Page last updated: 2024-11-07

dehydroepiandrosterone and Sarcopenia

dehydroepiandrosterone has been researched along with Sarcopenia in 4 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Sarcopenia: Progressive decline in muscle mass due to aging which results in decreased functional capacity of muscles.

Research Excerpts

ExcerptRelevanceReference
"Postmenopausal women with sarcopenia were more likely to have lower DHEA levels and higher follistatin levels, and postmenopausal women with osteoporosis were more likely to have lower oxytocin levels."8.02Serum concentrations of oxytocin, DHEA and follistatin are associated with osteoporosis or sarcopenia in community-dwelling postmenopausal women. ( Chen, M; Cheng, Q; Du, Y; Jiang, X; Li, H; Shi, H; Tang, W; Wu, X; Xu, C; Zhang, X, 2021)
"Postmenopausal women with sarcopenia were more likely to have lower DHEA levels and higher follistatin levels, and postmenopausal women with osteoporosis were more likely to have lower oxytocin levels."4.02Serum concentrations of oxytocin, DHEA and follistatin are associated with osteoporosis or sarcopenia in community-dwelling postmenopausal women. ( Chen, M; Cheng, Q; Du, Y; Jiang, X; Li, H; Shi, H; Tang, W; Wu, X; Xu, C; Zhang, X, 2021)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Du, Y1
Xu, C1
Shi, H1
Jiang, X1
Tang, W1
Wu, X1
Chen, M1
Li, H1
Zhang, X1
Cheng, Q1
Huang, K1
Cai, HL1
Bao, JP1
Wu, LD1
Fragala, MS1
Dam, TT1
Barber, V1
Judge, JO1
Studenski, SA1
Cawthon, PM1
McLean, RR1
Harris, TB1
Ferrucci, L1
Guralnik, JM1
Kiel, DP1
Kritchevsky, SB1
Shardell, MD1
Vassileva, MT1
Kenny, AM1
Vitale, G1
Cesari, M1
Mari, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective Trial to Evaluate the Utility of Focused Frailty Interventions on Patients With Advanced Heart Failure[NCT03574662]1 participants (Actual)Interventional2018-05-04Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for dehydroepiandrosterone and Sarcopenia

ArticleYear
Dehydroepiandrosterone and age-related musculoskeletal diseases: Connections and therapeutic implications.
    Ageing research reviews, 2020, Volume: 62

    Topics: Aged; Aging; Dehydroepiandrosterone; Humans; Musculoskeletal Diseases; Osteoporosis; Sarcopenia

2020
Aging of the endocrine system and its potential impact on sarcopenia.
    European journal of internal medicine, 2016, Volume: 35

    Topics: Aged; Aging; Dehydroepiandrosterone; Endocrine System; Hormone Replacement Therapy; Humans; Muscle,

2016

Other Studies

2 other studies available for dehydroepiandrosterone and Sarcopenia

ArticleYear
Serum concentrations of oxytocin, DHEA and follistatin are associated with osteoporosis or sarcopenia in community-dwelling postmenopausal women.
    BMC geriatrics, 2021, 10-12, Volume: 21, Issue:1

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Dehydroepiandrosterone; Female; Follistatin; Human

2021
Strength and function response to clinical interventions of older women categorized by weakness and low lean mass using classifications from the Foundation for the National Institute of Health sarcopenia project.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2015, Volume: 70, Issue:2

    Topics: Absorptiometry, Photon; Adjuvants, Immunologic; Aged; Body Composition; Bone Density Conservation Ag

2015