dehydroepiandrosterone has been researched along with Polymyalgia Rheumatica in 4 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Polymyalgia Rheumatica: A syndrome in the elderly characterized by proximal joint and muscle pain, high erythrocyte sedimentation rate, and a self-limiting course. Pain is usually accompanied by evidence of an inflammatory reaction. Women are affected twice as commonly as men and Caucasians more frequently than other groups. The condition is frequently associated with GIANT CELL ARTERITIS and some theories pose the possibility that the two diseases arise from a single etiology or even that they are the same entity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the correlation between inflammatory cytokines and adrenal hormones in patients with polymyalgia rheumatica (PMR) and to compare the ratio of serum cortisol and androstenedione (ASD) or dehydroepiandrosterone sulphate (DHEAS) in normal subjects with PMR patients." | 3.70 | The adrenal steroid status in relation to inflammatory cytokines (interleukin-6 and tumour necrosis factor) in polymyalgia rheumatica. ( Cutolo, M; Georgi, J; Glück, T; Helmke, K; Lang, B; Schölmerich, J; Straub, RH; Vaith, P, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cutolo, M | 3 |
| Sulli, A | 1 |
| Pizzorni, C | 1 |
| Craviotto, C | 1 |
| Prete, C | 1 |
| Foppiani, L | 2 |
| Salvarani, C | 1 |
| Straub, RH | 2 |
| Seriolo, B | 1 |
| Minuto, F | 1 |
| Pacheco, MJ | 1 |
| Amado, JA | 1 |
| Lopez-Hoyos, M | 1 |
| Blanco, R | 1 |
| Garcia-Unzueta, MT | 1 |
| Rodriguez-Valverde, V | 1 |
| Martinez-Taboada, VM | 1 |
| Glück, T | 1 |
| Georgi, J | 1 |
| Helmke, K | 1 |
| Schölmerich, J | 1 |
| Vaith, P | 1 |
| Lang, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Is the Melanocortin System Involved in Inflammatory Resolution[NCT05681676] | 9 participants (Actual) | Observational | 2012-03-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for dehydroepiandrosterone and Polymyalgia Rheumatica
| Article | Year |
|---|---|
Cortisol, dehydroepiandrosterone sulfate, and androstenedione levels in patients with polymyalgia rheumatica during twelve months of glucocorticoid therapy.
Topics: Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Aged; Aging; Androsten | 2002 |
Hypothalamic-pituitary-adrenal axis impairment in the pathogenesis of rheumatoid arthritis and polymyalgia rheumatica.
Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Adult; Aged; Animals; Arthritis, Rheumato | 2002 |
Hypothalamic-pituitary-adrenocortical axis function in patients with polymyalgia rheumatica and giant cell arteritis.
Topics: 17-alpha-Hydroxyprogesterone; Acute-Phase Reaction; Adrenocorticotropic Hormone; Aged; Aged, 80 and | 2003 |
The adrenal steroid status in relation to inflammatory cytokines (interleukin-6 and tumour necrosis factor) in polymyalgia rheumatica.
Topics: Adrenal Glands; Aged; Androstenedione; Dehydroepiandrosterone; Hormones; Humans; Hydrocortisone; Hyp | 2000 |