dependent therapeutic efficacy of the combination of gemcitabine and cisplatin in head and neck cancer xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Deoxycytidine; Drug Administration Schedule; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Transplantation, Heterologous; Tumor Cells, Cultured | 1995 |
[3H]gemcitabine uptake by nucleoside transporters in a human head and neck squamous carcinoma cell line.
Topics: Adenosine Triphosphate; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Carrier Proteins; Deoxycytidine; Drug Resistance; Formycins; Gemcitabine; Head and Neck Neoplasms; Humans; Membrane Proteins; Nucleoside Transport Proteins; Time Factors; Tritium; Tumor Cells, Cultured; Uridine | 1999 |
The effect of 2'-2' difluorodeoxycytidine (dFdC, gemcitabine) on radiation-induced cell lethality in two human head and neck squamous carcinoma cell lines differing in intrinsic radiosensitivity.
Topics: Carcinoma, Squamous Cell; Cell Death; Combined Modality Therapy; Deoxycytidine; Gemcitabine; Head and Neck Neoplasms; Humans; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured | 1999 |
Differential effects of gemcitabine on ribonucleotide pools of twenty-one solid tumour and leukaemia cell lines.
Topics: Animals; Antimetabolites, Antineoplastic; Deoxycytidine; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Leukemia; Lung Neoplasms; Mice; Ovarian Neoplasms; Rats; Ribonucleotide Reductases; Ribonucleotides; Tumor Cells, Cultured | 2000 |
Radiosensitization produced in vivo by once- vs. twice-weekly 2'2'-difluoro-2'-deoxycytidine (gemcitabine).
Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Carcinoma, Squamous Cell; Combined Modality Therapy; Deoxycytidine; Dose-Response Relationship, Radiation; Drug Administration Schedule; Drug Screening Assays, Antitumor; Female; Gemcitabine; Head and Neck Neoplasms; Lip; Mice; Mice, Inbred C3H; Mouth Mucosa; Radiation Tolerance; Radiation-Sensitizing Agents; Weight Loss | 2000 |
The role of apoptosis in 2',2'-difluoro-2'-deoxycytidine (gemcitabine)-mediated radiosensitization.
Topics: Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cell Survival; Cobalt Radioisotopes; Colonic Neoplasms; Coumarins; Deoxycytidine; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Radiation; Electrophoresis, Gel, Pulsed-Field; Enzyme Activation; Gemcitabine; Head and Neck Neoplasms; Humans; Lung Neoplasms; Oligopeptides; Radiation-Sensitizing Agents; Tumor Cells, Cultured | 2001 |
Intraoperative saline and gemcitabine irrigation improves tumour control in human squamous cell carcinoma-contaminated surgical wounds.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Deoxycytidine; Gemcitabine; Head and Neck Neoplasms; Humans; Intraoperative Care; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Seeding; Neoplasm Transplantation; Sodium Chloride; Therapeutic Irrigation; Transplantation, Heterologous; Water | 2001 |
Barriers to winning the battle with head-and-neck cancer.
Topics: Clinical Trials, Phase I as Topic; Deglutition; Deglutition Disorders; Deoxycytidine; Gemcitabine; Head and Neck Neoplasms; Humans; Radiation-Sensitizing Agents | 2002 |
Concentration and time dependent growth inhibition and metabolism in vitro by 2',2'-difluoro-deoxycytidine (gemcitabine).
Topics: Animals; Antimetabolites, Antineoplastic; Biotransformation; Carcinoma, Squamous Cell; Cell Division; Cell Line; Colonic Neoplasms; Deoxycytidine; Drug Screening Assays, Antitumor; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Kinetics; Mice; Ovarian Neoplasms | 1991 |
Preclinical in vivo activity of 2',2'-difluorodeoxycytidine (Gemcitabine) against human head and neck cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Gemcitabine; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Neoplasm Transplantation | 1991 |