deoxycholic-acid has been researched along with Vitamin-A-Deficiency* in 1 studies
1 other study(ies) available for deoxycholic-acid and Vitamin-A-Deficiency
| Article | Year |
|---|---|
[Experimental cancerogenesis. Stimulation of ornithine decarboxylase of the colonic mucosa in vitamin A-deficient rats by sodium desoxycholate].
During a state of pure vitamin A deficiency, without any clinical manifestations, in colonic mucosa: ornithine decarboxylase activity is already stimulated, in deficient animals, by instillation of NaCl 9%. Sodium deoxycholate further enhances and markedly protracts the enzyme activity, as compared to normal rats. These results lead to the conclusion that vitamin A deficiency is a state of special sensibility to the promoter action. Retinol is hence physiologically necessary for natural resistance of intestinal cells against chemically induced tumor promotion. Topics: Animals; Cell Division; Colon; Colonic Neoplasms; Deoxycholic Acid; Enzyme Activation; Intestinal Mucosa; Male; Ornithine Decarboxylase; Rats; Rats, Inbred Strains; Vitamin A Deficiency | 1986 |