dehydroepiandrosterone has been researched along with Weight Loss in 17 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Weight Loss: Decrease in existing BODY WEIGHT.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the effect of weight reduction on serum dehydroepiandrosterone (DHEA)-sulfate, insulin, and glucose, these parameters were assessed in 18 men and 29 women before and after weight loss achieved by a 2-month 1000-1400 kcal diet." | 7.69 | Disparate effects of weight reduction by diet on serum dehydroepiandrosterone-sulfate levels in obese men and women. ( Beer, NA; Beer, RM; Jakubowicz, DJ; Nestler, JE, 1995) |
| " Baseline and end line assessment were performed for menstrual cycle regularity, ultrasonography scan for ovaries, total testosterone, dehydroepiandrosterone (DHEAS), insulin, luteinizing hormone/follicle stimulating hormone (LH/FSH) ratio, fasting blood sugar (FBS), homeostatic model assessment-insulin resistance (HOMA-IR), weight reduction, waist-/hip circumference (WC, HC), waist to hip ratio (WHR), and body mass index (BMI)." | 5.51 | Efficacy of multi-strain probiotic along with dietary and lifestyle modifications on polycystic ovary syndrome: a randomised, double-blind placebo-controlled study. ( Ahire, J; Kaur, I; Medhi, B; Rana, SV; Sachdeva, N; Sahni, N; Singh, A; Suri, V, 2022) |
| "In this study, the effects of DHEA treatment on insulin sensitivity were investigated in genetically obese Zucker rats, an animal model of insulin resistance, using the euglycemic clamp technique." | 5.30 | Dehydroepiandrosterone decreases serum tumor necrosis factor-alpha and restores insulin sensitivity: independent effect from secondary weight reduction in genetically obese Zucker fatty rats. ( Kimura, M; Kiuchi, Y; Sekihara, H; Tanaka, S; Yamada, Y; Yamakawa, T, 1998) |
| "Dehydroepiandrosterone (DHEA) has been shown to have antiobesity activity in rodents and spontaneously obese dogs." | 5.08 | The effect of dehydroepiandrosterone combined with a low-fat diet in spontaneously obese dogs: a clinical trial. ( Kurzman, ID; MacEwen, EG; Miller, JB; Panciera, DL, 1998) |
| "To assess the effect of weight reduction on serum dehydroepiandrosterone (DHEA)-sulfate, insulin, and glucose, these parameters were assessed in 18 men and 29 women before and after weight loss achieved by a 2-month 1000-1400 kcal diet." | 3.69 | Disparate effects of weight reduction by diet on serum dehydroepiandrosterone-sulfate levels in obese men and women. ( Beer, NA; Beer, RM; Jakubowicz, DJ; Nestler, JE, 1995) |
| "Frequent weight loss was also associated with lower androgen concentrations, including androstenedione (P trend = ." | 1.36 | Frequent intentional weight loss is associated with higher ghrelin and lower glucose and androgen levels in postmenopausal women. ( Foster-Schubert, KE; Hooper, LE; McTiernan, A; Sorensen, B; Ulrich, CM; Weigle, DS, 2010) |
| "In this study, the effects of DHEA treatment on insulin sensitivity were investigated in genetically obese Zucker rats, an animal model of insulin resistance, using the euglycemic clamp technique." | 1.30 | Dehydroepiandrosterone decreases serum tumor necrosis factor-alpha and restores insulin sensitivity: independent effect from secondary weight reduction in genetically obese Zucker fatty rats. ( Kimura, M; Kiuchi, Y; Sekihara, H; Tanaka, S; Yamada, Y; Yamakawa, T, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (47.06) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Kaur, I | 1 |
| Suri, V | 1 |
| Sachdeva, N | 1 |
| Rana, SV | 1 |
| Medhi, B | 1 |
| Sahni, N | 1 |
| Ahire, J | 1 |
| Singh, A | 1 |
| Ara, J | 1 |
| Nuwormegbe, SA | 1 |
| Sajo, MEJ | 1 |
| Kim, SK | 1 |
| Shim, KY | 1 |
| Lee, KJ | 1 |
| Voznesensky, M | 1 |
| Walsh, S | 1 |
| Dauser, D | 1 |
| Brindisi, J | 1 |
| Kenny, AM | 1 |
| Hooper, LE | 1 |
| Foster-Schubert, KE | 1 |
| Weigle, DS | 1 |
| Sorensen, B | 1 |
| Ulrich, CM | 1 |
| McTiernan, A | 1 |
| Woodard, G | 1 |
| Ahmed, S | 1 |
| Podelski, V | 1 |
| Hernandez-Boussard, T | 1 |
| Presti, J | 1 |
| Morton, JM | 1 |
| Miller, GD | 1 |
| Nicklas, BJ | 1 |
| Davis, CC | 1 |
| Legault, C | 1 |
| Messier, SP | 1 |
| Morley, JE | 1 |
| Kim, MJ | 1 |
| Haren, MT | 1 |
| Pélissier, MA | 1 |
| Muller, C | 1 |
| Hill, M | 1 |
| Morfin, R | 1 |
| Jakubowicz, DJ | 1 |
| Beer, NA | 1 |
| Beer, RM | 1 |
| Nestler, JE | 1 |
| Leenen, R | 1 |
| van der Kooy, K | 1 |
| Seidell, JC | 1 |
| Deurenberg, P | 1 |
| Koppeschaar, HP | 1 |
| Remer, T | 1 |
| Wabitsch, M | 1 |
| Blum, WF | 1 |
| Muche, R | 1 |
| Heinze, E | 1 |
| Haug, C | 1 |
| Mayer, H | 1 |
| Teller, W | 1 |
| Christeff, N | 1 |
| Gherbi, N | 1 |
| Mammes, O | 1 |
| Dalle, MT | 1 |
| Gharakhanian, S | 1 |
| Lortholary, O | 1 |
| Melchior, JC | 1 |
| Nunez, EA | 1 |
| Kurzman, ID | 2 |
| Panciera, DL | 1 |
| Miller, JB | 1 |
| MacEwen, EG | 2 |
| Kimura, M | 1 |
| Tanaka, S | 1 |
| Yamada, Y | 1 |
| Kiuchi, Y | 1 |
| Yamakawa, T | 1 |
| Sekihara, H | 1 |
| Hu, Y | 1 |
| Cardounel, A | 1 |
| Gursoy, E | 1 |
| Anderson, P | 1 |
| Kalimi, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of DHEA on Skin Aging - Placebo-Controlled and Randomized Phase III Study in Postmenopausal Women.[NCT00248989] | Phase 3 | 150 participants (Actual) | Interventional | 2004-11-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for dehydroepiandrosterone and Weight Loss
| Article | Year |
|---|---|
Frailty and hormones.
Topics: Aged; Cachexia; Cytokines; Dehydroepiandrosterone; Diabetes Mellitus; Frail Elderly; Hormones; Human | 2005 |
Obesity in the dog: role of the adrenal steroid dehydroepiandrosterone (DHEA).
Topics: Animals; Cholesterol; Dehydroepiandrosterone; Dog Diseases; Dogs; Obesity; Weight Loss | 1991 |
4 trials available for dehydroepiandrosterone and Weight Loss
| Article | Year |
|---|---|
Efficacy of multi-strain probiotic along with dietary and lifestyle modifications on polycystic ovary syndrome: a randomised, double-blind placebo-controlled study.
Topics: Adolescent; Adult; Blood Glucose; Body Mass Index; Dehydroepiandrosterone; Diet; Female; Follicle St | 2022 |
Basal growth hormone concentration increased following a weight loss focused dietary intervention in older overweight and obese women.
Topics: Aged; Aging; Dehydroepiandrosterone; Female; Human Growth Hormone; Humans; Hydrocortisone; Male; Nut | 2012 |
Serum cortisol and DHEA concentrations during HIV infection.
Topics: Adult; Blotting, Western; Cachexia; CD4-CD8 Ratio; Dehydroepiandrosterone; HIV Infections; HIV Serop | 1997 |
The effect of dehydroepiandrosterone combined with a low-fat diet in spontaneously obese dogs: a clinical trial.
Topics: Animals; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dehydroepiandrosterone; Diet, Fat-Restrict | 1998 |
11 other studies available for dehydroepiandrosterone and Weight Loss
| Article | Year |
|---|---|
Potential therapeutic effect of alkaline reduced water in polycystic ovarian syndrome.
Topics: Animals; Dehydroepiandrosterone; Female; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydr | 2017 |
The association between dehydroepiandosterone and frailty in older men and women.
Topics: Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Dehydroepiandrosterone; Female; Frail Elder | 2009 |
Frequent intentional weight loss is associated with higher ghrelin and lower glucose and androgen levels in postmenopausal women.
Topics: Aged; Androgens; Appetite; Blood Glucose; Body Mass Index; Cross-Sectional Studies; Dehydroepiandros | 2010 |
Effect of Roux-en-Y gastric bypass on testosterone and prostate-specific antigen.
Topics: Body Mass Index; Dehydroepiandrosterone; Delayed Diagnosis; Gastric Bypass; Humans; Male; Middle Age | 2012 |
Protection against dextran sodium sulfate-induced colitis by dehydroepiandrosterone and 7alpha-hydroxy-dehydroepiandrosterone in the rat.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adjuvants, | 2006 |
Disparate effects of weight reduction by diet on serum dehydroepiandrosterone-sulfate levels in obese men and women.
Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diet, Reducing; Female; Humans; Male; | 1995 |
Visceral fat accumulation in relation to sex hormones in obese men and women undergoing weight loss therapy.
Topics: Adipose Tissue; Adult; Androstenedione; Body Composition; Dehydroepiandrosterone; Dehydroepiandroste | 1994 |
Disparate effects of weight reduction by diet on serum dehydroepiandrosterone-sulfate levels in obese men and women.
Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Male; Obesity; Weight Loss | 1996 |
Insulin-like growth factors and their binding proteins before and after weight loss and their associations with hormonal and metabolic parameters in obese adolescent girls.
Topics: Adolescent; Age Factors; Blood Pressure; Body Constitution; Body Mass Index; Cholesterol; Dehydroepi | 1996 |
Dehydroepiandrosterone decreases serum tumor necrosis factor-alpha and restores insulin sensitivity: independent effect from secondary weight reduction in genetically obese Zucker fatty rats.
Topics: Animals; Body Weight; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Eating; Female; Glucos | 1998 |
Anti-stress effects of dehydroepiandrosterone: protection of rats against repeated immobilization stress-induced weight loss, glucocorticoid receptor production, and lipid peroxidation.
Topics: Animals; Dehydroepiandrosterone; Female; Immobilization; Lipid Peroxidation; Male; Rats; Rats, Sprag | 2000 |