delavirdine has been researched along with Pregnancy in 7 studies
Delavirdine: A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.
delavirdine : The amide resulting from the formal condensation of 5-[(methylsulfonyl)amino]-1H-indole-2-carboxylic acid and 4-amino group of 1-[3-(isopropylamino)pyridin-2-yl]piperazine, delavirdine is a non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1. Viral resistance emerges rapidly when delavirdine is used alone, so it is therefore used (as the methanesulfonic acid salt) with other antiretrovirals for combination therapy of HIV infection.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Delavirdine is an effective component of recommended antiretroviral treatment strategies for adult patients with HIV infection and, in combination with 2 NRTIs as a first-line therapy, the drug has the advantage of sparing protease inhibitors for subsequent use." | 2.41 | Delavirdine: a review of its use in HIV infection. ( Perry, CM; Scott, LJ, 2000) |
| " Although possessing a common mechanism of action, these agents can be differentiated by both molecular and pharmacokinetic characteristics." | 2.41 | Clinical pharmacokinetics of non-nucleoside reverse transcriptase inhibitors. ( DiCenzo, R; Morse, GD; Smith, PF, 2001) |
| " The bioavailability of soft-gel saquinavir (Fortovase) compared with the hard gel formulation (Invirase) is discussed." | 1.30 | Product information. ( Bartlett, JG, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reid, M | 1 |
| Lorimer, K | 1 |
| Norman, JE | 1 |
| Bollapragada, SS | 1 |
| Norrie, J | 1 |
| Kurle, SN | 1 |
| Gangakhedkar, RR | 1 |
| Sen, S | 1 |
| Hayatnagarkar, SS | 1 |
| Tripathy, SP | 1 |
| Paranjape, RS | 1 |
| Temesgen, Z | 1 |
| Wright, AJ | 1 |
| Scott, LJ | 1 |
| Perry, CM | 1 |
| Bartlett, JG | 1 |
| Smith, PF | 1 |
| DiCenzo, R | 1 |
| Morse, GD | 1 |
3 reviews available for delavirdine and Pregnancy
| Article | Year |
|---|---|
Antiretrovirals.
Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; Cyclopropanes; Delavirdine; D | 1999 |
Delavirdine: a review of its use in HIV infection.
Topics: Anti-HIV Agents; Delavirdine; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibi | 2000 |
Clinical pharmacokinetics of non-nucleoside reverse transcriptase inhibitors.
Topics: Alkynes; Benzoxazines; Biological Availability; Cyclopropanes; Delavirdine; Drug Interactions; Femal | 2001 |
1 trial available for delavirdine and Pregnancy
| Article | Year |
|---|---|
The home as an appropriate setting for women undertaking cervical ripening before the induction of labour.
Topics: Administration, Intravaginal; Adult; Ambulatory Care; Cervical Ripening; Delavirdine; Female; Home C | 2011 |
3 other studies available for delavirdine and Pregnancy
| Article | Year |
|---|---|
Emergence of NNRTI drug resistance mutations after single-dose nevirapine exposure in HIV type 1 subtype C-infected infants in India.
Topics: Alkynes; Benzoxazines; Cyclopropanes; Delavirdine; Drug Resistance, Viral; Feasibility Studies; Fema | 2007 |
New developments in women and AIDS research.
Topics: AIDS-Related Opportunistic Infections; Delavirdine; Drug Therapy, Combination; Estrogens; Female; HI | 1997 |
Product information.
Topics: Anti-Infective Agents; Bacterial Infections; Biological Availability; Capsules; Clinical Trials as T | 1998 |