Page last updated: 2024-11-07

dehydroepiandrosterone and Reperfusion Injury

dehydroepiandrosterone has been researched along with Reperfusion Injury in 12 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"This study evaluated the potential for dehydroepiandrosterone (DHEA) to protect skeletal muscle from reperfusion injury using intravital microscopic observations of isolated rat cremaster muscle flaps."7.69Dehydroepiandrosterone protects muscle flap microcirculatory hemodynamics from ischemia/reperfusion injury: an experimental in vivo study. ( Araneo, B; Barton, S; Lohman, R; Siemionow, M; Yowell, R, 1997)
"In dehydroepiandrosterone-treated animals, leukocytes exhibited lower levels of expression of adhesion molecules after the onset of ischemia, compared with the control groups."5.32Dehydroepiandrosterone protects the microcirculation of muscle flaps from ischemia-reperfusion injury by reducing the expression of adhesion molecules. ( Araneo, B; Ayhan, S; Norton, S; Siemionow, M; Tugay, C, 2003)
"This study evaluated the potential for dehydroepiandrosterone (DHEA) to protect skeletal muscle from reperfusion injury using intravital microscopic observations of isolated rat cremaster muscle flaps."3.69Dehydroepiandrosterone protects muscle flap microcirculatory hemodynamics from ischemia/reperfusion injury: an experimental in vivo study. ( Araneo, B; Barton, S; Lohman, R; Siemionow, M; Yowell, R, 1997)
"Testicular torsion is a urological emergency most commonly seen in adolescence, involving a decrease in blood flow in the testis resulting from torsion of the spermatic cord that can result in gonad injury or even loss if not treated in time."2.50Mechanisms of testicular torsion and potential protective agents. ( Kadihasanoglu, M; Karaguzel, E; Kutlu, O, 2014)
"In dehydroepiandrosterone-treated animals, leukocytes exhibited lower levels of expression of adhesion molecules after the onset of ischemia, compared with the control groups."1.32Dehydroepiandrosterone protects the microcirculation of muscle flaps from ischemia-reperfusion injury by reducing the expression of adhesion molecules. ( Araneo, B; Ayhan, S; Norton, S; Siemionow, M; Tugay, C, 2003)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's8 (66.67)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zaric, M1
Drakulic, D1
Stojanovic, IG1
Mitrovic, N1
Grkovic, I1
Martinovic, J1
Karaguzel, E1
Kadihasanoglu, M1
Kutlu, O1
Hosszu, A1
Antal, Z1
Lenart, L1
Hodrea, J1
Koszegi, S1
Balogh, DB1
Banki, NF1
Wagner, L1
Denes, A1
Hamar, P1
Degrell, P1
Vannay, A2
Szabo, AJ2
Fekete, A2
Langer, R1
Tóth, T1
Sziksz, E1
Vásárhelyi, B1
Losonczy, G1
Adori, C1
Gál, A1
Tulassay, T1
Szabó, A1
Ayhan, S1
Tugay, C1
Norton, S1
Araneo, B2
Siemionow, M2
Aragno, M2
Cutrin, JC1
Mastrocola, R1
Perrelli, MG1
Restivo, F1
Poli, G1
Danni, O2
Boccuzzi, G2
Yildirim, A1
Gumus, M1
Dalga, S1
Sahin, YN1
Akcay, F1
Aksoy, Y3
Yapanoglu, T3
Aksou, H1
Yildirim, AK1
Aksoy, H1
Ozbey, I2
Turhan, H1
Gursan, N2
Ziypak, T1
Calik, M1
Lohman, R1
Yowell, R1
Barton, S1
Parola, S1
Brignardello, E1
Mauro, A1
Tamagno, E1
Manti, R1

Reviews

1 review available for dehydroepiandrosterone and Reperfusion Injury

ArticleYear
Mechanisms of testicular torsion and potential protective agents.
    Nature reviews. Urology, 2014, Volume: 11, Issue:7

    Topics: Adjuvants, Immunologic; Anesthetics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants;

2014

Other Studies

11 other studies available for dehydroepiandrosterone and Reperfusion Injury

ArticleYear
Regional-specific effects of cerebral ischemia/reperfusion and dehydroepiandrosterone on synaptic NMDAR/PSD-95 complex in male Wistar rats.
    Brain research, 2018, 06-01, Volume: 1688

    Topics: Animals; Brain Ischemia; Dehydroepiandrosterone; Disks Large Homolog 4 Protein; Hippocampus; Male; N

2018
σ1-Receptor Agonism Protects against Renal Ischemia-Reperfusion Injury.
    Journal of the American Society of Nephrology : JASN, 2017, Volume: 28, Issue:1

    Topics: Acute Kidney Injury; Animals; Dehydroepiandrosterone; Fluvoxamine; Kidney; Male; Rats; Rats, Wistar;

2017
Dehydroepiandrosterone pretreatment alters the ischaemia/reperfusion-induced VEGF, IL-1 and IL-6 gene expression in acute renal failure.
    Kidney & blood pressure research, 2009, Volume: 32, Issue:3

    Topics: Acute Kidney Injury; Animals; Dehydroepiandrosterone; Gene Expression Regulation; Intercellular Sign

2009
Dehydroepiandrosterone protects the microcirculation of muscle flaps from ischemia-reperfusion injury by reducing the expression of adhesion molecules.
    Plastic and reconstructive surgery, 2003, Volume: 111, Issue:7

    Topics: Animals; Blood Flow Velocity; Cell Adhesion Molecules; Dehydroepiandrosterone; Flow Cytometry; Hyalu

2003
Oxidative stress and kidney dysfunction due to ischemia/reperfusion in rat: attenuation by dehydroepiandrosterone.
    Kidney international, 2003, Volume: 64, Issue:3

    Topics: Animals; Antioxidants; Dehydroepiandrosterone; Immunohistochemistry; Kidney; Male; Oxidative Stress;

2003
Dehydroepiandrosterone improves hepatic antioxidant systems after renal ischemia-reperfusion injury in rabbits.
    Annals of clinical and laboratory science, 2003,Fall, Volume: 33, Issue:4

    Topics: Animals; Antioxidants; Catalase; Dehydroepiandrosterone; Glutathione; Glutathione Peroxidase; Liver;

2003
The effect of dehydroepiandrosterone on renal ischemia-reperfusion-induced oxidative stress in rabbits.
    Urological research, 2004, Volume: 32, Issue:2

    Topics: Animals; Antioxidants; Catalase; Dehydroepiandrosterone; Glutathione Peroxidase; Lipid Peroxidation;

2004
Dehydroepiandrosterone treatment attenuates reperfusion injury after testicular torsion and detorsion in rats.
    Journal of pediatric surgery, 2007, Volume: 42, Issue:10

    Topics: Animals; Catalase; Dehydroepiandrosterone; Drug Evaluation, Preclinical; Free Radical Scavengers; Is

2007
Antiapoptotic effects of dehydroepiandrosterone on testicular torsion/detorsion in rats.
    Andrologia, 2008, Volume: 40, Issue:1

    Topics: Animals; Apoptosis; Dehydroepiandrosterone; Germ Cells; Male; Rats; Rats, Sprague-Dawley; Reperfusio

2008
Dehydroepiandrosterone protects muscle flap microcirculatory hemodynamics from ischemia/reperfusion injury: an experimental in vivo study.
    The Journal of trauma, 1997, Volume: 42, Issue:1

    Topics: Animals; Antioxidants; Dehydroepiandrosterone; Hemodynamics; Male; Microcirculation; Microscopy, Ele

1997
Dehydroepiandrosterone prevents oxidative injury induced by transient ischemia/reperfusion in the brain of diabetic rats.
    Diabetes, 2000, Volume: 49, Issue:11

    Topics: Animals; Antioxidants; Brain Ischemia; Cell Membrane; Dehydroepiandrosterone; Diabetes Mellitus, Exp

2000