dehydroepiandrosterone has been researched along with Precancerous Conditions in 25 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Precancerous Conditions: Pathological conditions that tend eventually to become malignant.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Comparative investigations of the urinary excretion of different 17-ketosteroids in healthy women and patients suffering from mastopathia fibrocystica and/or mammary carcinomas had the following results: 1." | 7.65 | The excretion of 17-ketosteroids in patients suffering from mastopathia fibrocystica and mammary carcinomas. ( Görlich, M; Heise, E; Hindy, I; Pradja, N, 1975) |
| "Measurement of the excretion of total 17-ketosteroids, androsterone, etiocholanolone, and dehydroepiandrosterone demonstrate in contrast to the well known age dependency of normal women in cases of both mastopathia and breast cancer the following results: 1." | 3.65 | Investigation of 17-ketosteriod excretion in mastopathia and premenopausal breast cancer. ( Eckhardt, S; Hindy, I; Prajda, N; Sellei, C; Tapolcsányi, L, 1975) |
| "Comparative investigations of the urinary excretion of different 17-ketosteroids in healthy women and patients suffering from mastopathia fibrocystica and/or mammary carcinomas had the following results: 1." | 3.65 | The excretion of 17-ketosteroids in patients suffering from mastopathia fibrocystica and mammary carcinomas. ( Görlich, M; Heise, E; Hindy, I; Pradja, N, 1975) |
| "This is the first study of colon cancer carcinogenesis demonstrating that DHEA treatment can decrease the number of ACF without apparently modifying their malignant potential." | 1.31 | Chemoprevention of precursors to colon cancer by dehydroepiandrosterone (DHEA). ( Matsuhashi, N; Nagase, H; Nakagama, H; Nakajima, A; Ochiai, M; Omura, M; Osawa, E; Sekihara, H; Ueno, N; Wada, K; Yoshida, S, 2002) |
| " However, a dose-response reduction in invasive carcinoma growth was observed for both DFMO, an inhibitor of ornithine decarboxylase, and DHEA, the primary steroid precursor to both androgens and estrogens in primates." | 1.31 | 2-difluoromethylornithine and dehydroepiandrosterone inhibit mammary tumor progression but not mammary or prostate tumor initiation in C3(1)/SV40 T/t-antigen transgenic mice. ( Anver, MR; Green, JE; Kelloff, G; Lubet, R; Moon, RC; Shibata, E; Shibata, MA, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (52.00) | 18.7374 |
| 1990's | 10 (40.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Osawa, E | 1 |
| Nakajima, A | 1 |
| Yoshida, S | 1 |
| Omura, M | 1 |
| Nagase, H | 1 |
| Ueno, N | 1 |
| Wada, K | 1 |
| Matsuhashi, N | 1 |
| Ochiai, M | 1 |
| Nakagama, H | 1 |
| Sekihara, H | 1 |
| Shibata, M | 1 |
| Hasegawa, R | 1 |
| Imaida, K | 1 |
| Hagiwara, A | 1 |
| Ogawa, K | 1 |
| Hirose, M | 2 |
| Ito, N | 5 |
| Shirai, T | 2 |
| Pascale, RM | 2 |
| Simile, MM | 2 |
| De Miglio, MR | 2 |
| Nufris, A | 2 |
| Seddaiu, MA | 3 |
| Muroni, MR | 2 |
| Danni, O | 1 |
| Rao, KN | 3 |
| Feo, F | 4 |
| Simile, M | 1 |
| Daino, L | 3 |
| Shibata, MA | 2 |
| Asakawa, E | 1 |
| Fukushima, S | 1 |
| Mayer, D | 2 |
| Metzger, C | 1 |
| Leonetti, P | 1 |
| Beier, K | 1 |
| Benner, A | 1 |
| Bannasch, P | 3 |
| Nehrbass, D | 1 |
| Klimek, F | 1 |
| Green, JE | 1 |
| Shibata, E | 1 |
| Moon, RC | 1 |
| Anver, MR | 1 |
| Kelloff, G | 1 |
| Lubet, R | 1 |
| Hindy, I | 2 |
| Prajda, N | 1 |
| Tapolcsányi, L | 1 |
| Sellei, C | 1 |
| Eckhardt, S | 1 |
| Görlich, M | 1 |
| Heise, E | 1 |
| Pradja, N | 1 |
| Godefroi, VC | 1 |
| Locke, ER | 1 |
| Singh, DV | 1 |
| Brooks, SC | 1 |
| Pascale, R | 2 |
| McKeating, JA | 1 |
| Davliakos, GP | 1 |
| Sudol, KS | 1 |
| Melhem, MF | 1 |
| Hamilton, SR | 1 |
| Gordon, GB | 1 |
| Floyd, J | 1 |
| Golightly, S | 1 |
| Pereira, MA | 1 |
| Khoury, MD | 1 |
| Zanardi, S | 1 |
| Valenti, G | 1 |
| Torrisi, R | 1 |
| Maisto, L | 1 |
| Nicolò, G | 1 |
| Barreca, A | 1 |
| Minuto, F | 1 |
| Boccardo, F | 1 |
| Thornton, M | 1 |
| Moore, MA | 5 |
| Thamavit, W | 3 |
| Tsuda, H | 2 |
| Sato, K | 1 |
| Ichihara, A | 1 |
| Garcea, R | 1 |
| Frassetto, S | 1 |
| Cozzolino, P | 1 |
| Ruggiu, ME | 1 |
| Weber, E | 1 |
| Hiasa, Y | 1 |
| Mezinova, NN | 2 |
| Krivets, NA | 1 |
| Wang, DY | 1 |
| Swain, MC | 1 |
| Hayward, JL | 1 |
| Bulbrook, RD | 1 |
| Bogdanova, AG | 2 |
25 other studies available for dehydroepiandrosterone and Precancerous Conditions
| Article | Year |
|---|---|
Chemoprevention of precursors to colon cancer by dehydroepiandrosterone (DHEA).
Topics: Adjuvants, Immunologic; Animals; Azoxymethane; beta Catenin; Carcinogens; Chemoprevention; Colonic N | 2002 |
Chemoprevention by dehydroepiandrosterone and indomethacin in a rat multiorgan carcinogenesis model.
Topics: Animals; Anticarcinogenic Agents; Dehydroepiandrosterone; Disease Models, Animal; Hyperplasia; Indom | 1995 |
Inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase activity and gene expression by dehydroepiandrosterone in preneoplastic liver nodules.
Topics: 17-Ketosteroids; Animals; Body Weight; Cholesterol; Dehydroepiandrosterone; Gene Expression; Hydroxy | 1995 |
Inhibition by dehydroepiandrosterone of growth and progression of persistent liver nodules in experimental rat liver carcinogenesis.
Topics: Animals; Body Weight; Dehydroepiandrosterone; Glucosephosphate Dehydrogenase; Liver; Liver Diseases; | 1995 |
Inhibition by dehydroepiandrosterone of butylated hydroxyanisole (BHA) promotion of rat-bladder carcinogenesis and enhancement of BHA-induced forestomach hyperplasia.
Topics: Animals; Body Weight; Butylated Hydroxyanisole; Dehydroepiandrosterone; DNA; Drug Synergism; Hyperpl | 1993 |
Differential expression of key enzymes of energy metabolism in preneoplastic and neoplastic rat liver lesions induced by N-nitrosomorpholine and dehydroepiandrosterone.
Topics: Animals; Carcinogens; Dehydroepiandrosterone; Energy Metabolism; Female; Glucosephosphate Dehydrogen | 1998 |
Insulin receptor substrate-1 is over-expressed in glycogenotic but not in amphophilic preneoplastic hepatic foci induced in rats by N-nitrosomorpholine and dehydroepiandrosterone.
Topics: Adenoma, Liver Cell; Animals; Carcinoma, Hepatocellular; Dehydroepiandrosterone; Female; Glycogen; I | 1999 |
2-difluoromethylornithine and dehydroepiandrosterone inhibit mammary tumor progression but not mammary or prostate tumor initiation in C3(1)/SV40 T/t-antigen transgenic mice.
Topics: Animals; Anticarcinogenic Agents; Antigens, Polyomavirus Transforming; Apoptosis; Cell Division; Deh | 2001 |
Investigation of 17-ketosteriod excretion in mastopathia and premenopausal breast cancer.
Topics: 17-Ketosteroids; Adult; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Fem | 1975 |
The excretion of 17-ketosteroids in patients suffering from mastopathia fibrocystica and mammary carcinomas.
Topics: 17-Ketosteroids; Adult; Age Factors; Aged; Androsterone; Breast Diseases; Breast Neoplasms; Cysts; D | 1975 |
The steroid alcohol and estrogen sulfotransferases in rodent and human mammary tumors.
Topics: Alcohols; Animals; Breast Neoplasms; Castration; Chick Embryo; Dehydroepiandrosterone; Estrogens; Es | 1975 |
Differential effects of dehydroepiandrosterone and deoxyribonucleosides on DNA synthesis and de novo cholesterogenesis in hepatocarcinogenesis in rats.
Topics: Animals; Cholesterol; Cocarcinogenesis; Dehydroepiandrosterone; Deoxyribonucleosides; DNA, Neoplasm; | 1991 |
Evaluation of dietary dehydroepiandrosterone for chemoprotection against tumorigenesis in premalignant colonic epithelium of male F344 rats.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Azoxymethane; Carcinogens; Colon; Colonic Neo | 1991 |
Prevention by chemopreventive agents of azoxymethane-induced foci of aberrant crypts in rat colon.
Topics: Acetylcysteine; Allyl Compounds; Animals; Anticarcinogenic Agents; Azoxymethane; Colon; Colonic Neop | 1991 |
Identification of breast cyst subpopulations: biochemical and morphological features.
Topics: Biopsy, Needle; Body Fluids; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Epidermal Growt | 1991 |
Modifying influence of dehydroepiandrosterone or butylated hydroxytoluene treatment on initiation and development stages of azaserine-induced acinar pancreatic preneoplastic lesions in the rat.
Topics: Animals; Azaserine; Butylated Hydroxytoluene; Dehydroepiandrosterone; Liver Neoplasms; Male; Pancrea | 1989 |
Modifying influence of dehydroepiandrosterone on the development of dihydroxy-di-n-propylnitrosamine-initiated lesions in the thyroid, lung and liver of F344 rats.
Topics: Animals; Body Weight; Carcinogens; Dehydroepiandrosterone; gamma-Glutamyltransferase; Glucosephospha | 1986 |
The influence of subsequent dehydroepiandrosterone, diaminopropane, phenobarbital, butylated hydroxyanisole and butylated hydroxytoluene treatment on the development of preneoplastic and neoplastic lesions in the rat initiated with di-hydroxy-di-n-propyl
Topics: Animals; Anisoles; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Carcinogens; Dehydroepiandros | 1986 |
Inhibition by dehydroepiandrosterone of liver preneoplastic foci formation in rats after initiation-selection in experimental carcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Dehydroepiandrosterone; Diethylnitrosamine; Female; Liver; Liver Neo | 1987 |
Enzyme histochemical and morphological phenotype of amphophilic foci and amphophilic/tigroid cell adenomas in rat liver after combined treatment with dehydroepiandrosterone and N-nitrosomorpholine.
Topics: Animals; Carcinogens; Dehydroepiandrosterone; Drug Interactions; Liver; Liver Neoplasms; Male; Nitro | 1988 |
Early lesions induced by DHPN in Syrian golden hamsters: influence of concomitant Opisthorchis infestation, dehydroepiandrosterone or butylated hydroxyanisole administration.
Topics: Animals; Butylated Hydroxyanisole; Chemical and Drug Induced Liver Injury; Cricetinae; Dehydroepiand | 1988 |
[The concentration of 17-neutral ketosteroids and dehydroepiandrosterone in the urine of patients with precancerous diseases and cancer of the uterine cervix].
Topics: 17-Ketosteroids; Adult; Dehydroepiandrosterone; Female; Humans; Middle Aged; Precancerous Conditions | 1969 |
Hormones in the aetiology and clinical course of breast cancer.
Topics: Adult; Age Factors; Aged; Androgens; Animals; Breast Neoplasms; Carcinogens; Dehydroepiandrosterone; | 1972 |
[Excretion of adrenal cortex hormones in precancerous processes and uterine cancer].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Androsterone; Chromatography, Thin Layer; C | 1973 |
[Influence of age and menopause duration on the excretion of steroid hormones in precancerous conditions and cancer of the breast].
Topics: Adult; Age Factors; Androsterone; Breast Diseases; Breast Neoplasms; Dehydroepiandrosterone; Etiocho | 1974 |