Page last updated: 2024-11-07

dehydroepiandrosterone and Parkinson Disease

dehydroepiandrosterone has been researched along with Parkinson Disease in 3 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Panagiotakopoulou, V1
Botsakis, K1
Delis, F1
Mourtzi, T1
Tzatzarakis, MN1
Dimopoulou, A1
Poulia, N1
Antoniou, K1
Stathopoulos, GT1
Matsokis, N1
Charalampopoulos, I1
Gravanis, A1
Angelatou, F1
Azuma, T1
Matsubara, T1
Shima, Y1
Haeno, S1
Fujimoto, T1
Tone, K1
Shibata, N1
Sakoda, S1
Cyr, M1
Calon, F1
Morissette, M1
Grandbois, M1
Di Paolo, T1
Callier, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Early Mental Response to Hormonal Treatment in Transgender Men - The EMRE Study[NCT05649605]70 participants (Anticipated)Interventional2023-03-07Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for dehydroepiandrosterone and Parkinson Disease

ArticleYear
Drugs with estrogen-like potency and brain activity: potential therapeutic application for the CNS.
    Current pharmaceutical design, 2000, Volume: 6, Issue:12

    Topics: Alzheimer Disease; Animals; Brain; Dehydroepiandrosterone; Depression; Estrogens; Female; Humans; Ma

2000

Other Studies

2 other studies available for dehydroepiandrosterone and Parkinson Disease

ArticleYear
Anti-neuroinflammatory, protective effects of the synthetic microneurotrophin BNN-20 in the advanced dopaminergic neurodegeneration of "weaver" mice.
    Neuropharmacology, 2020, 03-15, Volume: 165

    Topics: Animals; Anti-Inflammatory Agents; Brain-Derived Neurotrophic Factor; Dehydroepiandrosterone; Diseas

2020
Neurosteroids in cerebrospinal fluid in neurologic disorders.
    Journal of the neurological sciences, 1993, Dec-01, Volume: 120, Issue:1

    Topics: Adult; Age Factors; Aged; Brain Neoplasms; Cerebellar Diseases; Cerebral Infarction; Dehydroepiandro

1993