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dehydroepiandrosterone and Skin Neoplasms

dehydroepiandrosterone has been researched along with Skin Neoplasms in 11 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Skin Neoplasms: Tumors or cancer of the SKIN.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study is to report on Aminoglutethimide-induced hormonal modifications in advanced breast cancer."7.67Preliminary study of hormone determinations during aminoglutethimide therapy for advanced breast cancer. ( Díaz, L; Koliren, L; Loruso, A; Ramos, G; Scaglia, HE; Soto, E; Zylbersztein, C, 1984)
"Topical application of the adrenal steroid, dehydroepiandrosterone, or the synthetic steroid, 3-beta-methylandrost-5-en-17-one, which unlike dehydroepiandrosterone is not demonstrably uterotrophic, inhibits 7,12-dimethylbenz(a)anthracene-induced skin papillomas and carcinomas in the CD-1 mouse."7.67Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin papillomas and carcinomas by dehydroepiandrosterone and 3-beta-methylandrost-5-en-17-one in mice. ( Hard, GC; Pashko, LL; Rovito, RJ; Schwartz, AG; Sobel, EL; Williams, JR, 1985)
"The aim of this study is to report on Aminoglutethimide-induced hormonal modifications in advanced breast cancer."3.67Preliminary study of hormone determinations during aminoglutethimide therapy for advanced breast cancer. ( Díaz, L; Koliren, L; Loruso, A; Ramos, G; Scaglia, HE; Soto, E; Zylbersztein, C, 1984)
"Topical application of the adrenal steroid, dehydroepiandrosterone, or the synthetic steroid, 3-beta-methylandrost-5-en-17-one, which unlike dehydroepiandrosterone is not demonstrably uterotrophic, inhibits 7,12-dimethylbenz(a)anthracene-induced skin papillomas and carcinomas in the CD-1 mouse."3.67Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin papillomas and carcinomas by dehydroepiandrosterone and 3-beta-methylandrost-5-en-17-one in mice. ( Hard, GC; Pashko, LL; Rovito, RJ; Schwartz, AG; Sobel, EL; Williams, JR, 1985)
"Dehydroepiandrosterone (DHEA) is an adrenocortical steroid that produces broad-spectrum cancer chemopreventive action in mice and rats."2.38Cancer chemoprevention with the adrenocortical steroid dehydroepiandrosterone and structural analogs. ( Pashko, LL; Schwartz, AG, 1993)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's4 (36.36)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pashko, LL7
Rovito, RJ2
Williams, JR2
Sobel, EL2
Schwartz, AG7
Scaglia, HE1
Koliren, L1
Loruso, A1
Zylbersztein, C1
Ramos, G1
Díaz, L1
Soto, E1
Marković, L1
Ivanović, S1
Konstantinović, I1
Ikić, D1
Micić, J1
Stakić, B1
Fairman, DK1
Polansky, M1
Lewbart, ML1
Nishino, H1
Hard, GC1
Leung, BS1
Fletcher, WS1
Lindell, TD1
Wood, DC1
Krippaechne, WW1

Reviews

3 reviews available for dehydroepiandrosterone and Skin Neoplasms

ArticleYear
Cancer chemoprevention with the adrenocortical steroid dehydroepiandrosterone and structural analogs.
    Journal of cellular biochemistry. Supplement, 1993, Volume: 17G

    Topics: Adrenal Cortex; Animals; Antineoplastic Agents; Dehydroepiandrosterone; Glucosephosphate Dehydrogena

1993
Cancer prevention with dehydroepiandrosterone and non-androgenic structural analogs.
    Journal of cellular biochemistry. Supplement, 1995, Volume: 22

    Topics: Adrenal Cortex Hormones; Androgens; Animals; Anticarcinogenic Agents; Cell Division; Dehydroepiandro

1995
Mechanism of cancer preventive action of DHEA. Role of glucose-6-phosphate dehydrogenase.
    Annals of the New York Academy of Sciences, 1995, Dec-29, Volume: 774

    Topics: Adrenalectomy; Animals; Dehydroepiandrosterone; Energy Intake; Female; Glucosephosphate Dehydrogenas

1995

Other Studies

8 other studies available for dehydroepiandrosterone and Skin Neoplasms

ArticleYear
Dehydroepiandrosterone (DHEA) and 3 beta-methylandrost-5-en-17-one: inhibitors of 7,12-dimethylbenz[a]anthracene (DMBA)-initiated and 12-O-tetradecanoylphorbol-13-acetate (TPA)-promoted skin papilloma formation in mice.
    Carcinogenesis, 1984, Volume: 5, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenes; Animals; Benz(a)Anthracenes; Dehydroepiandrosterone;

1984
Preliminary study of hormone determinations during aminoglutethimide therapy for advanced breast cancer.
    European journal of gynaecological oncology, 1984, Volume: 5, Issue:3

    Topics: Adult; Aged; Aldosterone; Aminoglutethimide; Bone Neoplasms; Breast Neoplasms; Dehydroepiandrosteron

1984
Influence of interferon on C19-steroids in urine of malignant skin melanoma and malignant breast neoplasm patients.
    International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:8

    Topics: Adult; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Interferon Type I; Male; Melanoma;

1984
Reversal of food restriction-induced inhibition of mouse skin tumor promotion by adrenalectomy.
    Carcinogenesis, 1992, Volume: 13, Issue:10

    Topics: Adrenal Glands; Adrenalectomy; Animals; Body Weight; Corticosterone; Dehydroepiandrosterone; DNA, Ne

1992
Inhibition of 7,12-dimethylbenz[a]anthracene-initiated and 12-O-tetradecanoylphorbol-13-acetate-promoted skin papilloma formation in mice by dehydroepiandrosterone and two synthetic analogs.
    Carcinogenesis, 1989, Volume: 10, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Weight; Dehydroepiandrosteron

1989
[Mechanism of tumor promotion].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1988, Volume: 182, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calmodulin;

1988
Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin papillomas and carcinomas by dehydroepiandrosterone and 3-beta-methylandrost-5-en-17-one in mice.
    Cancer research, 1985, Volume: 45, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Androstenes; Animals; Antineoplastic Agen

1985
Predictability of response to endocrine ablation in advanced breast carcinoma. A correlation to estrogen receptor and steroid sulfurylation.
    Archives of surgery (Chicago, Ill. : 1960), 1973, Volume: 106, Issue:4

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Breast Neoplasms; Dehydroepiandrosterone; Estra

1973