deltorphin ii, ala(2)- has been researched along with Ache in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (34.62) | 18.2507 |
| 2000's | 11 (42.31) | 29.6817 |
| 2010's | 6 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fairbanks, CA; Kitto, KF; Messing, RO; Metcalf, MD; Schuster, DJ; Wilcox, GL | 1 |
| Finkelstein, N; Katlowitz, YE; Majumdar, S; Marrone, GF; Pasternak, GW; Pescatore, R; Sedberry, S; Vinton, D; Wilson, KR | 1 |
| Beaudry, H; Chavkin, C; Dory, Y; Gendron, L; Li, S; Proteau-Gagné, A | 1 |
| Ansonoff, MA; Pintar, JE; Portoghese, PS | 1 |
| Dubois, D; Gendron, L | 1 |
| Gendron, L; Otis, V; Sarret, P | 1 |
| Beaudry, H; Dubois, D; Gendron, L | 1 |
| Leitermann, R; Mizoguchi, H; Nagase, H; Spaulding, A; Tseng, LF; Wu, HE | 1 |
| Aono, Y; Cools, AR; Fusa, K; Ikeda, H; Koshikawa, N; Nagase, H; Saigusa, T; Suzuki, T; Takahashi, I; Watanabe, S | 1 |
| Clarke, PB; Pradhan, AA | 1 |
| Borys, D; Hosohata, K; Navratilova, E; Nylen, A; Porreca, F; Roeske, WR; Vanderah, TW; Varga, EV; Yamamura, HI | 1 |
| Hall, FS; Schwasinger, E; Sora, I; Sun, HS; Terashivili, M; Tseng, LF; Uhl, GR; Wu, HE | 1 |
| Hammond, DL; Hurley, RW; Mizoguchi, H; Sykes, KT; Tseng, LF; White, SR | 1 |
| Castro, MA; Garzón, J; Juarros, JL; Sánchez-Blázquez, P | 1 |
| Inturrisi, CE; Jenab, S; Kest, B | 1 |
| Burks, TF; Hruby, VJ; Roerig, SC; Rosenfeld, GC; Williams, CL | 1 |
| Balboni, G; Bryant, SD; Capasso, A; Guerrini, R; Lazarus, LH; Salvadori, S; Sorrentino, L; Temussi, P | 1 |
| Inturrisi, CE; Jenab, S; Kest, B; Lee, CE | 1 |
| DeAntonio, I; DeFelipe, J; García-España, A; Garzón, J; Rodríguez, JR; Sánchez-Blázquez, P | 1 |
| Bian, D; Hruby, VJ; Kovelowski, CJ; Lai, J; Ossipov, MH; Porreca, F | 1 |
| Hruby, VJ; Kovelowski, CJ; Ossipov, MH; Porreca, F | 1 |
| Fairbanks, CA; Kitto, KF; Posthumus, IJ; Stone, LS; Wilcox, GL | 1 |
| Beslot, F; Ledent, C; Parmentier, M; Roques, BP; Valverde, O | 1 |
| Kamei, J; Mizoguchi, H; Nagase, H; Ohsawa, M; Pieper, GM; Tseng, LF | 1 |
| Aoki, T; Mizoguchi, H; Narita, M; Ohsawa, M; Suzuki, T; Tseng, LF | 1 |
| Burks, TF; Carr, DB; Davis, P; Fang, L; Hruby, VJ; Knapp, RJ; Kramer, T; Lipkowski, AW; Misicka, A; Yamamura, HI | 1 |
26 other study(ies) available for deltorphin ii, ala(2)- and Ache
| Article | Year |
|---|---|
Ligand requirements for involvement of PKCε in synergistic analgesic interactions between spinal μ and δ opioid receptors.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Drug Therapy, Combination; Female; Hot Temperature; Ligands; Male; Mice, Knockout; Morphine; Morpholines; Oligopeptides; Pain; Protein Kinase C-epsilon; Protein Multimerization; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord | 2015 |
Synthesis and pharmacology of halogenated δ-opioid-selective [d-Ala(2)]deltorphin II peptide analogues.
Topics: Analgesics, Opioid; Animals; CHO Cells; Chromatography, High Pressure Liquid; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Halogenation; Male; Mice; Oligopeptides; Pain; Peptides; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2015 |
Differential noxious and motor tolerance of chronic delta opioid receptor agonists in rodents.
Topics: Administration, Cutaneous; Animals; Arthritis, Experimental; Dose-Response Relationship, Drug; Drug Tolerance; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Derivatives; Motor Activity; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta | 2009 |
Consequences of opioid receptor mutation on actions of univalent and bivalent kappa and delta ligands.
Topics: Amides; Animals; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Guanidines; Ligands; Male; Mice; Mice, Knockout; Naltrexone; Oligopeptides; Pain; Protein Multimerization; Receptors, Opioid, delta; Receptors, Opioid, kappa | 2010 |
Delta opioid receptor-mediated analgesia is not altered in preprotachykinin A knockout mice.
Topics: Analgesia; Animals; Behavior, Animal; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Neurons; Oligopeptides; Pain; Pain Measurement; Protein Precursors; Receptors, Opioid, delta; Substance P; Tachykinins | 2010 |
Spinal activation of delta opioid receptors alleviates cancer-related bone pain.
Topics: Analgesics, Opioid; Animals; Bone Neoplasms; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Hyperalgesia; Inflammation; Injections, Spinal; Male; Oligopeptides; Pain; Pain Management; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Time Factors | 2011 |
Activation of spinal mu- and delta-opioid receptors potently inhibits substance P release induced by peripheral noxious stimuli.
Topics: Animals; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Formaldehyde; Injections, Spinal; Male; Mice; Mice, Knockout; Neurons; Neurons, Afferent; Oligopeptides; Pain; Pain Measurement; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord; Substance P; Tachykinins | 2011 |
Buprenorphine blocks epsilon- and micro-opioid receptor-mediated antinociception in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; beta-Endorphin; Buprenorphine; Disease Models, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Time Factors | 2003 |
The non-peptidic delta opioid receptor agonist TAN-67 enhances dopamine efflux in the nucleus accumbens of freely moving rats via a mechanism that involves both glutamate and free radicals.
Topics: Adrenergic Uptake Inhibitors; alpha-Methyltyrosine; Animals; Dopamine; Enkephalin, D-Penicillamine (2,5)-; Enzyme Inhibitors; Extracellular Space; Free Radicals; Glutamic Acid; Male; Microdialysis; Naloxone; Narcotic Antagonists; Nucleus Accumbens; Oligopeptides; Pain; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Reserpine | 2005 |
Comparison between delta-opioid receptor functional response and autoradiographic labeling in rat brain and spinal cord.
Topics: Analgesia; Animals; Autoradiography; Brain; Male; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Spinal Cord; Tissue Distribution | 2005 |
Antinociception depends on the presence of G protein gamma2-subunits in brain.
Topics: Analgesics; Analgesics, Opioid; Animals; Benzoxazines; Brain; Clonidine; GTP-Binding Proteins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Morpholines; Naphthalenes; Oligonucleotides, Antisense; Oligopeptides; Pain; Pain Measurement; Time Factors | 2005 |
dextro- and levo-morphine attenuate opioid delta and kappa receptor agonist produced analgesia in mu-opioid receptor knockout mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Opioid; Animals; Female; Genotype; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Nociceptors; Oligopeptides; Pain; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stereoisomerism | 2006 |
Mechanisms responsible for the enhanced antinociceptive effects of micro-opioid receptor agonists in the rostral ventromedial medulla of male rats with persistent inflammatory pain.
Topics: Analgesics; Animals; Cell Membrane; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Freund's Adjuvant; Guanosine 5'-O-(3-Thiotriphosphate); Hindlimb; Hyperalgesia; Inflammation; Male; Medulla Oblongata; Oligopeptides; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, mu | 2007 |
Antibodies raised against the N-terminal sequence of delta opioid receptors blocked delta-mediated supraspinal antinociception in mice.
Topics: Amino Acid Sequence; Analysis of Variance; Animals; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; GTP-Binding Proteins; Immunoglobulin G; Immunohistochemistry; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Morphine; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Protein Binding; Reaction Time; Receptors, Opioid, delta | 1994 |
Assessment of delta opioid antinociception and receptor mRNA levels in mouse after chronic naltrexone treatment.
Topics: Animals; Blotting, Northern; Evaluation Studies as Topic; Male; Mice; Naltrexone; Oligopeptides; Pain; Pain Measurement; Receptors, Opioid, delta; RNA, Messenger; Time Factors | 1995 |
Inhibition of adenylyl cyclase activity by the cholecystokinin analog SNF 9007 in neuroblastoma x glioma NG108-15 hybrid cells.
Topics: Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Analgesics; Cholecystokinin; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Enzyme Inhibitors; Glioma; Hybrid Cells; Molecular Sequence Data; Neuroblastoma; Oligopeptides; Pain; Peptide Fragments; Receptors, Opioid, delta | 1996 |
Dmt-Tic-OH a highly selective and potent delta-opioid dipeptide receptor antagonist after systemic administration in the mouse.
Topics: Animals; Cerebral Ventricles; Dipeptides; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Injections, Subcutaneous; Isoquinolines; Male; Mice; Narcotic Antagonists; Oligopeptides; Pain; Receptors, Opioid, delta; Regression Analysis; Tetrahydroisoquinolines; Time Factors; Tyrosine | 1996 |
Effect of supraspinal antisense oligodeoxynucleotide treatment on delta-opioid receptor mRNA levels in mice.
Topics: Animals; Base Sequence; Brain; Cerebral Ventricles; Frontal Lobe; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Oligonucleotides, Antisense; Oligopeptides; Organ Specificity; Pain; Periaqueductal Gray; Receptors, Opioid, delta; RNA, Messenger; Spinal Cord; Thalamus; Transcription, Genetic | 1997 |
Transport of CSF antibodies to Galpha subunits across neural membranes requires binding to the target protein and protein kinase C activity.
Topics: Analgesics; Analgesics, Opioid; Animals; Autoantibodies; Biological Transport; Brain Chemistry; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Epitopes; GTP-Binding Protein alpha Subunits, Gi-Go; Immunoblotting; Immunoglobulin G; Injections, Intraventricular; Iodine Radioisotopes; Male; Mice; Mice, Inbred Strains; Microscopy, Immunoelectron; Morphine; Neurons; Nociceptors; Oligopeptides; Pain; Protein Kinase C; Signal Transduction | 1999 |
Selective opioid delta agonists elicit antinociceptive supraspinal/spinal synergy in the rat.
Topics: Analgesics; Animals; Drug Synergism; Enkephalin, D-Penicillamine (2,5)-; Hot Temperature; Injections, Spinal; Male; Medulla Oblongata; Microinjections; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Spinal Cord | 1999 |
Lesions of the dorsolateral funiculus block supraspinal opioid delta receptor mediated antinociception in the rat.
Topics: Animals; Brain Mapping; Cerebral Ventricles; Formaldehyde; Injections, Intraventricular; Male; Medulla Oblongata; Microinjections; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Reticular Formation; Spinal Cord; Time Factors | 1999 |
Moxonidine, a selective imidazoline/alpha(2) adrenergic receptor agonist, synergizes with morphine and deltorphin II to inhibit substance P-induced behavior in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Aggression; Animals; Antihypertensive Agents; Drug Synergism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Imidazoles; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Oligopeptides; Pain; Spinal Cord; Substance P | 2000 |
Reduction of stress-induced analgesia but not of exogenous opioid effects in mice lacking CB1 receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Dopamine; Electroshock; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Exploratory Behavior; Foot; Habituation, Psychophysiologic; Hot Temperature; Mice; Mice, Knockout; Models, Neurological; Morphine; Motor Activity; Nociceptors; Oligopeptides; Pain; Pain Threshold; Receptors, Cannabinoid; Receptors, Drug; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stress, Mechanical; Stress, Physiological; Swimming; Tail; Viscera | 2000 |
Decreased opioid-induced antinociception but unaltered G-protein activation in the genetic-diabetic NOD mouse.
Topics: Analgesics, Opioid; Animals; Benzamides; Binding, Competitive; Diabetes Mellitus, Type 1; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Injections, Intraventricular; Medulla Oblongata; Membranes; Mice; Mice, Inbred NOD; Nociceptors; Oligopeptides; Pain; Piperazines; Pons; Receptors, Opioid; Sulfur Radioisotopes | 2000 |
Role of the phosphatidylinositol-specific phospholipase C pathway in delta-opioid receptor-mediated antinociception in the mouse spinal cord.
Topics: Analgesics; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Estrenes; Indoles; Inositol 1,4,5-Trisphosphate; Male; Mice; Mice, Inbred ICR; Naphthalenes; Oligopeptides; Pain; Pain Measurement; Phosphatidylinositols; Protein Kinase C; Pyrroles; Pyrrolidinones; Receptors, Opioid, delta; Signal Transduction; Spinal Cord; Type C Phospholipases | 2000 |
Topographical requirements for delta opioid ligands: presence of a carboxyl group in position 4 is not critical for deltorphin high delta receptor affinity and analgesic activity.
Topics: Amino Acid Sequence; Analgesics; Animals; Binding, Competitive; Brain; Male; Models, Molecular; Molecular Sequence Data; Oligopeptides; Pain; Protein Conformation; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta | 1991 |