demeclocycline and Rhinitis
demeclocycline has been researched along with Rhinitis* in 3 studies
Trials
1 trial(s) available for demeclocycline and Rhinitis
Article | Year |
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Re-evaluation of a randomized controlled trial of antibiotics for minor respiratory illness in general practice.
A systematic review examining the efficacy of antibiotics in acute respiratory illness concluded that antibiotics are of little benefit. However, that review was based on analysis of only six randomized controlled trials, one of which was excluded because its analysis included patients with multiple episodes of illness; treatment group, either antibiotic or placebo, might have confounded the likelihood of suffering a subsequent episode of illness.. This previously excluded randomized controlled trial of 301 patients with symptoms of minor respiratory illness was re-analysed to examine the efficacy of antibiotic versus placebo in terms of resolution of symptoms, most particularly cough.. Antibiotic had no impact on the resolution of symptoms of cough at 1 and 2 weeks, respectively; adjusted odds ratio 1.2 [95% confidence interval (CI) 0.7--2.1] and 0.8 (95% CI 0.4--1.6). In those 220 (73%) individuals who suffered a cough, 48 (44%) and 19 (17%) of patients taking placebo were still coughing after 1 and 2 weeks, respectively.. It appears that an antibiotic is likely to have, at best, a marginal impact on resolution of symptoms for most patients with minor respiratory illness in the community. Topics: Adult; Anti-Bacterial Agents; Confounding Factors, Epidemiologic; Cough; Demeclocycline; Humans; Male; Middle Aged; Respiratory Tract Infections; Rhinitis; Smoking; Sputum; Suppuration; Time Factors; Treatment Outcome | 2001 |
Other Studies
2 other study(ies) available for demeclocycline and Rhinitis
Article | Year |
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Histology and histomorphometry of ethmoid bone in chronic rhinosinusitis.
Mucosal changes have been well described in chronic sinusitis, yet little is known about the underlying bone, despite clinical and experimental evidence suggesting that bone may be involved in chronic sinusitis. Techniques of undecalcified bone analysis were used for detailed histologic examination of ethmoid bone in chronic sinusitis compared with controls. Bone synthesis, resorption, and inflammatory cell presence were specifically assessed. Additionally, histomorphometry techniques were used to determine ethmoid bone physiology in individuals undergoing surgery for chronic sinusitis. Overall, individuals undergoing surgery for chronic sinusitis were found to have evidence of marked acceleration in bone physiology with histologic changes including new bone formation, fibrosis, and presence of inflammatory cells. These findings are compared with osteomyelitis in long bone and the jaw. The suggestion that underlying bone may serve as a catalyst for chronic sinusitis is supported and implications for therapy are discussed. Topics: Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bone Remodeling; Bone Resorption; Chronic Disease; Coloring Agents; Demeclocycline; Edema; Endoscopy; Ethmoid Bone; Ethmoid Sinusitis; Female; Fibrosis; Humans; Male; Mandibular Diseases; Mucous Membrane; Osteitis; Osteogenesis; Osteomyelitis; Prospective Studies; Rhinitis; Single-Blind Method; Tetracycline; Turbinates | 1998 |
Demethylchlortetracycline used in bacterial infections of ear, nose, and throat.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Demeclocycline; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Otitis; Pharyngitis; Respiratory Tract Infections; Rhinitis | 1970 |