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dehydroepiandrosterone and Puberty, Precocious

dehydroepiandrosterone has been researched along with Puberty, Precocious in 85 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Puberty, Precocious: Development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations below the mean age at onset of PUBERTY in the population. This early maturation of the hypothalamic-pituitary-gonadal axis results in sexual precocity, elevated serum levels of GONADOTROPINS and GONADAL STEROID HORMONES such as ESTRADIOL and TESTOSTERONE.

Research Excerpts

ExcerptRelevanceReference
"6 years, height, weight, fat mass, fasting insulin concentration, insulin resistance (by HOMA-R; see text), and leptin and IGF-I levels were determined to test whether they explain the variance of the levels of dehydroepiandrosterone (DHEA) and its sulfate (DHEAS), of androstenedione, and of cortisol before and during 42 months of therapy with growth hormone."9.10Increased adrenal androgen levels in patients with Prader-Willi syndrome are associated with insulin, IGF-I, and leptin, but not with measures of obesity. ( Blum, W; Eiholzer, U; Gasser, T; Girard, J; L'Allemand, D; Rousson, V; Torresani, T, 2002)
"6 years, height, weight, fat mass, fasting insulin concentration, insulin resistance (by HOMA-R; see text), and leptin and IGF-I levels were determined to test whether they explain the variance of the levels of dehydroepiandrosterone (DHEA) and its sulfate (DHEAS), of androstenedione, and of cortisol before and during 42 months of therapy with growth hormone."5.10Increased adrenal androgen levels in patients with Prader-Willi syndrome are associated with insulin, IGF-I, and leptin, but not with measures of obesity. ( Blum, W; Eiholzer, U; Gasser, T; Girard, J; L'Allemand, D; Rousson, V; Torresani, T, 2002)
" The frequency of obesity and the correlation between dehydroepiandrosterone sulphate levels and body mass index suggest that body weight is involved in the onset of adrenarche."3.72Premature pubarche as an indicator of how body weight influences the onset of adrenarche. ( Brauner, R; Charkaluk, ML; Trivin, C, 2004)
"Serum sulphates of 5-androstene-3 beta, 17 beta-diol (5-ADIOL-S), 5 alpha-androstane-3 alpha,17 beta-diol (3 alpha-DIOL-S) and dehydroepiandrosterone (DHEA-S), as well as unconjugated androstenedione (AD), testosterone (T) and 17 alpha-hydroxyprogesterone (17OHP), sex hormone binding globulin (SHBG) and the free androgen index (FAI) were measured by specific radioimmunoassay in girls with premature adrenarche (n = 9-16), and in hirsute women with (1) late onset 21 hydroxylase deficiency (n = 14), (2) polycystic ovarian disease (n = 28) and (3) idiopathic hirsutism (n = 74)."3.67Serum C-19 steroid sulphates in females with clinical hyperandrogenism. ( Callan, A; Connelly, JF; Davies, HE; Funder, JW; Montalo, J; Yong, AB, 1989)
" The transectional or longitudinal study of the plasma levels of dehydroepiandrosterone, its sulfate (DHAS), delta 4-androstenedione, testosterone, and 170H-progesterone in 121 children with a variety of clinical disorders in which adrenarchal and gonadal maturations are dissociated (precocious adrenarche, precocious or delayed puberty, adrenal insufficiency, gonadal dysgenesis, hypogonadotropism hypogonadotrophic) is presented."3.66[Does adrenarche really play a determining role in pubertal development? A study of the dissociations between adrenarche and gonadarche. The failure of dehydroepiandrosterone sulfate treatment in delayed adrenarche]. ( David, M; de Peretti, E; Forest, MG; Sempe, M, 1982)
"Leptin is a metabolic signal that may be involved in signaling adequacy of energy metabolism for the onset of reproductive function."2.69Serum leptin levels in patients with progressive central precocious puberty. ( Blum, WF; Heger, S; Kiess, W; Partsch, CJ; Peter, M; Sippell, WG, 1999)
"We describe a female child with pituitary gigantism and precocious adrenarche."2.38A child with pituitary gigantism and precocious adrenarche: does GH and/or PRL advance the onset of adrenarche? ( Iwatani, N; Kodama, M; Seto, H, 1992)
" Chronic administration of long acting GnRH agonists (GnRHa), like continuous infusion of high doses of the native peptide, results in suppression of pituitary gonadotropin secretion."2.37Use of a potent, long acting agonist of gonadotropin-releasing hormone in the treatment of precocious puberty. ( Bode, HH; Boepple, PA; Crawford, JD; Crigler, JF; Crowley, WF; Mansfield, MJ; Rudlin, CR; Wierman, ME, 1986)
"Clinical virilization with or without hypercortisolism was found in all eight children, who were 5 years old or younger."2.37Virilizing adrenocortical tumors in childhood: eight cases and a review of the literature. ( Green, OC; Lee, PD; Winter, RJ, 1985)
"After surgery, the boy entered true precocious puberty."1.37Clinical and metabolic findings in a 6-year-old boy with a Leydig cell tumour. ( Hartmann, MF; Lignitz, S; Partsch, CJ; Pohlenz, J; Wudy, SA, 2011)
"Testicular tumors are very rare in boys, approximately 1."1.31[Precocious puberty caused by a testicular Leydig cell tumor]. ( Borbás, E; Minik, K; Réti, G; Ságodi, L; Sólyom, E, 2001)
"The occurrence of nonclassical congenital adrenal hyperplasia among children with precocious pubarche is still a matter of debate."1.28Adrenal steroidogenic defects in children with precocious pubarche. ( Borrelli, P; Cambiaso, P; Cappa, M; Danielli, E; del Balzo, P, 1992)
"central precocious puberty, indicating that they are controlled by independent mechanisms."1.28Lack of adrenarche in two children with precocious puberty secondary to hypothalamic hamartoma. ( Brauner, R; Rappaport, R, 1989)
"In 29 children with central precocious puberty, gonadarche was suppressed with LHRHa administration for 1-4 yr."1.27Adrenarche and skeletal maturation during luteinizing hormone releasing hormone analogue suppression of gonadarche. ( Beardsworth, DE; Bode, HH; Boepple, PA; Crawford, JD; Crigler, JF; Crowley, WF; Kushner, DC; Mansfield, MJ; Wierman, ME, 1986)
"Nineteen patients had idiopathic precocious puberty and 8 had organic lesions (hamartoma, hydrocephalus or suprasellar arachnoid cyst)."1.27Treatment of central precocious puberty with an LHRH agonist (Buserelin): effect on growth and bone maturation after three years of treatment. ( Brauner, R; Fontoura, M; Rappaport, R, 1987)
"True precocious puberty is frequently secondary to intrinsic central nervous system pathology, but is rare following external head trauma."1.27Precocious puberty following severe head trauma. ( Chernausek, SD; Shaul, PW; Towbin, RB, 1985)
"We treated five girls with idiopathic precocious puberty (ages two to eight) for eight weeks with daily subcutaneous injections of LHRHa."1.26Short-term treatment of idiopathic precocious puberty with a long-acting analogue of luteinizing hormone-releasing hormone. A preliminary report. ( Comite, F; Crowley, WF; Cutler, GB; Loriaux, DL; Rivier, J; Vale, WW, 1981)

Research

Studies (85)

TimeframeStudies, this research(%)All Research%
pre-199049 (57.65)18.7374
1990's20 (23.53)18.2507
2000's11 (12.94)29.6817
2010's5 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cao, B1
Gong, C1
Wu, D1
Liang, X1
Li, W1
Liu, M1
Su, C1
Qin, M1
Meng, X1
Wei, L1
Binder, G1
Schweizer, R1
Blumenstock, G1
Ferrand, N1
Idkowiak, J1
Elhassan, YS1
Mannion, P1
Smith, K2
Webster, R1
Saraff, V1
Barrett, TG1
Shaw, NJ1
Krone, N2
Dias, RP1
Kershaw, M1
Kirk, JM1
Högler, W1
Krone, RE1
O'Reilly, MW1
Arlt, W2
Delany, FM1
Byrne, ML1
Whittle, S1
Simmons, JG1
Olsson, C1
Mundy, LK1
Patton, GC1
Allen, NB1
Zheng, F1
Zhu, H2
Jiang, YJ2
Diaz, A1
Bhandari, S1
Sison, C1
Vogiatzi, M1
Belgorosky, A1
Baquedano, MS1
Guercio, G1
Rivarola, MA2
Noordam, C1
Dhir, V1
McNelis, JC1
Schlereth, F1
Hanley, NA1
Smeitink, JA1
Smeets, R1
Sweep, FC1
Claahsen-van der Grinten, HL1
Lignitz, S1
Partsch, CJ3
Wudy, SA1
Hartmann, MF1
Pohlenz, J1
L'Allemand, D1
Eiholzer, U1
Rousson, V1
Girard, J1
Blum, W1
Torresani, T1
Gasser, T1
NATOLI, A1
MAGLIOCCA, R1
BEAS, F1
ZURBUGG, RP1
LEIBOW, SG1
PATTON, RG1
GARDNER, LI2
ZURBRUGG, RP1
MORTIMER, JG1
RUDD, BT1
BUTT, WR1
Charkaluk, ML1
Trivin, C1
Brauner, R3
Mermejo, LM1
Elias, LL1
Marui, S1
Moreira, AC1
Mendonca, BB2
de Castro, M1
Chen, LQ1
Liang, L1
Zou, CC1
Fu, JF1
Zhao, ZY1
Lappalainen, S1
Utriainen, P1
Kuulasmaa, T1
Voutilainen, R1
Jääskeläinen, J1
Ojeda, SR1
Andrews, WW1
Advis, JP1
White, SS1
Petrus, M1
Dutau, G1
Rochiccioli, P1
Hughes, IA1
Rosenfield, RL2
Rich, BH1
Lucky, AW1
Forest, MG2
de Peretti, E1
David, M1
Sempe, M1
Vihko, R1
Apter, D1
Roger, M1
Chaussain, JL1
Evain, D1
Toublanc, JE1
Canlorbe, P1
Scholler, R1
Wohltmann, H1
Mathur, RS1
Williamson, HO1
Sklar, CA2
Kaplan, SL2
Grumbach, MM2
Comite, F1
Cutler, GB1
Rivier, J1
Vale, WW1
Loriaux, DL1
Crowley, WF4
Dumic, M1
Tajic, M1
Mardesic, D1
Kalafatic, Z1
Lazar, L2
Kauli, R2
Bruchis, C2
Nordenberg, J2
Galatzer, A2
Pertzelan, A2
Ibáñez, L4
Bonnin, MR1
Zampolli, M2
Prat, N1
Alia, PJ1
Navarro, MA1
Balducci, R3
Boscherini, B2
Mangiantini, A3
Morellini, M1
Toscano, V3
Finocchi, G1
Bianchi, P1
Guglielmi, R1
Garibaldi, LR2
Aceto, T2
Weber, C1
Sakkal-Alkaddour, H1
Zhang, L1
Yang, X1
Chang, YT1
Kappy, M1
Slover, RS1
Jorgensen, V1
Pang, S1
Potau, N3
Street, ME1
Carrascosa, A1
Heger, S1
Peter, M1
Blum, WF1
Kiess, W1
Sippell, WG2
Marcos, MV2
de Zegher, F1
Miller, WL1
Ságodi, L1
Borbás, E1
Réti, G1
Minik, K1
Sólyom, E1
Valls, C1
Rodriguez-Hierro, F1
de, ZF1
Sizonenko, PC4
Bartolozzi, G1
Bernini, G1
Cagnoli, L1
Bruni, V1
Buratti, R1
Paunier, L1
Carmignac, D1
Reiter, EO1
Fuldauer, VG1
Root, AW1
Drucker, WD1
Job, JC1
del Balzo, P1
Borrelli, P1
Cambiaso, P1
Danielli, E1
Cappa, M1
Iwatani, N1
Kodama, M1
Seto, H1
Cavallo, A1
Leite, MV1
Arnhold, IJ1
Estefan, V1
Nunes, C1
Nicolau, W1
Bloise, W1
Jabbar, M1
Pugliese, M1
Fort, P1
Recker, B1
Lifshitz, F1
Tanaka, T1
Hibi, I1
Kato, K1
Saito, S1
Shimizu, N1
Suwa, S1
Nakajima, H1
Riddick, LM1
Wang, ME1
Senne, AR1
Klimah, PE1
Clark, AT1
Levine, LS1
Oberfield, SE1
Pang, SY1
Oostdijk, W1
Hümmelink, R1
Odink, RJ1
Drop, SL1
Lorenzen, F1
van der Velde, EA1
Schultheiss, H1
Nishi, Y1
Rappaport, R3
Montalo, J1
Funder, JW1
Yong, AB1
Callan, A1
Davies, HE1
Connelly, JF1
Adamo, MV1
Cives, C1
Kaplowitz, PB1
Cockrell, JL1
Young, RB1
Wierman, ME2
Beardsworth, DE1
Crawford, JD3
Crigler, JF3
Mansfield, MJ3
Bode, HH2
Boepple, PA3
Kushner, DC1
Rudlin, CR2
Karol, KA1
Fontoura, M1
Granoff, AB2
Chasalow, FI2
Blethen, SL2
Tse, TF1
Shaul, PW1
Towbin, RB1
Chernausek, SD1
Lee, PD1
Winter, RJ1
Green, OC1
Conly, PW1
Sandberg, DH1
Cleveland, WW1
Gupta, D2
Zimprich, H1
Teller, WM1
Camacho, AM1
Migeon, CJ2
Saez, JM1
Bertrand, J1
Schindler, H1
Root, A1
Steinberger, E1
Steinberger, A1
Russ, D1
Somers, L1
Rosenfield, R1
Boon, DA1
Keenan, RE1
Salunwhite, WR1
Rager, K1
Huenges, R1
Bierich, JR1
Bayard, F1
Duval-Beaupere, G1
Blizzard, RM1
Ernould, HJ1
Thibaut, A1
Decamps, G1
Göbel, P1

Reviews

10 reviews available for dehydroepiandrosterone and Puberty, Precocious

ArticleYear
Adrenarche: postnatal adrenal zonation and hormonal and metabolic regulation.
    Hormone research, 2008, Volume: 70, Issue:5

    Topics: Adrenal Cortex; Adrenal Medulla; Adrenarche; Adult; Androgens; Cell Differentiation; Child; Child, P

2008
Recent advances in the endocrinology of puberty.
    Endocrine reviews, 1980,Summer, Volume: 1, Issue:3

    Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Hormones; Animals; Child; Child, Preschool; Dehydroepiand

1980
[Common and uncommon forms of female sexual precocity and their biological diagnosis].
    Annales de pediatrie, 1984, Volume: 31, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital;

1984
Endocrine laboratory findings in pubertal distrubances.
    Clinics in endocrinology and metabolism, 1975, Volume: 4, Issue:1

    Topics: Adolescent; Adrenal Glands; Adult; Age Factors; Androstenedione; Child; Child, Preschool; Clomiphene

1975
Biologic activity and metabolism of androgenic hormones: the role of the adrenal androgens.
    Bulletin of the New York Academy of Medicine, 1977, Volume: 53, Issue:4

    Topics: Adrenal Glands; Androgens; Dehydroepiandrosterone; Dihydrotestosterone; Female; Hair; Humans; Male;

1977
[Male puberty].
    La Revue du praticien, 1977, Sep-11, Volume: 27, Issue:39

    Topics: 17-Ketosteroids; Adolescent; Child; Chorionic Gonadotropin; Clomiphene; Dehydroepiandrosterone; Estr

1977
Preadolescent and adolescent endocrinology: physiology and physiopathology. II. Hormonal changes during abnormal pubertal development.
    American journal of diseases of children (1960), 1978, Volume: 132, Issue:8

    Topics: Adolescent; Adrenocortical Hyperfunction; Androgen Antagonists; Child; Dehydroepiandrosterone; Estra

1978
A child with pituitary gigantism and precocious adrenarche: does GH and/or PRL advance the onset of adrenarche?
    Endocrinologia japonica, 1992, Volume: 39, Issue:3

    Topics: Adenoma; Adrenal Cortex; Androgens; Child; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; D

1992
Use of a potent, long acting agonist of gonadotropin-releasing hormone in the treatment of precocious puberty.
    Endocrine reviews, 1986, Volume: 7, Issue:1

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Bone Development; Child; Child, Preschool; Dehydroe

1986
Virilizing adrenocortical tumors in childhood: eight cases and a review of the literature.
    Pediatrics, 1985, Volume: 76, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma; Adenoma; Adrenal Cortex Neoplasms; Child

1985

Trials

7 trials available for dehydroepiandrosterone and Puberty, Precocious

ArticleYear
Increased adrenal androgen levels in patients with Prader-Willi syndrome are associated with insulin, IGF-I, and leptin, but not with measures of obesity.
    Hormone research, 2002, Volume: 58, Issue:5

    Topics: Adolescent; Adrenal Glands; Analysis of Variance; Androgens; Androstenedione; Anthropometry; Body Co

2002
Usefulness of an ACTH test in the diagnosis of nonclassical 21-hydroxylase deficiency among children presenting with premature pubarche.
    Hormone research, 1995, Volume: 44, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Age of O

1995
Serum leptin levels in patients with progressive central precocious puberty.
    Pediatric research, 1999, Volume: 46, Issue:1

    Topics: Androstenedione; Body Height; Body Mass Index; Child; Child, Preschool; Dehydroepiandrosterone; Estr

1999
Corticotropin-releasing hormone: a potent androgen secretagogue in girls with hyperandrogenism after precocious pubarche.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:12

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Androgens; Body Mass Index; Corticotropin-Releasing

1999
Rapid corticotropin versus corticotropin-releasing hormone test in girls with precocious pubarche.
    Journal of pediatric endocrinology & metabolism : JPEM, 2002, Volume: 15, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Androstenedione; Child; Child, Preschool;

2002
A dose finding study of a super long-acting luteinizing hormone-releasing hormone analog (leuprolide acetate depot, TAP-144-SR) in the treatment of central precocious puberty. The TAP-144-SR CPP Study Group.
    Endocrinologia japonica, 1991, Volume: 38, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Analysis of Variance; Child; Child, Pres

1991
Effect of treatment with medroxyprogesterone acetate (Provera) on testicular function.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:5

    Topics: Adolescent; Adult; Androgens; Child; Child, Preschool; Clinical Trials as Topic; Dehydroepiandroster

1968

Other Studies

68 other studies available for dehydroepiandrosterone and Puberty, Precocious

ArticleYear
A cross-sectional survey of adrenal steroid hormones among overweight/obese boys according to puberty stage.
    BMC pediatrics, 2019, 11-06, Volume: 19, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Cortex Hormones; Age Factors; Androstenedione; Chi

2019
Adrenarche in Silver-Russell Syndrome: Timing and Consequences.
    The Journal of clinical endocrinology and metabolism, 2017, 11-01, Volume: 102, Issue:11

    Topics: Adolescent; Adrenarche; Age Factors; Child; Dehydroepiandrosterone; Female; Follow-Up Studies; Hormo

2017
Causes, patterns and severity of androgen excess in 487 consecutively recruited pre- and post-pubertal children.
    European journal of endocrinology, 2019, Mar-01, Volume: 180, Issue:3

    Topics: Adolescent; Androgens; Androstenedione; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroepia

2019
Depression, immune function, and early adrenarche in children.
    Psychoneuroendocrinology, 2016, Volume: 63

    Topics: Adrenarche; C-Reactive Protein; Child; Child Behavior; Cohort Studies; Dehydroepiandrosterone; Depre

2016
[Psychological behavior of girls with idiopathic central precocious puberty before and after treatment with gonadotropin-releasing hormone analogue].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2008, Volume: 37, Issue:3

    Topics: Child; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Gonadotropin-Releasing Hormon

2008
Characteristics of children with premature pubarche in the new york metropolitan area.
    Hormone research, 2008, Volume: 70, Issue:3

    Topics: Age Determination by Skeleton; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroepiandrostero

2008
Inactivating PAPSS2 mutations in a patient with premature pubarche.
    The New England journal of medicine, 2009, May-28, Volume: 360, Issue:22

    Topics: Androgens; Androstenedione; Child; Dehydroepiandrosterone; Diagnosis, Differential; Female; Heterozy

2009
Clinical and metabolic findings in a 6-year-old boy with a Leydig cell tumour.
    Acta paediatrica (Oslo, Norway : 1992), 2011, Volume: 100, Issue:12

    Topics: Androsterone; Antineoplastic Agents, Hormonal; Child; Dehydroepiandrosterone; Etiocholanolone; Human

2011
[Urinary elimination of 17-ketosteroids and dehydroisoandrosterone in patients with various endocrine diseases (Addison's disease, Cushing's disease, Cushing's syndrome, precocious puberty caused by congenital adrenal hyperplasia, acromegaly)].
    Il Progresso medico, 1955, Jun-30, Volume: 11, Issue:12

    Topics: 17-Ketosteroids; Acromegaly; Addison Disease; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperf

1955
Familial male sexual precocity: report of the eleventh kindred found, with observations on blood group linkage and urinary C19-steroid excretion.
    The Journal of clinical endocrinology and metabolism, 1962, Volume: 22

    Topics: Anatomy; Androsterone; Blood Group Antigens; Dehydroepiandrosterone; Humans; Male; Puberty, Precocio

1962
Urinary C19 steroids in two girls with precocious sexual hair.
    The Journal of clinical endocrinology and metabolism, 1963, Volume: 23

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Androsterone; Dehydroepiandrosterone; Female; Hair; Humans

1963
A VIRILIZING ADRENAL TUMOR IN A PREPUBERTAL BOY.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: 17-Ketosteroids; Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Cong

1964
Premature pubarche as an indicator of how body weight influences the onset of adrenarche.
    European journal of pediatrics, 2004, Volume: 163, Issue:2

    Topics: Adrenal Hyperplasia, Congenital; Birth Weight; Body Weight; Child; Child, Preschool; Dehydroepiandro

2004
Refining hormonal diagnosis of type II 3beta-hydroxysteroid dehydrogenase deficiency in patients with premature pubarche and hirsutism based on HSD3B2 genotyping.
    The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:3

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Adolesc

2005
[Relationship between serum dehydroepiandrosterone levels and female precocious puberty].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2005, Volume: 34, Issue:4

    Topics: Child; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Enzyme-Linked Immunosorbent Assay; Fe

2005
ACTH receptor promoter polymorphism associates with severity of premature adrenarche and modulates hypothalamo-pituitary-adrenal axis in children.
    Pediatric research, 2008, Volume: 63, Issue:4

    Topics: Adrenarche; Adrenocorticotropic Hormone; Case-Control Studies; Child; Dehydroepiandrosterone; Female

2008
[The succession of precocious puberty and Stein-Leventhal syndrome].
    Helvetica paediatrica acta, 1982, Volume: 37, Issue:2

    Topics: Androstenedione; Child, Preschool; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Medroxypr

1982
Premature thelarche.
    Archives of disease in childhood, 1982, Volume: 57, Issue:8

    Topics: Age Factors; Breast; Child; Child, Preschool; Dehydroepiandrosterone; Female; Humans; Infant; Pubert

1982
Adrenarche as a cause of benign pseudopuberty in boys.
    The Journal of pediatrics, 1982, Volume: 101, Issue:6

    Topics: Adrenal Glands; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hum

1982
[Does adrenarche really play a determining role in pubertal development? A study of the dissociations between adrenarche and gonadarche. The failure of dehydroepiandrosterone sulfate treatment in delayed adrenarche].
    Annales d'endocrinologie, 1982, Volume: 43, Issue:6

    Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Diseases; Androgens; Child; Dehydroepiandrosterone; Dehyd

1982
Endocrine characteristics of adolescent menstrual cycles: impact of early menarche.
    Journal of steroid biochemistry, 1984, Volume: 20, Issue:1

    Topics: Adolescent; Age Factors; Body Composition; Child; Dehydroepiandrosterone; Estradiol; Female; Follicl

1984
Sexual precocity in a female infant due to feminizing adrenal carcinoma.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:1

    Topics: Adrenal Gland Neoplasms; Dehydroepiandrosterone; Female; Follow-Up Studies; Humans; Infant; Karyotyp

1980
Evidence for dissociation between adrenarche and gonadarche: studies in patients with idiopathic precocious puberty, gonadal dysgenesis, isolated gonadotropin deficiency, and constitutionally delayed growth and adolescence.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:3

    Topics: Adolescent; Adrenal Glands; Adult; Androgens; Child; Child, Preschool; Dehydroepiandrosterone; Dehyd

1980
Lack of effect of oestrogens on adrenal androgen secretion in children and adolescents with a comment on oestrogens and pubic hair growth.
    Clinical endocrinology, 1981, Volume: 14, Issue:3

    Topics: Adrenal Cortex; Androgens; Androstenedione; Child; Child, Preschool; Dehydroepiandrosterone; Dehydro

1981
Short-term treatment of idiopathic precocious puberty with a long-acting analogue of luteinizing hormone-releasing hormone. A preliminary report.
    The New England journal of medicine, 1981, Dec-24, Volume: 305, Issue:26

    Topics: Child; Child, Preschool; Dehydroepiandrosterone; Estradiol; Female; Follicle Stimulating Hormone; Go

1981
Premature thelarche: a possible adrenal disorder.
    Archives of disease in childhood, 1982, Volume: 57, Issue:3

    Topics: 17-Ketosteroids; Adrenal Gland Diseases; Age Determination by Skeleton; Body Height; Child; Child, P

1982
Early polycystic ovary-like syndrome in girls with central precocious puberty and exaggerated adrenal response.
    European journal of endocrinology, 1995, Volume: 133, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adrenocorticotropic Horm

1995
High prevalence of abnormal adrenal response in girls with central precocious puberty at early pubertal stages.
    European journal of endocrinology, 1995, Volume: 133, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Adrenal

1995
Isolated precocious pubarche: an approach.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 79, Issue:2

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Adrenal

1994
Plasma 3 alpha-androstanediol glucuronide in precocious adrenarche.
    Journal of endocrinological investigation, 1993, Volume: 16, Issue:2

    Topics: Androstane-3,17-diol; Androstenedione; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroepian

1993
The pattern of gonadotropin and estradiol secretion in exaggerated thelarche.
    Acta endocrinologica, 1993, Volume: 128, Issue:4

    Topics: Analysis of Variance; Bone Development; Breast; Child; Child, Preschool; Circadian Rhythm; Dehydroep

1993
Studies of 3 beta-hydroxysteroid dehydrogenase genes in infants and children manifesting premature pubarche and increased adrenocorticotropin-stimulated delta 5-steroid levels.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:11

    Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adrenal Hyperplasia, Congenital; Adre

1996
Girls diagnosed with premature pubarche show an exaggerated ovarian androgen synthesis from the early stages of puberty: evidence from gonadotropin-releasing hormone agonist testing.
    Fertility and sterility, 1997, Volume: 67, Issue:5

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adolescent; Androgens; Androstenedione;

1997
The molecular basis of premature adrenarche: an hypothesis.
    Acta paediatrica (Oslo, Norway : 1992). Supplement, 1999, Volume: 88, Issue:433

    Topics: Adrenal Glands; Child; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Female; Humans; Phosp

1999
[Precocious puberty caused by a testicular Leydig cell tumor].
    Orvosi hetilap, 2001, Jan-28, Volume: 142, Issue:4

    Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Child, Preschool; Dehydroepiandrostero

2001
[Telarca and premature puberty].
    Minerva pediatrica, 1976, Jun-09, Volume: 28, Issue:20

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Breast; Child; Dehydroepiandrosterone; Female; Humans; I

1976
Hormonal changes during puberty. IV. Longitudinal study of acrenal androgen secretions.
    Hormone research, 1976, Volume: 7, Issue:4-5

    Topics: Addison Disease; Child; Dehydroepiandrosterone; Female; Humans; Male; Puberty; Puberty, Precocious;

1976
Secretion of the adrenal androgen, dehydroepiandrosterone sulfate, during normal infancy, childhood, and adolescence, in sick infants, and in children with endocrinologic abnormalities.
    The Journal of pediatrics, 1977, Volume: 90, Issue:5

    Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Function Tests; Adrenocortical Hyperfunction; Child; Chil

1977
Proceedings: Maturation of the adrenal androgen secretion during puberty.
    Hormone research, 1975, Volume: 6, Issue:5-6

    Topics: Addison Disease; Adolescent; Age Determination by Skeleton; Child; Dehydroepiandrosterone; Female; H

1975
Adrenal steroidogenic defects in children with precocious pubarche.
    Hormone research, 1992, Volume: 37, Issue:4-5

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Adrenal Glands;

1992
Melatonin secretion during adrenarche in normal human puberty and in pubertal disorders.
    Journal of pineal research, 1992, Volume: 12, Issue:2

    Topics: Adolescent; Analysis of Variance; Child; Child, Preschool; Circadian Rhythm; Dehydroepiandrosterone;

1992
Identification of nonclassical 21-hydroxylase deficiency in girls with precocious pubarche.
    Journal of endocrinological investigation, 1991, Volume: 14, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Adrenocorticot

1991
Excess weight and precocious pubarche in children: alterations of the adrenocortical hormones.
    Journal of the American College of Nutrition, 1991, Volume: 10, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenal Cortex Hormones;

1991
3 alpha-Androstanediol glucuronide in premature and normal pubarche.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:1

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Andro

1991
Treatment of children with central precocious puberty by a slow-release gonadotropin-releasing hormone agonist.
    European journal of pediatrics, 1990, Volume: 149, Issue:5

    Topics: Body Height; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Delaye

1990
Nonclassical 3 beta-hydroxysteroid dehydrogenase deficiency in young girls with hirsutism and premature pubarche.
    Endocrinologia japonica, 1990, Volume: 37, Issue:5

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Androst

1990
Lack of adrenarche in two children with precocious puberty secondary to hypothalamic hamartoma.
    Hormone research, 1989, Volume: 31, Issue:5-6

    Topics: Adrenal Glands; Child, Preschool; Dehydroepiandrosterone; Female; Hamartoma; Hormones; Humans; Hypot

1989
Serum C-19 steroid sulphates in females with clinical hyperandrogenism.
    Journal of steroid biochemistry, 1989, Volume: 34, Issue:1-6

    Topics: Adolescent; Adult; Androgens; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroepiandrosteron

1989
Changes in steroid pattern following acute and chronic adrenocorticotropin administration in premature adrenarche.
    Journal of steroid biochemistry, 1989, Volume: 32, Issue:2

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone;

1989
Premature adrenarche. Clinical and diagnostic features.
    Clinical pediatrics, 1986, Volume: 25, Issue:1

    Topics: Adrenal Glands; Age Factors; Black People; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroe

1986
Adrenarche and skeletal maturation during luteinizing hormone releasing hormone analogue suppression of gonadarche.
    The Journal of clinical investigation, 1986, Volume: 77, Issue:1

    Topics: Adrenal Cortex; Age Determination by Skeleton; Androgens; Body Height; Child; Dehydroepiandrosterone

1986
Changes in growth and serum growth hormone and plasma somatomedin-C levels during suppression of gonadal sex steroid secretion in girls with central precocious puberty.
    The Journal of clinical endocrinology and metabolism, 1988, Volume: 66, Issue:1

    Topics: Age Determination by Skeleton; Body Height; Body Weight; Bone Development; Child, Preschool; Dehydro

1988
Treatment of central precocious puberty with an LHRH agonist (Buserelin): effect on growth and bone maturation after three years of treatment.
    Hormone research, 1987, Volume: 28, Issue:2-4

    Topics: Aging; Body Height; Bone Development; Buserelin; Child; Dehydroepiandrosterone; Dehydroepiandrostero

1987
17-Hydroxyprogesterone responses to adrenocorticotropin in children with premature adrenarche.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 60, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Androstenedio

1985
Adrenal steroid secretion in girls with pseudoprecocious puberty due to autonomous ovarian cysts.
    The Journal of clinical endocrinology and metabolism, 1986, Volume: 63, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone;

1986
Precocious puberty following severe head trauma.
    American journal of diseases of children (1960), 1985, Volume: 139, Issue:5

    Topics: Child; Craniocerebral Trauma; Dehydroepiandrosterone; Estradiol; Female; Gonadotropin-Releasing Horm

1985
Steroid metabolism in premature pubarche and virilizing adrenal hyperplasia.
    The Journal of pediatrics, 1967, Volume: 71, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Androgens;

1967
Steroid excretion patterns in 3 cases of idiopathic precocious puberty.
    Helvetica paediatrica acta, 1966, Volume: 21, Issue:3

    Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Androgens; Child; Chromatography

1966
[Excretion of C-19 and C21 steroids in the urine under normal and pathological conditions of development and maturation].
    Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimentelle Chirurgie, 1967, Volume: 142, Issue:3

    Topics: 17-Ketosteroids; Adolescent; Adult; Age Factors; Androsterone; Carbon Isotopes; Child; Child, Presch

1967
Studies on testicular function in children: plasma concentrations of testosterone, dehydroepiandrosterone and its sulfate before and after stimulation with human chorionic gonadotrophin. (1).
    Steroids, 1968, Volume: 12, Issue:6

    Topics: Adolescent; Age Factors; Child; Child, Preschool; Chorionic Gonadotropin; Chromatography, Thin Layer

1968
[Suprarenal virilism].
    Munchener medizinische Wochenschrift (1950), 1970, Oct-16, Volume: 112, Issue:42

    Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Dehydroep

1970
Isosexual pseudoprecocity in a 6-year-old boy with a testicular interstitial cell adenoma.
    The Journal of pediatrics, 1972, Volume: 80, Issue:2

    Topics: 17-Ketosteroids; Androstanes; Child; Chorionic Gonadotropin; Dehydroepiandrosterone; Humans; Hydroco

1972
Conjugated and unconjugated plasma androgens in normal children.
    Pediatric research, 1972, Volume: 6, Issue:2

    Topics: 17-Ketosteroids; Adolescent; Adult; Age Factors; Androgens; Androstanes; Androsterone; Bromine; Carb

1972
The treatment of precocious puberty with cyproterone acetate.
    Acta endocrinologica, 1973, Volume: 74, Issue:2

    Topics: Androsterone; Body Height; Body Weight; Bone Development; Child; Child, Preschool; Cyproterone; Dehy

1973
Plasma androgens and LH in scoliotic patients with premature pubarche.
    The Journal of clinical endocrinology and metabolism, 1974, Volume: 38, Issue:3

    Topics: Adolescent; Androstenedione; Blood Proteins; Child; Child, Preschool; Dehydroepiandrosterone; Dexame

1974
[Case of precocious puberty with neoplasm in the region of the mamillary bodies: treatment by interstitial radiotherapy (author's transl)].
    Journal of neuro-visceral relations, 1971, Volume: 0, Issue:0

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Bone Development; Brain Neoplasms; Child; Child, Prescho

1971
[Adrenal hirsutism (3beta-hydroxysteroid dehydrogenase deficiency). Studies using a chromatographic separation of the 17-ketosteroid fraction in the urine. 1. Dehydroepiandrosterone-forming adrenocortical adenoma].
    Endokrinologie, 1967, Volume: 52, Issue:1

    Topics: 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocorticotro

1967
Plasma 17-ketosteroids and 17-beta hydroxysteroids in girls with premature development of sexual hair.
    The Journal of pediatrics, 1971, Volume: 79, Issue:2

    Topics: 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Androstanes; Child; Child,

1971