dehydroepiandrosterone has been researched along with Recrudescence in 14 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The goal of this pilot study was to evaluate the effect of dehydroepiandrosterone (DHEA) on depressed mood and fatigue in HIV+ men and women, unselected for baseline DHEA level." | 5.09 | DHEA treatment for HIV+ patients: effects on mood, androgenic and anabolic parameters. ( Ferrando, SJ; Rabkin, JG; Rabkin, R; Wagner, GJ, 2000) |
| "Breast cancer is the most common malignancy in women with high mortality." | 2.72 | Breast Cancer: Targeting of Steroid Hormones in Cancerogenesis and Diagnostics. ( Kostecká, Z; Očenáš, P; Salayová, A; Valko-Rokytovská, M, 2021) |
| "PTSD was related to shorter time to lapse (hazard ratio [HR] = 1." | 1.39 | Predictors of lapse in first week of smoking abstinence in PTSD and non-PTSD smokers. ( Beckham, JC; Calhoun, PS; Dedert, EA; Dennis, MF; Wilson, SM, 2013) |
| "Depressive symptoms, smoking withdrawal symptoms, and plasma steroid levels were measured before and after 8 days of verified smoking abstinence." | 1.33 | A decrease in the plasma DHEA to cortisol ratio during smoking abstinence may predict relapse: a preliminary study. ( Anderson, GM; Krishnan-Sarin, S; Paliwal, P; Rasmusson, AM; Wu, R, 2006) |
| "Recurrent prostate cancer specimens from 22 men whose prostate cancer recurred locally during androgen deprivation therapy and benign prostate specimens from 48 men who had received no prior treatment were studied." | 1.32 | The androgen axis in recurrent prostate cancer. ( Ford, OH; French, FS; Gregory, CW; Kim, D; Mohler, JL; Petrusz, P; Weaver, CM; Wilson, EM, 2004) |
| "The ability of human breast carcinomas to convert pregnenolone to progesterone and dehydroepiandrosterone to delta 4-androstene-3,17-dione (delta 4) was investigated as a potential aid for prognosis, and the following observations were recorded." | 1.26 | Hormone synthesis by primary breast carcinomas and prognosis in human breast cancer. ( Deshpande, N; Di Martino, L; Mitchell, I; Tarquini, A, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Valko-Rokytovská, M | 1 |
| Očenáš, P | 1 |
| Salayová, A | 1 |
| Kostecká, Z | 1 |
| El Asmar, N | 1 |
| Rajpal, A | 1 |
| Selman, WR | 1 |
| Arafah, BM | 1 |
| Ohana, D | 1 |
| Maayan, R | 1 |
| Delayahu, Y | 1 |
| Roska, P | 1 |
| Ponizovsky, AM | 1 |
| Weizman, A | 1 |
| Yadid, G | 1 |
| Yechiam, E | 1 |
| Orefice, N | 1 |
| Carotenuto, A | 1 |
| Mangone, G | 1 |
| Bues, B | 1 |
| Rehm, R | 1 |
| Cerillo, I | 1 |
| Saccà, F | 1 |
| Calignano, A | 1 |
| Orefice, G | 1 |
| Beckham, JC | 1 |
| Calhoun, PS | 1 |
| Dennis, MF | 1 |
| Wilson, SM | 1 |
| Dedert, EA | 1 |
| Mohler, JL | 1 |
| Gregory, CW | 1 |
| Ford, OH | 1 |
| Kim, D | 1 |
| Weaver, CM | 1 |
| Petrusz, P | 1 |
| Wilson, EM | 1 |
| French, FS | 1 |
| Poór, V | 1 |
| Juricskay, S | 1 |
| Gáti, A | 1 |
| Osváth, P | 1 |
| Tényi, T | 1 |
| Rasmusson, AM | 1 |
| Wu, R | 1 |
| Paliwal, P | 1 |
| Anderson, GM | 1 |
| Krishnan-Sarin, S | 1 |
| Di Martino, L | 1 |
| Tarquini, A | 1 |
| Mitchell, I | 1 |
| Deshpande, N | 1 |
| Matsunaga, H | 1 |
| Sarai, M | 1 |
| Littman, AB | 1 |
| Fava, M | 1 |
| Halperin, P | 1 |
| Lamon-Fava, S | 1 |
| Drews, FR | 1 |
| Oleshansky, MA | 1 |
| Bielenda, CC | 1 |
| MacLaughlin, RA | 1 |
| Rabkin, JG | 1 |
| Ferrando, SJ | 1 |
| Wagner, GJ | 1 |
| Rabkin, R | 1 |
| Geller, J | 1 |
| Albert, J | 1 |
| Yen, SS | 1 |
| Louard, RJ | 1 |
| Gelfand, RA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Male Hormonal Contraceptive Regimens on Prostate Tissue In Normal Men[NCT00490555] | Phase 2/Phase 3 | 32 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00490555)
Timeframe: 10 weeks
| Intervention | ng/mL (Median) |
|---|---|
| 1) Placebo | 0.9 |
| 2) Testosterone Gel | 0.9 |
| 3) T Gel +Dutasteride | 1.8 |
| 4) T Gel+ DMPA | 0.7 |
(NCT00490555)
Timeframe: 10 weeks
| Intervention | ng/mL (Median) |
|---|---|
| 1) Placebo | 4.3 |
| 2) Testosterone Gel | 3.5 |
| 3) T Gel +Dutasteride | 3.8 |
| 4) T Gel+ DMPA | 3.2 |
(NCT00490555)
Timeframe: 10 weeks
| Intervention | ng/mL (Median) |
|---|---|
| 1) Placebo | 0.5 |
| 2) Testosterone Gel | 1.8 |
| 3) T Gel +Dutasteride | 0.5 |
| 4) T Gel+ DMPA | 0.6 |
PSA level week 10 end of treatment (NCT00490555)
Timeframe: 10 weeks
| Intervention | ng/mL (Median) |
|---|---|
| 1) Placebo | 0.8 |
| 2) Testosterone Gel | 0.9 |
| 3) T Gel +Dutasteride | 0.7 |
| 4) T Gel+ DMPA | 0.4 |
(NCT00490555)
Timeframe: 10 weeks
| Intervention | ng/mL (Median) |
|---|---|
| 1) Placebo | 4.0 |
| 2) Testosterone Gel | 4.4 |
| 3) T Gel +Dutasteride | 7.0 |
| 4) T Gel+ DMPA | 1.8 |
1 review available for dehydroepiandrosterone and Recrudescence
| Article | Year |
|---|---|
Breast Cancer: Targeting of Steroid Hormones in Cancerogenesis and Diagnostics.
Topics: Androstenedione; Biomarkers, Tumor; Breast Neoplasms; Dehydroepiandrosterone; Dihydrotestosterone; E | 2021 |
1 trial available for dehydroepiandrosterone and Recrudescence
| Article | Year |
|---|---|
DHEA treatment for HIV+ patients: effects on mood, androgenic and anabolic parameters.
Topics: Adult; Affect; Androgens; Body Composition; CD4 Lymphocyte Count; Dehydroepiandrosterone; Dehydroepi | 2000 |
12 other studies available for dehydroepiandrosterone and Recrudescence
| Article | Year |
|---|---|
The Value of Perioperative Levels of ACTH, DHEA, and DHEA-S and Tumor Size in Predicting Recurrence of Cushing Disease.
Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Deh | 2018 |
Effect of dehydroepiandrosterone add-on therapy on mood, decision making and subsequent relapse of polydrug users.
Topics: Adjuvants, Immunologic; Adult; Affect; Decision Making; Dehydroepiandrosterone; Double-Blind Method; | 2016 |
Assessment of neuroactive steroids in cerebrospinal fluid comparing acute relapse and stable disease in relapsing-remitting multiple sclerosis.
Topics: Adult; Biomarkers; Brain; Dehydroepiandrosterone; Female; Humans; Male; Middle Aged; Multiple Sclero | 2016 |
Predictors of lapse in first week of smoking abstinence in PTSD and non-PTSD smokers.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfat | 2013 |
The androgen axis in recurrent prostate cancer.
Topics: Aged; Aged, 80 and over; Androgens; Androstenedione; Antibodies, Monoclonal; Cell Nucleus; Dehydroep | 2004 |
Urinary steroid metabolites and 11beta-hydroxysteroid dehydrogenase activity in patients with unipolar recurrent major depression.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Cortex Hormones; Adult; Arousal; Corticosterone; Dehy | 2004 |
A decrease in the plasma DHEA to cortisol ratio during smoking abstinence may predict relapse: a preliminary study.
Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depression; Female; Humans; Hydrocort | 2006 |
Hormone synthesis by primary breast carcinomas and prognosis in human breast cancer.
Topics: Androgens; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Neoplasm Stagi | 1980 |
Elevated serum LH and androgens in affective disorder related to the menstrual cycle: with reference to polycystic ovary syndrome.
Topics: Adolescent; Adult; Androgens; Androstenedione; Bipolar Disorder; Dehydroepiandrosterone; Dehydroepia | 1993 |
Physiologic benefits of a stress reduction program for healthy middle-aged Army officers.
Topics: Adult; Arousal; Behavior Therapy; Coronary Disease; Dehydroepiandrosterone; Dehydroepiandrosterone S | 1993 |
Treatment of advanced cancer of prostate with megestrol acetate.
Topics: Acid Phosphatase; Bone and Bones; Dehydroepiandrosterone; Humans; Male; Megestrol; Prostatic Neoplas | 1978 |
Recurrent Cushing's disease with low adrenal androgen production.
Topics: 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androgens; Cushing Syndrome; De | 1991 |