demeclocycline and Osteochondritis-Dissecans

A review of the literature in osteochondritis dissecans of the femoral condyles reveals that the aetiopathology is still unclear and that relatively few histopathological studies have been carried out. The authors describe a method of study based on microradiography and on preoperative fluorescent labelling of the osteogenetic area followed by examination of the bone remodelling under ultraviolet light microscopy. The results in 12 adult cases are reported in relation to a topographical scheme which divides the lesions into four separate zones.

Topics: Adult; Demeclocycline; Female; Femur; Humans; Knee Joint; Male; Microradiography; Microscopy, Fluorescence; Microscopy, Ultraviolet; Middle Aged; Osteochondritis; Osteochondritis Dissecans