dehydroepiandrosterone has been researched along with Prostatic Intraepithelial Neoplasia in 2 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Prostatic Intraepithelial Neoplasia: A premalignant change arising in the prostatic epithelium, regarded as the most important and most likely precursor of prostatic adenocarcinoma. The neoplasia takes the form of an intra-acinar or ductal proliferation of secretory cells with unequivocal nuclear anaplasia, which corresponds to nuclear grade 2 and 3 invasive prostate cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cultures from high grade prostatic intraepithelial neoplasia (HGPIN) have been established and immortalized by HPV-18 infection." | 1.30 | Growth of HPV-18 immortalized human prostatic intraepithelial neoplasia cell lines. Influence of IL-10, follistatin, activin-A, and DHT. ( Garcia, FU; Liu, A; Rhim, JS; Stearns, ME; Wang, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Christov, KT | 1 |
| Moon, RC | 1 |
| Lantvit, DD | 1 |
| Boone, CW | 1 |
| Kelloff, GJ | 1 |
| Steele, VE | 1 |
| Lubet, RA | 1 |
| Pezzuto, JM | 1 |
| Wang, M | 1 |
| Liu, A | 1 |
| Garcia, FU | 1 |
| Rhim, JS | 1 |
| Stearns, ME | 1 |
2 other studies available for dehydroepiandrosterone and Prostatic Intraepithelial Neoplasia
| Article | Year |
|---|---|
Prostate intraepithelial neoplasia in Noble rats, a potential intermediate endpoint for chemoprevention studies.
Topics: Animals; Antineoplastic Agents; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Drug Scree | 2004 |
Growth of HPV-18 immortalized human prostatic intraepithelial neoplasia cell lines. Influence of IL-10, follistatin, activin-A, and DHT.
Topics: Activins; Adjuvants, Immunologic; Androgens; Animals; Blotting, Western; Cell Adhesion; Cell Divisio | 1999 |