dehydroepiandrosterone has been researched along with Stress Disorders, Post-Traumatic in 40 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Stress Disorders, Post-Traumatic: A class of traumatic stress disorders with symptoms that last more than one month.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Posttraumatic stress disorder (PTSD) is associated with increased smoking initiation, maintenance, and relapse." | 5.39 | The association of dehydroepiandrosterone and dehydroepiandrosterone sulfate with anxiety sensitivity and electronic diary negative affect among smokers with and without posttraumatic stress disorder. ( Beckham, JC; Buse, NA; Calhoun, PS; Dennis, MF; McClernon, FJ; Van Voorhees, EE, 2013) |
| " At each occasion, mood, fatigue, dissociation, PTSD symptoms, short-term and working memory, and salivary cortisol and dehydroepiandrosterone (DHEA) were assessed." | 3.85 | The effects of captivity survival training on mood, dissociation, PTSD symptoms, cognitive performance and stress hormones. ( Cheung, B; Lieberman, HR; Morgan, CA; Suurd Ralph, C; Vartanian, O, 2017) |
| "A significant main effect of group (PTSD+, PTSD-, non-exposed) on the cortisol response to cosyntropin was observed." | 2.79 | Cortisol response to cosyntropin administration in military veterans with or without posttraumatic stress disorder. ( Caramanica, K; Golier, JA; Makotkine, I; Sher, L; Yehuda, R, 2014) |
| "Post-traumatic stress disorder (PTSD) has been associated with dysregulation of the neuroendocrine system." | 2.73 | Changes in cortisol and DHEA plasma levels after psychotherapy for PTSD. ( Assies, J; de Vries, GJ; Gersons, BP; Güzelcan, Y; Olff, M, 2007) |
| "Posttraumatic stress disorder (PTSD) is often associated with alterations in the hypothalamic-pituitary-adrenal (HPA) axis." | 2.61 | HPA axis regulation in posttraumatic stress disorder: A meta-analysis focusing on potential moderators. ( Cwik, JC; Engel, S; Klusmann, H; Knaevelsrud, C; Laufer, S; Niemeyer, H; Schumacher, S, 2019) |
| "Posttraumatic stress disorder (PTSD) has been associated with dysregulation of the hypothalamic-pituitary- adrenal (HPA) axis." | 2.58 | Psychotherapeutic treatment and HPA axis regulation in posttraumatic stress disorder: A systematic review and meta-analysis. ( Cwik, JC; Engel, S; Knaevelsrud, C; Niemeyer, H; Schumacher, S, 2018) |
| " This suggests that clinical trials designed to test neuroactive steroid therapeutics in PTSD may benefit from such considerations; typical continuous dosing regimens may not be optimal." | 2.55 | Neuroactive steroids and PTSD treatment. ( Liang, JJ; Locci, A; Marx, CE; Nillni, YI; Pineles, SL; Pinna, G; Rasmusson, AM; Scioli-Salter, ER, 2017) |
| "Sex influenced the effect of having PTSD on LDL with only male patients having lower values than male controls (p=0." | 1.46 | Plasma lipoproteins in posttraumatic stress disorder patients compared to healthy controls and their associations with the HPA- and HPT-axis. ( Assies, J; Mocking, R; Olff, M; Schene, A; Vries, GJ, 2017) |
| "Sexual dysfunction is not a symptom of PTSD but is a common clinical complaint in trauma survivors with this disorder." | 1.43 | Sexual dysfunction and neuroendocrine correlates of posttraumatic stress disorder in combat veterans: Preliminary findings. ( Bierer, LM; Flory, JD; Lehrner, A; Makotkine, I; Marmar, CR; Yehuda, R, 2016) |
| "Posttraumatic stress disorder (PTSD) is associated with increased morbidity and mortality through somatic conditions, particularly cardiovascular disease." | 1.42 | Altered one-carbon metabolism in posttraumatic stress disorder. ( Assies, J; de Vries, GJ; Lok, A; Mocking, R; Olff, M; Schene, A, 2015) |
| "Posttraumatic stress disorder (PTSD) is associated with increased smoking initiation, maintenance, and relapse." | 1.39 | The association of dehydroepiandrosterone and dehydroepiandrosterone sulfate with anxiety sensitivity and electronic diary negative affect among smokers with and without posttraumatic stress disorder. ( Beckham, JC; Buse, NA; Calhoun, PS; Dennis, MF; McClernon, FJ; Van Voorhees, EE, 2013) |
| "In chronic sexual abuse victims with post traumatic stress disorder (PTSD), the hypothalamic pituitary adrenal (HPA) axis can be dysregulated." | 1.39 | Salivary cortisol and dehydroepiandrosterone sulfate in adolescent rape victims with post traumatic stress disorder. ( Bicanic, IA; De Roos, C; Olff, M; Postma, RM; Sinnema, G; Van de Putte, EM; Van Wesel, F, 2013) |
| "PTSD was related to shorter time to lapse (hazard ratio [HR] = 1." | 1.39 | Predictors of lapse in first week of smoking abstinence in PTSD and non-PTSD smokers. ( Beckham, JC; Calhoun, PS; Dedert, EA; Dennis, MF; Wilson, SM, 2013) |
| "A uniform pattern of PTSD-related alterations in the response to intravenous CRF was not found." | 1.38 | Neuroendocrine response to CRF stimulation in veterans with and without PTSD in consideration of war zone era. ( Caramanica, K; Golier, JA; Yehuda, R, 2012) |
| "In 25 subjects with chronic PTSD and 25 trauma-controlled subjects, we measured the variables of metabolic syndrome supplemented by the ankle-brachial index and highly sensitive C-reactive protein." | 1.37 | Effects of chronic posttraumatic stress disorder on metabolic risk, quality of life, and stress hormones in aging former refugee children. ( Godemann, K; Goemann, C; Kellner, M; Muhtz, C; von Alm, C; Wiedemann, K; Wittekind, C; Yassouridis, A, 2011) |
| "Patients of 33 with chronic PTSD (15 with and 18 without sexual and/or severe physical abuse before age 12) were studied in a combined low dose dexamethasone/corticotropin-releasing hormone (CRH) test." | 1.36 | Increased DHEA and DHEA-S plasma levels in patients with post-traumatic stress disorder and a history of childhood abuse. ( Dunker, S; Kellner, M; Muhtz, C; Peter, F; Wiedemann, K; Yassouridis, A, 2010) |
| "Posttraumatic stress disorder (PTSD) has been associated with hypothalamic-pituitary-adrenal (HPA) axis and immune function alterations; however, few studies have simultaneously investigated these systems in participants with PTSD." | 1.35 | Low cortisol, high DHEA, and high levels of stimulated TNF-alpha, and IL-6 in women with PTSD. ( Gill, J; Page, GG; Vythilingam, M, 2008) |
| "Previous research suggests that in borderline personality disorder (BPD) normal stress regulation, with a main role for cortisol, is disturbed." | 1.34 | Basal cortisol and DHEA levels in women with borderline personality disorder. ( de Knijff, DW; Jogems-Kosterman, BJ; Kusters, R; van Hoof, JJ, 2007) |
| "Abused women with PTSD had lower concentrations of cortisol during the afternoon hours (12-8 p." | 1.34 | Cortisol, dehydroepiandrosterone, and estradiol measured over 24 hours in women with childhood sexual abuse-related posttraumatic stress disorder. ( Bremner, D; Kelley, ME; Vermetten, E, 2007) |
| "Male veterans with PTSD enrolled in a larger study during inpatient hospitalization (N=130) were assessed for suicidal ideation or suicide attempt in the last 6 months." | 1.33 | Neuroactive steroids and suicidality in posttraumatic stress disorder. ( Butterfield, MI; Connor, KM; Davidson, JR; MacKuen, CL; Marx, CE; Pearlstein, AM; Stechuchak, KM; Wang, C, 2005) |
| "In addition, among the PTSD subjects, the peak change in DHEA in response to ACTH1-24 was negatively correlated with the total Clinician Administered PTSD Scale score, while the peak DHEA to cortisol ratio was inversely associated with negative mood symptoms measured by the Profile of Mood States scale." | 1.32 | An increased capacity for adrenal DHEA release is associated with decreased avoidance and negative mood symptoms in women with PTSD. ( Charney, DS; Gudmundsen, G; Lipschitz, DS; Morgan, CA; Mustone, ME; Rasmusson, AM; Shi, Q; Vasek, J; Vojvoda, D; Wolfe, J, 2004) |
| "Our analyses suggest that chronic PTSD, particularly comorbid PTSD or complex PTSD, is associated with all of these conditions." | 1.32 | Posttraumatic stress disorder and physical illness: results from clinical and epidemiologic studies. ( Boscarino, JA, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 19 (47.50) | 29.6817 |
| 2010's | 21 (52.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suurd Ralph, C | 1 |
| Vartanian, O | 1 |
| Lieberman, HR | 1 |
| Morgan, CA | 2 |
| Cheung, B | 1 |
| van Zuiden, M | 1 |
| Haverkort, SQ | 1 |
| Tan, Z | 1 |
| Daams, J | 1 |
| Lok, A | 2 |
| Olff, M | 5 |
| Vries, GJ | 1 |
| Mocking, R | 2 |
| Assies, J | 3 |
| Schene, A | 2 |
| Budde, H | 1 |
| Akko, DP | 1 |
| Ainamani, HE | 1 |
| Murillo-Rodríguez, E | 1 |
| Weierstall, R | 1 |
| Schumacher, S | 3 |
| Niemeyer, H | 2 |
| Engel, S | 2 |
| Cwik, JC | 2 |
| Knaevelsrud, C | 2 |
| Rasmusson, AM | 5 |
| King, MW | 1 |
| Valovski, I | 1 |
| Gregor, K | 1 |
| Scioli-Salter, E | 1 |
| Pineles, SL | 2 |
| Hamouda, M | 1 |
| Nillni, YI | 2 |
| Anderson, GM | 1 |
| Pinna, G | 3 |
| Laufer, S | 1 |
| Klusmann, H | 1 |
| Van Voorhees, EE | 2 |
| Dennis, MF | 3 |
| McClernon, FJ | 1 |
| Calhoun, PS | 3 |
| Buse, NA | 1 |
| Beckham, JC | 3 |
| Golier, JA | 3 |
| Caramanica, K | 2 |
| Makotkine, I | 2 |
| Sher, L | 1 |
| Yehuda, R | 6 |
| de Vries, GJ | 2 |
| Lehrner, A | 1 |
| Flory, JD | 2 |
| Bierer, LM | 2 |
| Marmar, CR | 1 |
| Marx, CE | 2 |
| Locci, A | 1 |
| Scioli-Salter, ER | 1 |
| Liang, JJ | 1 |
| Maninger, N | 1 |
| Wolkowitz, OM | 1 |
| Reus, VI | 1 |
| Epel, ES | 1 |
| Mellon, SH | 1 |
| Gill, J | 1 |
| Vythilingam, M | 1 |
| Page, GG | 1 |
| Kellner, M | 2 |
| Muhtz, C | 2 |
| Peter, F | 1 |
| Dunker, S | 1 |
| Wiedemann, K | 2 |
| Yassouridis, A | 2 |
| Schnurr, PP | 1 |
| Zukowska, Z | 1 |
| Scioli, E | 1 |
| Forman, DE | 1 |
| Pratchett, LC | 1 |
| Pelcovitz, M | 1 |
| Godemann, K | 1 |
| von Alm, C | 1 |
| Wittekind, C | 1 |
| Goemann, C | 1 |
| Oe, M | 1 |
| Schnyder, U | 1 |
| Mueller-Pfeiffer, C | 1 |
| Wilhelm, FH | 1 |
| Kalebasi, N | 1 |
| Roos, D | 1 |
| Hersberger, M | 1 |
| Martin-Soelch, C | 1 |
| Bicanic, IA | 1 |
| Postma, RM | 1 |
| Sinnema, G | 1 |
| De Roos, C | 1 |
| Van Wesel, F | 1 |
| Van de Putte, EM | 1 |
| Wilson, SM | 1 |
| Dedert, EA | 1 |
| Vasek, J | 1 |
| Lipschitz, DS | 1 |
| Vojvoda, D | 1 |
| Mustone, ME | 1 |
| Shi, Q | 1 |
| Gudmundsen, G | 1 |
| Wolfe, J | 1 |
| Charney, DS | 2 |
| Pico-Alfonso, MA | 1 |
| Garcia-Linares, MI | 1 |
| Celda-Navarro, N | 1 |
| Herbert, J | 1 |
| Martinez, M | 1 |
| Boscarino, JA | 1 |
| Butterfield, MI | 1 |
| Stechuchak, KM | 1 |
| Connor, KM | 1 |
| Davidson, JR | 1 |
| Wang, C | 1 |
| MacKuen, CL | 1 |
| Pearlstein, AM | 1 |
| Avital, A | 1 |
| Ram, E | 1 |
| Maayan, R | 2 |
| Weizman, A | 1 |
| Richter-Levin, G | 1 |
| Sageman, S | 1 |
| Brown, RP | 1 |
| Cohen, H | 1 |
| Touati-Werner, D | 1 |
| Kaplan, Z | 1 |
| A Matar, M | 1 |
| Loewenthal, U | 1 |
| Kozlovsky, N | 1 |
| Weizman, R | 1 |
| Brand, SR | 1 |
| Yang, RK | 1 |
| Hoge, EA | 1 |
| Austin, ED | 1 |
| Pollack, MH | 1 |
| Paliwal, P | 1 |
| Weisman, D | 1 |
| Gottschalk, C | 1 |
| Charney, D | 1 |
| Krystal, J | 1 |
| Guidotti, A | 1 |
| Jogems-Kosterman, BJ | 1 |
| de Knijff, DW | 1 |
| Kusters, R | 1 |
| van Hoof, JJ | 1 |
| Glover, DA | 1 |
| Stuber, M | 1 |
| Poland, RE | 1 |
| Güzelcan, Y | 1 |
| Gersons, BP | 1 |
| Haglund, ME | 1 |
| Nestadt, PS | 1 |
| Cooper, NS | 1 |
| Southwick, SM | 1 |
| Bremner, D | 1 |
| Vermetten, E | 1 |
| Kelley, ME | 1 |
| Kanter, ED | 1 |
| Wilkinson, CW | 1 |
| Radant, AD | 1 |
| Petrie, EC | 1 |
| Dobie, DJ | 1 |
| McFall, ME | 1 |
| Peskind, ER | 1 |
| Raskind, MA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness of Prazosin in Bulimic Patients Experiencing Nightmares Due to PTSD[NCT02382848] | 9 participants (Actual) | Interventional | 2015-07-31 | Completed | |||
| Longitudinal Measurement of Cortisol in Association With Mental Health and Experience of Domestic Violence and Abuse[NCT01632553] | 214 participants (Actual) | Observational | 2012-08-31 | Completed | |||
| The Efficacy of a Single Dose IV Hydrocortisone Given Within 6 Hours of Exposure to a Traumatic Event in PTSD Prevention[NCT00855270] | 120 participants (Anticipated) | Interventional | 2009-04-30 | Recruiting | |||
| Effects of Pregnenolone on Perceived Social Isolation: A Double-blind Randomized Electrical Neuroimaging Study[NCT02826577] | Phase 2 | 96 participants (Anticipated) | Interventional | 2017-05-01 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
EDI-3 (Eating Disorder Inventory 3 Scale) is a pencil and paper test consisting of 91 items and 12 sub-scales. The main scales are the drive for thinness and the bulimia scales, the remaining sub-scales are: low self-esteem, body dissatisfaction, maturity fears, personal alienation, interpersonal alienation, interpersonal insecurity, perfectionism, interoceptive deficits, emotional dysregulation, and asceticism. The response options are based on a 6-point Likert-type scale are: Always, Usually, Often, Sometimes, Rarely, and Never. There are six composite scores, 12 primary scores, and three response style validity indicators. Software is used to calculate the raw scores, composite scores, validity scale scores and the T-scores. The t-score for the Bulimia scale will be used for this analysis with a range of 22-66. Higher scores indicate the likelihood of an eating disorder. A higher t-score on the bulimia scale indicates a worse outcome. (NCT02382848)
Timeframe: 3 weeks
| Intervention | T-Score (Mean) |
|---|---|
| Prazosin | 43.1 |
| Placebo | 38.6 |
Rating scales and subject interview will be used to determine if there is a decrease in depressed mood among participants undergoing drug intervention. The HDRS (Hamilton Depression Rating Scale) consists of 17 items, some scored on a 5-point scale (0-4) and others scored on a 3-point scale (0-2). Items from the scale can be summed to give a total score ranging from 0 to 50, with higher scores indicating a worse outcome. This analysis is based on a single item from the scale (Depressed Mood, measured on a 5-point scale) where a higher score again indicates a worse outcome. (NCT02382848)
Timeframe: 3 weeks
| Intervention | score on a scale (Mean) |
|---|---|
| Prazosin | 1.4 |
| Placebo | 1.3 |
"The individual question about frightening dreams from the Nightmares Subscale of a self-administered questionnaire (Sleep-50 Questionnaire), will be used to determine if there is a decrease in frequency of nightmares in patients undergoing drug intervention. For each question, respondents are provided with a scale ranging from 1 (not at all) to 4 (very much) and are asked to indicate the extent to which the statement has matched their experience over the study time frame. The scale values range from 1-4, where a lower value indicates lower frequency of nightmares. A higher score is a worse outcome." (NCT02382848)
Timeframe: 3 weeks
| Intervention | score on a scale (Mean) |
|---|---|
| Prazosin | 2.25 |
| Placebo | 2.75 |
Rating scales and subject interview will be used to determine if there is a decrease in self harm among participants undergoing drug intervention. The HDRS (Hamilton Depression Rating Scale) consists of 17 items, some scored on a 5-point scale (0-4) and others scored on a 3-point scale (0-2). Items from the scale can be summed to give a total score ranging from 0 to 50, with higher scores indicating a worse outcome. This analysis is based on a single item from the scale (Self Harm, measured on a 5-point scale) where a higher score again indicates a worse outcome. (NCT02382848)
Timeframe: 3 weeks
| Intervention | score on a scale (Mean) |
|---|---|
| Prazosin | 0.5 |
| Placebo | .1 |
The CAPS (Clinician administered PTSD) rating scale consists of 30 questions rated on a 0-4 point scoring system and patient interview will be used to determine if there is a decrease in PTSD Symptoms among participants undergoing drug intervention. 17 of these questions are used to calculate the total severity score used in this analysis. This is done by summing the frequency and intensity ratings (each ranging from 0-4) for each of the 17 questions. The total severity score can have a range of 0-136. A higher score on this scale indicates a worse outcome. (NCT02382848)
Timeframe: 3 weeks
| Intervention | score on a scale (Mean) |
|---|---|
| Prazosin | 65.5 |
| Placebo | 79.8 |
7 reviews available for dehydroepiandrosterone and Stress Disorders, Post-Traumatic
| Article | Year |
|---|---|
DHEA and DHEA-S levels in posttraumatic stress disorder: A meta-analytic review.
Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Glucocorticoids; Humans; Hydrocortis | 2017 |
Psychotherapeutic treatment and HPA axis regulation in posttraumatic stress disorder: A systematic review and meta-analysis.
Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Hydrocortisone; Hypothalamo-Hypophys | 2018 |
HPA axis regulation in posttraumatic stress disorder: A meta-analysis focusing on potential moderators.
Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Hydrocortisone; Hypothalamo-Hypophys | 2019 |
Neuroactive steroids and PTSD treatment.
Topics: Animals; Dehydroepiandrosterone; Estradiol; Glucocorticoids; Humans; Pregnanolone; Steroids; Stress | 2017 |
Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS).
Topics: Adult; Aged; Aging; Animals; Antioxidants; Brain; Dehydroepiandrosterone; Dehydroepiandrosterone Sul | 2009 |
Adaptation to extreme stress: post-traumatic stress disorder, neuropeptide Y and metabolic syndrome.
Topics: Adaptation, Physiological; Animals; Dehydroepiandrosterone; Female; Glucocorticoids; Humans; Hydroco | 2010 |
Resilience: research evidence and conceptual considerations for posttraumatic stress disorder.
Topics: Adaptation, Psychological; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Hydrocort | 2007 |
3 trials available for dehydroepiandrosterone and Stress Disorders, Post-Traumatic
| Article | Year |
|---|---|
The impact of an exercise training intervention on cortisol levels and post-traumatic stress disorder in juveniles from an Ugandan refugee settlement: study protocol for a randomized control trial.
Topics: Adolescent; Dehydroepiandrosterone; Ethics Committees, Clinical; Exercise; Exercise Therapy; Humans; | 2018 |
Cortisol response to cosyntropin administration in military veterans with or without posttraumatic stress disorder.
Topics: Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Cosyntropin; Dehydroepiandroste | 2014 |
Changes in cortisol and DHEA plasma levels after psychotherapy for PTSD.
Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Life | 2007 |
30 other studies available for dehydroepiandrosterone and Stress Disorders, Post-Traumatic
| Article | Year |
|---|---|
The effects of captivity survival training on mood, dissociation, PTSD symptoms, cognitive performance and stress hormones.
Topics: Adult; Affect; Anxiety; Combat Disorders; Dehydroepiandrosterone; Dissociative Disorders; Fatigue; F | 2017 |
Plasma lipoproteins in posttraumatic stress disorder patients compared to healthy controls and their associations with the HPA- and HPT-axis.
Topics: Adult; Cardiovascular Diseases; Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Cross-Sect | 2017 |
Relationships between cerebrospinal fluid GABAergic neurosteroid levels and symptom severity in men with PTSD.
Topics: 5-alpha-Dihydroprogesterone; Adult; Cholestenone 5 alpha-Reductase; Dehydroepiandrosterone; Dehydroe | 2019 |
The association of dehydroepiandrosterone and dehydroepiandrosterone sulfate with anxiety sensitivity and electronic diary negative affect among smokers with and without posttraumatic stress disorder.
Topics: Adult; Affect; Anxiety; Biomarkers; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; | 2013 |
Association of DHEA, DHEAS, and cortisol with childhood trauma exposure and post-traumatic stress disorder.
Topics: Adult; Child; Child Abuse; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depressive Disord | 2014 |
Altered one-carbon metabolism in posttraumatic stress disorder.
Topics: Adult; Case-Control Studies; Dehydroepiandrosterone; Depression; Female; Folic Acid; Homocysteine; H | 2015 |
Sexual dysfunction and neuroendocrine correlates of posttraumatic stress disorder in combat veterans: Preliminary findings.
Topics: Adult; Combat Disorders; Comorbidity; Cross-Sectional Studies; Dehydroepiandrosterone; Depressive Di | 2016 |
Low cortisol, high DHEA, and high levels of stimulated TNF-alpha, and IL-6 in women with PTSD.
Topics: Adult; Baltimore; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Interleukin-6; Interviews | 2008 |
Increased DHEA and DHEA-S plasma levels in patients with post-traumatic stress disorder and a history of childhood abuse.
Topics: Adult; Adult Survivors of Child Abuse; Area Under Curve; Corticotropin-Releasing Hormone; Dehydroepi | 2010 |
Using biological markers to inform a clinically meaningful treatment response.
Topics: Biomarkers; Dehydroepiandrosterone; Humans; Implosive Therapy; Receptors, Glucocorticoid; Stress Dis | 2010 |
Neuroendocrine response to CRF stimulation in veterans with and without PTSD in consideration of war zone era.
Topics: Adrenocorticotropic Hormone; Adult; Afghan Campaign 2001-; Carrier Proteins; Corticotropin-Releasing | 2012 |
Effects of chronic posttraumatic stress disorder on metabolic risk, quality of life, and stress hormones in aging former refugee children.
Topics: Adrenocorticotropic Hormone; Aged; Ankle Brachial Index; C-Reactive Protein; Dehydroepiandrosterone; | 2011 |
Lower plasma dehydroepiandrosterone concentration in the long term after severe accidental injury.
Topics: Accidents; Adjuvants, Immunologic; Case-Control Studies; Dehydroepiandrosterone; Female; Humans; Mal | 2012 |
Salivary cortisol and dehydroepiandrosterone sulfate in adolescent rape victims with post traumatic stress disorder.
Topics: Adolescent; Adolescent Behavior; Case-Control Studies; Crime Victims; Dehydroepiandrosterone; Depres | 2013 |
Predictors of lapse in first week of smoking abstinence in PTSD and non-PTSD smokers.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfat | 2013 |
An increased capacity for adrenal DHEA release is associated with decreased avoidance and negative mood symptoms in women with PTSD.
Topics: Adrenal Glands; Adult; Aging; Behavior; Cosyntropin; Dehydroepiandrosterone; Dehydroepiandrosterone | 2004 |
Changes in cortisol and dehydroepiandrosterone in women victims of physical and psychological intimate partner violence.
Topics: Adult; Analysis of Variance; Anxiety; Battered Women; Crime Victims; Dehydroepiandrosterone; Depress | 2004 |
Posttraumatic stress disorder and physical illness: results from clinical and epidemiologic studies.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Dehydroepiandrosterone; Diabetes Mellitus, Type 1; Femal | 2004 |
Neuroactive steroids and suicidality in posttraumatic stress disorder.
Topics: Androstenedione; Dehydroepiandrosterone; Estradiol; Humans; Male; Middle Aged; Self-Injurious Behavi | 2005 |
Effects of early-life stress on behavior and neurosteroid levels in the rat hypothalamus and entorhinal cortex.
Topics: Affective Symptoms; Age Factors; Animals; Cognition Disorders; Dehydroepiandrosterone; Dehydroepiand | 2006 |
3-acetyl-7-oxo-dehydroepiandrosterone for healing treatment-resistant posttraumatic stress disorder in women: 5 case reports.
Topics: Adult; Chronic Disease; Dehydroepiandrosterone; Drug Resistance; Female; Humans; Life Change Events; | 2006 |
Decreased circulatory levels of neuroactive steroids in behaviourally more extremely affected rats subsequent to exposure to a potentially traumatic experience.
Topics: Acoustic Stimulation; Animals; Anxiety; Behavior, Animal; Circadian Rhythm; Corticosterone; Dehydroe | 2007 |
Clinical correlates of DHEA associated with post-traumatic stress disorder.
Topics: Adaptation, Psychological; Aged; Aged, 80 and over; Arousal; Combat Disorders; Defense Mechanisms; D | 2006 |
Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder.
Topics: 5-alpha-Dihydroprogesterone; Adult; Affect; Analysis of Variance; Dehydroepiandrosterone; Female; Hu | 2006 |
Basal cortisol and DHEA levels in women with borderline personality disorder.
Topics: Adaptation, Psychological; Adult; Borderline Personality Disorder; Child; Child Abuse; Dehydroepiand | 2007 |
Allostatic load in women with and without PTSD symptoms.
Topics: Adolescent; Adult; Allostasis; Arousal; Blood Pressure; Body Mass Index; Child; Child, Preschool; Ch | 2006 |
Psychobiological mechanisms of resilience: relevance to prevention and treatment of stress-related psychopathology.
Topics: Adaptation, Psychological; Child; Corticotropin-Releasing Hormone; Dehydroepiandrosterone; Dopamine; | 2007 |
Differentiating biological correlates of risk, PTSD, and resilience following trauma exposure.
Topics: Adaptation, Psychological; Aged; Aged, 80 and over; Combat Disorders; Dehydroepiandrosterone; Hippoc | 2007 |
Cortisol, dehydroepiandrosterone, and estradiol measured over 24 hours in women with childhood sexual abuse-related posttraumatic stress disorder.
Topics: Adolescent; Adult; Bulimia; Child; Child Abuse, Sexual; Child, Preschool; Circadian Rhythm; Comorbid | 2007 |
Glucocorticoid feedback sensitivity and adrenocortical responsiveness in posttraumatic stress disorder.
Topics: Adrenocorticotropic Hormone; Dehydroepiandrosterone; Feedback; Humans; Hydrocortisone; Hypothalamo-H | 2001 |