dehydroepiandrosterone has been researched along with Weight Gain in 14 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Weight Gain: Increase in BODY WEIGHT over existing weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to investigate for the first time efficacy of DHEA augmentation with standardized antipsychotic medication (olanzapine) and to explore effects of DHEA augmentation on side-effect profiles including weight gain, glucose tolerance, aggression, quality of life and neurocognitive function." | 9.12 | Analysis of clinical symptomatology, extrapyramidal symptoms and neurocognitive dysfunction following dehydroepiandrosterone (DHEA) administration in olanzapine treated schizophrenia patients: a randomized, double-blind placebo controlled trial. ( Eisner, D; Gal, G; Katz, E; Maayan, R; Strous, RD; Stryjer, R; Viglin, D; Weizman, A, 2007) |
| " This study aimed to assess the ability of EM-652, alone or with dehydroepiandrosterone (DHEA), to prevent obesity and related metabolic abnormalities induced by an obesity-promoting diet and ovariectomy." | 7.72 | The estrogen antagonist EM-652 and dehydroepiandrosterone prevent diet- and ovariectomy-induced obesity. ( Deshaies, Y; Labrie, F; Lemieux, C; Picard, F; Richard, D, 2003) |
| " The fatty liver induced by orotic acid and a high sucrose diet in male rats was prevented by the administration of DHEA and/or phenobarbital (PB)." | 7.70 | Prevention of orotic-acid-induced fatty liver in male rats by dehydroepiandrosterone and/or phenobarbital. ( Goto, H; Makita, T; Yamashita, S, 1998) |
| "Although antiobesity effect of dehydroepiandrosterone (DHEA) has been reported in rats, it remains unclear whether the effect is brought about by itself or mediated by sex steroids converted from DHEA in gonads." | 7.69 | The antiobesity effect of dehydroepiandrosterone in castrated or noncastrated obese Zucker male rats. ( Haji, M; Ishibashi, K; Nawata, H; Takayanagi, R; Taniguchi, S; Yanase, T, 1995) |
| "Treatment outcome in congenital adrenal hyperplasia is often suboptimal due to hyperandrogenism, treatment-induced hypercortisolism, or both." | 6.68 | A preliminary study of flutamide, testolactone, and reduced hydrocortisone dose in the treatment of congenital adrenal hyperplasia. ( Barnes, KM; Cutler, GB; Hill, S; Jones, JV; Laue, L; Merke, DP, 1996) |
| " The aim of this study was to investigate for the first time efficacy of DHEA augmentation with standardized antipsychotic medication (olanzapine) and to explore effects of DHEA augmentation on side-effect profiles including weight gain, glucose tolerance, aggression, quality of life and neurocognitive function." | 5.12 | Analysis of clinical symptomatology, extrapyramidal symptoms and neurocognitive dysfunction following dehydroepiandrosterone (DHEA) administration in olanzapine treated schizophrenia patients: a randomized, double-blind placebo controlled trial. ( Eisner, D; Gal, G; Katz, E; Maayan, R; Strous, RD; Stryjer, R; Viglin, D; Weizman, A, 2007) |
| "Nineteen female adolescent inpatients diagnosed with anorexia nervosa, restricting type (AN-R) and 16 non-eating disordered (ED) controls were assessed for plasma dehydroepiandrosterone (DHEA), dehydroepiandrosterone-sulphate (DHEA-S), and cortisol levels, and for eating-related and non-eating-related psychopathology." | 3.73 | Circulatory neurosteroid levels in underweight female adolescent anorexia nervosa inpatients and following weight restoration. ( Achiron, A; Feigin, M; Loewenthal, R; Maayan, R; Modan-Moses, D; Ram, A; Stein, D; Valevski, A; Weizman, A, 2005) |
| " This study aimed to assess the ability of EM-652, alone or with dehydroepiandrosterone (DHEA), to prevent obesity and related metabolic abnormalities induced by an obesity-promoting diet and ovariectomy." | 3.72 | The estrogen antagonist EM-652 and dehydroepiandrosterone prevent diet- and ovariectomy-induced obesity. ( Deshaies, Y; Labrie, F; Lemieux, C; Picard, F; Richard, D, 2003) |
| " The fatty liver induced by orotic acid and a high sucrose diet in male rats was prevented by the administration of DHEA and/or phenobarbital (PB)." | 3.70 | Prevention of orotic-acid-induced fatty liver in male rats by dehydroepiandrosterone and/or phenobarbital. ( Goto, H; Makita, T; Yamashita, S, 1998) |
| " When administered to obese, hypercorticosteronemic Zucker rats, it causes a diminution of food intake and a reduction in their rate of weight gain." | 3.69 | The effect of DHEA given chronically to Zucker rats. ( Browne, E; Hilton, CW; Porter, JR; Svec, F; Wright, B, 1995) |
| "Although antiobesity effect of dehydroepiandrosterone (DHEA) has been reported in rats, it remains unclear whether the effect is brought about by itself or mediated by sex steroids converted from DHEA in gonads." | 3.69 | The antiobesity effect of dehydroepiandrosterone in castrated or noncastrated obese Zucker male rats. ( Haji, M; Ishibashi, K; Nawata, H; Takayanagi, R; Taniguchi, S; Yanase, T, 1995) |
| "Treatment outcome in congenital adrenal hyperplasia is often suboptimal due to hyperandrogenism, treatment-induced hypercortisolism, or both." | 2.68 | A preliminary study of flutamide, testolactone, and reduced hydrocortisone dose in the treatment of congenital adrenal hyperplasia. ( Barnes, KM; Cutler, GB; Hill, S; Jones, JV; Laue, L; Merke, DP, 1996) |
| "Dehydroepiandrosterone (DHEA) is an adrenal steroid hormone that is a precursor of sexual hormones." | 1.48 | Dehydroepiandrosterone supplementation is not beneficial in the late postmenopausal period in diet-induced obese rats. ( Curi, R; da Cunha Araujo, LC; de Oliveira Carvalho, CR; Ribeiro, LM; Teixeira, CJ; Veras, K, 2018) |
| "The data about smoking cessation are limited; there has not yet been a study primarily focused on changes in steroids levels." | 1.39 | Effects of smoking cessation on hormonal levels in men. ( Dušková, M; Hill, M; Hruškovičová, H; Králíková, E; Pospíšilová, H; Rácz, B; Simůnková, K; Stárka, L; Vondra, K, 2013) |
| "Frequent weight loss was also associated with lower androgen concentrations, including androstenedione (P trend = ." | 1.36 | Frequent intentional weight loss is associated with higher ghrelin and lower glucose and androgen levels in postmenopausal women. ( Foster-Schubert, KE; Hooper, LE; McTiernan, A; Sorensen, B; Ulrich, CM; Weigle, DS, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Teixeira, CJ | 1 |
| Ribeiro, LM | 1 |
| Veras, K | 1 |
| da Cunha Araujo, LC | 1 |
| Curi, R | 1 |
| de Oliveira Carvalho, CR | 1 |
| Tessaro, I | 1 |
| Modina, SC | 1 |
| Franciosi, F | 1 |
| Sivelli, G | 1 |
| Terzaghi, L | 1 |
| Lodde, V | 1 |
| Luciano, AM | 1 |
| Hooper, LE | 1 |
| Foster-Schubert, KE | 1 |
| Weigle, DS | 1 |
| Sorensen, B | 1 |
| Ulrich, CM | 1 |
| McTiernan, A | 1 |
| Hruškovičová, H | 1 |
| Dušková, M | 1 |
| Simůnková, K | 1 |
| Hill, M | 1 |
| Pospíšilová, H | 1 |
| Rácz, B | 1 |
| Králíková, E | 1 |
| Vondra, K | 1 |
| Stárka, L | 1 |
| Lemieux, C | 1 |
| Picard, F | 1 |
| Labrie, F | 1 |
| Richard, D | 1 |
| Deshaies, Y | 1 |
| UJSAGHY, P | 1 |
| Stein, D | 1 |
| Maayan, R | 2 |
| Ram, A | 1 |
| Loewenthal, R | 1 |
| Achiron, A | 1 |
| Modan-Moses, D | 1 |
| Feigin, M | 1 |
| Weizman, A | 2 |
| Valevski, A | 1 |
| Strous, RD | 1 |
| Stryjer, R | 1 |
| Gal, G | 1 |
| Viglin, D | 1 |
| Katz, E | 1 |
| Eisner, D | 1 |
| Jayasinghe, Y | 1 |
| Grover, SR | 1 |
| Zacharin, M | 1 |
| Svec, F | 2 |
| Hilton, CW | 1 |
| Wright, B | 1 |
| Browne, E | 1 |
| Porter, JR | 2 |
| Wright, BE | 1 |
| Browne, ES | 1 |
| Taniguchi, S | 1 |
| Yanase, T | 1 |
| Haji, M | 1 |
| Ishibashi, K | 1 |
| Takayanagi, R | 1 |
| Nawata, H | 1 |
| Laue, L | 1 |
| Merke, DP | 1 |
| Jones, JV | 1 |
| Barnes, KM | 1 |
| Hill, S | 1 |
| Cutler, GB | 1 |
| Goto, H | 1 |
| Yamashita, S | 1 |
| Makita, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Novel Therapeutic Modality for Congenital Adrenal Hyperplasia[NCT00529841] | 7 participants (Actual) | Interventional | 2007-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for dehydroepiandrosterone and Weight Gain
| Article | Year |
|---|---|
Current concepts in bone and reproductive health in adolescents with anorexia nervosa.
Topics: Adolescent; Anorexia Nervosa; Bone Density; Bone Density Conservation Agents; Bone Diseases; Bone Re | 2008 |
2 trials available for dehydroepiandrosterone and Weight Gain
| Article | Year |
|---|---|
Analysis of clinical symptomatology, extrapyramidal symptoms and neurocognitive dysfunction following dehydroepiandrosterone (DHEA) administration in olanzapine treated schizophrenia patients: a randomized, double-blind placebo controlled trial.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Cognition; Dehydroepi | 2007 |
A preliminary study of flutamide, testolactone, and reduced hydrocortisone dose in the treatment of congenital adrenal hyperplasia.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Bone Dev | 1996 |
11 other studies available for dehydroepiandrosterone and Weight Gain
| Article | Year |
|---|---|
Dehydroepiandrosterone supplementation is not beneficial in the late postmenopausal period in diet-induced obese rats.
Topics: Adiposity; Animals; Dehydroepiandrosterone; Diet, High-Fat; Dietary Supplements; Eating; Female; Glu | 2018 |
Effect of oral administration of low-dose follicle stimulating hormone on hyperandrogenized mice as a model of polycystic ovary syndrome.
Topics: Adjuvants, Immunologic; Administration, Oral; Analysis of Variance; Animals; Aromatase; Dehydroepian | 2015 |
Frequent intentional weight loss is associated with higher ghrelin and lower glucose and androgen levels in postmenopausal women.
Topics: Aged; Androgens; Appetite; Blood Glucose; Body Mass Index; Cross-Sectional Studies; Dehydroepiandros | 2010 |
Effects of smoking cessation on hormonal levels in men.
Topics: Administration, Cutaneous; Adult; Analysis of Variance; Biomarkers; Body Mass Index; Dehydroepiandro | 2013 |
The estrogen antagonist EM-652 and dehydroepiandrosterone prevent diet- and ovariectomy-induced obesity.
Topics: Adipose Tissue; Animals; Body Composition; Body Weight; Cholesterol; Dehydroepiandrosterone; Diet; D | 2003 |
[Effect of nor-androstenolone phenylpropionate (Durabolin) on weight increase in atrophic children].
Topics: Body Weight; Child; Dehydroepiandrosterone; Humans; Infant; Infant Nutrition Disorders; Nandrolone; | 1962 |
Circulatory neurosteroid levels in underweight female adolescent anorexia nervosa inpatients and following weight restoration.
Topics: Adolescent; Adult; Anorexia Nervosa; Body Mass Index; Dehydroepiandrosterone; Dehydroepiandrosterone | 2005 |
The effect of DHEA given chronically to Zucker rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Blood Glucose; Corticosterone; Dehydroepiandro | 1995 |
Divergent effect of dehydroepiandrosterone on energy intakes of Zucker rats.
Topics: Animals; Appetite; Dehydroepiandrosterone; Energy Intake; Energy Metabolism; Feeding Behavior; Femal | 1993 |
The antiobesity effect of dehydroepiandrosterone in castrated or noncastrated obese Zucker male rats.
Topics: Animals; Dehydroepiandrosterone; Kinetics; Male; Obesity; Orchiectomy; Rats; Rats, Zucker; Weight Ga | 1995 |
Prevention of orotic-acid-induced fatty liver in male rats by dehydroepiandrosterone and/or phenobarbital.
Topics: Analysis of Variance; Animals; Cells, Cultured; Dehydroepiandrosterone; Dietary Sucrose; Energy Inta | 1998 |