dehydroepiandrosterone has been researched along with Turner Syndrome in 24 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Turner Syndrome: A syndrome of defective gonadal development in phenotypic females associated with the karyotype 45,X (or 45,XO). Patients generally are of short stature with undifferentiated GONADS (streak gonads), SEXUAL INFANTILISM, HYPOGONADISM, webbing of the neck, cubitus valgus, elevated GONADOTROPINS, decreased ESTRADIOL level in blood, and CONGENITAL HEART DEFECTS. NOONAN SYNDROME (also called Pseudo-Turner Syndrome and Male Turner Syndrome) resembles this disorder; however, it occurs in males and females with a normal karyotype and is inherited as an autosomal dominant.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In girls with Turner's syndrome a positive effect of growth hormone (GH) therapy on statutal growth has been well documented, in spite of the fact that the levels of GH and IGF-I in these patients are usually within the normal range." | 1.31 | Sex hormone-binding globulin as a marker of the effect of hormonal treatment in Turner's syndrome. ( Dvorakova, M; Hampl, R; Hill, M; Lebl, J; Lisa, L; Snajderova, M; Starka, L; Sulcova, J, 2001) |
| "The GH axis was studied in Turner's syndrome (TS) patients." | 1.28 | Assessment of growth hormone (GH) axis in Turner's syndrome using 24-hour integrated concentrations of GH, insulin-like growth factor-I, plasma GH-binding activity, GH binding to IM9 cells, and GH response to pharmacological stimulation. ( Altman, Y; Chen, M; Landau, H; Lieberman, E; Zadik, Z, 1992) |
| "60 patients (139 blood specimens) with Turner's syndrome were investigated in order to obtain information concerning the origin of the increments of androgens during puberty." | 1.26 | Subnormal pubertal increases of serum androgens in Turner's syndrome. ( Apter, D; Lenko, HL; Perheentupa, J; Söderholm, A; Vihko, R, 1982) |
| "Children with Turner's syndrome and hypergonadotrophic males had the response in elevated DHA levels while ACTH-induced DHA response related to bone-age matched controls." | 1.26 | Responsiveness of cortisol and dehydroepiandrosterone to ACTH in children. ( Gupta, D; Ranke, MB; Rosendahl, W, 1982) |
| "To evaluate the relationship between the secretion of gonadotropins and adrenal androgens, patients with gonadal agenesis were evaluated by (a) administering human luteinizing hormone (hLH) for 5 days with or without estrogen pretreatment to agonadal patients who had prepubertal LH levels; (b) correlating circulating gonadotropin levels with adrenal androgens in 45 patients; and (c) comparing adrenal androgens with gonadotropins after long-term administration of estrogen or androgens." | 1.25 | Lack of correlation between gonadotropin and adrenal androgen levels in agonadal children. ( Blizzard, RM; Kowarski, A; Lee, PA; Migeon, CJ, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (79.17) | 18.7374 |
| 1990's | 2 (8.33) | 18.2507 |
| 2000's | 2 (8.33) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johannsen, TH | 1 |
| Main, KM | 1 |
| Ljubicic, ML | 1 |
| Jensen, TK | 1 |
| Andersen, HR | 1 |
| Andersen, MS | 1 |
| Petersen, JH | 1 |
| Andersson, AM | 1 |
| Juul, A | 1 |
| Mason, A | 1 |
| Wallace, AM | 1 |
| Macintyre, H | 1 |
| Teoh, YP | 1 |
| Bath, LE | 1 |
| Critchley, HO | 1 |
| Kelnar, CJ | 1 |
| Wallace, WH | 1 |
| Ahmed, SF | 1 |
| Schönberger, W | 1 |
| Benes, P | 1 |
| Morsches, B | 1 |
| Zabel, B | 1 |
| Scheidt, E | 1 |
| Apter, D | 1 |
| Lenko, HL | 1 |
| Perheentupa, J | 1 |
| Söderholm, A | 1 |
| Vihko, R | 1 |
| Ranke, MB | 1 |
| Rosendahl, W | 1 |
| Gupta, D | 3 |
| Reiter, EO | 1 |
| Duckett, GE | 1 |
| Root, AW | 1 |
| Balducci, R | 1 |
| Toscano, V | 1 |
| Larizza, D | 1 |
| Mangiantini, A | 1 |
| Galasso, C | 1 |
| Municchi, G | 1 |
| Di Rito, A | 1 |
| Picone, S | 1 |
| Boscherini, B | 1 |
| Hampl, R | 1 |
| Snajderova, M | 1 |
| Lebl, J | 1 |
| Lisa, L | 1 |
| Dvorakova, M | 1 |
| Hill, M | 1 |
| Sulcova, J | 1 |
| Starka, L | 1 |
| McDonough, PG | 1 |
| Ellegood, JO | 1 |
| Byrd, JR | 1 |
| Mahesh, VB | 1 |
| Drucker, WD | 1 |
| Lee, PA | 1 |
| Kowarski, A | 1 |
| Migeon, CJ | 1 |
| Blizzard, RM | 1 |
| Boyar, RM | 1 |
| Lucky, AW | 1 |
| Marynick, SP | 1 |
| Rebar, RW | 1 |
| Cutler, GB | 1 |
| Glen, M | 1 |
| Johnsonbaugh, RE | 1 |
| Loriaux, DL | 1 |
| Zadik, Z | 1 |
| Landau, H | 1 |
| Chen, M | 1 |
| Altman, Y | 1 |
| Lieberman, E | 1 |
| Teller, WM | 1 |
| Homoki, J | 1 |
| Wudy, S | 1 |
| Schlickenrieder, JH | 1 |
| Rivera, R | 1 |
| Dorfman, RI | 1 |
| Forchielli, E | 1 |
| Zimprich, H | 3 |
| Bardin, CW | 1 |
| Rosen, S | 1 |
| LeMaire, WJ | 1 |
| Tjio, JH | 1 |
| Gallup, J | 1 |
| Marshall, J | 1 |
| Savard, K | 1 |
| Pujol-Amat, P | 1 |
| Esteban-Altirriba, J | 1 |
| Venrell-Diaz, J | 1 |
| Tejero, A | 1 |
| Oriol-Bosch, A | 1 |
| Ribas-Mundo, J | 1 |
| Prats-Viñas, J | 1 |
| Wieland, RG | 1 |
| Ekstrom, B | 1 |
| Vorys, N | 1 |
| Ríos, EP | 1 |
| Herrera, J | 1 |
| Bermúdez, JA | 1 |
| Rocha, G | 1 |
| Lisker, R | 1 |
| Morato, T | 1 |
| Pérez-Palacios, G | 1 |
| Mackay, AM | 1 |
| Pettigrew, N | 1 |
| Symington, T | 1 |
| Neville, AM | 1 |
| Pfeiffer, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Turner Syndrome Minipuberty Study A Prospective, Descriptive Cohortstudy[NCT04189406] | 30 participants (Anticipated) | Observational | 2020-02-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for dehydroepiandrosterone and Turner Syndrome
| Article | Year |
|---|---|
Biologic activity and metabolism of androgenic hormones: the role of the adrenal androgens.
Topics: Adrenal Glands; Androgens; Dehydroepiandrosterone; Dihydrotestosterone; Female; Hair; Humans; Male; | 1977 |
Control of the onset of puberty.
Topics: Adolescent; Adrenocorticotropic Hormone; Androstenedione; Anorexia Nervosa; Dehydroepiandrosterone; | 1978 |
22 other studies available for dehydroepiandrosterone and Turner Syndrome
| Article | Year |
|---|---|
Sex Differences in Reproductive Hormones During Mini-Puberty in Infants With Normal and Disordered Sex Development.
Topics: Androstenedione; Anti-Mullerian Hormone; Cross-Sectional Studies; Dehydroepiandrosterone; Dehydroepi | 2018 |
Undetectable salivary testosterone in young women with premature ovarian failure.
Topics: Adult; Androstenedione; Biomarkers; Cross-Sectional Studies; Dehydroepiandrosterone; Female; Humans; | 2006 |
[Improvement in the longitudinal growth in Ullrich-Turner syndrome with oxandrolone. Function of urinary excretion of steroid hormones].
Topics: Adolescent; Adrenal Cortex Hormones; Age Determination by Skeleton; Androsterone; Body Height; Child | 1982 |
Subnormal pubertal increases of serum androgens in Turner's syndrome.
Topics: Adolescent; Adrenal Glands; Adult; Androgens; Androstenedione; Child; Child, Preschool; Dehydroepian | 1982 |
Responsiveness of cortisol and dehydroepiandrosterone to ACTH in children.
Topics: Adolescent; Adrenocorticotropic Hormone; Child; Child, Preschool; Dehydroepiandrosterone; Humans; Hy | 1982 |
Responses to constant infusion of LH-RH in girls with primary hypogonadism.
Topics: Adolescent; Adult; Androstenedione; Child; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; E | 1980 |
Effects of long-term growth hormone therapy on adrenal steroidogenesis in Turner syndrome.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Androstenedione | 1998 |
Sex hormone-binding globulin as a marker of the effect of hormonal treatment in Turner's syndrome.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Cortex Hormones; Adult; Androstenedione; Biomarker | 2001 |
Ovarian and peripheral venous steroids in XY gonadal dysgenesis and gonadoblastoma.
Topics: Adolescent; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Dysgerminoma; Estradiol; F | 1976 |
Lack of correlation between gonadotropin and adrenal androgen levels in agonadal children.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Androgens; Dehydroepiandrosterone; Estrogens, Conjugated ( | 1975 |
Replacement oral ethinyloestradiol therapy for gonadal dysgenesis: growth and adrenal androgen studies.
Topics: Administration, Oral; Adolescent; Adrenocorticotropic Hormone; Body Height; Dehydroepiandrosterone; | 1979 |
Assessment of growth hormone (GH) axis in Turner's syndrome using 24-hour integrated concentrations of GH, insulin-like growth factor-I, plasma GH-binding activity, GH binding to IM9 cells, and GH response to pharmacological stimulation.
Topics: Adolescent; Cell Line; Child; Child, Preschool; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepi | 1992 |
Adrenarche is dissociated from gonadarche--studies in patients with Turner's syndrome.
Topics: Adolescent; Adrenal Glands; Androgens; Breast; Child; Child, Preschool; Dehydroepiandrosterone; Fema | 1986 |
A modified method for the analysis of urinary 17-ketosteroids, pregnanediol and pregnanetriol by gas liquid chromatography in normal subjects and subjects with various endocrine disorders.
Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Androsterone; Chromatography, Gas; Cushing Syndrom | 1967 |
[Clinical and biochemical studies in a female patient with mixed gonadal dysgenesis].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Androsterone; Body | 1969 |
In vivo and in vitro studies of androgen metabolism in a patient with pure gonadal dysgenesis and Leydig cell hyperplasia.
Topics: 17-Hydroxycorticosteroids; Acetates; Adult; Androgens; Dehydroepiandrosterone; Female; Humans; Hydro | 1969 |
Testicular feminizing syndrome and "pure" gonadal dysgenesis. Report of cases and in vitro studies with testes homogenate.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Amenorrhea; Androgen-Insensitivity Sy | 1970 |
Steroid excretion patterns in children with gonadal dysgenesis (report of 11 cases).
Topics: 17-Hydroxycorticosteroids; Adolescent; Androsterone; Child; Child, Preschool; Chromatography, Paper; | 1970 |
C19O2 steroid secretion by dysgenetic gonads.
Topics: Adult; Androgens; Androsterone; Chromatography, Gas; Dehydroepiandrosterone; Female; Humans; Testost | 1968 |
Endocrine and metabolic studies in an XY patient with gonadal agenesis.
Topics: Adolescent; Adrenal Glands; Amenorrhea; Androstenedione; Dehydroepiandrosterone; Estradiol; Ethinyl | 1974 |
Tumors of dysgenetic gonads (gonadoblastoma): ultrastructural and steroidogenic aspects.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Androstenes; Basement Membrane; Cell Nucleus; Cytopla | 1974 |
Urinary androgens under stimulation-suppression tests in children with gonadal dysgenesis.
Topics: Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Androsterone; Chorionic Gonadotr | 1972 |