Page last updated: 2024-11-07

dehydroepiandrosterone and Spinal Cord Injuries

dehydroepiandrosterone has been researched along with Spinal Cord Injuries in 8 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).

Research Excerpts

ExcerptRelevanceReference
" Progesterone and dehydroepiandrosterone (DHEA) are neuroactive steroids that modulate neuronal and astroglial function and have neuroprotective effects in different experimental models, being potential candidates to the development of new therapeutic approaches for brain and spinal cord injuries."4.93Astrocytes as a target for neuroprotection: Modulation by progesterone and dehydroepiandrosterone. ( Arbo, BD; Bennetti, F; Ribeiro, MF, 2016)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arbo, BD2
Ribeiro, FS1
Ribeiro, MF2
Bennetti, F1
Teshigawara, K1
Kuboyama, T1
Shigyo, M1
Nagata, A1
Sugimoto, K1
Matsuya, Y1
Tohda, C1
Fiore, C1
Inman, DM1
Hirose, S1
Noble, LJ1
Igarashi, T1
Compagnone, NA1
Mure, PY1
Galdo, M1
Compagnone, N1
Rouleau, P1
Ung, RV1
Lapointe, NP1
Guertin, PA1
Guth, L1
Zhang, Z1
Roberts, E1
Romanova, VM1

Reviews

2 reviews available for dehydroepiandrosterone and Spinal Cord Injuries

ArticleYear
Astrocyte Neuroprotection and Dehydroepiandrosterone.
    Vitamins and hormones, 2018, Volume: 108

    Topics: Animals; Astrocytes; Brain Injuries, Traumatic; Dehydroepiandrosterone; Humans; Neurodegenerative Di

2018
Astrocytes as a target for neuroprotection: Modulation by progesterone and dehydroepiandrosterone.
    Progress in neurobiology, 2016, Volume: 144

    Topics: Animals; Astrocytes; Brain Injuries; Dehydroepiandrosterone; Humans; Neuroprotection; Progesterone;

2016

Other Studies

6 other studies available for dehydroepiandrosterone and Spinal Cord Injuries

ArticleYear
A novel compound, denosomin, ameliorates spinal cord injury via axonal growth associated with astrocyte-secreted vimentin.
    British journal of pharmacology, 2013, Volume: 168, Issue:4

    Topics: Animals; Astrocytes; Axons; Cicatrix; Dehydroepiandrosterone; Disease Models, Animal; Male; Mice; Mi

2013
Treatment with the neurosteroid dehydroepiandrosterone promotes recovery of motor behavior after moderate contusive spinal cord injury in the mouse.
    Journal of neuroscience research, 2004, Feb-01, Volume: 75, Issue:3

    Topics: Animals; Dehydroepiandrosterone; Female; Glial Fibrillary Acidic Protein; Immunohistochemistry; Mice

2004
Bladder function after incomplete spinal cord injury in mice: quantifiable outcomes associated with bladder function and efficiency of dehydroepiandrosterone as a therapeutic adjunct.
    Journal of neurosurgery, 2004, Volume: 100, Issue:1 Suppl Sp

    Topics: Animals; Collagen Type III; Dehydroepiandrosterone; Female; Mice; Microscopy, Fluorescence; Motor Ac

2004
Hormonal and immunological changes in mice after spinal cord injury.
    Journal of neurotrauma, 2007, Volume: 24, Issue:2

    Topics: Animals; Blood Cell Count; Bone Marrow Cells; Dehydroepiandrosterone; Disease Models, Animal; Human

2007
Key role for pregnenolone in combination therapy that promotes recovery after spinal cord injury.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Dec-06, Volume: 91, Issue:25

    Topics: Analysis of Variance; Animals; Aspirin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Doub

1994
[State of the hypothalamus-hypophysis-adrenal-cortex system in children with aftereffects of birth injuries of the spinal cord].
    Pediatriia, 1975, Issue:12

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex; Adrenal Glands; Birth Injuri

1975