dehydroepiandrosterone has been researched along with Psychoses in 10 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recent investigation in schizophrenia indicated dehydroepiandrosterone (DHEA) levels to be inversely correlated with extrapyramidal symptomatology (EPS)." | 9.11 | Improvement of extrapyramidal symptoms following dehydroepiandrosterone (DHEA) administration in antipsychotic treated schizophrenia patients: a randomized, double-blind placebo controlled trial. ( Abramovitch, Y; Assael-Amir, M; Ebert, T; Kotler, M; Maayan, R; Nachshoni, T; Strous, RD; Weizman, A, 2005) |
| "Recent investigation in schizophrenia indicated dehydroepiandrosterone (DHEA) levels to be inversely correlated with extrapyramidal symptomatology (EPS)." | 5.11 | Improvement of extrapyramidal symptoms following dehydroepiandrosterone (DHEA) administration in antipsychotic treated schizophrenia patients: a randomized, double-blind placebo controlled trial. ( Abramovitch, Y; Assael-Amir, M; Ebert, T; Kotler, M; Maayan, R; Nachshoni, T; Strous, RD; Weizman, A, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Garner, B | 1 |
| Phillips, LJ | 1 |
| Bendall, S | 1 |
| Hetrick, SE | 1 |
| Ritsner, MS | 1 |
| Gibel, A | 1 |
| Shleifer, T | 1 |
| Boguslavsky, I | 1 |
| Zayed, A | 1 |
| Maayan, R | 3 |
| Weizman, A | 3 |
| Lerner, V | 1 |
| Kulkarni, J | 1 |
| de Castella, A | 1 |
| Headey, B | 1 |
| Marston, N | 1 |
| Sinclair, K | 1 |
| Lee, S | 1 |
| Gurvich, C | 1 |
| Fitzgerald, PB | 1 |
| Burger, H | 1 |
| Harris, DS | 1 |
| Wolkowitz, OM | 1 |
| Reus, VI | 1 |
| Howard, JM | 1 |
| Nachshoni, T | 1 |
| Ebert, T | 1 |
| Abramovitch, Y | 1 |
| Assael-Amir, M | 1 |
| Kotler, M | 1 |
| Strous, RD | 1 |
| Hui, X | 1 |
| Zhou, CH | 1 |
| Wang, MW | 1 |
| Magrini, G | 1 |
| Gasperi, M | 1 |
| du Pan, RM | 1 |
| Baumann, P | 1 |
| Felber, JP | 1 |
| Yagorowski, Y | 1 |
| Grupper, D | 1 |
| Weiss, M | 1 |
| Shtaif, B | 1 |
| Kaoud, MA | 1 |
| Oertel, GW | 1 |
| Benes, P | 1 |
| Schirazi, M | 1 |
| Holzmann, H | 1 |
| Hoffmann, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Addition of Both Pregnenolone and L-theanine to Ongoing Antipsychotic Treatment for Schizophrenia and Schizoaffective Disorders: an 8-week, Randomized, Double-blind, Placebo-controlled Multicenter Study[NCT01831986] | 60 participants (Anticipated) | Interventional | 2011-01-31 | Enrolling by invitation | |||
| Efficacy and Safety of Pregnenolone Augmentation in the Management of Schizophrenia Patients: a Randomised Double-Blind Placebo-Controlled Trial[NCT00174889] | Phase 1 | 60 participants | Interventional | 2005-01-31 | Completed | ||
| A Randomised Controlled Trial of Selective Estrogen Receptor Modulators (SERMs) - A Potential Treatment for Psychotic Symptoms of Schizophrenia in Men?[NCT01481883] | Phase 4 | 13 participants (Actual) | Interventional | 2012-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for dehydroepiandrosterone and Psychoses
| Article | Year |
|---|---|
Antiglucocorticoid and related treatments for psychosis.
Topics: Dehydroepiandrosterone; Dexamethasone; Glucocorticoids; Humans; Hypothalamo-Hypophyseal System; Keto | 2016 |
Glucocorticoid receptor and treatment of psychotic major depression.
Topics: Animals; Brain; Dehydroepiandrosterone; Depressive Disorder, Major; Humans; Metyrapone; Mifepristone | 2005 |
3 trials available for dehydroepiandrosterone and Psychoses
| Article | Year |
|---|---|
Pregnenolone and dehydroepiandrosterone as an adjunctive treatment in schizophrenia and schizoaffective disorder: an 8-week, double-blind, randomized, controlled, 2-center, parallel-group trial.
Topics: Adolescent; Adult; Antipsychotic Agents; Attention; Dehydroepiandrosterone; Dose-Response Relationsh | 2010 |
Pregnenolone and dehydroepiandrosterone as an adjunctive treatment in schizophrenia and schizoaffective disorder: an 8-week, double-blind, randomized, controlled, 2-center, parallel-group trial.
Topics: Adolescent; Adult; Antipsychotic Agents; Attention; Dehydroepiandrosterone; Dose-Response Relationsh | 2010 |
Pregnenolone and dehydroepiandrosterone as an adjunctive treatment in schizophrenia and schizoaffective disorder: an 8-week, double-blind, randomized, controlled, 2-center, parallel-group trial.
Topics: Adolescent; Adult; Antipsychotic Agents; Attention; Dehydroepiandrosterone; Dose-Response Relationsh | 2010 |
Pregnenolone and dehydroepiandrosterone as an adjunctive treatment in schizophrenia and schizoaffective disorder: an 8-week, double-blind, randomized, controlled, 2-center, parallel-group trial.
Topics: Adolescent; Adult; Antipsychotic Agents; Attention; Dehydroepiandrosterone; Dose-Response Relationsh | 2010 |
Estrogens and men with schizophrenia: is there a case for adjunctive therapy?
Topics: Adult; Antipsychotic Agents; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Double-Blind | 2011 |
Improvement of extrapyramidal symptoms following dehydroepiandrosterone (DHEA) administration in antipsychotic treated schizophrenia patients: a randomized, double-blind placebo controlled trial.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Dehydroepiandrosterone; Double-Blind Method; Fema | 2005 |
5 other studies available for dehydroepiandrosterone and Psychoses
| Article | Year |
|---|---|
Movement disorder, memory, psychiatric symptoms and serum DHEA levels in schizophrenic and schizoaffective patients.
Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Dehydroepiandrosterone; Female; Humans; Hydrocort | 2001 |
Testosterone and psychosis.
Topics: Biological Evolution; Dehydroepiandrosterone; Female; Humans; Male; Psychotic Disorders; Risk Factor | 2004 |
Effects of chronic neuroleptic therapy on human PRL secretion and testicular function.
Topics: Adolescent; Adult; Antiparkinson Agents; Antipsychotic Agents; Bromocriptine; Chorionic Gonadotropin | 1981 |
Basal plasma dehydroepiandrosterone sulfate level: a possible predictor for response to electroconvulsive therapy in depressed psychotic inpatients.
Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depressive Disorder, Major; Electroco | 2000 |
Interaction between dehydroepiandrosterone, cyclic adenosine-3',5'-monophosphate and glucose-6-phosphate-dehydrogenase in normal and diseased subjects.
Topics: Adult; Cyclic AMP; Dehydroepiandrosterone; Female; Glucosephosphate Dehydrogenase; Humans; Hyperlipi | 1974 |