dehydroepiandrosterone has been researched along with Skin Aging in 7 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Skin Aging: The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dehydroepiandrosterone (DHEA) is a steroid hormone involved in physiological aging." | 2.73 | Effects of topical DHEA on aging skin: a pilot study. ( Baldo, F; Bastien, P; de Lacharriere, O; Nouveau, S, 2008) |
| "Intrinsic skin aging is determined primarily by genetic factors and hormonal status." | 1.32 | [Intrinsic skin aging. A critical appraisal of the role of hormones]. ( Zouboulis, ChC, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| El-Alfy, M | 1 |
| Deloche, C | 1 |
| Azzi, L | 1 |
| Bernard, BA | 1 |
| Bernerd, F | 1 |
| Coutet, J | 1 |
| Chaussade, V | 1 |
| Martel, C | 1 |
| Leclaire, J | 1 |
| Labrie, F | 1 |
| Zouboulis, ChC | 1 |
| Nouveau, S | 1 |
| Bastien, P | 1 |
| Baldo, F | 1 |
| de Lacharriere, O | 1 |
| Lee, KS | 1 |
| Oh, KY | 1 |
| Kim, BC | 1 |
| Purba, MB | 1 |
| Kouris-Blazos, A | 1 |
| Wattanapenpaiboon, N | 1 |
| Lukito, W | 1 |
| Rothenberg, E | 1 |
| Steen, B | 1 |
| Wahlqvist, ML | 1 |
| Phillips, TJ | 1 |
| Demircay, Z | 1 |
| Sahu, M | 1 |
| Lipsker, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessment and Augmentation of Lip Appearance in Specific Study Populations[NCT04839692] | Phase 4 | 37 participants (Actual) | Interventional | 2021-05-07 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Pre and post-treatment lip vessel thickness was measured in µm using Optical Coherence Tomography-Angiography imaging. For each age group, pre and post-treatment means were calculated.~The difference between the post and the pre-treatment means is shown below (post-treatment mean - pre-treatment mean)." (NCT04839692)
Timeframe: Day 1 and Day 14
| Intervention | µm (Mean) |
|---|---|
| Young Females (21-30 Years Old) | 0.833 |
| Post Menopausal Females | 0.360 |
"The Lip Fullness Grading Scale was used to measure the size of the lips before and after the procedure in both groups. The result presented below is the difference between the means after and before the procedures for each group.~min value: 0 - very thin lips - worse outcome Max value: 4 - full lips- a better outcome" (NCT04839692)
Timeframe: D1 and D14
| Intervention | units on a scale (Mean) |
|---|---|
| Young Females (21-30 Years Old) | 1.14 |
| Post Menopausal Females | 0.78 |
This scale will be used to record the subject's overall pain from the procedure. There are 6 faces ranging from 0=no pain to 10=the worst pain. (NCT04839692)
Timeframe: Day 1
| Intervention | score on a scale (Mean) |
|---|---|
| Young Females (21-30 Years Old) | 2.9 |
| Post Menopausal Females | 3.5 |
1 review available for dehydroepiandrosterone and Skin Aging
| Article | Year |
|---|---|
Hormonal effects on skin aging.
Topics: Dehydroepiandrosterone; Estrogens; Female; Growth Hormone; Hormone Replacement Therapy; Hot Flashes; | 2001 |
2 trials available for dehydroepiandrosterone and Skin Aging
| Article | Year |
|---|---|
Skin responses to topical dehydroepiandrosterone: implications in antiageing treatment?
Topics: Administration, Topical; Aged; Biopsy; Dehydroepiandrosterone; Dermatologic Agents; Dermis; Epidermi | 2010 |
Effects of topical DHEA on aging skin: a pilot study.
Topics: Adjuvants, Immunologic; Administration, Topical; Aged; Atrophy; Dehydroepiandrosterone; Double-Blind | 2008 |
4 other studies available for dehydroepiandrosterone and Skin Aging
| Article | Year |
|---|---|
[Intrinsic skin aging. A critical appraisal of the role of hormones].
Topics: Administration, Topical; Adolescent; Adult; Age Factors; Aged; Androgens; Antioxidants; Chemexfoliat | 2003 |
Effects of dehydroepiandrosterone on collagen and collagenase gene expression by skin fibroblasts in culture.
Topics: Adult; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Collagen; Collagenases; Dehydroepiandro | 2000 |
Can skin wrinkling in a site that has received limited sun exposure be used as a marker of health status and biological age?
Topics: Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Dehydroepiandrosterone; Female; Geriatric A | 2001 |
[Is DHEA useful?].
Topics: Dehydroepiandrosterone; Humans; Skin Aging | 2001 |