dehydroepiandrosterone has been researched along with Plasmodium falciparum Malaria in 3 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the behavior of cortisol and dehydroepiandrosterone (DHEA) in 24 patients with uncomplicated Plasmodium falciparum malaria of the Evandro Chagas Institute, Belém, Pará, Brazil." | 7.73 | Some aspects of the behavior of the hypothalamus-pituitary-adrenal axis in patients with uncomplicated Plasmodium falciparum malaria: Cortisol and dehydroepiandrosterone levels. ( de Mendonça, BB; de Souza, JM; Libonati, RM; Maués, JA; Quaresma, JA, 2006) |
| "We studied the behavior of cortisol and dehydroepiandrosterone (DHEA) in 24 patients with uncomplicated Plasmodium falciparum malaria of the Evandro Chagas Institute, Belém, Pará, Brazil." | 3.73 | Some aspects of the behavior of the hypothalamus-pituitary-adrenal axis in patients with uncomplicated Plasmodium falciparum malaria: Cortisol and dehydroepiandrosterone levels. ( de Mendonça, BB; de Souza, JM; Libonati, RM; Maués, JA; Quaresma, JA, 2006) |
| "Dehydroepiandrosterone (DHEA) was utilised for inhibiting the G6PD activity of erythrocytes." | 1.46 | The effect and mechanism of inhibiting glucose-6-phosphate dehydrogenase activity on the proliferation of Plasmodium falciparum. ( Chen, X; Fang, Z; Feng, Y; Jiang, C; Jiang, W; Zhang, Z, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Z | 1 |
| Chen, X | 1 |
| Jiang, C | 1 |
| Fang, Z | 1 |
| Feng, Y | 1 |
| Jiang, W | 1 |
| Ayi, K | 1 |
| Giribaldi, G | 1 |
| Skorokhod, A | 1 |
| Schwarzer, E | 1 |
| Prendergast, PT | 1 |
| Arese, P | 1 |
| Libonati, RM | 1 |
| de Mendonça, BB | 1 |
| Maués, JA | 1 |
| Quaresma, JA | 1 |
| de Souza, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Etude de l'Activite (Efficacite et Tolerance) de l'Association de la Chloroquine Avec la Dehydroepiandrosterone-Sulfate (Dheas) Dans le Traitement de l'Acces Palustre Simple A Plasmodium Falciparum[NCT00442403] | Phase 3 | 200 participants | Interventional | 2002-04-30 | Suspended (stopped due to At the end of the year 2002, Cameroon switched from chloroquine to amodiaquine as first-line therapy for of uncomplicated malaria.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for dehydroepiandrosterone and Plasmodium falciparum Malaria
| Article | Year |
|---|---|
The effect and mechanism of inhibiting glucose-6-phosphate dehydrogenase activity on the proliferation of Plasmodium falciparum.
Topics: Antimalarials; Cells, Cultured; Dehydroepiandrosterone; Erythrocyte Membrane; Erythrocytes; Glucosep | 2017 |
16alpha-bromoepiandrosterone, an antimalarial analogue of the hormone dehydroepiandrosterone, enhances phagocytosis of ring stage parasitized erythrocytes: a novel mechanism for antimalarial activity.
Topics: Adult; Androsterone; Animals; Antimalarials; Cell Membrane; Dehydroepiandrosterone; Dehydroepiandros | 2002 |
Some aspects of the behavior of the hypothalamus-pituitary-adrenal axis in patients with uncomplicated Plasmodium falciparum malaria: Cortisol and dehydroepiandrosterone levels.
Topics: Adolescent; Adult; Animals; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hypothalamo-Hypo | 2006 |