Page last updated: 2024-11-07

dehydroepiandrosterone and Sex Disorders

dehydroepiandrosterone has been researched along with Sex Disorders in 39 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Research Excerpts

ExcerptRelevanceReference
" Topical interventions (vaginal gels or creams) were able to alleviate vaginal dryness and dyspareunia, with intravaginal dehydroepiandrosterone (DHEA) (6."5.22Efficacy of interventions to manage sexual dysfunction in women with cancer: a systematic review. ( Febrina, F; Marino, JL; Peate, M; Triyoga, IF; White, M, 2022)
" Vaginal estrogen preparations with the lowest systemic absorption rate may be preferred in women with history of breast cancer and severe vaginal atrophy."2.48Management of vulvovaginal atrophy-related sexual dysfunction in postmenopausal women: an up-to-date review. ( Bradshaw, K; Carr, BR; Tan, O, 2012)
" Moreover; a low dose treatment with a minimised systemic absorption rate may be considered in women with a history of breast cancer and associated severe vulvovaginal atrophy."2.48[Local estrogen therapy--clinical implications--2012 update]. ( Bartuzi, A; Kokot-Kierepa, M; Kulik-Rechberger, B; Rechberger, T, 2012)
"Dehydroepiandrosterone (DHEA) is an abundant circulating androgen precursor preferentially produced by the adrenal glands."2.43Dehydroepiandrosterone therapy as female androgen replacement. ( Guay, A; Saltzman, E, 2006)
" This paper includes practical considerations on dosage to be used, contraindications and follow-up."2.42Androgen therapy with dehydroepiandrosterone. ( Buvat, J, 2003)
"Polycystic ovarian syndrome and hypogonadotropic hypogonadism occurred significantly more often in women with TLE than in the general female population."1.27Reproductive endocrine disorders in women with partial seizures of temporal lobe origin. ( Geschwind, N; Herzog, AG; Schomer, DL; Seibel, MM; Vaitukaitis, JL, 1986)
"The effect of long-term administration of digoxin on sexual dysfunction was investigated in correlation to plasma androgens level."1.27The effect of long-term administration of digoxin on plasma androgens and sexual dysfunction. ( Aygen, M; Kaufman, H; Lidor, Y; Neri, A; Zukerman, Z, 1987)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19906 (15.38)18.7374
1990's1 (2.56)18.2507
2000's11 (28.21)29.6817
2010's19 (48.72)24.3611
2020's2 (5.13)2.80

Authors

AuthorsStudies
Febrina, F1
Triyoga, IF1
White, M1
Marino, JL1
Peate, M1
Basson, R5
Sauer, U1
Talaulikar, V1
Davies, MC1
O'Loughlin, JI1
Weinberg, J1
Young, AH1
Bodnar, T1
Brotto, LA1
Davis, SR4
Pluchino, N1
Carmignani, A1
Cubeddu, A1
Santoro, A1
Cela, V1
Errasti, T1
Alcalà, TE1
Bertin, J1
Dury, AY1
Ouellet, J2
Pelletier, G2
Labrie, F4
Zimmerman, Y1
Foidart, JM1
Pintiaux, A1
Minon, JM1
Fauser, BC1
Cobey, K1
Coelingh Bennink, HJ1
Eden, JA1
Bouchard, C1
Derogatis, L1
Girard, G1
Ayotte, N1
Gallagher, J1
Cusan, L1
Archer, DF1
Portman, D1
Lavoie, L1
Beauregard, A1
Côté, I1
Martel, C2
Vaillancourt, M1
Balser, J1
Moyneur, E1
Worsley, R1
Miller, KK1
Parish, SJ1
Santoro, N1
Farmer, M1
Yoon, H1
Goldstein, I1
Peixoto, C1
Carrilho, CG1
Barros, JA1
Ribeiro, TT1
Silva, LM1
Nardi, AE1
Cardoso, A1
Veras, AB1
Panjari, M2
Bell, R1
Adams, J1
Morrow, C1
Papalia, MA2
Astbury, J1
Morales, A1
Black, A1
Emerson, L1
Barkin, J1
Kuzmarov, I1
Day, A1
Wierman, ME1
van Lankveld, J1
Brotto, L1
Simon, JA1
Tan, O1
Bradshaw, K1
Carr, BR1
Maggi, M1
Buvat, J2
Corona, G1
Guay, A2
Torres, LO1
Kokot-Kierepa, M1
Bartuzi, A1
Kulik-Rechberger, B1
Rechberger, T1
Belaisch, J1
Johnson, CE1
Berman, JR1
Burger, H1
Saltzman, E1
Bachmann, G1
Oza, D1
Bácsi, K1
Kósa, J1
Lazáry, A1
Horváth, H1
Balla, B1
Lakatos, P1
Speer, G1
Abrahamsson, L1
Hackl, H1
Orstam, S1
Lafisca, S1
Bolelli, G1
Franceschetti, F1
Filicori, M1
Flamigni, C1
Marigo, M1
Sutcliffe, RG1
Russell, AJ1
Edwards, CR1
Wallace, AM1
Herzog, AG1
Seibel, MM1
Schomer, DL1
Vaitukaitis, JL1
Geschwind, N1
Neri, A1
Zukerman, Z1
Aygen, M1
Lidor, Y1
Kaufman, H1
Bannister, P1
Oakes, J1
Sheridan, P1
Losowsky, MS1
Borghi, A1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Open-Label Vulvoscopy Photography Study of Changes in Vulva, Vestibule, Urethral Meatus and Vagina 20 Weeks Post Daily Administration of 6.5 Mg Vaginal Prasterone in Menopausal Women With Moderate to Severe Dyspareunia[NCT03568604]Phase 418 participants (Actual)Interventional2018-08-07Completed
DHEA Against Vaginal Atrophy - Safety Study of 12 Months[NCT01256671]Phase 3530 participants (Actual)Interventional2010-12-31Completed
Prasterone (DHEA) for the Treatment of Hypoactive Sexual Desire Disorder (HSDD) - Second Study (Placebo-Controlled, Double-Blind and Randomized Phase III Study of Intravaginal Prasterone)[NCT03619005]Phase 30 participants (Actual)Interventional2018-11-13Withdrawn (stopped due to Business decision to not continue this study (only few subjects were screened).)
Prasterone (DHEA) for the Treatment of Hypoactive Sexual Desire Disorder (HSDD) - (Placebo-Controlled, Double Blind and Randomized Phase III Study of Intravaginal Prasterone)[NCT03287232]Phase 3653 participants (Actual)Interventional2017-10-16Completed
Thermal Treatment of Vulvo-vaginal Atrophy (VVA) Using Novel Low-energy Dynamic Quadripolar Radio-Frequency (DQRF)[NCT03857893]53 participants (Actual)Interventional2019-03-01Terminated (stopped due to The study was delayed due to the Covid 19 pandemic. The study was stopped prematurely due to a lack of efficiency (reported by the patients))
Effect of Combined Antihypertensive Therapy on Blood Pressure and Sexual Function in Patients With Essential Hypertension[NCT01238705]Phase 4280 participants (Anticipated)Interventional2008-04-30Recruiting
Analgesic Efficacy of Testosterone Replacement in Hypogonadal Opioid-treated Chronic Pain Patients: A Pilot Study.[NCT00398034]Phase 20 participants (Actual)Interventional2006-10-30Withdrawn (stopped due to The original PI (David Siegel) Left the VA)
Effect of Type and Severity of Liver Cirrhosis on Semen Parameters and Reproductive Hormones[NCT03167749]90 participants (Anticipated)Observational2018-01-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline to Week 52 of Self-assessment of VVA Symptom Dyspareunia

The severity of dyspareunia was evaluated by a questionnaire. The severity of dyspareunia recorded as none, mild, moderate or severe was analyzed using the score values of 0, 1, 2 or 3, respectively. Data obtained at Baseline and Week 52 as well as the change from Baseline to Week 52 are presented. (NCT01256671)
Timeframe: Baseline and Week 52

Interventionunits on a scale (Mean)
Baseline: Subgroup MSWeek 52: Subgroup MSChange from Baseline: Subgroup MSBaseline: Subgroup MBS/MSWeek 52: Subgroup MBS/MSChange from Baseline: Subgroup MBS/MS
0.50% DHEA2.530.85-1.682.570.87-1.69

Change From Baseline to Week 52 of Self-assessment of VVA Symptom Irritation/Itching

The severity of irritation/itching was evaluated by a questionnaire. The severity of irritation/itching recorded as none, mild, moderate or severe was analyzed using the score values of 0, 1, 2 or 3, respectively. Data obtained at Baseline and Week 52 as well as the change from Baseline to Week 52 are presented. (NCT01256671)
Timeframe: Baseline and Week 52

Interventionunits on a scale (Mean)
Baseline: Subgroup MSWeek 52: Subgroup MSChange from Baseline: Subgroup MSBaseline: Subgroup MBS/MSWeek 52: Subgroup MBS/MSChange from Baseline: Subgroup MBS/MS
0.50% DHEA2.100.60-1.502.130.74-1.39

Change From Baseline to Week 52 of Self-assessment of VVA Symptom Vaginal Dryness

The severity of vaginal dryness was evaluated by a questionnaire. The severity of vaginal dryness recorded as none, mild, moderate or severe was analyzed using the score values of 0, 1, 2 or 3, respectively. Data obtained at Baseline and Week 52 as well as the change from Baseline to Week 52 are presented. (NCT01256671)
Timeframe: Baseline and Week 52

Interventionunits on a scale (Mean)
Baseline: Subgroup MSWeek 52: Subgroup MSChange from Baseline: Subgroup MSBaseline: Subgroup MBS/MSWeek 52: Subgroup MBS/MSChange from Baseline: Subgroup MBS/MS
0.50% DHEA2.220.59-1.632.190.67-1.52

Change From Baseline to Week 52 of Vaginal Cell Maturation (Percentage of Parabasal Cells).

The percentage of parabasal cells was determined from the vaginal smears collected during the study. A 100-cell count was performed by a central laboratory to classify cells as parabasal (P) (including basal), intermediate (I), and superficial (S) squamous cell types. Data obtained at Baseline and Week 52 as well as the change from Baseline to Week 52 are presented. (NCT01256671)
Timeframe: Baseline and Week 52

Interventionpercentage of parabasal cells (Mean)
Baseline: Subgroup ALLWeek 52: Subgroup ALLChange from Baseline: Subgroup ALLBaseline: Subgroup VVAWeek 52: Subgroup VVAChange from Baseline: Subgroup VVA
0.50% DHEA55.4912.81-42.6763.9514.80-49.14

Change From Baseline to Week 52 of Vaginal Cell Maturation (Percentage of Superficial Cells).

The percentage of superficial cells was determined from the vaginal smears collected during the study. A 100-cell count was performed by a central laboratory to classify cells as parabasal (P) (including basal), intermediate (I), and superficial (S) squamous cell types. Data obtained at Baseline and Week 52 as well as the change from Baseline to Week 52 are presented. (NCT01256671)
Timeframe: Baseline and Week 52

Interventionpercentage of superficial cells (Mean)
Baseline: Subgroup ALLWeek 52: Subgroup ALLChange from Baseline: Subgroup ALLBaseline: Subgroup VVAWeek 52: Subgroup VVAChange from Baseline: Subgroup VVA
0.50% DHEA2.029.427.410.968.817.85

Change From Baseline to Week 52 of Vaginal pH.

A pH strip fixed on an Ayre spatula (or equivalent) was applied directly to the lateral wall of the vagina. The change in color of the pH indicator strip was compared to the color chart for pH evaluation. The corresponding pH value (with one decimal) was recorded. Data obtained at Baseline and Week 52 as well as the change from Baseline to Week 52 are presented. (NCT01256671)
Timeframe: Baseline and Week 52

InterventionpH (Mean)
Baseline: Subgroup ALLWeek 52: Subgroup ALLChange from Baseline: Subgroup ALLBaseline: Subgroup VVAWeek 52: Subgroup VVAChange from Baseline: Subgroup VVA
0.50% DHEA6.235.09-1.146.405.13-1.27

Long-term Safety of Intravaginal Prasterone (DHEA): Endometrium

The long-term safety of intravaginal prasterone has been evaluated on different parameters including the endometrium. For this purpose, endometrial biopsies were performed at screening and at the end of the study (52 weeks) or at discontinuation visit for women who were exposed to intravaginal DHEA (prasterone) for at least 12 weeks. At screening, the endometrium had to be atrophic/inactive for women to be enrolled in the study. Only the end-of-study data are presented. (NCT01256671)
Timeframe: Baseline and Week 52 (or discontinuation)

InterventionParticipants (Count of Participants)
Endometrium: Atrophic/InactiveEndometrium: No/Insufficient Tissue for Diagnosis
0.50% DHEA42136

Long-term Safety of Intravaginal Prasterone (DHEA): Serum Steroid Levels

The long-term safety of intravaginal prasterone has been evaluated on different parameters including the serum levels of DHEA and its metabolites. For this purpose, blood samples were collected at Baseline and different post-Baseline timepoints for the determination of serum steroid levels by a central laboratory using validated liquid chromatography tandem mass spectrometry (LC-MS/MS) methods. The serum levels of dehydroepiandrosterone (DHEA), estradiol (E2) and testosterone (TESTO) obtained at Baseline and Week 52 as well as the change from Baseline to Week 52 are presented. (NCT01256671)
Timeframe: Baseline and Week 52

Interventionpg/mL (Mean)
DHEA: BaselineDHEA: Week 52DHEA: Change from BaselineE2: BaselineE2: Week 52E2: Change from BaselineTESTO: BaselineTESTO: Week 52TESTO: Change from Baseline
0.50% DHEA2071.612997.25925.656.054.46-1.59161.28189.4428.17

Reviews

20 reviews available for dehydroepiandrosterone and Sex Disorders

ArticleYear
Efficacy of interventions to manage sexual dysfunction in women with cancer: a systematic review.
    Menopause (New York, N.Y.), 2022, 05-01, Volume: 29, Issue:5

    Topics: Cancer Survivors; Dehydroepiandrosterone; Dyspareunia; Female; Humans; Male; Neoplasms; Randomized C

2022
Sexual Dysfunctions in Women: Are Androgens at Fault?
    Endocrinology and metabolism clinics of North America, 2021, Volume: 50, Issue:1

    Topics: Androgens; Dehydroepiandrosterone; Female; Humans; Libido; Sexual Dysfunction, Physiological; Sexual

2021
Efficacy of intravaginal dehydroepiandrosterone (DHEA) for symptomatic women in the peri- or postmenopausal phase.
    Maturitas, 2018, Volume: 116

    Topics: Administration, Intravaginal; Dehydroepiandrosterone; Female; Humans; Perimenopause; Postmenopause;

2018
Androgen use for low sexual desire in midlife women.
    Menopause (New York, N.Y.), 2013, Volume: 20, Issue:7

    Topics: Androgens; Dehydroepiandrosterone; Female; Humans; Menopause; Middle Aged; Sex Hormone-Binding Globu

2013
Androgen therapy in women: for whom and when.
    Archives of gynecology and obstetrics, 2013, Volume: 288, Issue:4

    Topics: Aging; Androgens; Dehydroepiandrosterone; Female; Hormone Replacement Therapy; Humans; Hypogonadism;

2013
Androgens and Female Sexual Function and Dysfunction--Findings From the Fourth International Consultation of Sexual Medicine.
    The journal of sexual medicine, 2016, Volume: 13, Issue:2

    Topics: Adult; Androgens; Consensus Development Conferences as Topic; Dehydroepiandrosterone; Female; Hormon

2016
Future Targets for Female Sexual Dysfunction.
    The journal of sexual medicine, 2016, Volume: 13, Issue:8

    Topics: Alprostadil; Anxiety; Aphrodisiacs; Apomorphine; Consensus; Dehydroepiandrosterone; Dopamine; Dopami

2016
The effects of dehydroepiandrosterone on sexual function: a systematic review.
    Climacteric : the journal of the International Menopause Society, 2017, Volume: 20, Issue:2

    Topics: Dehydroepiandrosterone; Female; Humans; Libido; Middle Aged; Postmenopause; Quality of Life; Sexual

2017
DHEA for postmenopausal women: a review of the evidence.
    Maturitas, 2010, Volume: 66, Issue:2

    Topics: Carbohydrate Metabolism; Dehydroepiandrosterone; Female; Humans; Lipid Metabolism; Postmenopause; Se

2010
Management of vulvovaginal atrophy-related sexual dysfunction in postmenopausal women: an up-to-date review.
    Menopause (New York, N.Y.), 2012, Volume: 19, Issue:1

    Topics: Administration, Intravaginal; Adult; Aged; Aged, 80 and over; Atrophy; Breast Neoplasms; Complementa

2012
Hormonal causes of male sexual dysfunctions and their management (hyperprolactinemia, thyroid disorders, GH disorders, and DHEA).
    The journal of sexual medicine, 2013, Volume: 10, Issue:3

    Topics: Acromegaly; Adrenal Insufficiency; Dehydroepiandrosterone; Gonadotropins; Hormone Replacement Therap

2013
[Local estrogen therapy--clinical implications--2012 update].
    Ginekologia polska, 2012, Volume: 83, Issue:10

    Topics: Dehydroepiandrosterone; Estrogen Replacement Therapy; Estrogens; Female; Humans; Poland; Postmenopau

2012
[DHEA: desire and resistance].
    Gynecologie, obstetrique & fertilite, 2002, Volume: 30, Issue:12

    Topics: Aged; Aging; Breast Neoplasms; Dehydroepiandrosterone; Erectile Dysfunction; Female; Humans; Libido;

2002
Androgen therapy with dehydroepiandrosterone.
    World journal of urology, 2003, Volume: 21, Issue:5

    Topics: Adjuvants, Immunologic; Adrenal Insufficiency; Aged; Aging; Cardiovascular Diseases; Cognition; Dehy

2003
The role of androgens in hormone replacement therapy.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:11

    Topics: Adult; Age Factors; Aged; Androgens; Breast Neoplasms; Cardiovascular System; Dehydroepiandrosterone

2005
Clinical practice. Sexual desire and arousal disorders in women.
    The New England journal of medicine, 2006, Apr-06, Volume: 354, Issue:14

    Topics: Combined Modality Therapy; Dehydroepiandrosterone; Estrogens; Female; Humans; Middle Aged; Practice

2006
Clinical evaluation of women presenting with low libido and determination of whether androgen therapy might be appropriate.
    Seminars in reproductive medicine, 2006, Volume: 24, Issue:2

    Topics: Androgens; Dehydroepiandrosterone; Female; Humans; Libido; Norpregnenes; Sexual Dysfunction, Physiol

2006
Dehydroepiandrosterone therapy as female androgen replacement.
    Seminars in reproductive medicine, 2006, Volume: 24, Issue:2

    Topics: Adrenal Insufficiency; Aging; Androgens; Dehydroepiandrosterone; Female; Hormone Replacement Therapy

2006
Female androgen insufficiency.
    Obstetrics and gynecology clinics of North America, 2006, Volume: 33, Issue:4

    Topics: Adrenal Glands; Aging; Algorithms; Androgens; Dehydroepiandrosterone; Female; Humans; Libido; Ovarie

2006
[Significance of dehydroepiandrosterone and dehydroepiandrosterone sulfate in different diseases].
    Orvosi hetilap, 2007, Apr-08, Volume: 148, Issue:14

    Topics: Androgens; Cardiovascular Diseases; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diabetes

2007

Trials

3 trials available for dehydroepiandrosterone and Sex Disorders

ArticleYear
Restoring testosterone levels by adding dehydroepiandrosterone to a drospirenone containing combined oral contraceptive: II. Clinical effects.
    Contraception, 2015, Volume: 91, Issue:2

    Topics: Acne Vulgaris; Adolescent; Adult; Androgen Antagonists; Androstenes; Belgium; Contraceptives, Oral,

2015
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Effect of intravaginal dehydroepiandrosterone (DHEA) on the female sexual function in postmenopausal women: ERC-230 open-label study.
    Hormone molecular biology and clinical investigation, 2016, Volume: 25, Issue:3

    Topics: Administration, Intravaginal; Adult; Aged; Dehydroepiandrosterone; Double-Blind Method; Female; Huma

2016
Androgens and sexual function: a placebo-controlled, randomized, double-blind study of testosterone vs. dehydroepiandrosterone in men with sexual dysfunction and androgen deficiency.
    The aging male : the official journal of the International Society for the Study of the Aging Male, 2009, Volume: 12, Issue:4

    Topics: Aged; Androgens; Dehydroepiandrosterone; Double-Blind Method; Humans; Male; Middle Aged; Outcome Ass

2009

Other Studies

16 other studies available for dehydroepiandrosterone and Sex Disorders

ArticleYear
Dehydroepiandrosterone and cortisol as markers of HPA axis dysregulation in women with low sexual desire.
    Psychoneuroendocrinology, 2019, Volume: 104

    Topics: Adult; Biomarkers; Circadian Rhythm; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hypotha

2019
Localization of the androgen-synthesizing enzymes, androgen receptor, and sex steroids in the vagina: possible implications for the treatment of postmenopausal sexual dysfunction.
    The journal of sexual medicine, 2014, Volume: 11, Issue:8

    Topics: 17-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgens; Animals; Dehydro

2014
Intracrinology in action: importance of extragonadal sex steroid biosynthesis and inactivation in peripheral tissues in both women and men.
    The Journal of steroid biochemistry and molecular biology, 2015, Volume: 145

    Topics: Androgens; Atrophic Vaginitis; Clinical Trials as Topic; Dehydroepiandrosterone; Endocrinology; Estr

2015
DHEA replacement for postmenopausal women: placebo or panacea?
    Climacteric : the journal of the International Menopause Society, 2015, Volume: 18, Issue:4

    Topics: Administration, Intravaginal; Administration, Oral; Aged; Aging; Cognition Disorders; Dehydroepiandr

2015
Methodology and challenges to recruitment to a randomized, double-blind, placebo-controlled trial of oral DHEA in postmenopausal women.
    Journal of women's health (2002), 2008, Volume: 17, Issue:10

    Topics: Aged; Australia; Dehydroepiandrosterone; Double-Blind Method; Female; Health Knowledge, Attitudes, P

2008
Summary of the recommendations on sexual dysfunctions in women.
    The journal of sexual medicine, 2010, Volume: 7, Issue:1 Pt 2

    Topics: Adjuvants, Immunologic; Dehydroepiandrosterone; Diagnostic and Statistical Manual of Mental Disorder

2010
Identifying and treating sexual dysfunction in postmenopausal women: the role of estrogen.
    Journal of women's health (2002), 2011, Volume: 20, Issue:10

    Topics: Administration, Intravaginal; Aged; Breast Neoplasms; Dehydroepiandrosterone; Dosage Forms; Endometr

2011
Effects of ovariectomy and dehydroepiandrosterone (DHEA) on vaginal wall thickness and innervation.
    The journal of sexual medicine, 2012, Volume: 9, Issue:10

    Topics: Administration, Intravaginal; Animals; Dehydroepiandrosterone; Female; Mucous Membrane; Ovariectomy;

2012
Female sexual dysfunction in hypopituitarism.
    Lancet (London, England), 2007, Sep-01, Volume: 370, Issue:9589

    Topics: Dehydroepiandrosterone; Female; Humans; Hypopituitarism; Libido; Postmenopause; Sexual Dysfunction,

2007
[Non-virilizing hormonal therapy in women with secondary disorders of sexual responsiveness].
    Wiener klinische Wochenschrift, 1983, Jun-24, Volume: 95, Issue:13

    Topics: Adult; Clomiphene; Contraceptives, Oral, Combined; Dehydroepiandrosterone; Drug Combinations; Estrad

1983
Hormone levels in methadone-treated drug addicts.
    Drug and alcohol dependence, 1981, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradio

1981
Human 3 beta-hydroxysteroid dehydrogenase: genes and phenotypes.
    Journal of molecular endocrinology, 1996, Volume: 17, Issue:1

    Topics: 3-Hydroxysteroid Dehydrogenases; Dehydroepiandrosterone; Hirsutism; Humans; Mutation; Phenotype; Pol

1996
Reproductive endocrine disorders in women with partial seizures of temporal lobe origin.
    Archives of neurology, 1986, Volume: 43, Issue:4

    Topics: Adult; Dehydroepiandrosterone; Endocrine System Diseases; Epilepsy, Temporal Lobe; Estradiol; Female

1986
The effect of long-term administration of digoxin on plasma androgens and sexual dysfunction.
    Journal of sex & marital therapy, 1987,Spring, Volume: 13, Issue:1

    Topics: Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Digoxin; Erectile Dysfunction; Humans; Li

1987
Sex hormone changes in chronic liver disease: a matched study of alcoholic versus non-alcoholic liver disease.
    The Quarterly journal of medicine, 1987, Volume: 63, Issue:240

    Topics: Adult; Aged; Androstenedione; Dehydroepiandrosterone; Estradiol; Gonadal Steroid Hormones; Humans; L

1987
[Sexual changes in the adult male connected with hyperproduction of dehydroepiandrosterone at the adrenal gland level].
    Minerva medica, 1973, Mar-10, Volume: 64, Issue:13

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adult; Dehydroepiandrosterone; Female; Gyn

1973